A phase III, multicenter, double-blind, randomized clinical trial to evaluate the efficacy and safety of ceftolozane/tazobactam plus metronidazole versus meropenem in Chinese participants with complicated intra-abdominal infections
• Phase III study of ceftolozane/tazobactam (C/T) plus metronidazole for complicated intra-abdominal infection in China. • C/T plus metronidazole was noninferior to meropenem for clinical response. • Safety was comparable between C/T plus metronidazole and meropenem groups. • C/T plus metronidazole...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Sun, Yihong [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2022 |
|---|
| Umfang: |
9 |
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Enthalten in: Using methylome data to inform exposome-health association studies: An application to the identification of environmental drivers of child body mass index - Cadiou, Solène ELSEVIER, 2020, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:123 ; year:2022 ; pages:157-165 ; extent:9 |
| Links: |
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| DOI / URN: |
10.1016/j.ijid.2022.08.003 |
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| author-letter |
Sun, Yihong |
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10.1016/j.ijid.2022.08.003 |
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690 610 600 |
| title_sort |
a phase iii, multicenter, double-blind, randomized clinical trial to evaluate the efficacy and safety of ceftolozane/tazobactam plus metronidazole versus meropenem in chinese participants with complicated intra-abdominal infections |
| title_auth |
A phase III, multicenter, double-blind, randomized clinical trial to evaluate the efficacy and safety of ceftolozane/tazobactam plus metronidazole versus meropenem in Chinese participants with complicated intra-abdominal infections |
| abstract |
• Phase III study of ceftolozane/tazobactam (C/T) plus metronidazole for complicated intra-abdominal infection in China. • C/T plus metronidazole was noninferior to meropenem for clinical response. • Safety was comparable between C/T plus metronidazole and meropenem groups. • C/T plus metronidazole had efficacy against extended-spectrum β-lactamase-positive Enterobacterales. |
| abstractGer |
• Phase III study of ceftolozane/tazobactam (C/T) plus metronidazole for complicated intra-abdominal infection in China. • C/T plus metronidazole was noninferior to meropenem for clinical response. • Safety was comparable between C/T plus metronidazole and meropenem groups. • C/T plus metronidazole had efficacy against extended-spectrum β-lactamase-positive Enterobacterales. |
| abstract_unstemmed |
• Phase III study of ceftolozane/tazobactam (C/T) plus metronidazole for complicated intra-abdominal infection in China. • C/T plus metronidazole was noninferior to meropenem for clinical response. • Safety was comparable between C/T plus metronidazole and meropenem groups. • C/T plus metronidazole had efficacy against extended-spectrum β-lactamase-positive Enterobacterales. |
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| title_short |
A phase III, multicenter, double-blind, randomized clinical trial to evaluate the efficacy and safety of ceftolozane/tazobactam plus metronidazole versus meropenem in Chinese participants with complicated intra-abdominal infections |
| url |
https://doi.org/10.1016/j.ijid.2022.08.003 |
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| author2 |
Fan, Jia Chen, Gang Chen, Xiaofei Du, Xiaoling Wang, Ye Wang, Hui Sun, Fang Johnson, Matthew G. Bensaci, Mekki Huntington, Jennifer A. Bruno, Christopher J. |
| author2Str |
Fan, Jia Chen, Gang Chen, Xiaofei Du, Xiaoling Wang, Ye Wang, Hui Sun, Fang Johnson, Matthew G. Bensaci, Mekki Huntington, Jennifer A. Bruno, Christopher J. |
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| doi_str |
10.1016/j.ijid.2022.08.003 |
| up_date |
2024-07-06T20:51:12.300Z |
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