The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites

Due to the limitation of the electrochemical stability window (ESW), the high potential usually led to more side reactions during the electrochemical reaction. Therefore, a novel electrochemiluminescence (ECL) sensor with wide ESW was constructed in this study. Poly(vinylidene fluoride-co-hexafluoro...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Zhu, Yunxue [verfasserIn] Wang, Peilin [verfasserIn] Ma, Qiang [verfasserIn] Zhang, Zhiquan [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Electrochemiluminescence Titanium nanoclusters MiRNA 21 Electrochemical stability window

Übergeordnetes Werk:	Enthalten in: The chemical engineering journal - Amsterdam : Elsevier, 1997, 469
Übergeordnetes Werk:	volume:469

DOI / URN:	10.1016/j.cej.2023.144025

Katalog-ID:	ELV059981024

Internformat


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245	1	0	\|a The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites
264		1	\|c 2023
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520			\|a Due to the limitation of the electrochemical stability window (ESW), the high potential usually led to more side reactions during the electrochemical reaction. Therefore, a novel electrochemiluminescence (ECL) sensor with wide ESW was constructed in this study. Poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)/silver nanowires (Ag NWs) composite was used as the substrate of the ECL biosensor. PVDF-HFP was good mechanical strength, high temperature stability and electrochemical stability. Meanwhile, Ag NWs with excellent electrical conductivity, light transmission and flexibility were employed to improve the charge transfer efficiency in the PVDF-HFP and provide binding sites for biomolecules. The optimized ESW of PVDF-HFP/Ag NWs/GCE was up to 3.717 V. Furthermore, titanium nanoclusters (Ti NCs) were synthesized and used as the aggregation-induced ECL (AIECL) probe. In addition, the biosensor achieved the good quantitative detection of miRNA 21 in ascites of gastric cancer patients within the linear range of 1 fM − 1 nM.
650		4	\|a Electrochemiluminescence
650		4	\|a Titanium nanoclusters
650		4	\|a MiRNA 21
650		4	\|a Electrochemical stability window
700	1		\|a Wang, Peilin \|e verfasserin \|4 aut
700	1		\|a Ma, Qiang \|e verfasserin \|4 aut
700	1		\|a Zhang, Zhiquan \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t The chemical engineering journal \|d Amsterdam : Elsevier, 1997 \|g 469 \|h Online-Ressource \|w (DE-627)320500322 \|w (DE-600)2012137-4 \|w (DE-576)098330152 \|x 1873-3212 \|7 nnns
773	1	8	\|g volume:469
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912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_32
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_90
912			\|a GBV_ILN_95
912			\|a GBV_ILN_100
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_150
912			\|a GBV_ILN_151
912			\|a GBV_ILN_187
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2001
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2007
912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2026
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2088
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2110
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2190
912			\|a GBV_ILN_2232
912			\|a GBV_ILN_2336
912			\|a GBV_ILN_2470
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
912			\|a GBV_ILN_4700
936	b	k	\|a 58.10 \|j Verfahrenstechnik: Allgemeines \|q VZ
951			\|a AR
952			\|d 469

Indexfelder

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matchkey_str	article:18733212:2023----::hpdhpgwbsdielcrceiasaiiyidwcssefrin2dtc
hierarchy_sort_str	2023
bklnumber	58.10
publishDate	2023
allfields	10.1016/j.cej.2023.144025 doi (DE-627)ELV059981024 (ELSEVIER)S1385-8947(23)02756-0 DE-627 ger DE-627 rda eng 660 VZ 660 VZ 58.10 bkl Zhu, Yunxue verfasserin aut The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Due to the limitation of the electrochemical stability window (ESW), the high potential usually led to more side reactions during the electrochemical reaction. Therefore, a novel electrochemiluminescence (ECL) sensor with wide ESW was constructed in this study. Poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)/silver nanowires (Ag NWs) composite was used as the substrate of the ECL biosensor. PVDF-HFP was good mechanical strength, high temperature stability and electrochemical stability. Meanwhile, Ag NWs with excellent electrical conductivity, light transmission and flexibility were employed to improve the charge transfer efficiency in the PVDF-HFP and provide binding sites for biomolecules. The optimized ESW of PVDF-HFP/Ag NWs/GCE was up to 3.717 V. Furthermore, titanium nanoclusters (Ti NCs) were synthesized and used as the aggregation-induced ECL (AIECL) probe. In addition, the biosensor achieved the good quantitative detection of miRNA 21 in ascites of gastric cancer patients within the linear range of 1 fM − 1 nM. Electrochemiluminescence Titanium nanoclusters MiRNA 21 Electrochemical stability window Wang, Peilin verfasserin aut Ma, Qiang verfasserin aut Zhang, Zhiquan verfasserin aut Enthalten in The chemical engineering journal Amsterdam : Elsevier, 1997 469 Online-Ressource (DE-627)320500322 (DE-600)2012137-4 (DE-576)098330152 1873-3212 nnns volume:469 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 58.10 Verfahrenstechnik: Allgemeines VZ AR 469
spelling	10.1016/j.cej.2023.144025 doi (DE-627)ELV059981024 (ELSEVIER)S1385-8947(23)02756-0 DE-627 ger DE-627 rda eng 660 VZ 660 VZ 58.10 bkl Zhu, Yunxue verfasserin aut The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Due to the limitation of the electrochemical stability window (ESW), the high potential usually led to more side reactions during the electrochemical reaction. Therefore, a novel electrochemiluminescence (ECL) sensor with wide ESW was constructed in this study. Poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)/silver nanowires (Ag NWs) composite was used as the substrate of the ECL biosensor. PVDF-HFP was good mechanical strength, high temperature stability and electrochemical stability. Meanwhile, Ag NWs with excellent electrical conductivity, light transmission and flexibility were employed to improve the charge transfer efficiency in the PVDF-HFP and provide binding sites for biomolecules. The optimized ESW of PVDF-HFP/Ag NWs/GCE was up to 3.717 V. Furthermore, titanium nanoclusters (Ti NCs) were synthesized and used as the aggregation-induced ECL (AIECL) probe. In addition, the biosensor achieved the good quantitative detection of miRNA 21 in ascites of gastric cancer patients within the linear range of 1 fM − 1 nM. Electrochemiluminescence Titanium nanoclusters MiRNA 21 Electrochemical stability window Wang, Peilin verfasserin aut Ma, Qiang verfasserin aut Zhang, Zhiquan verfasserin aut Enthalten in The chemical engineering journal Amsterdam : Elsevier, 1997 469 Online-Ressource (DE-627)320500322 (DE-600)2012137-4 (DE-576)098330152 1873-3212 nnns volume:469 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 58.10 Verfahrenstechnik: Allgemeines VZ AR 469
allfields_unstemmed	10.1016/j.cej.2023.144025 doi (DE-627)ELV059981024 (ELSEVIER)S1385-8947(23)02756-0 DE-627 ger DE-627 rda eng 660 VZ 660 VZ 58.10 bkl Zhu, Yunxue verfasserin aut The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Due to the limitation of the electrochemical stability window (ESW), the high potential usually led to more side reactions during the electrochemical reaction. Therefore, a novel electrochemiluminescence (ECL) sensor with wide ESW was constructed in this study. Poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)/silver nanowires (Ag NWs) composite was used as the substrate of the ECL biosensor. PVDF-HFP was good mechanical strength, high temperature stability and electrochemical stability. Meanwhile, Ag NWs with excellent electrical conductivity, light transmission and flexibility were employed to improve the charge transfer efficiency in the PVDF-HFP and provide binding sites for biomolecules. The optimized ESW of PVDF-HFP/Ag NWs/GCE was up to 3.717 V. Furthermore, titanium nanoclusters (Ti NCs) were synthesized and used as the aggregation-induced ECL (AIECL) probe. In addition, the biosensor achieved the good quantitative detection of miRNA 21 in ascites of gastric cancer patients within the linear range of 1 fM − 1 nM. Electrochemiluminescence Titanium nanoclusters MiRNA 21 Electrochemical stability window Wang, Peilin verfasserin aut Ma, Qiang verfasserin aut Zhang, Zhiquan verfasserin aut Enthalten in The chemical engineering journal Amsterdam : Elsevier, 1997 469 Online-Ressource (DE-627)320500322 (DE-600)2012137-4 (DE-576)098330152 1873-3212 nnns volume:469 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 58.10 Verfahrenstechnik: Allgemeines VZ AR 469
allfieldsGer	10.1016/j.cej.2023.144025 doi (DE-627)ELV059981024 (ELSEVIER)S1385-8947(23)02756-0 DE-627 ger DE-627 rda eng 660 VZ 660 VZ 58.10 bkl Zhu, Yunxue verfasserin aut The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Due to the limitation of the electrochemical stability window (ESW), the high potential usually led to more side reactions during the electrochemical reaction. Therefore, a novel electrochemiluminescence (ECL) sensor with wide ESW was constructed in this study. Poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)/silver nanowires (Ag NWs) composite was used as the substrate of the ECL biosensor. PVDF-HFP was good mechanical strength, high temperature stability and electrochemical stability. Meanwhile, Ag NWs with excellent electrical conductivity, light transmission and flexibility were employed to improve the charge transfer efficiency in the PVDF-HFP and provide binding sites for biomolecules. The optimized ESW of PVDF-HFP/Ag NWs/GCE was up to 3.717 V. Furthermore, titanium nanoclusters (Ti NCs) were synthesized and used as the aggregation-induced ECL (AIECL) probe. In addition, the biosensor achieved the good quantitative detection of miRNA 21 in ascites of gastric cancer patients within the linear range of 1 fM − 1 nM. Electrochemiluminescence Titanium nanoclusters MiRNA 21 Electrochemical stability window Wang, Peilin verfasserin aut Ma, Qiang verfasserin aut Zhang, Zhiquan verfasserin aut Enthalten in The chemical engineering journal Amsterdam : Elsevier, 1997 469 Online-Ressource (DE-627)320500322 (DE-600)2012137-4 (DE-576)098330152 1873-3212 nnns volume:469 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 58.10 Verfahrenstechnik: Allgemeines VZ AR 469
allfieldsSound	10.1016/j.cej.2023.144025 doi (DE-627)ELV059981024 (ELSEVIER)S1385-8947(23)02756-0 DE-627 ger DE-627 rda eng 660 VZ 660 VZ 58.10 bkl Zhu, Yunxue verfasserin aut The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Due to the limitation of the electrochemical stability window (ESW), the high potential usually led to more side reactions during the electrochemical reaction. Therefore, a novel electrochemiluminescence (ECL) sensor with wide ESW was constructed in this study. Poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)/silver nanowires (Ag NWs) composite was used as the substrate of the ECL biosensor. PVDF-HFP was good mechanical strength, high temperature stability and electrochemical stability. Meanwhile, Ag NWs with excellent electrical conductivity, light transmission and flexibility were employed to improve the charge transfer efficiency in the PVDF-HFP and provide binding sites for biomolecules. The optimized ESW of PVDF-HFP/Ag NWs/GCE was up to 3.717 V. Furthermore, titanium nanoclusters (Ti NCs) were synthesized and used as the aggregation-induced ECL (AIECL) probe. In addition, the biosensor achieved the good quantitative detection of miRNA 21 in ascites of gastric cancer patients within the linear range of 1 fM − 1 nM. Electrochemiluminescence Titanium nanoclusters MiRNA 21 Electrochemical stability window Wang, Peilin verfasserin aut Ma, Qiang verfasserin aut Zhang, Zhiquan verfasserin aut Enthalten in The chemical engineering journal Amsterdam : Elsevier, 1997 469 Online-Ressource (DE-627)320500322 (DE-600)2012137-4 (DE-576)098330152 1873-3212 nnns volume:469 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 58.10 Verfahrenstechnik: Allgemeines VZ AR 469
language	English
source	Enthalten in The chemical engineering journal 469 volume:469
sourceStr	Enthalten in The chemical engineering journal 469 volume:469
format_phy_str_mv	Article
bklname	Verfahrenstechnik: Allgemeines
institution	findex.gbv.de
topic_facet	Electrochemiluminescence Titanium nanoclusters MiRNA 21 Electrochemical stability window
dewey-raw	660
isfreeaccess_bool	false
container_title	The chemical engineering journal
authorswithroles_txt_mv	Zhu, Yunxue @@aut@@ Wang, Peilin @@aut@@ Ma, Qiang @@aut@@ Zhang, Zhiquan @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	320500322
dewey-sort	3660
id	ELV059981024
language_de	englisch
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author	Zhu, Yunxue
spellingShingle	Zhu, Yunxue ddc 660 bkl 58.10 misc Electrochemiluminescence misc Titanium nanoclusters misc MiRNA 21 misc Electrochemical stability window The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites
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topic_title	660 VZ 58.10 bkl The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites Electrochemiluminescence Titanium nanoclusters MiRNA 21 Electrochemical stability window
topic	ddc 660 bkl 58.10 misc Electrochemiluminescence misc Titanium nanoclusters misc MiRNA 21 misc Electrochemical stability window
topic_unstemmed	ddc 660 bkl 58.10 misc Electrochemiluminescence misc Titanium nanoclusters misc MiRNA 21 misc Electrochemical stability window
topic_browse	ddc 660 bkl 58.10 misc Electrochemiluminescence misc Titanium nanoclusters misc MiRNA 21 misc Electrochemical stability window
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title	The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites
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title_full	The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites
author_sort	Zhu, Yunxue
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author_browse	Zhu, Yunxue Wang, Peilin Ma, Qiang Zhang, Zhiquan
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doi_str_mv	10.1016/j.cej.2023.144025
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title_sort	the pvdf-hfp/ag nws-based wide electrochemical stability window ecl system for mirna 21 detection in gastric cancer ascites
title_auth	The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites
abstract	Due to the limitation of the electrochemical stability window (ESW), the high potential usually led to more side reactions during the electrochemical reaction. Therefore, a novel electrochemiluminescence (ECL) sensor with wide ESW was constructed in this study. Poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)/silver nanowires (Ag NWs) composite was used as the substrate of the ECL biosensor. PVDF-HFP was good mechanical strength, high temperature stability and electrochemical stability. Meanwhile, Ag NWs with excellent electrical conductivity, light transmission and flexibility were employed to improve the charge transfer efficiency in the PVDF-HFP and provide binding sites for biomolecules. The optimized ESW of PVDF-HFP/Ag NWs/GCE was up to 3.717 V. Furthermore, titanium nanoclusters (Ti NCs) were synthesized and used as the aggregation-induced ECL (AIECL) probe. In addition, the biosensor achieved the good quantitative detection of miRNA 21 in ascites of gastric cancer patients within the linear range of 1 fM − 1 nM.
abstractGer	Due to the limitation of the electrochemical stability window (ESW), the high potential usually led to more side reactions during the electrochemical reaction. Therefore, a novel electrochemiluminescence (ECL) sensor with wide ESW was constructed in this study. Poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)/silver nanowires (Ag NWs) composite was used as the substrate of the ECL biosensor. PVDF-HFP was good mechanical strength, high temperature stability and electrochemical stability. Meanwhile, Ag NWs with excellent electrical conductivity, light transmission and flexibility were employed to improve the charge transfer efficiency in the PVDF-HFP and provide binding sites for biomolecules. The optimized ESW of PVDF-HFP/Ag NWs/GCE was up to 3.717 V. Furthermore, titanium nanoclusters (Ti NCs) were synthesized and used as the aggregation-induced ECL (AIECL) probe. In addition, the biosensor achieved the good quantitative detection of miRNA 21 in ascites of gastric cancer patients within the linear range of 1 fM − 1 nM.
abstract_unstemmed	Due to the limitation of the electrochemical stability window (ESW), the high potential usually led to more side reactions during the electrochemical reaction. Therefore, a novel electrochemiluminescence (ECL) sensor with wide ESW was constructed in this study. Poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)/silver nanowires (Ag NWs) composite was used as the substrate of the ECL biosensor. PVDF-HFP was good mechanical strength, high temperature stability and electrochemical stability. Meanwhile, Ag NWs with excellent electrical conductivity, light transmission and flexibility were employed to improve the charge transfer efficiency in the PVDF-HFP and provide binding sites for biomolecules. The optimized ESW of PVDF-HFP/Ag NWs/GCE was up to 3.717 V. Furthermore, titanium nanoclusters (Ti NCs) were synthesized and used as the aggregation-induced ECL (AIECL) probe. In addition, the biosensor achieved the good quantitative detection of miRNA 21 in ascites of gastric cancer patients within the linear range of 1 fM − 1 nM.
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title_short	The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites
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author2	Wang, Peilin Ma, Qiang Zhang, Zhiquan
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doi_str	10.1016/j.cej.2023.144025
up_date	2024-07-06T23:26:28.956Z
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The PVDF-HFP/Ag NWs-based wide electrochemical stability window ECL system for miRNA 21 detection in gastric cancer ascites

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