Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma
Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Rahimian, Neda [verfasserIn] Sheida, Amirhossein [verfasserIn] Rajabi, Mohammadreza [verfasserIn] Heidari, Mohammad Mahdi [verfasserIn] Tobeiha, Mohammad [verfasserIn] Esfahani, Pegah Veradi [verfasserIn] Ahmadi Asouri, Sahar [verfasserIn] Hamblin, Michael R. [verfasserIn] Mohamadzadeh, Omid [verfasserIn] Motamedzadeh, Alireza [verfasserIn] Khaksary Mahabady, Mahmood [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2023 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Pathology, research and practice - München : Elsevier, 1978, 248 |
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| Übergeordnetes Werk: |
volume:248 |
| DOI / URN: |
10.1016/j.prp.2023.154649 |
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| Katalog-ID: |
ELV061527394 |
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| 520 | |a Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention is ineffective. Earlier identification of PA could reduce morbidity and allow better clinical management of the affected patients. Non-coding RNAs (ncRNAs) do not generally code for proteins, but can modulate biological processes at the post-transcriptional level through a variety of molecular mechanisms. An increased number of ncRNA expression profiles have been found in PAs. Therefore, understanding the expression patterns of different ncRNAs could be a promising method for developing non-invasive biomarkers. This review summarizes the expression patterns of dysregulated ncRNAs (microRNAs, long non-coding RNAs, and circular RNAs) involved in PA, which could one day serve as innovative biomarkers or therapeutic targets for the treatment of this neoplasia. We also discuss the potential molecular pathways by which the dysregulated ncRNAs could cause PA and affect its progression. | ||
| 650 | 4 | |a Pituitary adenomas | |
| 650 | 4 | |a Non-coding RNAs | |
| 650 | 4 | |a Exosomes | |
| 650 | 4 | |a MicroRNAs | |
| 650 | 4 | |a Long non-coding RNAs | |
| 650 | 4 | |a Circular RNAs | |
| 700 | 1 | |a Sheida, Amirhossein |e verfasserin |4 aut | |
| 700 | 1 | |a Rajabi, Mohammadreza |e verfasserin |4 aut | |
| 700 | 1 | |a Heidari, Mohammad Mahdi |e verfasserin |4 aut | |
| 700 | 1 | |a Tobeiha, Mohammad |e verfasserin |4 aut | |
| 700 | 1 | |a Esfahani, Pegah Veradi |e verfasserin |4 aut | |
| 700 | 1 | |a Ahmadi Asouri, Sahar |e verfasserin |4 aut | |
| 700 | 1 | |a Hamblin, Michael R. |e verfasserin |4 aut | |
| 700 | 1 | |a Mohamadzadeh, Omid |e verfasserin |4 aut | |
| 700 | 1 | |a Motamedzadeh, Alireza |e verfasserin |4 aut | |
| 700 | 1 | |a Khaksary Mahabady, Mahmood |e verfasserin |4 aut | |
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2023 |
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44.47 |
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2023 |
| allfields |
10.1016/j.prp.2023.154649 doi (DE-627)ELV061527394 (ELSEVIER)S0344-0338(23)00349-7 DE-627 ger DE-627 rda eng 610 VZ 44.47 bkl Rahimian, Neda verfasserin aut Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention is ineffective. Earlier identification of PA could reduce morbidity and allow better clinical management of the affected patients. Non-coding RNAs (ncRNAs) do not generally code for proteins, but can modulate biological processes at the post-transcriptional level through a variety of molecular mechanisms. An increased number of ncRNA expression profiles have been found in PAs. Therefore, understanding the expression patterns of different ncRNAs could be a promising method for developing non-invasive biomarkers. This review summarizes the expression patterns of dysregulated ncRNAs (microRNAs, long non-coding RNAs, and circular RNAs) involved in PA, which could one day serve as innovative biomarkers or therapeutic targets for the treatment of this neoplasia. We also discuss the potential molecular pathways by which the dysregulated ncRNAs could cause PA and affect its progression. Pituitary adenomas Non-coding RNAs Exosomes MicroRNAs Long non-coding RNAs Circular RNAs Sheida, Amirhossein verfasserin aut Rajabi, Mohammadreza verfasserin aut Heidari, Mohammad Mahdi verfasserin aut Tobeiha, Mohammad verfasserin aut Esfahani, Pegah Veradi verfasserin aut Ahmadi Asouri, Sahar verfasserin aut Hamblin, Michael R. verfasserin aut Mohamadzadeh, Omid verfasserin aut Motamedzadeh, Alireza verfasserin aut Khaksary Mahabady, Mahmood verfasserin aut Enthalten in Pathology, research and practice München : Elsevier, 1978 248 Online-Ressource (DE-627)325789517 (DE-600)2039756-2 (DE-576)094480672 1618-0631 nnns volume:248 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.47 Pathologie Medizin VZ AR 248 |
| spelling |
10.1016/j.prp.2023.154649 doi (DE-627)ELV061527394 (ELSEVIER)S0344-0338(23)00349-7 DE-627 ger DE-627 rda eng 610 VZ 44.47 bkl Rahimian, Neda verfasserin aut Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention is ineffective. Earlier identification of PA could reduce morbidity and allow better clinical management of the affected patients. Non-coding RNAs (ncRNAs) do not generally code for proteins, but can modulate biological processes at the post-transcriptional level through a variety of molecular mechanisms. An increased number of ncRNA expression profiles have been found in PAs. Therefore, understanding the expression patterns of different ncRNAs could be a promising method for developing non-invasive biomarkers. This review summarizes the expression patterns of dysregulated ncRNAs (microRNAs, long non-coding RNAs, and circular RNAs) involved in PA, which could one day serve as innovative biomarkers or therapeutic targets for the treatment of this neoplasia. We also discuss the potential molecular pathways by which the dysregulated ncRNAs could cause PA and affect its progression. Pituitary adenomas Non-coding RNAs Exosomes MicroRNAs Long non-coding RNAs Circular RNAs Sheida, Amirhossein verfasserin aut Rajabi, Mohammadreza verfasserin aut Heidari, Mohammad Mahdi verfasserin aut Tobeiha, Mohammad verfasserin aut Esfahani, Pegah Veradi verfasserin aut Ahmadi Asouri, Sahar verfasserin aut Hamblin, Michael R. verfasserin aut Mohamadzadeh, Omid verfasserin aut Motamedzadeh, Alireza verfasserin aut Khaksary Mahabady, Mahmood verfasserin aut Enthalten in Pathology, research and practice München : Elsevier, 1978 248 Online-Ressource (DE-627)325789517 (DE-600)2039756-2 (DE-576)094480672 1618-0631 nnns volume:248 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.47 Pathologie Medizin VZ AR 248 |
| allfields_unstemmed |
10.1016/j.prp.2023.154649 doi (DE-627)ELV061527394 (ELSEVIER)S0344-0338(23)00349-7 DE-627 ger DE-627 rda eng 610 VZ 44.47 bkl Rahimian, Neda verfasserin aut Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention is ineffective. Earlier identification of PA could reduce morbidity and allow better clinical management of the affected patients. Non-coding RNAs (ncRNAs) do not generally code for proteins, but can modulate biological processes at the post-transcriptional level through a variety of molecular mechanisms. An increased number of ncRNA expression profiles have been found in PAs. Therefore, understanding the expression patterns of different ncRNAs could be a promising method for developing non-invasive biomarkers. This review summarizes the expression patterns of dysregulated ncRNAs (microRNAs, long non-coding RNAs, and circular RNAs) involved in PA, which could one day serve as innovative biomarkers or therapeutic targets for the treatment of this neoplasia. We also discuss the potential molecular pathways by which the dysregulated ncRNAs could cause PA and affect its progression. Pituitary adenomas Non-coding RNAs Exosomes MicroRNAs Long non-coding RNAs Circular RNAs Sheida, Amirhossein verfasserin aut Rajabi, Mohammadreza verfasserin aut Heidari, Mohammad Mahdi verfasserin aut Tobeiha, Mohammad verfasserin aut Esfahani, Pegah Veradi verfasserin aut Ahmadi Asouri, Sahar verfasserin aut Hamblin, Michael R. verfasserin aut Mohamadzadeh, Omid verfasserin aut Motamedzadeh, Alireza verfasserin aut Khaksary Mahabady, Mahmood verfasserin aut Enthalten in Pathology, research and practice München : Elsevier, 1978 248 Online-Ressource (DE-627)325789517 (DE-600)2039756-2 (DE-576)094480672 1618-0631 nnns volume:248 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.47 Pathologie Medizin VZ AR 248 |
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10.1016/j.prp.2023.154649 doi (DE-627)ELV061527394 (ELSEVIER)S0344-0338(23)00349-7 DE-627 ger DE-627 rda eng 610 VZ 44.47 bkl Rahimian, Neda verfasserin aut Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention is ineffective. Earlier identification of PA could reduce morbidity and allow better clinical management of the affected patients. Non-coding RNAs (ncRNAs) do not generally code for proteins, but can modulate biological processes at the post-transcriptional level through a variety of molecular mechanisms. An increased number of ncRNA expression profiles have been found in PAs. Therefore, understanding the expression patterns of different ncRNAs could be a promising method for developing non-invasive biomarkers. This review summarizes the expression patterns of dysregulated ncRNAs (microRNAs, long non-coding RNAs, and circular RNAs) involved in PA, which could one day serve as innovative biomarkers or therapeutic targets for the treatment of this neoplasia. We also discuss the potential molecular pathways by which the dysregulated ncRNAs could cause PA and affect its progression. Pituitary adenomas Non-coding RNAs Exosomes MicroRNAs Long non-coding RNAs Circular RNAs Sheida, Amirhossein verfasserin aut Rajabi, Mohammadreza verfasserin aut Heidari, Mohammad Mahdi verfasserin aut Tobeiha, Mohammad verfasserin aut Esfahani, Pegah Veradi verfasserin aut Ahmadi Asouri, Sahar verfasserin aut Hamblin, Michael R. verfasserin aut Mohamadzadeh, Omid verfasserin aut Motamedzadeh, Alireza verfasserin aut Khaksary Mahabady, Mahmood verfasserin aut Enthalten in Pathology, research and practice München : Elsevier, 1978 248 Online-Ressource (DE-627)325789517 (DE-600)2039756-2 (DE-576)094480672 1618-0631 nnns volume:248 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.47 Pathologie Medizin VZ AR 248 |
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10.1016/j.prp.2023.154649 doi (DE-627)ELV061527394 (ELSEVIER)S0344-0338(23)00349-7 DE-627 ger DE-627 rda eng 610 VZ 44.47 bkl Rahimian, Neda verfasserin aut Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention is ineffective. Earlier identification of PA could reduce morbidity and allow better clinical management of the affected patients. Non-coding RNAs (ncRNAs) do not generally code for proteins, but can modulate biological processes at the post-transcriptional level through a variety of molecular mechanisms. An increased number of ncRNA expression profiles have been found in PAs. Therefore, understanding the expression patterns of different ncRNAs could be a promising method for developing non-invasive biomarkers. This review summarizes the expression patterns of dysregulated ncRNAs (microRNAs, long non-coding RNAs, and circular RNAs) involved in PA, which could one day serve as innovative biomarkers or therapeutic targets for the treatment of this neoplasia. We also discuss the potential molecular pathways by which the dysregulated ncRNAs could cause PA and affect its progression. Pituitary adenomas Non-coding RNAs Exosomes MicroRNAs Long non-coding RNAs Circular RNAs Sheida, Amirhossein verfasserin aut Rajabi, Mohammadreza verfasserin aut Heidari, Mohammad Mahdi verfasserin aut Tobeiha, Mohammad verfasserin aut Esfahani, Pegah Veradi verfasserin aut Ahmadi Asouri, Sahar verfasserin aut Hamblin, Michael R. verfasserin aut Mohamadzadeh, Omid verfasserin aut Motamedzadeh, Alireza verfasserin aut Khaksary Mahabady, Mahmood verfasserin aut Enthalten in Pathology, research and practice München : Elsevier, 1978 248 Online-Ressource (DE-627)325789517 (DE-600)2039756-2 (DE-576)094480672 1618-0631 nnns volume:248 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.47 Pathologie Medizin VZ AR 248 |
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Enthalten in Pathology, research and practice 248 volume:248 |
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Rahimian, Neda @@aut@@ Sheida, Amirhossein @@aut@@ Rajabi, Mohammadreza @@aut@@ Heidari, Mohammad Mahdi @@aut@@ Tobeiha, Mohammad @@aut@@ Esfahani, Pegah Veradi @@aut@@ Ahmadi Asouri, Sahar @@aut@@ Hamblin, Michael R. @@aut@@ Mohamadzadeh, Omid @@aut@@ Motamedzadeh, Alireza @@aut@@ Khaksary Mahabady, Mahmood @@aut@@ |
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2023-01-01T00:00:00Z |
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Rahimian, Neda |
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610 VZ 44.47 bkl Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma Pituitary adenomas Non-coding RNAs Exosomes MicroRNAs Long non-coding RNAs Circular RNAs |
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Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma |
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Rahimian, Neda Sheida, Amirhossein Rajabi, Mohammadreza Heidari, Mohammad Mahdi Tobeiha, Mohammad Esfahani, Pegah Veradi Ahmadi Asouri, Sahar Hamblin, Michael R. Mohamadzadeh, Omid Motamedzadeh, Alireza Khaksary Mahabady, Mahmood |
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non-coding rnas and exosomal non-coding rnas in pituitary adenoma |
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Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma |
| abstract |
Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention is ineffective. Earlier identification of PA could reduce morbidity and allow better clinical management of the affected patients. Non-coding RNAs (ncRNAs) do not generally code for proteins, but can modulate biological processes at the post-transcriptional level through a variety of molecular mechanisms. An increased number of ncRNA expression profiles have been found in PAs. Therefore, understanding the expression patterns of different ncRNAs could be a promising method for developing non-invasive biomarkers. This review summarizes the expression patterns of dysregulated ncRNAs (microRNAs, long non-coding RNAs, and circular RNAs) involved in PA, which could one day serve as innovative biomarkers or therapeutic targets for the treatment of this neoplasia. We also discuss the potential molecular pathways by which the dysregulated ncRNAs could cause PA and affect its progression. |
| abstractGer |
Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention is ineffective. Earlier identification of PA could reduce morbidity and allow better clinical management of the affected patients. Non-coding RNAs (ncRNAs) do not generally code for proteins, but can modulate biological processes at the post-transcriptional level through a variety of molecular mechanisms. An increased number of ncRNA expression profiles have been found in PAs. Therefore, understanding the expression patterns of different ncRNAs could be a promising method for developing non-invasive biomarkers. This review summarizes the expression patterns of dysregulated ncRNAs (microRNAs, long non-coding RNAs, and circular RNAs) involved in PA, which could one day serve as innovative biomarkers or therapeutic targets for the treatment of this neoplasia. We also discuss the potential molecular pathways by which the dysregulated ncRNAs could cause PA and affect its progression. |
| abstract_unstemmed |
Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention is ineffective. Earlier identification of PA could reduce morbidity and allow better clinical management of the affected patients. Non-coding RNAs (ncRNAs) do not generally code for proteins, but can modulate biological processes at the post-transcriptional level through a variety of molecular mechanisms. An increased number of ncRNA expression profiles have been found in PAs. Therefore, understanding the expression patterns of different ncRNAs could be a promising method for developing non-invasive biomarkers. This review summarizes the expression patterns of dysregulated ncRNAs (microRNAs, long non-coding RNAs, and circular RNAs) involved in PA, which could one day serve as innovative biomarkers or therapeutic targets for the treatment of this neoplasia. We also discuss the potential molecular pathways by which the dysregulated ncRNAs could cause PA and affect its progression. |
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Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma |
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Sheida, Amirhossein Rajabi, Mohammadreza Heidari, Mohammad Mahdi Tobeiha, Mohammad Esfahani, Pegah Veradi Ahmadi Asouri, Sahar Hamblin, Michael R. Mohamadzadeh, Omid Motamedzadeh, Alireza Khaksary Mahabady, Mahmood |
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|
| score |
7.399768 |