Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream (

Red seabream (Pagrus major) is widely consumed in East Asia. As nuclear wastewater is discharged into Japanese waterbodies, the country of origin of marine products must be accurately labeled. Here, we aimed to discover candidate metabolite biomarkers to discriminate between Korean and Japanese red...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Yang, Junho [verfasserIn] Shin, Jiyoung [verfasserIn] Kim, Hyunsuk [verfasserIn] Sim, Yikang [verfasserIn] Yang, Jiyoung [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Biomarker Metabolomics Chemometrics Liquid chromatography-mass spectrometry Origin discrimination Red seabream

Übergeordnetes Werk:	Enthalten in: Food chemistry - New York, NY [u.a.] : Elsevier, 1976, 431
Übergeordnetes Werk:	volume:431

DOI / URN:	10.1016/j.foodchem.2023.137129

Katalog-ID:	ELV062630466

Internformat


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520			\|a Red seabream (Pagrus major) is widely consumed in East Asia. As nuclear wastewater is discharged into Japanese waterbodies, the country of origin of marine products must be accurately labeled. Here, we aimed to discover candidate metabolite biomarkers to discriminate between Korean and Japanese red seabream using LC-Orbitrap mass spectrometry. In total, 95 and 138 putative metabolites were detected via chromatographic separation of fish sampled in the warm and cold seasons, respectively. The spectrometric and chromatographic data were analyzed using principal component analysis and orthogonal partial least squares discriminant analysis. We identified 12 and 19 influential metabolites to discriminate between each origin fish in the warm and cold seasons, respectively, using variable importance in projection scores and p values. Anserine was further selected as a candidate biomarker based on receiver operating characteristic curve analysis. This study provides a basis for using anserine to determine the geographic origin of red seabream.
650		4	\|a Biomarker
650		4	\|a Metabolomics
650		4	\|a Chemometrics
650		4	\|a Liquid chromatography-mass spectrometry
650		4	\|a Origin discrimination
650		4	\|a Red seabream
700	1		\|a Shin, Jiyoung \|e verfasserin \|4 aut
700	1		\|a Kim, Hyunsuk \|e verfasserin \|4 aut
700	1		\|a Sim, Yikang \|e verfasserin \|0 (orcid)0000-0002-0183-9639 \|4 aut
700	1		\|a Yang, Jiyoung \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Food chemistry \|d New York, NY [u.a.] : Elsevier, 1976 \|g 431 \|h Online-Ressource \|w (DE-627)300898509 \|w (DE-600)1483647-6 \|w (DE-576)098330225 \|x 1873-7072 \|7 nnns
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912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2056
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author_variant	j y jy j s js h k hk y s ys j y jy
matchkey_str	article:18737072:2023----::icvrocniaeimresoiciiaeewekra
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publishDate	2023
allfields	10.1016/j.foodchem.2023.137129 doi (DE-627)ELV062630466 (ELSEVIER)S0308-8146(23)01747-8 DE-627 ger DE-627 rda eng 540 660 VZ 58.34 bkl Yang, Junho verfasserin aut Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream ( 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Red seabream (Pagrus major) is widely consumed in East Asia. As nuclear wastewater is discharged into Japanese waterbodies, the country of origin of marine products must be accurately labeled. Here, we aimed to discover candidate metabolite biomarkers to discriminate between Korean and Japanese red seabream using LC-Orbitrap mass spectrometry. In total, 95 and 138 putative metabolites were detected via chromatographic separation of fish sampled in the warm and cold seasons, respectively. The spectrometric and chromatographic data were analyzed using principal component analysis and orthogonal partial least squares discriminant analysis. We identified 12 and 19 influential metabolites to discriminate between each origin fish in the warm and cold seasons, respectively, using variable importance in projection scores and p values. Anserine was further selected as a candidate biomarker based on receiver operating characteristic curve analysis. This study provides a basis for using anserine to determine the geographic origin of red seabream. Biomarker Metabolomics Chemometrics Liquid chromatography-mass spectrometry Origin discrimination Red seabream Shin, Jiyoung verfasserin aut Kim, Hyunsuk verfasserin aut Sim, Yikang verfasserin (orcid)0000-0002-0183-9639 aut Yang, Jiyoung verfasserin aut Enthalten in Food chemistry New York, NY [u.a.] : Elsevier, 1976 431 Online-Ressource (DE-627)300898509 (DE-600)1483647-6 (DE-576)098330225 1873-7072 nnns volume:431 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 58.34 Lebensmitteltechnologie VZ AR 431
spelling	10.1016/j.foodchem.2023.137129 doi (DE-627)ELV062630466 (ELSEVIER)S0308-8146(23)01747-8 DE-627 ger DE-627 rda eng 540 660 VZ 58.34 bkl Yang, Junho verfasserin aut Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream ( 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Red seabream (Pagrus major) is widely consumed in East Asia. As nuclear wastewater is discharged into Japanese waterbodies, the country of origin of marine products must be accurately labeled. Here, we aimed to discover candidate metabolite biomarkers to discriminate between Korean and Japanese red seabream using LC-Orbitrap mass spectrometry. In total, 95 and 138 putative metabolites were detected via chromatographic separation of fish sampled in the warm and cold seasons, respectively. The spectrometric and chromatographic data were analyzed using principal component analysis and orthogonal partial least squares discriminant analysis. We identified 12 and 19 influential metabolites to discriminate between each origin fish in the warm and cold seasons, respectively, using variable importance in projection scores and p values. Anserine was further selected as a candidate biomarker based on receiver operating characteristic curve analysis. This study provides a basis for using anserine to determine the geographic origin of red seabream. Biomarker Metabolomics Chemometrics Liquid chromatography-mass spectrometry Origin discrimination Red seabream Shin, Jiyoung verfasserin aut Kim, Hyunsuk verfasserin aut Sim, Yikang verfasserin (orcid)0000-0002-0183-9639 aut Yang, Jiyoung verfasserin aut Enthalten in Food chemistry New York, NY [u.a.] : Elsevier, 1976 431 Online-Ressource (DE-627)300898509 (DE-600)1483647-6 (DE-576)098330225 1873-7072 nnns volume:431 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 58.34 Lebensmitteltechnologie VZ AR 431
allfields_unstemmed	10.1016/j.foodchem.2023.137129 doi (DE-627)ELV062630466 (ELSEVIER)S0308-8146(23)01747-8 DE-627 ger DE-627 rda eng 540 660 VZ 58.34 bkl Yang, Junho verfasserin aut Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream ( 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Red seabream (Pagrus major) is widely consumed in East Asia. As nuclear wastewater is discharged into Japanese waterbodies, the country of origin of marine products must be accurately labeled. Here, we aimed to discover candidate metabolite biomarkers to discriminate between Korean and Japanese red seabream using LC-Orbitrap mass spectrometry. In total, 95 and 138 putative metabolites were detected via chromatographic separation of fish sampled in the warm and cold seasons, respectively. The spectrometric and chromatographic data were analyzed using principal component analysis and orthogonal partial least squares discriminant analysis. We identified 12 and 19 influential metabolites to discriminate between each origin fish in the warm and cold seasons, respectively, using variable importance in projection scores and p values. Anserine was further selected as a candidate biomarker based on receiver operating characteristic curve analysis. This study provides a basis for using anserine to determine the geographic origin of red seabream. Biomarker Metabolomics Chemometrics Liquid chromatography-mass spectrometry Origin discrimination Red seabream Shin, Jiyoung verfasserin aut Kim, Hyunsuk verfasserin aut Sim, Yikang verfasserin (orcid)0000-0002-0183-9639 aut Yang, Jiyoung verfasserin aut Enthalten in Food chemistry New York, NY [u.a.] : Elsevier, 1976 431 Online-Ressource (DE-627)300898509 (DE-600)1483647-6 (DE-576)098330225 1873-7072 nnns volume:431 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 58.34 Lebensmitteltechnologie VZ AR 431
allfieldsGer	10.1016/j.foodchem.2023.137129 doi (DE-627)ELV062630466 (ELSEVIER)S0308-8146(23)01747-8 DE-627 ger DE-627 rda eng 540 660 VZ 58.34 bkl Yang, Junho verfasserin aut Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream ( 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Red seabream (Pagrus major) is widely consumed in East Asia. As nuclear wastewater is discharged into Japanese waterbodies, the country of origin of marine products must be accurately labeled. Here, we aimed to discover candidate metabolite biomarkers to discriminate between Korean and Japanese red seabream using LC-Orbitrap mass spectrometry. In total, 95 and 138 putative metabolites were detected via chromatographic separation of fish sampled in the warm and cold seasons, respectively. The spectrometric and chromatographic data were analyzed using principal component analysis and orthogonal partial least squares discriminant analysis. We identified 12 and 19 influential metabolites to discriminate between each origin fish in the warm and cold seasons, respectively, using variable importance in projection scores and p values. Anserine was further selected as a candidate biomarker based on receiver operating characteristic curve analysis. This study provides a basis for using anserine to determine the geographic origin of red seabream. Biomarker Metabolomics Chemometrics Liquid chromatography-mass spectrometry Origin discrimination Red seabream Shin, Jiyoung verfasserin aut Kim, Hyunsuk verfasserin aut Sim, Yikang verfasserin (orcid)0000-0002-0183-9639 aut Yang, Jiyoung verfasserin aut Enthalten in Food chemistry New York, NY [u.a.] : Elsevier, 1976 431 Online-Ressource (DE-627)300898509 (DE-600)1483647-6 (DE-576)098330225 1873-7072 nnns volume:431 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 58.34 Lebensmitteltechnologie VZ AR 431
allfieldsSound	10.1016/j.foodchem.2023.137129 doi (DE-627)ELV062630466 (ELSEVIER)S0308-8146(23)01747-8 DE-627 ger DE-627 rda eng 540 660 VZ 58.34 bkl Yang, Junho verfasserin aut Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream ( 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Red seabream (Pagrus major) is widely consumed in East Asia. As nuclear wastewater is discharged into Japanese waterbodies, the country of origin of marine products must be accurately labeled. Here, we aimed to discover candidate metabolite biomarkers to discriminate between Korean and Japanese red seabream using LC-Orbitrap mass spectrometry. In total, 95 and 138 putative metabolites were detected via chromatographic separation of fish sampled in the warm and cold seasons, respectively. The spectrometric and chromatographic data were analyzed using principal component analysis and orthogonal partial least squares discriminant analysis. We identified 12 and 19 influential metabolites to discriminate between each origin fish in the warm and cold seasons, respectively, using variable importance in projection scores and p values. Anserine was further selected as a candidate biomarker based on receiver operating characteristic curve analysis. This study provides a basis for using anserine to determine the geographic origin of red seabream. Biomarker Metabolomics Chemometrics Liquid chromatography-mass spectrometry Origin discrimination Red seabream Shin, Jiyoung verfasserin aut Kim, Hyunsuk verfasserin aut Sim, Yikang verfasserin (orcid)0000-0002-0183-9639 aut Yang, Jiyoung verfasserin aut Enthalten in Food chemistry New York, NY [u.a.] : Elsevier, 1976 431 Online-Ressource (DE-627)300898509 (DE-600)1483647-6 (DE-576)098330225 1873-7072 nnns volume:431 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 58.34 Lebensmitteltechnologie VZ AR 431
language	English
source	Enthalten in Food chemistry 431 volume:431
sourceStr	Enthalten in Food chemistry 431 volume:431
format_phy_str_mv	Article
bklname	Lebensmitteltechnologie
institution	findex.gbv.de
topic_facet	Biomarker Metabolomics Chemometrics Liquid chromatography-mass spectrometry Origin discrimination Red seabream
dewey-raw	540
isfreeaccess_bool	false
container_title	Food chemistry
authorswithroles_txt_mv	Yang, Junho @@aut@@ Shin, Jiyoung @@aut@@ Kim, Hyunsuk @@aut@@ Sim, Yikang @@aut@@ Yang, Jiyoung @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	300898509
dewey-sort	3540
id	ELV062630466
language_de	englisch
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author	Yang, Junho
spellingShingle	Yang, Junho ddc 540 bkl 58.34 misc Biomarker misc Metabolomics misc Chemometrics misc Liquid chromatography-mass spectrometry misc Origin discrimination misc Red seabream Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream (
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topic_title	540 660 VZ 58.34 bkl Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream ( Biomarker Metabolomics Chemometrics Liquid chromatography-mass spectrometry Origin discrimination Red seabream
topic	ddc 540 bkl 58.34 misc Biomarker misc Metabolomics misc Chemometrics misc Liquid chromatography-mass spectrometry misc Origin discrimination misc Red seabream
topic_unstemmed	ddc 540 bkl 58.34 misc Biomarker misc Metabolomics misc Chemometrics misc Liquid chromatography-mass spectrometry misc Origin discrimination misc Red seabream
topic_browse	ddc 540 bkl 58.34 misc Biomarker misc Metabolomics misc Chemometrics misc Liquid chromatography-mass spectrometry misc Origin discrimination misc Red seabream
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title	Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream (
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title_full	Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream (
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title_sort	discovery of candidate biomarkers to discriminate between korean and japanese red seabream (
title_auth	Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream (
abstract	Red seabream (Pagrus major) is widely consumed in East Asia. As nuclear wastewater is discharged into Japanese waterbodies, the country of origin of marine products must be accurately labeled. Here, we aimed to discover candidate metabolite biomarkers to discriminate between Korean and Japanese red seabream using LC-Orbitrap mass spectrometry. In total, 95 and 138 putative metabolites were detected via chromatographic separation of fish sampled in the warm and cold seasons, respectively. The spectrometric and chromatographic data were analyzed using principal component analysis and orthogonal partial least squares discriminant analysis. We identified 12 and 19 influential metabolites to discriminate between each origin fish in the warm and cold seasons, respectively, using variable importance in projection scores and p values. Anserine was further selected as a candidate biomarker based on receiver operating characteristic curve analysis. This study provides a basis for using anserine to determine the geographic origin of red seabream.
abstractGer	Red seabream (Pagrus major) is widely consumed in East Asia. As nuclear wastewater is discharged into Japanese waterbodies, the country of origin of marine products must be accurately labeled. Here, we aimed to discover candidate metabolite biomarkers to discriminate between Korean and Japanese red seabream using LC-Orbitrap mass spectrometry. In total, 95 and 138 putative metabolites were detected via chromatographic separation of fish sampled in the warm and cold seasons, respectively. The spectrometric and chromatographic data were analyzed using principal component analysis and orthogonal partial least squares discriminant analysis. We identified 12 and 19 influential metabolites to discriminate between each origin fish in the warm and cold seasons, respectively, using variable importance in projection scores and p values. Anserine was further selected as a candidate biomarker based on receiver operating characteristic curve analysis. This study provides a basis for using anserine to determine the geographic origin of red seabream.
abstract_unstemmed	Red seabream (Pagrus major) is widely consumed in East Asia. As nuclear wastewater is discharged into Japanese waterbodies, the country of origin of marine products must be accurately labeled. Here, we aimed to discover candidate metabolite biomarkers to discriminate between Korean and Japanese red seabream using LC-Orbitrap mass spectrometry. In total, 95 and 138 putative metabolites were detected via chromatographic separation of fish sampled in the warm and cold seasons, respectively. The spectrometric and chromatographic data were analyzed using principal component analysis and orthogonal partial least squares discriminant analysis. We identified 12 and 19 influential metabolites to discriminate between each origin fish in the warm and cold seasons, respectively, using variable importance in projection scores and p values. Anserine was further selected as a candidate biomarker based on receiver operating characteristic curve analysis. This study provides a basis for using anserine to determine the geographic origin of red seabream.
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title_short	Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream (
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author2	Shin, Jiyoung Kim, Hyunsuk Sim, Yikang Yang, Jiyoung
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doi_str	10.1016/j.foodchem.2023.137129
up_date	2024-07-06T19:00:43.710Z
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Discovery of candidate biomarkers to discriminate between Korean and Japanese red seabream (

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