Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis
Background: Amyloid light-chain cardiac amyloidosis (AL-CA) patients experiencing RV failure have a poorer prognosis. The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the cou...
Ausführliche Beschreibung
Autor*in: |
Yu, Fangcong [verfasserIn] Cui, Yawei [verfasserIn] Shi, Jiaran [verfasserIn] Wang, Longbo [verfasserIn] Zhou, Yunping [verfasserIn] Ye, Tianxin [verfasserIn] Ye, Zhehao [verfasserIn] Yang, Jinxiu [verfasserIn] Wang, Xingxiang [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2023 |
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Schlagwörter: |
Light-chain cardiac amyloidosis (AL-CA) Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) |
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Übergeordnetes Werk: |
Enthalten in: International journal of cardiology - Amsterdam [u.a.] : Elsevier Science, 1981, 387 |
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Übergeordnetes Werk: |
volume:387 |
DOI / URN: |
10.1016/j.ijcard.2023.05.058 |
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Katalog-ID: |
ELV060944668 |
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245 | 1 | 0 | |a Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis |
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520 | |a Background: Amyloid light-chain cardiac amyloidosis (AL-CA) patients experiencing RV failure have a poorer prognosis. The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. The combination of TAPSE/PASP ratio < 0.474 mmHg and SBP < 100 mmHg could identify the subgroup of patients with AL-CA at elevated risk of poor prognosis. | ||
650 | 4 | |a Light-chain cardiac amyloidosis (AL-CA) | |
650 | 4 | |a Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) | |
650 | 4 | |a Systolic blood pressure(SBP) | |
650 | 4 | |a Short-term outcome | |
700 | 1 | |a Cui, Yawei |e verfasserin |4 aut | |
700 | 1 | |a Shi, Jiaran |e verfasserin |4 aut | |
700 | 1 | |a Wang, Longbo |e verfasserin |4 aut | |
700 | 1 | |a Zhou, Yunping |e verfasserin |4 aut | |
700 | 1 | |a Ye, Tianxin |e verfasserin |4 aut | |
700 | 1 | |a Ye, Zhehao |e verfasserin |4 aut | |
700 | 1 | |a Yang, Jinxiu |e verfasserin |4 aut | |
700 | 1 | |a Wang, Xingxiang |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t International journal of cardiology |d Amsterdam [u.a.] : Elsevier Science, 1981 |g 387 |h Online-Ressource |w (DE-627)306659581 |w (DE-600)1500478-8 |w (DE-576)081986270 |x 1874-1754 |7 nnns |
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allfields |
10.1016/j.ijcard.2023.05.058 doi (DE-627)ELV060944668 (ELSEVIER)S0167-5273(23)00790-8 DE-627 ger DE-627 rda eng 610 VZ 44.85 bkl Yu, Fangcong verfasserin aut Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Amyloid light-chain cardiac amyloidosis (AL-CA) patients experiencing RV failure have a poorer prognosis. The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. The combination of TAPSE/PASP ratio < 0.474 mmHg and SBP < 100 mmHg could identify the subgroup of patients with AL-CA at elevated risk of poor prognosis. Light-chain cardiac amyloidosis (AL-CA) Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) Systolic blood pressure(SBP) Short-term outcome Cui, Yawei verfasserin aut Shi, Jiaran verfasserin aut Wang, Longbo verfasserin aut Zhou, Yunping verfasserin aut Ye, Tianxin verfasserin aut Ye, Zhehao verfasserin aut Yang, Jinxiu verfasserin aut Wang, Xingxiang verfasserin aut Enthalten in International journal of cardiology Amsterdam [u.a.] : Elsevier Science, 1981 387 Online-Ressource (DE-627)306659581 (DE-600)1500478-8 (DE-576)081986270 1874-1754 nnns volume:387 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.85 Kardiologie Angiologie VZ AR 387 |
spelling |
10.1016/j.ijcard.2023.05.058 doi (DE-627)ELV060944668 (ELSEVIER)S0167-5273(23)00790-8 DE-627 ger DE-627 rda eng 610 VZ 44.85 bkl Yu, Fangcong verfasserin aut Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Amyloid light-chain cardiac amyloidosis (AL-CA) patients experiencing RV failure have a poorer prognosis. The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. The combination of TAPSE/PASP ratio < 0.474 mmHg and SBP < 100 mmHg could identify the subgroup of patients with AL-CA at elevated risk of poor prognosis. Light-chain cardiac amyloidosis (AL-CA) Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) Systolic blood pressure(SBP) Short-term outcome Cui, Yawei verfasserin aut Shi, Jiaran verfasserin aut Wang, Longbo verfasserin aut Zhou, Yunping verfasserin aut Ye, Tianxin verfasserin aut Ye, Zhehao verfasserin aut Yang, Jinxiu verfasserin aut Wang, Xingxiang verfasserin aut Enthalten in International journal of cardiology Amsterdam [u.a.] : Elsevier Science, 1981 387 Online-Ressource (DE-627)306659581 (DE-600)1500478-8 (DE-576)081986270 1874-1754 nnns volume:387 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.85 Kardiologie Angiologie VZ AR 387 |
allfields_unstemmed |
10.1016/j.ijcard.2023.05.058 doi (DE-627)ELV060944668 (ELSEVIER)S0167-5273(23)00790-8 DE-627 ger DE-627 rda eng 610 VZ 44.85 bkl Yu, Fangcong verfasserin aut Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Amyloid light-chain cardiac amyloidosis (AL-CA) patients experiencing RV failure have a poorer prognosis. The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. The combination of TAPSE/PASP ratio < 0.474 mmHg and SBP < 100 mmHg could identify the subgroup of patients with AL-CA at elevated risk of poor prognosis. Light-chain cardiac amyloidosis (AL-CA) Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) Systolic blood pressure(SBP) Short-term outcome Cui, Yawei verfasserin aut Shi, Jiaran verfasserin aut Wang, Longbo verfasserin aut Zhou, Yunping verfasserin aut Ye, Tianxin verfasserin aut Ye, Zhehao verfasserin aut Yang, Jinxiu verfasserin aut Wang, Xingxiang verfasserin aut Enthalten in International journal of cardiology Amsterdam [u.a.] : Elsevier Science, 1981 387 Online-Ressource (DE-627)306659581 (DE-600)1500478-8 (DE-576)081986270 1874-1754 nnns volume:387 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.85 Kardiologie Angiologie VZ AR 387 |
allfieldsGer |
10.1016/j.ijcard.2023.05.058 doi (DE-627)ELV060944668 (ELSEVIER)S0167-5273(23)00790-8 DE-627 ger DE-627 rda eng 610 VZ 44.85 bkl Yu, Fangcong verfasserin aut Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Amyloid light-chain cardiac amyloidosis (AL-CA) patients experiencing RV failure have a poorer prognosis. The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. The combination of TAPSE/PASP ratio < 0.474 mmHg and SBP < 100 mmHg could identify the subgroup of patients with AL-CA at elevated risk of poor prognosis. Light-chain cardiac amyloidosis (AL-CA) Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) Systolic blood pressure(SBP) Short-term outcome Cui, Yawei verfasserin aut Shi, Jiaran verfasserin aut Wang, Longbo verfasserin aut Zhou, Yunping verfasserin aut Ye, Tianxin verfasserin aut Ye, Zhehao verfasserin aut Yang, Jinxiu verfasserin aut Wang, Xingxiang verfasserin aut Enthalten in International journal of cardiology Amsterdam [u.a.] : Elsevier Science, 1981 387 Online-Ressource (DE-627)306659581 (DE-600)1500478-8 (DE-576)081986270 1874-1754 nnns volume:387 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.85 Kardiologie Angiologie VZ AR 387 |
allfieldsSound |
10.1016/j.ijcard.2023.05.058 doi (DE-627)ELV060944668 (ELSEVIER)S0167-5273(23)00790-8 DE-627 ger DE-627 rda eng 610 VZ 44.85 bkl Yu, Fangcong verfasserin aut Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Amyloid light-chain cardiac amyloidosis (AL-CA) patients experiencing RV failure have a poorer prognosis. The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. The combination of TAPSE/PASP ratio < 0.474 mmHg and SBP < 100 mmHg could identify the subgroup of patients with AL-CA at elevated risk of poor prognosis. Light-chain cardiac amyloidosis (AL-CA) Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) Systolic blood pressure(SBP) Short-term outcome Cui, Yawei verfasserin aut Shi, Jiaran verfasserin aut Wang, Longbo verfasserin aut Zhou, Yunping verfasserin aut Ye, Tianxin verfasserin aut Ye, Zhehao verfasserin aut Yang, Jinxiu verfasserin aut Wang, Xingxiang verfasserin aut Enthalten in International journal of cardiology Amsterdam [u.a.] : Elsevier Science, 1981 387 Online-Ressource (DE-627)306659581 (DE-600)1500478-8 (DE-576)081986270 1874-1754 nnns volume:387 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.85 Kardiologie Angiologie VZ AR 387 |
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Light-chain cardiac amyloidosis (AL-CA) Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) Systolic blood pressure(SBP) Short-term outcome |
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Yu, Fangcong @@aut@@ Cui, Yawei @@aut@@ Shi, Jiaran @@aut@@ Wang, Longbo @@aut@@ Zhou, Yunping @@aut@@ Ye, Tianxin @@aut@@ Ye, Zhehao @@aut@@ Yang, Jinxiu @@aut@@ Wang, Xingxiang @@aut@@ |
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2023-01-01T00:00:00Z |
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The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. 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Yu, Fangcong |
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Yu, Fangcong ddc 610 bkl 44.85 misc Light-chain cardiac amyloidosis (AL-CA) misc Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) misc Systolic blood pressure(SBP) misc Short-term outcome Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis |
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610 VZ 44.85 bkl Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis Light-chain cardiac amyloidosis (AL-CA) Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) Systolic blood pressure(SBP) Short-term outcome |
topic |
ddc 610 bkl 44.85 misc Light-chain cardiac amyloidosis (AL-CA) misc Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) misc Systolic blood pressure(SBP) misc Short-term outcome |
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ddc 610 bkl 44.85 misc Light-chain cardiac amyloidosis (AL-CA) misc Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) misc Systolic blood pressure(SBP) misc Short-term outcome |
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ddc 610 bkl 44.85 misc Light-chain cardiac amyloidosis (AL-CA) misc Tricuspid annular plane systolic excursion(TAPSE);pulmonary arterial systolic pressure(PASP) misc Systolic blood pressure(SBP) misc Short-term outcome |
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Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis |
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Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis |
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Yu, Fangcong |
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Yu, Fangcong Cui, Yawei Shi, Jiaran Wang, Longbo Zhou, Yunping Ye, Tianxin Ye, Zhehao Yang, Jinxiu Wang, Xingxiang |
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association between the tapse to pasp ratio and short-term outcome in patients with light-chain cardiac amyloidosis |
title_auth |
Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis |
abstract |
Background: Amyloid light-chain cardiac amyloidosis (AL-CA) patients experiencing RV failure have a poorer prognosis. The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. The combination of TAPSE/PASP ratio < 0.474 mmHg and SBP < 100 mmHg could identify the subgroup of patients with AL-CA at elevated risk of poor prognosis. |
abstractGer |
Background: Amyloid light-chain cardiac amyloidosis (AL-CA) patients experiencing RV failure have a poorer prognosis. The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. The combination of TAPSE/PASP ratio < 0.474 mmHg and SBP < 100 mmHg could identify the subgroup of patients with AL-CA at elevated risk of poor prognosis. |
abstract_unstemmed |
Background: Amyloid light-chain cardiac amyloidosis (AL-CA) patients experiencing RV failure have a poorer prognosis. The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. The combination of TAPSE/PASP ratio < 0.474 mmHg and SBP < 100 mmHg could identify the subgroup of patients with AL-CA at elevated risk of poor prognosis. |
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title_short |
Association between the TAPSE to PASP ratio and short-term outcome in patients with light-chain cardiac amyloidosis |
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Cui, Yawei Shi, Jiaran Wang, Longbo Zhou, Yunping Ye, Tianxin Ye, Zhehao Yang, Jinxiu Wang, Xingxiang |
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The echocardiographic ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) serves as a non-invasive proxy for evaluating the coupling between the right ventricle (RV) and pulmonary circulation. The aim of this study was to assess the association between the TAPSE/PASP ratio and short-term outcome in patients with AL-CA.Methods: Seventy-one patients diagnosed with AL-CA were enrolled in this retrospective cohort study.Short-term outcome was defined as 6-month all-cause mortality. Receiver operating characteristic (ROC), logistic regression, and Kaplan-Meier analysis were used in this study.Results: Among seventy-one patients with AL-CA (mean age, 62 ± 8 years, 69% male), 17 (24%) died within the first 6 months (mean follow-up period 55 ± 48 days). Linear regression analysis indicated that the TAPSE/PASP ratio was correlated with RV global longitudinal strain (r = −0.655, p < 0.001), RV free wall thickness (r = −0.599, p < 0.001), and left atrial reservoir strain (r = 0.770, p < 0.001). The time-dependent ROC and the area under the curve (AUC) showed that the TAPSE/PASP ratio was a better predictor (AUC = 0.798; 95% confidence interval (CI): 0.677–0.929) of short-term outcome than TAPSE (AUC = 0.734; 95% CI: 0.585–0.882) and PASP (AUC: 0.730; 95% CI: 0.587–0.874). Multivariate logistic regression showed that patients with the worse TAPSE/PASP (< 0.47 mm/mmHg) and lower systolic blood pressure (< 100 mmHg) had the highest risk of dying.Conclusions: The TAPSE/PASP ratio is associated with the short-term outcome of patients with AL-CA. 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7.4015627 |