Oxidative stress markers in the saliva of patients with oral lichen planus

Objective: To evaluate the levels of oxidative stress markers in the saliva of patients with oral lichen planus (OLP).Methods: A cross-sectional study was conducted with 22 patients diagnosed both clinically and histologically with OLP (reticular or erosive) and 12 individuals without OLP. Non-stimu...
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Autor*in:	Gonzaga, Amanda Katarinny Goes [verfasserIn] Vasconcelos, Roseane Carvalho [verfasserIn] Lopes, Maria Luiza Diniz de Sousa [verfasserIn] Medeiros, Maurília Raquel de Souto [verfasserIn] de Araújo, Aurigena Antunes [verfasserIn] da Silveira, Éricka Janine Dantas [verfasserIn] de Medeiros, Ana Miryam Costa [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Lichen planus Oxidative stress Lipid peroxidation Saliva

Übergeordnetes Werk:	Enthalten in: Pathology, research and practice - München : Elsevier, 1978, 248
Übergeordnetes Werk:	volume:248

DOI / URN:	10.1016/j.prp.2023.154569

Katalog-ID:	ELV061526134

Internformat


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245	1	0	\|a Oxidative stress markers in the saliva of patients with oral lichen planus
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520			\|a Objective: To evaluate the levels of oxidative stress markers in the saliva of patients with oral lichen planus (OLP).Methods: A cross-sectional study was conducted with 22 patients diagnosed both clinically and histologically with OLP (reticular or erosive) and 12 individuals without OLP. Non-stimulated sialometry was performed and oxidative stress (myeloperoxidase - MPO and malondialdehyde - MDA) and antioxidant (superoxide dismutase - SOD and glutathione - GSH) markers were determined in the saliva.Results: Among the patients with OLP, most were women (n = 19; 86.4%) and reported to have experienced menopause (63.2%). Patients with OLP were mostly in the active stage of the disease (n = 17; 77.3%) and the reticular form was predominant (n = 15; 68.2%). No statistically significant differences were observed when comparing SOD, GSH, MPO and MDA values between individuals with and without OLP, as well as between erosive and reticular forms of OLP (p > 0.05). Patients with inactive OLP presented higher SOD when compared to those with active disease (p = 0.031).Conclusion: Oxidative stress markers in the saliva of patients with OLP were similar to those found in people without OLP, which can be related to the high exposure of the oral cavity environment to several physical, chemical and microbiological stimuli, important generators of the oxidative stress.
650		4	\|a Lichen planus
650		4	\|a Oxidative stress
650		4	\|a Lipid peroxidation
650		4	\|a Saliva
700	1		\|a Vasconcelos, Roseane Carvalho \|e verfasserin \|4 aut
700	1		\|a Lopes, Maria Luiza Diniz de Sousa \|e verfasserin \|4 aut
700	1		\|a Medeiros, Maurília Raquel de Souto \|e verfasserin \|4 aut
700	1		\|a de Araújo, Aurigena Antunes \|e verfasserin \|4 aut
700	1		\|a da Silveira, Éricka Janine Dantas \|e verfasserin \|4 aut
700	1		\|a de Medeiros, Ana Miryam Costa \|e verfasserin \|4 aut
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912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
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912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
912			\|a GBV_ILN_4700
936	b	k	\|a 44.47 \|j Pathologie \|x Medizin \|q VZ
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allfields	10.1016/j.prp.2023.154569 doi (DE-627)ELV061526134 (ELSEVIER)S0344-0338(23)00269-8 DE-627 ger DE-627 rda eng 610 VZ 44.47 bkl Gonzaga, Amanda Katarinny Goes verfasserin aut Oxidative stress markers in the saliva of patients with oral lichen planus 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the levels of oxidative stress markers in the saliva of patients with oral lichen planus (OLP).Methods: A cross-sectional study was conducted with 22 patients diagnosed both clinically and histologically with OLP (reticular or erosive) and 12 individuals without OLP. Non-stimulated sialometry was performed and oxidative stress (myeloperoxidase - MPO and malondialdehyde - MDA) and antioxidant (superoxide dismutase - SOD and glutathione - GSH) markers were determined in the saliva.Results: Among the patients with OLP, most were women (n = 19; 86.4%) and reported to have experienced menopause (63.2%). Patients with OLP were mostly in the active stage of the disease (n = 17; 77.3%) and the reticular form was predominant (n = 15; 68.2%). No statistically significant differences were observed when comparing SOD, GSH, MPO and MDA values between individuals with and without OLP, as well as between erosive and reticular forms of OLP (p > 0.05). Patients with inactive OLP presented higher SOD when compared to those with active disease (p = 0.031).Conclusion: Oxidative stress markers in the saliva of patients with OLP were similar to those found in people without OLP, which can be related to the high exposure of the oral cavity environment to several physical, chemical and microbiological stimuli, important generators of the oxidative stress. Lichen planus Oxidative stress Lipid peroxidation Saliva Vasconcelos, Roseane Carvalho verfasserin aut Lopes, Maria Luiza Diniz de Sousa verfasserin aut Medeiros, Maurília Raquel de Souto verfasserin aut de Araújo, Aurigena Antunes verfasserin aut da Silveira, Éricka Janine Dantas verfasserin aut de Medeiros, Ana Miryam Costa verfasserin aut Enthalten in Pathology, research and practice München : Elsevier, 1978 248 Online-Ressource (DE-627)325789517 (DE-600)2039756-2 (DE-576)094480672 1618-0631 nnns volume:248 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.47 Pathologie Medizin VZ AR 248
spelling	10.1016/j.prp.2023.154569 doi (DE-627)ELV061526134 (ELSEVIER)S0344-0338(23)00269-8 DE-627 ger DE-627 rda eng 610 VZ 44.47 bkl Gonzaga, Amanda Katarinny Goes verfasserin aut Oxidative stress markers in the saliva of patients with oral lichen planus 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the levels of oxidative stress markers in the saliva of patients with oral lichen planus (OLP).Methods: A cross-sectional study was conducted with 22 patients diagnosed both clinically and histologically with OLP (reticular or erosive) and 12 individuals without OLP. Non-stimulated sialometry was performed and oxidative stress (myeloperoxidase - MPO and malondialdehyde - MDA) and antioxidant (superoxide dismutase - SOD and glutathione - GSH) markers were determined in the saliva.Results: Among the patients with OLP, most were women (n = 19; 86.4%) and reported to have experienced menopause (63.2%). Patients with OLP were mostly in the active stage of the disease (n = 17; 77.3%) and the reticular form was predominant (n = 15; 68.2%). No statistically significant differences were observed when comparing SOD, GSH, MPO and MDA values between individuals with and without OLP, as well as between erosive and reticular forms of OLP (p > 0.05). Patients with inactive OLP presented higher SOD when compared to those with active disease (p = 0.031).Conclusion: Oxidative stress markers in the saliva of patients with OLP were similar to those found in people without OLP, which can be related to the high exposure of the oral cavity environment to several physical, chemical and microbiological stimuli, important generators of the oxidative stress. Lichen planus Oxidative stress Lipid peroxidation Saliva Vasconcelos, Roseane Carvalho verfasserin aut Lopes, Maria Luiza Diniz de Sousa verfasserin aut Medeiros, Maurília Raquel de Souto verfasserin aut de Araújo, Aurigena Antunes verfasserin aut da Silveira, Éricka Janine Dantas verfasserin aut de Medeiros, Ana Miryam Costa verfasserin aut Enthalten in Pathology, research and practice München : Elsevier, 1978 248 Online-Ressource (DE-627)325789517 (DE-600)2039756-2 (DE-576)094480672 1618-0631 nnns volume:248 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.47 Pathologie Medizin VZ AR 248
allfields_unstemmed	10.1016/j.prp.2023.154569 doi (DE-627)ELV061526134 (ELSEVIER)S0344-0338(23)00269-8 DE-627 ger DE-627 rda eng 610 VZ 44.47 bkl Gonzaga, Amanda Katarinny Goes verfasserin aut Oxidative stress markers in the saliva of patients with oral lichen planus 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the levels of oxidative stress markers in the saliva of patients with oral lichen planus (OLP).Methods: A cross-sectional study was conducted with 22 patients diagnosed both clinically and histologically with OLP (reticular or erosive) and 12 individuals without OLP. Non-stimulated sialometry was performed and oxidative stress (myeloperoxidase - MPO and malondialdehyde - MDA) and antioxidant (superoxide dismutase - SOD and glutathione - GSH) markers were determined in the saliva.Results: Among the patients with OLP, most were women (n = 19; 86.4%) and reported to have experienced menopause (63.2%). Patients with OLP were mostly in the active stage of the disease (n = 17; 77.3%) and the reticular form was predominant (n = 15; 68.2%). No statistically significant differences were observed when comparing SOD, GSH, MPO and MDA values between individuals with and without OLP, as well as between erosive and reticular forms of OLP (p > 0.05). Patients with inactive OLP presented higher SOD when compared to those with active disease (p = 0.031).Conclusion: Oxidative stress markers in the saliva of patients with OLP were similar to those found in people without OLP, which can be related to the high exposure of the oral cavity environment to several physical, chemical and microbiological stimuli, important generators of the oxidative stress. Lichen planus Oxidative stress Lipid peroxidation Saliva Vasconcelos, Roseane Carvalho verfasserin aut Lopes, Maria Luiza Diniz de Sousa verfasserin aut Medeiros, Maurília Raquel de Souto verfasserin aut de Araújo, Aurigena Antunes verfasserin aut da Silveira, Éricka Janine Dantas verfasserin aut de Medeiros, Ana Miryam Costa verfasserin aut Enthalten in Pathology, research and practice München : Elsevier, 1978 248 Online-Ressource (DE-627)325789517 (DE-600)2039756-2 (DE-576)094480672 1618-0631 nnns volume:248 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.47 Pathologie Medizin VZ AR 248
allfieldsGer	10.1016/j.prp.2023.154569 doi (DE-627)ELV061526134 (ELSEVIER)S0344-0338(23)00269-8 DE-627 ger DE-627 rda eng 610 VZ 44.47 bkl Gonzaga, Amanda Katarinny Goes verfasserin aut Oxidative stress markers in the saliva of patients with oral lichen planus 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the levels of oxidative stress markers in the saliva of patients with oral lichen planus (OLP).Methods: A cross-sectional study was conducted with 22 patients diagnosed both clinically and histologically with OLP (reticular or erosive) and 12 individuals without OLP. Non-stimulated sialometry was performed and oxidative stress (myeloperoxidase - MPO and malondialdehyde - MDA) and antioxidant (superoxide dismutase - SOD and glutathione - GSH) markers were determined in the saliva.Results: Among the patients with OLP, most were women (n = 19; 86.4%) and reported to have experienced menopause (63.2%). Patients with OLP were mostly in the active stage of the disease (n = 17; 77.3%) and the reticular form was predominant (n = 15; 68.2%). No statistically significant differences were observed when comparing SOD, GSH, MPO and MDA values between individuals with and without OLP, as well as between erosive and reticular forms of OLP (p > 0.05). Patients with inactive OLP presented higher SOD when compared to those with active disease (p = 0.031).Conclusion: Oxidative stress markers in the saliva of patients with OLP were similar to those found in people without OLP, which can be related to the high exposure of the oral cavity environment to several physical, chemical and microbiological stimuli, important generators of the oxidative stress. Lichen planus Oxidative stress Lipid peroxidation Saliva Vasconcelos, Roseane Carvalho verfasserin aut Lopes, Maria Luiza Diniz de Sousa verfasserin aut Medeiros, Maurília Raquel de Souto verfasserin aut de Araújo, Aurigena Antunes verfasserin aut da Silveira, Éricka Janine Dantas verfasserin aut de Medeiros, Ana Miryam Costa verfasserin aut Enthalten in Pathology, research and practice München : Elsevier, 1978 248 Online-Ressource (DE-627)325789517 (DE-600)2039756-2 (DE-576)094480672 1618-0631 nnns volume:248 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.47 Pathologie Medizin VZ AR 248
allfieldsSound	10.1016/j.prp.2023.154569 doi (DE-627)ELV061526134 (ELSEVIER)S0344-0338(23)00269-8 DE-627 ger DE-627 rda eng 610 VZ 44.47 bkl Gonzaga, Amanda Katarinny Goes verfasserin aut Oxidative stress markers in the saliva of patients with oral lichen planus 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the levels of oxidative stress markers in the saliva of patients with oral lichen planus (OLP).Methods: A cross-sectional study was conducted with 22 patients diagnosed both clinically and histologically with OLP (reticular or erosive) and 12 individuals without OLP. Non-stimulated sialometry was performed and oxidative stress (myeloperoxidase - MPO and malondialdehyde - MDA) and antioxidant (superoxide dismutase - SOD and glutathione - GSH) markers were determined in the saliva.Results: Among the patients with OLP, most were women (n = 19; 86.4%) and reported to have experienced menopause (63.2%). Patients with OLP were mostly in the active stage of the disease (n = 17; 77.3%) and the reticular form was predominant (n = 15; 68.2%). No statistically significant differences were observed when comparing SOD, GSH, MPO and MDA values between individuals with and without OLP, as well as between erosive and reticular forms of OLP (p > 0.05). Patients with inactive OLP presented higher SOD when compared to those with active disease (p = 0.031).Conclusion: Oxidative stress markers in the saliva of patients with OLP were similar to those found in people without OLP, which can be related to the high exposure of the oral cavity environment to several physical, chemical and microbiological stimuli, important generators of the oxidative stress. Lichen planus Oxidative stress Lipid peroxidation Saliva Vasconcelos, Roseane Carvalho verfasserin aut Lopes, Maria Luiza Diniz de Sousa verfasserin aut Medeiros, Maurília Raquel de Souto verfasserin aut de Araújo, Aurigena Antunes verfasserin aut da Silveira, Éricka Janine Dantas verfasserin aut de Medeiros, Ana Miryam Costa verfasserin aut Enthalten in Pathology, research and practice München : Elsevier, 1978 248 Online-Ressource (DE-627)325789517 (DE-600)2039756-2 (DE-576)094480672 1618-0631 nnns volume:248 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.47 Pathologie Medizin VZ AR 248
language	English
source	Enthalten in Pathology, research and practice 248 volume:248
sourceStr	Enthalten in Pathology, research and practice 248 volume:248
format_phy_str_mv	Article
bklname	Pathologie
institution	findex.gbv.de
topic_facet	Lichen planus Oxidative stress Lipid peroxidation Saliva
dewey-raw	610
isfreeaccess_bool	false
container_title	Pathology, research and practice
authorswithroles_txt_mv	Gonzaga, Amanda Katarinny Goes @@aut@@ Vasconcelos, Roseane Carvalho @@aut@@ Lopes, Maria Luiza Diniz de Sousa @@aut@@ Medeiros, Maurília Raquel de Souto @@aut@@ de Araújo, Aurigena Antunes @@aut@@ da Silveira, Éricka Janine Dantas @@aut@@ de Medeiros, Ana Miryam Costa @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	325789517
dewey-sort	3610
id	ELV061526134
language_de	englisch
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Non-stimulated sialometry was performed and oxidative stress (myeloperoxidase - MPO and malondialdehyde - MDA) and antioxidant (superoxide dismutase - SOD and glutathione - GSH) markers were determined in the saliva.Results: Among the patients with OLP, most were women (n = 19; 86.4%) and reported to have experienced menopause (63.2%). Patients with OLP were mostly in the active stage of the disease (n = 17; 77.3%) and the reticular form was predominant (n = 15; 68.2%). No statistically significant differences were observed when comparing SOD, GSH, MPO and MDA values between individuals with and without OLP, as well as between erosive and reticular forms of OLP (p > 0.05). Patients with inactive OLP presented higher SOD when compared to those with active disease (p = 0.031).Conclusion: Oxidative stress markers in the saliva of patients with OLP were similar to those found in people without OLP, which can be related to the high exposure of the oral cavity environment to several physical, chemical and microbiological stimuli, important generators of the oxidative stress.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Lichen planus</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oxidative stress</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Lipid peroxidation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Saliva</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Vasconcelos, Roseane Carvalho</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield 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author	Gonzaga, Amanda Katarinny Goes
spellingShingle	Gonzaga, Amanda Katarinny Goes ddc 610 bkl 44.47 misc Lichen planus misc Oxidative stress misc Lipid peroxidation misc Saliva Oxidative stress markers in the saliva of patients with oral lichen planus
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topic_title	610 VZ 44.47 bkl Oxidative stress markers in the saliva of patients with oral lichen planus Lichen planus Oxidative stress Lipid peroxidation Saliva
topic	ddc 610 bkl 44.47 misc Lichen planus misc Oxidative stress misc Lipid peroxidation misc Saliva
topic_unstemmed	ddc 610 bkl 44.47 misc Lichen planus misc Oxidative stress misc Lipid peroxidation misc Saliva
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title	Oxidative stress markers in the saliva of patients with oral lichen planus
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title_full	Oxidative stress markers in the saliva of patients with oral lichen planus
author_sort	Gonzaga, Amanda Katarinny Goes
journal	Pathology, research and practice
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author_browse	Gonzaga, Amanda Katarinny Goes Vasconcelos, Roseane Carvalho Lopes, Maria Luiza Diniz de Sousa Medeiros, Maurília Raquel de Souto de Araújo, Aurigena Antunes da Silveira, Éricka Janine Dantas de Medeiros, Ana Miryam Costa
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author-letter	Gonzaga, Amanda Katarinny Goes
doi_str_mv	10.1016/j.prp.2023.154569
dewey-full	610
author2-role	verfasserin
title_sort	oxidative stress markers in the saliva of patients with oral lichen planus
title_auth	Oxidative stress markers in the saliva of patients with oral lichen planus
abstract	Objective: To evaluate the levels of oxidative stress markers in the saliva of patients with oral lichen planus (OLP).Methods: A cross-sectional study was conducted with 22 patients diagnosed both clinically and histologically with OLP (reticular or erosive) and 12 individuals without OLP. Non-stimulated sialometry was performed and oxidative stress (myeloperoxidase - MPO and malondialdehyde - MDA) and antioxidant (superoxide dismutase - SOD and glutathione - GSH) markers were determined in the saliva.Results: Among the patients with OLP, most were women (n = 19; 86.4%) and reported to have experienced menopause (63.2%). Patients with OLP were mostly in the active stage of the disease (n = 17; 77.3%) and the reticular form was predominant (n = 15; 68.2%). No statistically significant differences were observed when comparing SOD, GSH, MPO and MDA values between individuals with and without OLP, as well as between erosive and reticular forms of OLP (p > 0.05). Patients with inactive OLP presented higher SOD when compared to those with active disease (p = 0.031).Conclusion: Oxidative stress markers in the saliva of patients with OLP were similar to those found in people without OLP, which can be related to the high exposure of the oral cavity environment to several physical, chemical and microbiological stimuli, important generators of the oxidative stress.
abstractGer	Objective: To evaluate the levels of oxidative stress markers in the saliva of patients with oral lichen planus (OLP).Methods: A cross-sectional study was conducted with 22 patients diagnosed both clinically and histologically with OLP (reticular or erosive) and 12 individuals without OLP. Non-stimulated sialometry was performed and oxidative stress (myeloperoxidase - MPO and malondialdehyde - MDA) and antioxidant (superoxide dismutase - SOD and glutathione - GSH) markers were determined in the saliva.Results: Among the patients with OLP, most were women (n = 19; 86.4%) and reported to have experienced menopause (63.2%). Patients with OLP were mostly in the active stage of the disease (n = 17; 77.3%) and the reticular form was predominant (n = 15; 68.2%). No statistically significant differences were observed when comparing SOD, GSH, MPO and MDA values between individuals with and without OLP, as well as between erosive and reticular forms of OLP (p > 0.05). Patients with inactive OLP presented higher SOD when compared to those with active disease (p = 0.031).Conclusion: Oxidative stress markers in the saliva of patients with OLP were similar to those found in people without OLP, which can be related to the high exposure of the oral cavity environment to several physical, chemical and microbiological stimuli, important generators of the oxidative stress.
abstract_unstemmed	Objective: To evaluate the levels of oxidative stress markers in the saliva of patients with oral lichen planus (OLP).Methods: A cross-sectional study was conducted with 22 patients diagnosed both clinically and histologically with OLP (reticular or erosive) and 12 individuals without OLP. Non-stimulated sialometry was performed and oxidative stress (myeloperoxidase - MPO and malondialdehyde - MDA) and antioxidant (superoxide dismutase - SOD and glutathione - GSH) markers were determined in the saliva.Results: Among the patients with OLP, most were women (n = 19; 86.4%) and reported to have experienced menopause (63.2%). Patients with OLP were mostly in the active stage of the disease (n = 17; 77.3%) and the reticular form was predominant (n = 15; 68.2%). No statistically significant differences were observed when comparing SOD, GSH, MPO and MDA values between individuals with and without OLP, as well as between erosive and reticular forms of OLP (p > 0.05). Patients with inactive OLP presented higher SOD when compared to those with active disease (p = 0.031).Conclusion: Oxidative stress markers in the saliva of patients with OLP were similar to those found in people without OLP, which can be related to the high exposure of the oral cavity environment to several physical, chemical and microbiological stimuli, important generators of the oxidative stress.
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title_short	Oxidative stress markers in the saliva of patients with oral lichen planus
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author2	Vasconcelos, Roseane Carvalho Lopes, Maria Luiza Diniz de Sousa Medeiros, Maurília Raquel de Souto de Araújo, Aurigena Antunes da Silveira, Éricka Janine Dantas de Medeiros, Ana Miryam Costa
author2Str	Vasconcelos, Roseane Carvalho Lopes, Maria Luiza Diniz de Sousa Medeiros, Maurília Raquel de Souto de Araújo, Aurigena Antunes da Silveira, Éricka Janine Dantas de Medeiros, Ana Miryam Costa
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up_date	2024-07-06T17:45:56.466Z
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Oxidative stress markers in the saliva of patients with oral lichen planus

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