Effect of nano-metal oxides (TiO

The global threat of infectious diseases and antibiotic resistance calls for the development of potent antimicrobial agents integrated with hydrogel for effective control and treatment. Hydrogel is advanced biomaterials compounds. Hydrogel is an advanced biomaterial compound that offers tunable physical and chemical properties, which can be tailored to specific biomedical applications. This study investigates the antibacterial properties of pectin/polyethylene oxide (PEC/PEO)-based poly acrylamide hydrogels containing 5 wt% nano-metal oxides (TiO2, CaO, MgO, and ZnO) synthesized through gamma irradiation at a dose of 30 kGy. This technique allows for sterilization and effectively incorporating the metal oxide nanoparticles within the hydrogel matrix. Characterization of the nanocomposites is performed using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Incorporating metal oxide nanoparticles induces noticeable changes in the FTIR spectra, confirming interactions between the nanoparticles and the hydrogel matrix. The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. Incorporating nanoparticles into a hydrogel matrix introduces novelty by preventing their aggregation and synergistically enhancing the antibacterial activity. The hydrogel's porous structure and water content facilitate the physical entrapment of bacteria and promote proximity to the metal oxide nanoparticles, resulting in improved interaction and antimicrobial effectiveness. Moreover, the hydrogel ability to absorb and entrap resistance compounds released by bacteria, coupled with its ability to supply water for the generation of reactive oxygen species, further contributes to its antimicrobial properties. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	El Fadl, Faten Ismail Abou [verfasserIn] Hegazy, Dalia E. [verfasserIn] Maziad, Nabila A. [verfasserIn] Ghobashy, Mohamed Mohamady [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Pectin Gamma irradiation Acrylamide Nanocomposite hydrogel biomaterial Metal oxides Antimicrobial property

Übergeordnetes Werk:	Enthalten in: International journal of biological macromolecules - New York, NY [u.a.] : Elsevier, 1979, 250
Übergeordnetes Werk:	volume:250

DOI / URN:	10.1016/j.ijbiomac.2023.126248

Katalog-ID:	ELV065132785

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650		4	\|a Pectin
650		4	\|a Gamma irradiation
650		4	\|a Acrylamide
650		4	\|a Nanocomposite hydrogel biomaterial
650		4	\|a Metal oxides
650		4	\|a Antimicrobial property
700	1		\|a Hegazy, Dalia E. \|e verfasserin \|4 aut
700	1		\|a Maziad, Nabila A. \|e verfasserin \|4 aut
700	1		\|a Ghobashy, Mohamed Mohamady \|e verfasserin \|4 aut
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912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2110
912			\|a GBV_ILN_2111
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912			\|a GBV_ILN_2470
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
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allfields	10.1016/j.ijbiomac.2023.126248 doi (DE-627)ELV065132785 (ELSEVIER)S0141-8130(23)03144-6 DE-627 ger DE-627 rda eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl El Fadl, Faten Ismail Abou verfasserin aut Effect of nano-metal oxides (TiO 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The global threat of infectious diseases and antibiotic resistance calls for the development of potent antimicrobial agents integrated with hydrogel for effective control and treatment. Hydrogel is advanced biomaterials compounds. Hydrogel is an advanced biomaterial compound that offers tunable physical and chemical properties, which can be tailored to specific biomedical applications. This study investigates the antibacterial properties of pectin/polyethylene oxide (PEC/PEO)-based poly acrylamide hydrogels containing 5 wt% nano-metal oxides (TiO2, CaO, MgO, and ZnO) synthesized through gamma irradiation at a dose of 30 kGy. This technique allows for sterilization and effectively incorporating the metal oxide nanoparticles within the hydrogel matrix. Characterization of the nanocomposites is performed using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Incorporating metal oxide nanoparticles induces noticeable changes in the FTIR spectra, confirming interactions between the nanoparticles and the hydrogel matrix. The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. Incorporating nanoparticles into a hydrogel matrix introduces novelty by preventing their aggregation and synergistically enhancing the antibacterial activity. The hydrogel's porous structure and water content facilitate the physical entrapment of bacteria and promote proximity to the metal oxide nanoparticles, resulting in improved interaction and antimicrobial effectiveness. Moreover, the hydrogel ability to absorb and entrap resistance compounds released by bacteria, coupled with its ability to supply water for the generation of reactive oxygen species, further contributes to its antimicrobial properties. Pectin Gamma irradiation Acrylamide Nanocomposite hydrogel biomaterial Metal oxides Antimicrobial property Hegazy, Dalia E. verfasserin aut Maziad, Nabila A. verfasserin aut Ghobashy, Mohamed Mohamady verfasserin aut Enthalten in International journal of biological macromolecules New York, NY [u.a.] : Elsevier, 1979 250 Online-Ressource (DE-627)30089502X (DE-600)1483284-7 (DE-576)259270814 1879-0003 nnns volume:250 GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 250
spelling	10.1016/j.ijbiomac.2023.126248 doi (DE-627)ELV065132785 (ELSEVIER)S0141-8130(23)03144-6 DE-627 ger DE-627 rda eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl El Fadl, Faten Ismail Abou verfasserin aut Effect of nano-metal oxides (TiO 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The global threat of infectious diseases and antibiotic resistance calls for the development of potent antimicrobial agents integrated with hydrogel for effective control and treatment. Hydrogel is advanced biomaterials compounds. Hydrogel is an advanced biomaterial compound that offers tunable physical and chemical properties, which can be tailored to specific biomedical applications. This study investigates the antibacterial properties of pectin/polyethylene oxide (PEC/PEO)-based poly acrylamide hydrogels containing 5 wt% nano-metal oxides (TiO2, CaO, MgO, and ZnO) synthesized through gamma irradiation at a dose of 30 kGy. This technique allows for sterilization and effectively incorporating the metal oxide nanoparticles within the hydrogel matrix. Characterization of the nanocomposites is performed using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Incorporating metal oxide nanoparticles induces noticeable changes in the FTIR spectra, confirming interactions between the nanoparticles and the hydrogel matrix. The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. Incorporating nanoparticles into a hydrogel matrix introduces novelty by preventing their aggregation and synergistically enhancing the antibacterial activity. The hydrogel's porous structure and water content facilitate the physical entrapment of bacteria and promote proximity to the metal oxide nanoparticles, resulting in improved interaction and antimicrobial effectiveness. Moreover, the hydrogel ability to absorb and entrap resistance compounds released by bacteria, coupled with its ability to supply water for the generation of reactive oxygen species, further contributes to its antimicrobial properties. Pectin Gamma irradiation Acrylamide Nanocomposite hydrogel biomaterial Metal oxides Antimicrobial property Hegazy, Dalia E. verfasserin aut Maziad, Nabila A. verfasserin aut Ghobashy, Mohamed Mohamady verfasserin aut Enthalten in International journal of biological macromolecules New York, NY [u.a.] : Elsevier, 1979 250 Online-Ressource (DE-627)30089502X (DE-600)1483284-7 (DE-576)259270814 1879-0003 nnns volume:250 GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 250
allfields_unstemmed	10.1016/j.ijbiomac.2023.126248 doi (DE-627)ELV065132785 (ELSEVIER)S0141-8130(23)03144-6 DE-627 ger DE-627 rda eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl El Fadl, Faten Ismail Abou verfasserin aut Effect of nano-metal oxides (TiO 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The global threat of infectious diseases and antibiotic resistance calls for the development of potent antimicrobial agents integrated with hydrogel for effective control and treatment. Hydrogel is advanced biomaterials compounds. Hydrogel is an advanced biomaterial compound that offers tunable physical and chemical properties, which can be tailored to specific biomedical applications. This study investigates the antibacterial properties of pectin/polyethylene oxide (PEC/PEO)-based poly acrylamide hydrogels containing 5 wt% nano-metal oxides (TiO2, CaO, MgO, and ZnO) synthesized through gamma irradiation at a dose of 30 kGy. This technique allows for sterilization and effectively incorporating the metal oxide nanoparticles within the hydrogel matrix. Characterization of the nanocomposites is performed using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Incorporating metal oxide nanoparticles induces noticeable changes in the FTIR spectra, confirming interactions between the nanoparticles and the hydrogel matrix. The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. Incorporating nanoparticles into a hydrogel matrix introduces novelty by preventing their aggregation and synergistically enhancing the antibacterial activity. The hydrogel's porous structure and water content facilitate the physical entrapment of bacteria and promote proximity to the metal oxide nanoparticles, resulting in improved interaction and antimicrobial effectiveness. Moreover, the hydrogel ability to absorb and entrap resistance compounds released by bacteria, coupled with its ability to supply water for the generation of reactive oxygen species, further contributes to its antimicrobial properties. Pectin Gamma irradiation Acrylamide Nanocomposite hydrogel biomaterial Metal oxides Antimicrobial property Hegazy, Dalia E. verfasserin aut Maziad, Nabila A. verfasserin aut Ghobashy, Mohamed Mohamady verfasserin aut Enthalten in International journal of biological macromolecules New York, NY [u.a.] : Elsevier, 1979 250 Online-Ressource (DE-627)30089502X (DE-600)1483284-7 (DE-576)259270814 1879-0003 nnns volume:250 GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 250
allfieldsGer	10.1016/j.ijbiomac.2023.126248 doi (DE-627)ELV065132785 (ELSEVIER)S0141-8130(23)03144-6 DE-627 ger DE-627 rda eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl El Fadl, Faten Ismail Abou verfasserin aut Effect of nano-metal oxides (TiO 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The global threat of infectious diseases and antibiotic resistance calls for the development of potent antimicrobial agents integrated with hydrogel for effective control and treatment. Hydrogel is advanced biomaterials compounds. Hydrogel is an advanced biomaterial compound that offers tunable physical and chemical properties, which can be tailored to specific biomedical applications. This study investigates the antibacterial properties of pectin/polyethylene oxide (PEC/PEO)-based poly acrylamide hydrogels containing 5 wt% nano-metal oxides (TiO2, CaO, MgO, and ZnO) synthesized through gamma irradiation at a dose of 30 kGy. This technique allows for sterilization and effectively incorporating the metal oxide nanoparticles within the hydrogel matrix. Characterization of the nanocomposites is performed using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Incorporating metal oxide nanoparticles induces noticeable changes in the FTIR spectra, confirming interactions between the nanoparticles and the hydrogel matrix. The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. Incorporating nanoparticles into a hydrogel matrix introduces novelty by preventing their aggregation and synergistically enhancing the antibacterial activity. The hydrogel's porous structure and water content facilitate the physical entrapment of bacteria and promote proximity to the metal oxide nanoparticles, resulting in improved interaction and antimicrobial effectiveness. Moreover, the hydrogel ability to absorb and entrap resistance compounds released by bacteria, coupled with its ability to supply water for the generation of reactive oxygen species, further contributes to its antimicrobial properties. Pectin Gamma irradiation Acrylamide Nanocomposite hydrogel biomaterial Metal oxides Antimicrobial property Hegazy, Dalia E. verfasserin aut Maziad, Nabila A. verfasserin aut Ghobashy, Mohamed Mohamady verfasserin aut Enthalten in International journal of biological macromolecules New York, NY [u.a.] : Elsevier, 1979 250 Online-Ressource (DE-627)30089502X (DE-600)1483284-7 (DE-576)259270814 1879-0003 nnns volume:250 GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 250
allfieldsSound	10.1016/j.ijbiomac.2023.126248 doi (DE-627)ELV065132785 (ELSEVIER)S0141-8130(23)03144-6 DE-627 ger DE-627 rda eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl El Fadl, Faten Ismail Abou verfasserin aut Effect of nano-metal oxides (TiO 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The global threat of infectious diseases and antibiotic resistance calls for the development of potent antimicrobial agents integrated with hydrogel for effective control and treatment. Hydrogel is advanced biomaterials compounds. Hydrogel is an advanced biomaterial compound that offers tunable physical and chemical properties, which can be tailored to specific biomedical applications. This study investigates the antibacterial properties of pectin/polyethylene oxide (PEC/PEO)-based poly acrylamide hydrogels containing 5 wt% nano-metal oxides (TiO2, CaO, MgO, and ZnO) synthesized through gamma irradiation at a dose of 30 kGy. This technique allows for sterilization and effectively incorporating the metal oxide nanoparticles within the hydrogel matrix. Characterization of the nanocomposites is performed using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Incorporating metal oxide nanoparticles induces noticeable changes in the FTIR spectra, confirming interactions between the nanoparticles and the hydrogel matrix. The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. Incorporating nanoparticles into a hydrogel matrix introduces novelty by preventing their aggregation and synergistically enhancing the antibacterial activity. The hydrogel's porous structure and water content facilitate the physical entrapment of bacteria and promote proximity to the metal oxide nanoparticles, resulting in improved interaction and antimicrobial effectiveness. Moreover, the hydrogel ability to absorb and entrap resistance compounds released by bacteria, coupled with its ability to supply water for the generation of reactive oxygen species, further contributes to its antimicrobial properties. Pectin Gamma irradiation Acrylamide Nanocomposite hydrogel biomaterial Metal oxides Antimicrobial property Hegazy, Dalia E. verfasserin aut Maziad, Nabila A. verfasserin aut Ghobashy, Mohamed Mohamady verfasserin aut Enthalten in International journal of biological macromolecules New York, NY [u.a.] : Elsevier, 1979 250 Online-Ressource (DE-627)30089502X (DE-600)1483284-7 (DE-576)259270814 1879-0003 nnns volume:250 GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 250
language	English
source	Enthalten in International journal of biological macromolecules 250 volume:250
sourceStr	Enthalten in International journal of biological macromolecules 250 volume:250
format_phy_str_mv	Article
bklname	Makromolekulare Chemie Biotechnologie
institution	findex.gbv.de
topic_facet	Pectin Gamma irradiation Acrylamide Nanocomposite hydrogel biomaterial Metal oxides Antimicrobial property
dewey-raw	540
isfreeaccess_bool	false
container_title	International journal of biological macromolecules
authorswithroles_txt_mv	El Fadl, Faten Ismail Abou @@aut@@ Hegazy, Dalia E. @@aut@@ Maziad, Nabila A. @@aut@@ Ghobashy, Mohamed Mohamady @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	30089502X
dewey-sort	3540
id	ELV065132785
language_de	englisch
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The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. 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author	El Fadl, Faten Ismail Abou
spellingShingle	El Fadl, Faten Ismail Abou ddc 540 fid BIODIV bkl 35.80 bkl 58.30 misc Pectin misc Gamma irradiation misc Acrylamide misc Nanocomposite hydrogel biomaterial misc Metal oxides misc Antimicrobial property Effect of nano-metal oxides (TiO
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topic_title	540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Effect of nano-metal oxides (TiO Pectin Gamma irradiation Acrylamide Nanocomposite hydrogel biomaterial Metal oxides Antimicrobial property
topic	ddc 540 fid BIODIV bkl 35.80 bkl 58.30 misc Pectin misc Gamma irradiation misc Acrylamide misc Nanocomposite hydrogel biomaterial misc Metal oxides misc Antimicrobial property
topic_unstemmed	ddc 540 fid BIODIV bkl 35.80 bkl 58.30 misc Pectin misc Gamma irradiation misc Acrylamide misc Nanocomposite hydrogel biomaterial misc Metal oxides misc Antimicrobial property
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title	Effect of nano-metal oxides (TiO
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title_full	Effect of nano-metal oxides (TiO
author_sort	El Fadl, Faten Ismail Abou
journal	International journal of biological macromolecules
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author_browse	El Fadl, Faten Ismail Abou Hegazy, Dalia E. Maziad, Nabila A. Ghobashy, Mohamed Mohamady
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author-letter	El Fadl, Faten Ismail Abou
doi_str_mv	10.1016/j.ijbiomac.2023.126248
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title_sort	effect of nano-metal oxides (tio
title_auth	Effect of nano-metal oxides (TiO
abstract	The global threat of infectious diseases and antibiotic resistance calls for the development of potent antimicrobial agents integrated with hydrogel for effective control and treatment. Hydrogel is advanced biomaterials compounds. Hydrogel is an advanced biomaterial compound that offers tunable physical and chemical properties, which can be tailored to specific biomedical applications. This study investigates the antibacterial properties of pectin/polyethylene oxide (PEC/PEO)-based poly acrylamide hydrogels containing 5 wt% nano-metal oxides (TiO2, CaO, MgO, and ZnO) synthesized through gamma irradiation at a dose of 30 kGy. This technique allows for sterilization and effectively incorporating the metal oxide nanoparticles within the hydrogel matrix. Characterization of the nanocomposites is performed using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Incorporating metal oxide nanoparticles induces noticeable changes in the FTIR spectra, confirming interactions between the nanoparticles and the hydrogel matrix. The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. Incorporating nanoparticles into a hydrogel matrix introduces novelty by preventing their aggregation and synergistically enhancing the antibacterial activity. The hydrogel's porous structure and water content facilitate the physical entrapment of bacteria and promote proximity to the metal oxide nanoparticles, resulting in improved interaction and antimicrobial effectiveness. Moreover, the hydrogel ability to absorb and entrap resistance compounds released by bacteria, coupled with its ability to supply water for the generation of reactive oxygen species, further contributes to its antimicrobial properties.
abstractGer	The global threat of infectious diseases and antibiotic resistance calls for the development of potent antimicrobial agents integrated with hydrogel for effective control and treatment. Hydrogel is advanced biomaterials compounds. Hydrogel is an advanced biomaterial compound that offers tunable physical and chemical properties, which can be tailored to specific biomedical applications. This study investigates the antibacterial properties of pectin/polyethylene oxide (PEC/PEO)-based poly acrylamide hydrogels containing 5 wt% nano-metal oxides (TiO2, CaO, MgO, and ZnO) synthesized through gamma irradiation at a dose of 30 kGy. This technique allows for sterilization and effectively incorporating the metal oxide nanoparticles within the hydrogel matrix. Characterization of the nanocomposites is performed using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Incorporating metal oxide nanoparticles induces noticeable changes in the FTIR spectra, confirming interactions between the nanoparticles and the hydrogel matrix. The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. Incorporating nanoparticles into a hydrogel matrix introduces novelty by preventing their aggregation and synergistically enhancing the antibacterial activity. The hydrogel's porous structure and water content facilitate the physical entrapment of bacteria and promote proximity to the metal oxide nanoparticles, resulting in improved interaction and antimicrobial effectiveness. Moreover, the hydrogel ability to absorb and entrap resistance compounds released by bacteria, coupled with its ability to supply water for the generation of reactive oxygen species, further contributes to its antimicrobial properties.
abstract_unstemmed	The global threat of infectious diseases and antibiotic resistance calls for the development of potent antimicrobial agents integrated with hydrogel for effective control and treatment. Hydrogel is advanced biomaterials compounds. Hydrogel is an advanced biomaterial compound that offers tunable physical and chemical properties, which can be tailored to specific biomedical applications. This study investigates the antibacterial properties of pectin/polyethylene oxide (PEC/PEO)-based poly acrylamide hydrogels containing 5 wt% nano-metal oxides (TiO2, CaO, MgO, and ZnO) synthesized through gamma irradiation at a dose of 30 kGy. This technique allows for sterilization and effectively incorporating the metal oxide nanoparticles within the hydrogel matrix. Characterization of the nanocomposites is performed using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Incorporating metal oxide nanoparticles induces noticeable changes in the FTIR spectra, confirming interactions between the nanoparticles and the hydrogel matrix. The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. Incorporating nanoparticles into a hydrogel matrix introduces novelty by preventing their aggregation and synergistically enhancing the antibacterial activity. The hydrogel's porous structure and water content facilitate the physical entrapment of bacteria and promote proximity to the metal oxide nanoparticles, resulting in improved interaction and antimicrobial effectiveness. Moreover, the hydrogel ability to absorb and entrap resistance compounds released by bacteria, coupled with its ability to supply water for the generation of reactive oxygen species, further contributes to its antimicrobial properties.
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title_short	Effect of nano-metal oxides (TiO
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author2	Hegazy, Dalia E. Maziad, Nabila A. Ghobashy, Mohamed Mohamady
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doi_str	10.1016/j.ijbiomac.2023.126248
up_date	2024-07-06T21:56:58.234Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV065132785</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20231123093121.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">231014s2023 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.ijbiomac.2023.126248</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV065132785</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0141-8130(23)03144-6</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">540</subfield><subfield code="a">570</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">BIODIV</subfield><subfield code="q">DE-30</subfield><subfield code="2">fid</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">35.80</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">58.30</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">El Fadl, Faten Ismail Abou</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Effect of nano-metal oxides (TiO</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2023</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The global threat of infectious diseases and antibiotic resistance calls for the development of potent antimicrobial agents integrated with hydrogel for effective control and treatment. Hydrogel is advanced biomaterials compounds. Hydrogel is an advanced biomaterial compound that offers tunable physical and chemical properties, which can be tailored to specific biomedical applications. This study investigates the antibacterial properties of pectin/polyethylene oxide (PEC/PEO)-based poly acrylamide hydrogels containing 5 wt% nano-metal oxides (TiO2, CaO, MgO, and ZnO) synthesized through gamma irradiation at a dose of 30 kGy. This technique allows for sterilization and effectively incorporating the metal oxide nanoparticles within the hydrogel matrix. Characterization of the nanocomposites is performed using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Incorporating metal oxide nanoparticles induces noticeable changes in the FTIR spectra, confirming interactions between the nanoparticles and the hydrogel matrix. The antibacterial activity of the nanocomposites is evaluated against different bacteria, and the results demonstrate significant inhibitory effects, especially for MgO- and ZnO-hydrogel nanocomposites against P. mirabilis, S. aureus, P. aeruginosa, and C. albicans, highlighting their potential as antimicrobial agents. The 5 wt% of MgO, ZnO, TiO2 and CaO inside PEO/PEC-co-AAm hydrogel nanocomposites exhibited significant inhibitory effects, with a respective optical density at λ = 600 nm (OD600) values of 0.896 nm, 0.986 nm, 1.250 nm, and 1.980 nm compared to the control and hydrogel alone (OD600 values of 2.88 nm and 2.72 nm, respectively). The antibacterial activity of the (MgO-, ZnO-, TiO2-, and CaO-hydrogel) was enhanced, resulting in the inhibition of S. aureus growth by approximately 68.89 %, 65.86 %, 56.25 %, and 31.94 %, respectively. Incorporating nanoparticles into a hydrogel matrix introduces novelty by preventing their aggregation and synergistically enhancing the antibacterial activity. The hydrogel's porous structure and water content facilitate the physical entrapment of bacteria and promote proximity to the metal oxide nanoparticles, resulting in improved interaction and antimicrobial effectiveness. 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Effect of nano-metal oxides (TiO

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