Tricks of the trade: Techniques for preoperative localization in reoperative parathyroidectomy
Background: Reoperative parathyroidectomy for recurrent/persistent primary hyperparathyroidism (PHPT) has high rates of failure. The goal of this study was to analyze our experience with imaging and parathyroid vein sampling (PAVS) for recurrent/persistent PHPT.Methods: We performed a retrospective...
Ausführliche Beschreibung
Autor*in: |
Amjad, Wajid [verfasserIn] Trerotola, Scott O. [verfasserIn] Fraker, Douglas L. [verfasserIn] Wachtel, Heather [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2023 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: The American journal of surgery - Amsterdam [u.a.] : Elsevier Science, 1926, 226, Seite 207-212 |
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Übergeordnetes Werk: |
volume:226 ; pages:207-212 |
DOI / URN: |
10.1016/j.amjsurg.2023.04.005 |
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Katalog-ID: |
ELV062397362 |
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245 | 1 | 0 | |a Tricks of the trade: Techniques for preoperative localization in reoperative parathyroidectomy |
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520 | |a Background: Reoperative parathyroidectomy for recurrent/persistent primary hyperparathyroidism (PHPT) has high rates of failure. The goal of this study was to analyze our experience with imaging and parathyroid vein sampling (PAVS) for recurrent/persistent PHPT.Methods: We performed a retrospective cohort study (2002–2018) of patients with recurrent/persistent PHPT undergoing reoperative parathyroidectomy.Results: Among 181 patients, the most common imaging study was sestamibi (89.5%), followed by ultrasound (75.7%). CT had the highest rate of localization (70.8%) compared to sestamibi (58.0%) and ultrasound (47.4%). PAVS was performed in 25 patients, and localized in 96%. Ultrasound and sestamibi both demonstrated 62% PPV for operative pathology, compared to 41% in CT. PAVS was 95% sensitive with 95% PPV for predicting the correct side of abnormal parathyroid tissue.Conclusions: We recommend a sequential imaging evaluation for reoperative parathyroidectomy, with sestamibi and/or ultrasound followed by CT. PAVS should be considered if non-invasive imaging fails to localize. | ||
650 | 4 | |a Reoperative parathyroidectomy | |
650 | 4 | |a Parathyroidectomy | |
650 | 4 | |a Jugular venous sampling | |
650 | 4 | |a Primary hyperparathyroidism | |
650 | 4 | |a Recurrent primary hyperparathyroidism | |
650 | 4 | |a Parathyroid venous sampling | |
700 | 1 | |a Trerotola, Scott O. |e verfasserin |4 aut | |
700 | 1 | |a Fraker, Douglas L. |e verfasserin |4 aut | |
700 | 1 | |a Wachtel, Heather |e verfasserin |0 (orcid)0000-0003-3786-3638 |4 aut | |
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773 | 1 | 8 | |g volume:226 |g pages:207-212 |
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10.1016/j.amjsurg.2023.04.005 doi (DE-627)ELV062397362 (ELSEVIER)S0002-9610(23)00151-4 DE-627 ger DE-627 rda eng 610 VZ 44.65 bkl 44.65 bkl Amjad, Wajid verfasserin (orcid)0000-0003-0815-5843 aut Tricks of the trade: Techniques for preoperative localization in reoperative parathyroidectomy 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Reoperative parathyroidectomy for recurrent/persistent primary hyperparathyroidism (PHPT) has high rates of failure. The goal of this study was to analyze our experience with imaging and parathyroid vein sampling (PAVS) for recurrent/persistent PHPT.Methods: We performed a retrospective cohort study (2002–2018) of patients with recurrent/persistent PHPT undergoing reoperative parathyroidectomy.Results: Among 181 patients, the most common imaging study was sestamibi (89.5%), followed by ultrasound (75.7%). CT had the highest rate of localization (70.8%) compared to sestamibi (58.0%) and ultrasound (47.4%). PAVS was performed in 25 patients, and localized in 96%. Ultrasound and sestamibi both demonstrated 62% PPV for operative pathology, compared to 41% in CT. PAVS was 95% sensitive with 95% PPV for predicting the correct side of abnormal parathyroid tissue.Conclusions: We recommend a sequential imaging evaluation for reoperative parathyroidectomy, with sestamibi and/or ultrasound followed by CT. PAVS should be considered if non-invasive imaging fails to localize. Reoperative parathyroidectomy Parathyroidectomy Jugular venous sampling Primary hyperparathyroidism Recurrent primary hyperparathyroidism Parathyroid venous sampling Trerotola, Scott O. verfasserin aut Fraker, Douglas L. verfasserin aut Wachtel, Heather verfasserin (orcid)0000-0003-3786-3638 aut Enthalten in The American journal of surgery Amsterdam [u.a.] : Elsevier Science, 1926 226, Seite 207-212 Online-Ressource (DE-627)320427757 (DE-600)2003374-6 (DE-576)121465497 1879-1883 nnns volume:226 pages:207-212 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 Chirurgie VZ 44.65 Chirurgie VZ AR 226 207-212 |
spelling |
10.1016/j.amjsurg.2023.04.005 doi (DE-627)ELV062397362 (ELSEVIER)S0002-9610(23)00151-4 DE-627 ger DE-627 rda eng 610 VZ 44.65 bkl 44.65 bkl Amjad, Wajid verfasserin (orcid)0000-0003-0815-5843 aut Tricks of the trade: Techniques for preoperative localization in reoperative parathyroidectomy 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Reoperative parathyroidectomy for recurrent/persistent primary hyperparathyroidism (PHPT) has high rates of failure. The goal of this study was to analyze our experience with imaging and parathyroid vein sampling (PAVS) for recurrent/persistent PHPT.Methods: We performed a retrospective cohort study (2002–2018) of patients with recurrent/persistent PHPT undergoing reoperative parathyroidectomy.Results: Among 181 patients, the most common imaging study was sestamibi (89.5%), followed by ultrasound (75.7%). CT had the highest rate of localization (70.8%) compared to sestamibi (58.0%) and ultrasound (47.4%). PAVS was performed in 25 patients, and localized in 96%. Ultrasound and sestamibi both demonstrated 62% PPV for operative pathology, compared to 41% in CT. PAVS was 95% sensitive with 95% PPV for predicting the correct side of abnormal parathyroid tissue.Conclusions: We recommend a sequential imaging evaluation for reoperative parathyroidectomy, with sestamibi and/or ultrasound followed by CT. PAVS should be considered if non-invasive imaging fails to localize. Reoperative parathyroidectomy Parathyroidectomy Jugular venous sampling Primary hyperparathyroidism Recurrent primary hyperparathyroidism Parathyroid venous sampling Trerotola, Scott O. verfasserin aut Fraker, Douglas L. verfasserin aut Wachtel, Heather verfasserin (orcid)0000-0003-3786-3638 aut Enthalten in The American journal of surgery Amsterdam [u.a.] : Elsevier Science, 1926 226, Seite 207-212 Online-Ressource (DE-627)320427757 (DE-600)2003374-6 (DE-576)121465497 1879-1883 nnns volume:226 pages:207-212 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 Chirurgie VZ 44.65 Chirurgie VZ AR 226 207-212 |
allfields_unstemmed |
10.1016/j.amjsurg.2023.04.005 doi (DE-627)ELV062397362 (ELSEVIER)S0002-9610(23)00151-4 DE-627 ger DE-627 rda eng 610 VZ 44.65 bkl 44.65 bkl Amjad, Wajid verfasserin (orcid)0000-0003-0815-5843 aut Tricks of the trade: Techniques for preoperative localization in reoperative parathyroidectomy 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Reoperative parathyroidectomy for recurrent/persistent primary hyperparathyroidism (PHPT) has high rates of failure. The goal of this study was to analyze our experience with imaging and parathyroid vein sampling (PAVS) for recurrent/persistent PHPT.Methods: We performed a retrospective cohort study (2002–2018) of patients with recurrent/persistent PHPT undergoing reoperative parathyroidectomy.Results: Among 181 patients, the most common imaging study was sestamibi (89.5%), followed by ultrasound (75.7%). CT had the highest rate of localization (70.8%) compared to sestamibi (58.0%) and ultrasound (47.4%). PAVS was performed in 25 patients, and localized in 96%. Ultrasound and sestamibi both demonstrated 62% PPV for operative pathology, compared to 41% in CT. PAVS was 95% sensitive with 95% PPV for predicting the correct side of abnormal parathyroid tissue.Conclusions: We recommend a sequential imaging evaluation for reoperative parathyroidectomy, with sestamibi and/or ultrasound followed by CT. PAVS should be considered if non-invasive imaging fails to localize. Reoperative parathyroidectomy Parathyroidectomy Jugular venous sampling Primary hyperparathyroidism Recurrent primary hyperparathyroidism Parathyroid venous sampling Trerotola, Scott O. verfasserin aut Fraker, Douglas L. verfasserin aut Wachtel, Heather verfasserin (orcid)0000-0003-3786-3638 aut Enthalten in The American journal of surgery Amsterdam [u.a.] : Elsevier Science, 1926 226, Seite 207-212 Online-Ressource (DE-627)320427757 (DE-600)2003374-6 (DE-576)121465497 1879-1883 nnns volume:226 pages:207-212 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 Chirurgie VZ 44.65 Chirurgie VZ AR 226 207-212 |
allfieldsGer |
10.1016/j.amjsurg.2023.04.005 doi (DE-627)ELV062397362 (ELSEVIER)S0002-9610(23)00151-4 DE-627 ger DE-627 rda eng 610 VZ 44.65 bkl 44.65 bkl Amjad, Wajid verfasserin (orcid)0000-0003-0815-5843 aut Tricks of the trade: Techniques for preoperative localization in reoperative parathyroidectomy 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Reoperative parathyroidectomy for recurrent/persistent primary hyperparathyroidism (PHPT) has high rates of failure. The goal of this study was to analyze our experience with imaging and parathyroid vein sampling (PAVS) for recurrent/persistent PHPT.Methods: We performed a retrospective cohort study (2002–2018) of patients with recurrent/persistent PHPT undergoing reoperative parathyroidectomy.Results: Among 181 patients, the most common imaging study was sestamibi (89.5%), followed by ultrasound (75.7%). CT had the highest rate of localization (70.8%) compared to sestamibi (58.0%) and ultrasound (47.4%). PAVS was performed in 25 patients, and localized in 96%. Ultrasound and sestamibi both demonstrated 62% PPV for operative pathology, compared to 41% in CT. PAVS was 95% sensitive with 95% PPV for predicting the correct side of abnormal parathyroid tissue.Conclusions: We recommend a sequential imaging evaluation for reoperative parathyroidectomy, with sestamibi and/or ultrasound followed by CT. PAVS should be considered if non-invasive imaging fails to localize. Reoperative parathyroidectomy Parathyroidectomy Jugular venous sampling Primary hyperparathyroidism Recurrent primary hyperparathyroidism Parathyroid venous sampling Trerotola, Scott O. verfasserin aut Fraker, Douglas L. verfasserin aut Wachtel, Heather verfasserin (orcid)0000-0003-3786-3638 aut Enthalten in The American journal of surgery Amsterdam [u.a.] : Elsevier Science, 1926 226, Seite 207-212 Online-Ressource (DE-627)320427757 (DE-600)2003374-6 (DE-576)121465497 1879-1883 nnns volume:226 pages:207-212 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 Chirurgie VZ 44.65 Chirurgie VZ AR 226 207-212 |
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10.1016/j.amjsurg.2023.04.005 doi (DE-627)ELV062397362 (ELSEVIER)S0002-9610(23)00151-4 DE-627 ger DE-627 rda eng 610 VZ 44.65 bkl 44.65 bkl Amjad, Wajid verfasserin (orcid)0000-0003-0815-5843 aut Tricks of the trade: Techniques for preoperative localization in reoperative parathyroidectomy 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Reoperative parathyroidectomy for recurrent/persistent primary hyperparathyroidism (PHPT) has high rates of failure. The goal of this study was to analyze our experience with imaging and parathyroid vein sampling (PAVS) for recurrent/persistent PHPT.Methods: We performed a retrospective cohort study (2002–2018) of patients with recurrent/persistent PHPT undergoing reoperative parathyroidectomy.Results: Among 181 patients, the most common imaging study was sestamibi (89.5%), followed by ultrasound (75.7%). CT had the highest rate of localization (70.8%) compared to sestamibi (58.0%) and ultrasound (47.4%). PAVS was performed in 25 patients, and localized in 96%. Ultrasound and sestamibi both demonstrated 62% PPV for operative pathology, compared to 41% in CT. PAVS was 95% sensitive with 95% PPV for predicting the correct side of abnormal parathyroid tissue.Conclusions: We recommend a sequential imaging evaluation for reoperative parathyroidectomy, with sestamibi and/or ultrasound followed by CT. PAVS should be considered if non-invasive imaging fails to localize. Reoperative parathyroidectomy Parathyroidectomy Jugular venous sampling Primary hyperparathyroidism Recurrent primary hyperparathyroidism Parathyroid venous sampling Trerotola, Scott O. verfasserin aut Fraker, Douglas L. verfasserin aut Wachtel, Heather verfasserin (orcid)0000-0003-3786-3638 aut Enthalten in The American journal of surgery Amsterdam [u.a.] : Elsevier Science, 1926 226, Seite 207-212 Online-Ressource (DE-627)320427757 (DE-600)2003374-6 (DE-576)121465497 1879-1883 nnns volume:226 pages:207-212 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 Chirurgie VZ 44.65 Chirurgie VZ AR 226 207-212 |
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Enthalten in The American journal of surgery 226, Seite 207-212 volume:226 pages:207-212 |
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Reoperative parathyroidectomy Parathyroidectomy Jugular venous sampling Primary hyperparathyroidism Recurrent primary hyperparathyroidism Parathyroid venous sampling |
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Amjad, Wajid @@aut@@ Trerotola, Scott O. @@aut@@ Fraker, Douglas L. @@aut@@ Wachtel, Heather @@aut@@ |
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2023-01-01T00:00:00Z |
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Amjad, Wajid |
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Amjad, Wajid ddc 610 bkl 44.65 misc Reoperative parathyroidectomy misc Parathyroidectomy misc Jugular venous sampling misc Primary hyperparathyroidism misc Recurrent primary hyperparathyroidism misc Parathyroid venous sampling Tricks of the trade: Techniques for preoperative localization in reoperative parathyroidectomy |
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610 VZ 44.65 bkl Tricks of the trade: Techniques for preoperative localization in reoperative parathyroidectomy Reoperative parathyroidectomy Parathyroidectomy Jugular venous sampling Primary hyperparathyroidism Recurrent primary hyperparathyroidism Parathyroid venous sampling |
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tricks of the trade: techniques for preoperative localization in reoperative parathyroidectomy |
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Tricks of the trade: Techniques for preoperative localization in reoperative parathyroidectomy |
abstract |
Background: Reoperative parathyroidectomy for recurrent/persistent primary hyperparathyroidism (PHPT) has high rates of failure. The goal of this study was to analyze our experience with imaging and parathyroid vein sampling (PAVS) for recurrent/persistent PHPT.Methods: We performed a retrospective cohort study (2002–2018) of patients with recurrent/persistent PHPT undergoing reoperative parathyroidectomy.Results: Among 181 patients, the most common imaging study was sestamibi (89.5%), followed by ultrasound (75.7%). CT had the highest rate of localization (70.8%) compared to sestamibi (58.0%) and ultrasound (47.4%). PAVS was performed in 25 patients, and localized in 96%. Ultrasound and sestamibi both demonstrated 62% PPV for operative pathology, compared to 41% in CT. PAVS was 95% sensitive with 95% PPV for predicting the correct side of abnormal parathyroid tissue.Conclusions: We recommend a sequential imaging evaluation for reoperative parathyroidectomy, with sestamibi and/or ultrasound followed by CT. PAVS should be considered if non-invasive imaging fails to localize. |
abstractGer |
Background: Reoperative parathyroidectomy for recurrent/persistent primary hyperparathyroidism (PHPT) has high rates of failure. The goal of this study was to analyze our experience with imaging and parathyroid vein sampling (PAVS) for recurrent/persistent PHPT.Methods: We performed a retrospective cohort study (2002–2018) of patients with recurrent/persistent PHPT undergoing reoperative parathyroidectomy.Results: Among 181 patients, the most common imaging study was sestamibi (89.5%), followed by ultrasound (75.7%). CT had the highest rate of localization (70.8%) compared to sestamibi (58.0%) and ultrasound (47.4%). PAVS was performed in 25 patients, and localized in 96%. Ultrasound and sestamibi both demonstrated 62% PPV for operative pathology, compared to 41% in CT. PAVS was 95% sensitive with 95% PPV for predicting the correct side of abnormal parathyroid tissue.Conclusions: We recommend a sequential imaging evaluation for reoperative parathyroidectomy, with sestamibi and/or ultrasound followed by CT. PAVS should be considered if non-invasive imaging fails to localize. |
abstract_unstemmed |
Background: Reoperative parathyroidectomy for recurrent/persistent primary hyperparathyroidism (PHPT) has high rates of failure. The goal of this study was to analyze our experience with imaging and parathyroid vein sampling (PAVS) for recurrent/persistent PHPT.Methods: We performed a retrospective cohort study (2002–2018) of patients with recurrent/persistent PHPT undergoing reoperative parathyroidectomy.Results: Among 181 patients, the most common imaging study was sestamibi (89.5%), followed by ultrasound (75.7%). CT had the highest rate of localization (70.8%) compared to sestamibi (58.0%) and ultrasound (47.4%). PAVS was performed in 25 patients, and localized in 96%. Ultrasound and sestamibi both demonstrated 62% PPV for operative pathology, compared to 41% in CT. PAVS was 95% sensitive with 95% PPV for predicting the correct side of abnormal parathyroid tissue.Conclusions: We recommend a sequential imaging evaluation for reoperative parathyroidectomy, with sestamibi and/or ultrasound followed by CT. PAVS should be considered if non-invasive imaging fails to localize. |
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