Application of histology-agnostic treatments in metastatic colorectal cancer
Cancer treatment is increasingly focused on targeting molecular alterations identified across different tumor histologies. While some oncogenic drivers such as microsatellite instability (MSI) and NTRK fusions are actionable with the very same approach regardless of tumor type (“histology-agnostic”)...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Sartore-Bianchi, Andrea [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2022 |
|---|
| Umfang: |
13 |
|---|
| Übergeordnetes Werk: |
Enthalten in: The relationship between physical performance and cardiac function in an elderly Russian cohort - Tadjibaev, Pulod ELSEVIER, 2014, official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, [S.l.] |
|---|---|
| Übergeordnetes Werk: |
volume:54 ; year:2022 ; number:10 ; pages:1291-1303 ; extent:13 |
| Links: |
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| DOI / URN: |
10.1016/j.dld.2022.05.013 |
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Cancer treatment is increasingly focused on targeting molecular alterations identified across different tumor histologies. While some oncogenic drivers such as microsatellite instability (MSI) and NTRK fusions are actionable with the very same approach regardless of tumor type (“histology-agnostic”), others require histology-specific therapeutic adjustment (“histology-tuned”) by means of adopting specific inhibitors and ad hoc combinations. |
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Cancer treatment is increasingly focused on targeting molecular alterations identified across different tumor histologies. While some oncogenic drivers such as microsatellite instability (MSI) and NTRK fusions are actionable with the very same approach regardless of tumor type (“histology-agnostic”), others require histology-specific therapeutic adjustment (“histology-tuned”) by means of adopting specific inhibitors and ad hoc combinations. |
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