Does parental separation moderate the heritability of health risk behavior among adolescents?

Social influences on adolescents’ health risk behavior are well documented, but little is known about the interaction of parental separation with genetic sensitivities. Using data from a German sample of 1762 twins, this study examines whether family living arrangements moderate the influence of gen...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Dierker, Philipp [verfasserIn] Kühn, Mine [verfasserIn] Mönkediek, Bastian [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Twin study Gene-environment interaction Single mothers Substance use Smoking Drug use Alcohol consumption

Übergeordnetes Werk:	Enthalten in: Social science & medicine - Amsterdam [u.a.] : Elsevier Science, 1967, 331
Übergeordnetes Werk:	volume:331

DOI / URN:	10.1016/j.socscimed.2023.116070

Katalog-ID:	ELV060897562

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245	1	0	\|a Does parental separation moderate the heritability of health risk behavior among adolescents?
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520			\|a Social influences on adolescents’ health risk behavior are well documented, but little is known about the interaction of parental separation with genetic sensitivities. Using data from a German sample of 1762 twins, this study examines whether family living arrangements moderate the influence of genetic predispositions on health risk behavior. Derived from variance decomposition moderator models, three key findings emerge. Firstly, genetic contributions to drug use are significantly higher in single-mother families, indicating an amplified heritability potentially resulting from triggered genetic sensitivities or challenges in preventing genetic risks from unfolding. Secondly, unique environmental factors have a greater impact on drug use in single-mother families. Lastly, no heritability differences are found in smoking and excessive alcohol consumption between family types. These findings provide novel evidence of increased importance of genetic influences on drug use in single-mother families, shedding light on gene-environment interactions, and informing policy interventions that support vulnerable family arrangements.
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650		4	\|a Gene-environment interaction
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allfields	10.1016/j.socscimed.2023.116070 doi (DE-627)ELV060897562 (ELSEVIER)S0277-9536(23)00427-6 DE-627 ger DE-627 rda eng Dierker, Philipp verfasserin (orcid)0000-0002-5038-7157 aut Does parental separation moderate the heritability of health risk behavior among adolescents? 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Social influences on adolescents’ health risk behavior are well documented, but little is known about the interaction of parental separation with genetic sensitivities. Using data from a German sample of 1762 twins, this study examines whether family living arrangements moderate the influence of genetic predispositions on health risk behavior. Derived from variance decomposition moderator models, three key findings emerge. Firstly, genetic contributions to drug use are significantly higher in single-mother families, indicating an amplified heritability potentially resulting from triggered genetic sensitivities or challenges in preventing genetic risks from unfolding. Secondly, unique environmental factors have a greater impact on drug use in single-mother families. Lastly, no heritability differences are found in smoking and excessive alcohol consumption between family types. These findings provide novel evidence of increased importance of genetic influences on drug use in single-mother families, shedding light on gene-environment interactions, and informing policy interventions that support vulnerable family arrangements. Twin study Gene-environment interaction Single mothers Substance use Smoking Drug use Alcohol consumption Kühn, Mine verfasserin (orcid)0000-0001-8252-7903 aut Mönkediek, Bastian verfasserin (orcid)0000-0003-4466-715X aut Enthalten in Social science & medicine Amsterdam [u.a.] : Elsevier Science, 1967 331 Online-Ressource (DE-627)306710528 (DE-600)1500748-0 (DE-576)082435901 1873-5347 nnns volume:331 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 331
spelling	10.1016/j.socscimed.2023.116070 doi (DE-627)ELV060897562 (ELSEVIER)S0277-9536(23)00427-6 DE-627 ger DE-627 rda eng Dierker, Philipp verfasserin (orcid)0000-0002-5038-7157 aut Does parental separation moderate the heritability of health risk behavior among adolescents? 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Social influences on adolescents’ health risk behavior are well documented, but little is known about the interaction of parental separation with genetic sensitivities. Using data from a German sample of 1762 twins, this study examines whether family living arrangements moderate the influence of genetic predispositions on health risk behavior. Derived from variance decomposition moderator models, three key findings emerge. Firstly, genetic contributions to drug use are significantly higher in single-mother families, indicating an amplified heritability potentially resulting from triggered genetic sensitivities or challenges in preventing genetic risks from unfolding. Secondly, unique environmental factors have a greater impact on drug use in single-mother families. Lastly, no heritability differences are found in smoking and excessive alcohol consumption between family types. These findings provide novel evidence of increased importance of genetic influences on drug use in single-mother families, shedding light on gene-environment interactions, and informing policy interventions that support vulnerable family arrangements. Twin study Gene-environment interaction Single mothers Substance use Smoking Drug use Alcohol consumption Kühn, Mine verfasserin (orcid)0000-0001-8252-7903 aut Mönkediek, Bastian verfasserin (orcid)0000-0003-4466-715X aut Enthalten in Social science & medicine Amsterdam [u.a.] : Elsevier Science, 1967 331 Online-Ressource (DE-627)306710528 (DE-600)1500748-0 (DE-576)082435901 1873-5347 nnns volume:331 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 331
allfields_unstemmed	10.1016/j.socscimed.2023.116070 doi (DE-627)ELV060897562 (ELSEVIER)S0277-9536(23)00427-6 DE-627 ger DE-627 rda eng Dierker, Philipp verfasserin (orcid)0000-0002-5038-7157 aut Does parental separation moderate the heritability of health risk behavior among adolescents? 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Social influences on adolescents’ health risk behavior are well documented, but little is known about the interaction of parental separation with genetic sensitivities. Using data from a German sample of 1762 twins, this study examines whether family living arrangements moderate the influence of genetic predispositions on health risk behavior. Derived from variance decomposition moderator models, three key findings emerge. Firstly, genetic contributions to drug use are significantly higher in single-mother families, indicating an amplified heritability potentially resulting from triggered genetic sensitivities or challenges in preventing genetic risks from unfolding. Secondly, unique environmental factors have a greater impact on drug use in single-mother families. Lastly, no heritability differences are found in smoking and excessive alcohol consumption between family types. These findings provide novel evidence of increased importance of genetic influences on drug use in single-mother families, shedding light on gene-environment interactions, and informing policy interventions that support vulnerable family arrangements. Twin study Gene-environment interaction Single mothers Substance use Smoking Drug use Alcohol consumption Kühn, Mine verfasserin (orcid)0000-0001-8252-7903 aut Mönkediek, Bastian verfasserin (orcid)0000-0003-4466-715X aut Enthalten in Social science & medicine Amsterdam [u.a.] : Elsevier Science, 1967 331 Online-Ressource (DE-627)306710528 (DE-600)1500748-0 (DE-576)082435901 1873-5347 nnns volume:331 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 331
allfieldsGer	10.1016/j.socscimed.2023.116070 doi (DE-627)ELV060897562 (ELSEVIER)S0277-9536(23)00427-6 DE-627 ger DE-627 rda eng Dierker, Philipp verfasserin (orcid)0000-0002-5038-7157 aut Does parental separation moderate the heritability of health risk behavior among adolescents? 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Social influences on adolescents’ health risk behavior are well documented, but little is known about the interaction of parental separation with genetic sensitivities. Using data from a German sample of 1762 twins, this study examines whether family living arrangements moderate the influence of genetic predispositions on health risk behavior. Derived from variance decomposition moderator models, three key findings emerge. Firstly, genetic contributions to drug use are significantly higher in single-mother families, indicating an amplified heritability potentially resulting from triggered genetic sensitivities or challenges in preventing genetic risks from unfolding. Secondly, unique environmental factors have a greater impact on drug use in single-mother families. Lastly, no heritability differences are found in smoking and excessive alcohol consumption between family types. These findings provide novel evidence of increased importance of genetic influences on drug use in single-mother families, shedding light on gene-environment interactions, and informing policy interventions that support vulnerable family arrangements. Twin study Gene-environment interaction Single mothers Substance use Smoking Drug use Alcohol consumption Kühn, Mine verfasserin (orcid)0000-0001-8252-7903 aut Mönkediek, Bastian verfasserin (orcid)0000-0003-4466-715X aut Enthalten in Social science & medicine Amsterdam [u.a.] : Elsevier Science, 1967 331 Online-Ressource (DE-627)306710528 (DE-600)1500748-0 (DE-576)082435901 1873-5347 nnns volume:331 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 331
allfieldsSound	10.1016/j.socscimed.2023.116070 doi (DE-627)ELV060897562 (ELSEVIER)S0277-9536(23)00427-6 DE-627 ger DE-627 rda eng Dierker, Philipp verfasserin (orcid)0000-0002-5038-7157 aut Does parental separation moderate the heritability of health risk behavior among adolescents? 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Social influences on adolescents’ health risk behavior are well documented, but little is known about the interaction of parental separation with genetic sensitivities. Using data from a German sample of 1762 twins, this study examines whether family living arrangements moderate the influence of genetic predispositions on health risk behavior. Derived from variance decomposition moderator models, three key findings emerge. Firstly, genetic contributions to drug use are significantly higher in single-mother families, indicating an amplified heritability potentially resulting from triggered genetic sensitivities or challenges in preventing genetic risks from unfolding. Secondly, unique environmental factors have a greater impact on drug use in single-mother families. Lastly, no heritability differences are found in smoking and excessive alcohol consumption between family types. These findings provide novel evidence of increased importance of genetic influences on drug use in single-mother families, shedding light on gene-environment interactions, and informing policy interventions that support vulnerable family arrangements. Twin study Gene-environment interaction Single mothers Substance use Smoking Drug use Alcohol consumption Kühn, Mine verfasserin (orcid)0000-0001-8252-7903 aut Mönkediek, Bastian verfasserin (orcid)0000-0003-4466-715X aut Enthalten in Social science & medicine Amsterdam [u.a.] : Elsevier Science, 1967 331 Online-Ressource (DE-627)306710528 (DE-600)1500748-0 (DE-576)082435901 1873-5347 nnns volume:331 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 331
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spellingShingle	Dierker, Philipp misc Twin study misc Gene-environment interaction misc Single mothers misc Substance use misc Smoking misc Drug use misc Alcohol consumption Does parental separation moderate the heritability of health risk behavior among adolescents?
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topic_title	Does parental separation moderate the heritability of health risk behavior among adolescents? Twin study Gene-environment interaction Single mothers Substance use Smoking Drug use Alcohol consumption
topic	misc Twin study misc Gene-environment interaction misc Single mothers misc Substance use misc Smoking misc Drug use misc Alcohol consumption
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title_full	Does parental separation moderate the heritability of health risk behavior among adolescents?
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title_sort	does parental separation moderate the heritability of health risk behavior among adolescents?
title_auth	Does parental separation moderate the heritability of health risk behavior among adolescents?
abstract	Social influences on adolescents’ health risk behavior are well documented, but little is known about the interaction of parental separation with genetic sensitivities. Using data from a German sample of 1762 twins, this study examines whether family living arrangements moderate the influence of genetic predispositions on health risk behavior. Derived from variance decomposition moderator models, three key findings emerge. Firstly, genetic contributions to drug use are significantly higher in single-mother families, indicating an amplified heritability potentially resulting from triggered genetic sensitivities or challenges in preventing genetic risks from unfolding. Secondly, unique environmental factors have a greater impact on drug use in single-mother families. Lastly, no heritability differences are found in smoking and excessive alcohol consumption between family types. These findings provide novel evidence of increased importance of genetic influences on drug use in single-mother families, shedding light on gene-environment interactions, and informing policy interventions that support vulnerable family arrangements.
abstractGer	Social influences on adolescents’ health risk behavior are well documented, but little is known about the interaction of parental separation with genetic sensitivities. Using data from a German sample of 1762 twins, this study examines whether family living arrangements moderate the influence of genetic predispositions on health risk behavior. Derived from variance decomposition moderator models, three key findings emerge. Firstly, genetic contributions to drug use are significantly higher in single-mother families, indicating an amplified heritability potentially resulting from triggered genetic sensitivities or challenges in preventing genetic risks from unfolding. Secondly, unique environmental factors have a greater impact on drug use in single-mother families. Lastly, no heritability differences are found in smoking and excessive alcohol consumption between family types. These findings provide novel evidence of increased importance of genetic influences on drug use in single-mother families, shedding light on gene-environment interactions, and informing policy interventions that support vulnerable family arrangements.
abstract_unstemmed	Social influences on adolescents’ health risk behavior are well documented, but little is known about the interaction of parental separation with genetic sensitivities. Using data from a German sample of 1762 twins, this study examines whether family living arrangements moderate the influence of genetic predispositions on health risk behavior. Derived from variance decomposition moderator models, three key findings emerge. Firstly, genetic contributions to drug use are significantly higher in single-mother families, indicating an amplified heritability potentially resulting from triggered genetic sensitivities or challenges in preventing genetic risks from unfolding. Secondly, unique environmental factors have a greater impact on drug use in single-mother families. Lastly, no heritability differences are found in smoking and excessive alcohol consumption between family types. These findings provide novel evidence of increased importance of genetic influences on drug use in single-mother families, shedding light on gene-environment interactions, and informing policy interventions that support vulnerable family arrangements.
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title_short	Does parental separation moderate the heritability of health risk behavior among adolescents?
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Does parental separation moderate the heritability of health risk behavior among adolescents?

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