A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish
Hypochlorite (ClO−) plays an important role in many cellular processes, which is proved to be related to some serious diseases. Given the electron donating and electron withdrawing properties of benzo[h]chromene and rhodanine groups, respectively, we developed a Donor (D)-p-Acceptor (A) type probe 1...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Jin, Kun-Sheng [verfasserIn] Yan, Jin-Long [verfasserIn] Wu, Wei-Na [verfasserIn] Zhao, Xiao-Lei [verfasserIn] Wang, Yuan [verfasserIn] Fan, Yun-Chang [verfasserIn] Li, Xiao-Xia [verfasserIn] Xu, Zhi-Hong [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2023 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Journal of molecular structure - New York, NY [u.a.] : Elsevier, 1967, 1295 |
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| Übergeordnetes Werk: |
volume:1295 |
| DOI / URN: |
10.1016/j.molstruc.2023.136697 |
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| Katalog-ID: |
ELV065232143 |
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| 024 | 7 | |a 10.1016/j.molstruc.2023.136697 |2 doi | |
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| 245 | 1 | 0 | |a A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish |
| 264 | 1 | |c 2023 | |
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| 337 | |a Computermedien |b c |2 rdamedia | ||
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| 520 | |a Hypochlorite (ClO−) plays an important role in many cellular processes, which is proved to be related to some serious diseases. Given the electron donating and electron withdrawing properties of benzo[h]chromene and rhodanine groups, respectively, we developed a Donor (D)-p-Acceptor (A) type probe 1 for the detection of ClO− based on benzo[h]chromene (D) and rhodanine (A), whose structure was determined by ESI-MS, NMR and X-ray diffraction. Probe 1 showed a fast (within 20 s), selective and sensitive response toward ClO− via a fluorescent turn-on output. Based-on the spectral change of probe 1 induced by ClO−, the mechanism associated with oxidation breakage of rhodanine moiety was proposed. Due to the excellent biocompatibility and low cytotoxicity, probe 1 can be used for imaging of ClO− in C6 cells, Arabidopsis thaliana, and zebrafish. | ||
| 650 | 4 | |a Benzo[ | |
| 650 | 4 | |a Biological imaging | |
| 650 | 4 | |a Hypochlorite | |
| 650 | 4 | |a Probe | |
| 650 | 4 | |a Rhodanine | |
| 700 | 1 | |a Yan, Jin-Long |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Wei-Na |e verfasserin |4 aut | |
| 700 | 1 | |a Zhao, Xiao-Lei |e verfasserin |0 (orcid)0000-0002-2521-2144 |4 aut | |
| 700 | 1 | |a Wang, Yuan |e verfasserin |4 aut | |
| 700 | 1 | |a Fan, Yun-Chang |e verfasserin |0 (orcid)0000-0003-4237-9242 |4 aut | |
| 700 | 1 | |a Li, Xiao-Xia |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Zhi-Hong |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of molecular structure |d New York, NY [u.a.] : Elsevier, 1967 |g 1295 |h Online-Ressource |w (DE-627)302469745 |w (DE-600)1491504-2 |w (DE-576)255266626 |x 0022-2860 |7 nnns |
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| 912 | |a GBV_ILN_602 | ||
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| 912 | |a GBV_ILN_4249 | ||
| 912 | |a GBV_ILN_4251 | ||
| 912 | |a GBV_ILN_4305 | ||
| 912 | |a GBV_ILN_4306 | ||
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10.1016/j.molstruc.2023.136697 doi (DE-627)ELV065232143 (ELSEVIER)S0022-2860(23)01787-8 DE-627 ger DE-627 rda eng 540 VZ 35.00 bkl Jin, Kun-Sheng verfasserin aut A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hypochlorite (ClO−) plays an important role in many cellular processes, which is proved to be related to some serious diseases. Given the electron donating and electron withdrawing properties of benzo[h]chromene and rhodanine groups, respectively, we developed a Donor (D)-p-Acceptor (A) type probe 1 for the detection of ClO− based on benzo[h]chromene (D) and rhodanine (A), whose structure was determined by ESI-MS, NMR and X-ray diffraction. Probe 1 showed a fast (within 20 s), selective and sensitive response toward ClO− via a fluorescent turn-on output. Based-on the spectral change of probe 1 induced by ClO−, the mechanism associated with oxidation breakage of rhodanine moiety was proposed. Due to the excellent biocompatibility and low cytotoxicity, probe 1 can be used for imaging of ClO− in C6 cells, Arabidopsis thaliana, and zebrafish. Benzo[ Biological imaging Hypochlorite Probe Rhodanine Yan, Jin-Long verfasserin aut Wu, Wei-Na verfasserin aut Zhao, Xiao-Lei verfasserin (orcid)0000-0002-2521-2144 aut Wang, Yuan verfasserin aut Fan, Yun-Chang verfasserin (orcid)0000-0003-4237-9242 aut Li, Xiao-Xia verfasserin aut Xu, Zhi-Hong verfasserin aut Enthalten in Journal of molecular structure New York, NY [u.a.] : Elsevier, 1967 1295 Online-Ressource (DE-627)302469745 (DE-600)1491504-2 (DE-576)255266626 0022-2860 nnns volume:1295 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.00 Chemie: Allgemeines VZ AR 1295 |
| spelling |
10.1016/j.molstruc.2023.136697 doi (DE-627)ELV065232143 (ELSEVIER)S0022-2860(23)01787-8 DE-627 ger DE-627 rda eng 540 VZ 35.00 bkl Jin, Kun-Sheng verfasserin aut A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hypochlorite (ClO−) plays an important role in many cellular processes, which is proved to be related to some serious diseases. Given the electron donating and electron withdrawing properties of benzo[h]chromene and rhodanine groups, respectively, we developed a Donor (D)-p-Acceptor (A) type probe 1 for the detection of ClO− based on benzo[h]chromene (D) and rhodanine (A), whose structure was determined by ESI-MS, NMR and X-ray diffraction. Probe 1 showed a fast (within 20 s), selective and sensitive response toward ClO− via a fluorescent turn-on output. Based-on the spectral change of probe 1 induced by ClO−, the mechanism associated with oxidation breakage of rhodanine moiety was proposed. Due to the excellent biocompatibility and low cytotoxicity, probe 1 can be used for imaging of ClO− in C6 cells, Arabidopsis thaliana, and zebrafish. Benzo[ Biological imaging Hypochlorite Probe Rhodanine Yan, Jin-Long verfasserin aut Wu, Wei-Na verfasserin aut Zhao, Xiao-Lei verfasserin (orcid)0000-0002-2521-2144 aut Wang, Yuan verfasserin aut Fan, Yun-Chang verfasserin (orcid)0000-0003-4237-9242 aut Li, Xiao-Xia verfasserin aut Xu, Zhi-Hong verfasserin aut Enthalten in Journal of molecular structure New York, NY [u.a.] : Elsevier, 1967 1295 Online-Ressource (DE-627)302469745 (DE-600)1491504-2 (DE-576)255266626 0022-2860 nnns volume:1295 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.00 Chemie: Allgemeines VZ AR 1295 |
| allfields_unstemmed |
10.1016/j.molstruc.2023.136697 doi (DE-627)ELV065232143 (ELSEVIER)S0022-2860(23)01787-8 DE-627 ger DE-627 rda eng 540 VZ 35.00 bkl Jin, Kun-Sheng verfasserin aut A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hypochlorite (ClO−) plays an important role in many cellular processes, which is proved to be related to some serious diseases. Given the electron donating and electron withdrawing properties of benzo[h]chromene and rhodanine groups, respectively, we developed a Donor (D)-p-Acceptor (A) type probe 1 for the detection of ClO− based on benzo[h]chromene (D) and rhodanine (A), whose structure was determined by ESI-MS, NMR and X-ray diffraction. Probe 1 showed a fast (within 20 s), selective and sensitive response toward ClO− via a fluorescent turn-on output. Based-on the spectral change of probe 1 induced by ClO−, the mechanism associated with oxidation breakage of rhodanine moiety was proposed. Due to the excellent biocompatibility and low cytotoxicity, probe 1 can be used for imaging of ClO− in C6 cells, Arabidopsis thaliana, and zebrafish. Benzo[ Biological imaging Hypochlorite Probe Rhodanine Yan, Jin-Long verfasserin aut Wu, Wei-Na verfasserin aut Zhao, Xiao-Lei verfasserin (orcid)0000-0002-2521-2144 aut Wang, Yuan verfasserin aut Fan, Yun-Chang verfasserin (orcid)0000-0003-4237-9242 aut Li, Xiao-Xia verfasserin aut Xu, Zhi-Hong verfasserin aut Enthalten in Journal of molecular structure New York, NY [u.a.] : Elsevier, 1967 1295 Online-Ressource (DE-627)302469745 (DE-600)1491504-2 (DE-576)255266626 0022-2860 nnns volume:1295 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.00 Chemie: Allgemeines VZ AR 1295 |
| allfieldsGer |
10.1016/j.molstruc.2023.136697 doi (DE-627)ELV065232143 (ELSEVIER)S0022-2860(23)01787-8 DE-627 ger DE-627 rda eng 540 VZ 35.00 bkl Jin, Kun-Sheng verfasserin aut A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hypochlorite (ClO−) plays an important role in many cellular processes, which is proved to be related to some serious diseases. Given the electron donating and electron withdrawing properties of benzo[h]chromene and rhodanine groups, respectively, we developed a Donor (D)-p-Acceptor (A) type probe 1 for the detection of ClO− based on benzo[h]chromene (D) and rhodanine (A), whose structure was determined by ESI-MS, NMR and X-ray diffraction. Probe 1 showed a fast (within 20 s), selective and sensitive response toward ClO− via a fluorescent turn-on output. Based-on the spectral change of probe 1 induced by ClO−, the mechanism associated with oxidation breakage of rhodanine moiety was proposed. Due to the excellent biocompatibility and low cytotoxicity, probe 1 can be used for imaging of ClO− in C6 cells, Arabidopsis thaliana, and zebrafish. Benzo[ Biological imaging Hypochlorite Probe Rhodanine Yan, Jin-Long verfasserin aut Wu, Wei-Na verfasserin aut Zhao, Xiao-Lei verfasserin (orcid)0000-0002-2521-2144 aut Wang, Yuan verfasserin aut Fan, Yun-Chang verfasserin (orcid)0000-0003-4237-9242 aut Li, Xiao-Xia verfasserin aut Xu, Zhi-Hong verfasserin aut Enthalten in Journal of molecular structure New York, NY [u.a.] : Elsevier, 1967 1295 Online-Ressource (DE-627)302469745 (DE-600)1491504-2 (DE-576)255266626 0022-2860 nnns volume:1295 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.00 Chemie: Allgemeines VZ AR 1295 |
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10.1016/j.molstruc.2023.136697 doi (DE-627)ELV065232143 (ELSEVIER)S0022-2860(23)01787-8 DE-627 ger DE-627 rda eng 540 VZ 35.00 bkl Jin, Kun-Sheng verfasserin aut A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hypochlorite (ClO−) plays an important role in many cellular processes, which is proved to be related to some serious diseases. Given the electron donating and electron withdrawing properties of benzo[h]chromene and rhodanine groups, respectively, we developed a Donor (D)-p-Acceptor (A) type probe 1 for the detection of ClO− based on benzo[h]chromene (D) and rhodanine (A), whose structure was determined by ESI-MS, NMR and X-ray diffraction. Probe 1 showed a fast (within 20 s), selective and sensitive response toward ClO− via a fluorescent turn-on output. Based-on the spectral change of probe 1 induced by ClO−, the mechanism associated with oxidation breakage of rhodanine moiety was proposed. Due to the excellent biocompatibility and low cytotoxicity, probe 1 can be used for imaging of ClO− in C6 cells, Arabidopsis thaliana, and zebrafish. Benzo[ Biological imaging Hypochlorite Probe Rhodanine Yan, Jin-Long verfasserin aut Wu, Wei-Na verfasserin aut Zhao, Xiao-Lei verfasserin (orcid)0000-0002-2521-2144 aut Wang, Yuan verfasserin aut Fan, Yun-Chang verfasserin (orcid)0000-0003-4237-9242 aut Li, Xiao-Xia verfasserin aut Xu, Zhi-Hong verfasserin aut Enthalten in Journal of molecular structure New York, NY [u.a.] : Elsevier, 1967 1295 Online-Ressource (DE-627)302469745 (DE-600)1491504-2 (DE-576)255266626 0022-2860 nnns volume:1295 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.00 Chemie: Allgemeines VZ AR 1295 |
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Jin, Kun-Sheng @@aut@@ Yan, Jin-Long @@aut@@ Wu, Wei-Na @@aut@@ Zhao, Xiao-Lei @@aut@@ Wang, Yuan @@aut@@ Fan, Yun-Chang @@aut@@ Li, Xiao-Xia @@aut@@ Xu, Zhi-Hong @@aut@@ |
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Jin, Kun-Sheng |
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Jin, Kun-Sheng ddc 540 bkl 35.00 misc Benzo[ misc Biological imaging misc Hypochlorite misc Probe misc Rhodanine A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish |
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540 VZ 35.00 bkl A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish Benzo[ Biological imaging Hypochlorite Probe Rhodanine |
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A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish |
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A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish |
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Jin, Kun-Sheng Yan, Jin-Long Wu, Wei-Na Zhao, Xiao-Lei Wang, Yuan Fan, Yun-Chang Li, Xiao-Xia Xu, Zhi-Hong |
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a simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish |
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A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish |
| abstract |
Hypochlorite (ClO−) plays an important role in many cellular processes, which is proved to be related to some serious diseases. Given the electron donating and electron withdrawing properties of benzo[h]chromene and rhodanine groups, respectively, we developed a Donor (D)-p-Acceptor (A) type probe 1 for the detection of ClO− based on benzo[h]chromene (D) and rhodanine (A), whose structure was determined by ESI-MS, NMR and X-ray diffraction. Probe 1 showed a fast (within 20 s), selective and sensitive response toward ClO− via a fluorescent turn-on output. Based-on the spectral change of probe 1 induced by ClO−, the mechanism associated with oxidation breakage of rhodanine moiety was proposed. Due to the excellent biocompatibility and low cytotoxicity, probe 1 can be used for imaging of ClO− in C6 cells, Arabidopsis thaliana, and zebrafish. |
| abstractGer |
Hypochlorite (ClO−) plays an important role in many cellular processes, which is proved to be related to some serious diseases. Given the electron donating and electron withdrawing properties of benzo[h]chromene and rhodanine groups, respectively, we developed a Donor (D)-p-Acceptor (A) type probe 1 for the detection of ClO− based on benzo[h]chromene (D) and rhodanine (A), whose structure was determined by ESI-MS, NMR and X-ray diffraction. Probe 1 showed a fast (within 20 s), selective and sensitive response toward ClO− via a fluorescent turn-on output. Based-on the spectral change of probe 1 induced by ClO−, the mechanism associated with oxidation breakage of rhodanine moiety was proposed. Due to the excellent biocompatibility and low cytotoxicity, probe 1 can be used for imaging of ClO− in C6 cells, Arabidopsis thaliana, and zebrafish. |
| abstract_unstemmed |
Hypochlorite (ClO−) plays an important role in many cellular processes, which is proved to be related to some serious diseases. Given the electron donating and electron withdrawing properties of benzo[h]chromene and rhodanine groups, respectively, we developed a Donor (D)-p-Acceptor (A) type probe 1 for the detection of ClO− based on benzo[h]chromene (D) and rhodanine (A), whose structure was determined by ESI-MS, NMR and X-ray diffraction. Probe 1 showed a fast (within 20 s), selective and sensitive response toward ClO− via a fluorescent turn-on output. Based-on the spectral change of probe 1 induced by ClO−, the mechanism associated with oxidation breakage of rhodanine moiety was proposed. Due to the excellent biocompatibility and low cytotoxicity, probe 1 can be used for imaging of ClO− in C6 cells, Arabidopsis thaliana, and zebrafish. |
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A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish |
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Yan, Jin-Long Wu, Wei-Na Zhao, Xiao-Lei Wang, Yuan Fan, Yun-Chang Li, Xiao-Xia Xu, Zhi-Hong |
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