A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine

Creatinine (Cre) is a crucial biomarker in the clinical diagnosis and therapy of chronic kidney disease (CKD) and muscle diseases. Therefore, designing and developing highly sensitive, multi-signal assays for the detection of Cre is highly significant. Herein, by in situ encapsulating CdTe QDs and p...
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Autor*in:	Guan, Jianping [verfasserIn] Xiong, Yu [verfasserIn] Wang, Meng [verfasserIn] Liu, Qi [verfasserIn] Chen, Xiaoqing [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	CdTe@MOFs Biosensor Dual-Readout Assay Creatinine

Übergeordnetes Werk:	Enthalten in: Sensors and actuators / B - Amsterdam [u.a.] : Elsevier Science, 1990, 399
Übergeordnetes Werk:	volume:399

DOI / URN:	10.1016/j.snb.2023.134842

Katalog-ID:	ELV065510429

Internformat


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100	1		\|a Guan, Jianping \|e verfasserin \|4 aut
245	1	2	\|a A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine
264		1	\|c 2023
336			\|a nicht spezifiziert \|b zzz \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
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520			\|a Creatinine (Cre) is a crucial biomarker in the clinical diagnosis and therapy of chronic kidney disease (CKD) and muscle diseases. Therefore, designing and developing highly sensitive, multi-signal assays for the detection of Cre is highly significant. Herein, by in situ encapsulating CdTe QDs and post-synthetically modifying pyridine-2-carboxaldehyde (2-PC), a novel ratiometric fluorescence and colorimetric dual-signal sensor CdTeUiO-66-PC-Cu was constructed for the detection of Cre with low detection limits (LOD) 2.48 nM and 1.78 μM, respectively. Satisfactory recovery of 93.0–105.0% (RSD < 4.8%, n = 3) was also acquired for determination of Cre in actual samples. In addition, by integrating smartphone-based portable colorimetric sensing, a novel hydrogel-based colorimetric paper analytical device (c-PAD) platform was fabricated for the visual colorimetric assay of Cre in whole blood without any separation process. The dual-signal sensing system of ratiometric fluorescence and colorimetry can observably improve the sensitivity and accuracy of Cre detection. Meanwhile, this portable smartphone-integrated colorimetric sensing platform features low cost, operational simplicity, and broad adaptability, providing an ideal way to achieve point-of-care testing (POCT) of other small molecule biomarkers in human whole blood.
650		4	\|a CdTe@MOFs
650		4	\|a Biosensor
650		4	\|a Dual-Readout
650		4	\|a Assay
650		4	\|a Creatinine
700	1		\|a Xiong, Yu \|e verfasserin \|4 aut
700	1		\|a Wang, Meng \|e verfasserin \|4 aut
700	1		\|a Liu, Qi \|e verfasserin \|4 aut
700	1		\|a Chen, Xiaoqing \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Sensors and actuators <Lausanne> / B \|d Amsterdam [u.a.] : Elsevier Science, 1990 \|g 399 \|h Online-Ressource \|w (DE-627)306710358 \|w (DE-600)1500731-5 \|w (DE-576)082435855 \|x 0925-4005 \|7 nnns
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912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2026
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2059
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912			\|a GBV_ILN_4326
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912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
912			\|a GBV_ILN_4700
936	b	k	\|a 50.22 \|j Sensorik \|q VZ
936	b	k	\|a 35.07 \|j Chemisches Labor \|j chemische Methoden \|q VZ
951			\|a AR
952			\|d 399

Indexfelder

author_variant	j g jg y x yx m w mw q l ql x c xc
matchkey_str	article:09254005:2023----::nvlucinlzddeosaefurmtiadooiercisnofru
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bklnumber	50.22 35.07
publishDate	2023
allfields	10.1016/j.snb.2023.134842 doi (DE-627)ELV065510429 (ELSEVIER)S0925-4005(23)01560-5 DE-627 ger DE-627 rda eng 530 620 VZ 50.22 bkl 35.07 bkl Guan, Jianping verfasserin aut A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Creatinine (Cre) is a crucial biomarker in the clinical diagnosis and therapy of chronic kidney disease (CKD) and muscle diseases. Therefore, designing and developing highly sensitive, multi-signal assays for the detection of Cre is highly significant. Herein, by in situ encapsulating CdTe QDs and post-synthetically modifying pyridine-2-carboxaldehyde (2-PC), a novel ratiometric fluorescence and colorimetric dual-signal sensor CdTeUiO-66-PC-Cu was constructed for the detection of Cre with low detection limits (LOD) 2.48 nM and 1.78 μM, respectively. Satisfactory recovery of 93.0–105.0% (RSD < 4.8%, n = 3) was also acquired for determination of Cre in actual samples. In addition, by integrating smartphone-based portable colorimetric sensing, a novel hydrogel-based colorimetric paper analytical device (c-PAD) platform was fabricated for the visual colorimetric assay of Cre in whole blood without any separation process. The dual-signal sensing system of ratiometric fluorescence and colorimetry can observably improve the sensitivity and accuracy of Cre detection. Meanwhile, this portable smartphone-integrated colorimetric sensing platform features low cost, operational simplicity, and broad adaptability, providing an ideal way to achieve point-of-care testing (POCT) of other small molecule biomarkers in human whole blood. CdTe@MOFs Biosensor Dual-Readout Assay Creatinine Xiong, Yu verfasserin aut Wang, Meng verfasserin aut Liu, Qi verfasserin aut Chen, Xiaoqing verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 399 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:399 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 50.22 Sensorik VZ 35.07 Chemisches Labor chemische Methoden VZ AR 399
spelling	10.1016/j.snb.2023.134842 doi (DE-627)ELV065510429 (ELSEVIER)S0925-4005(23)01560-5 DE-627 ger DE-627 rda eng 530 620 VZ 50.22 bkl 35.07 bkl Guan, Jianping verfasserin aut A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Creatinine (Cre) is a crucial biomarker in the clinical diagnosis and therapy of chronic kidney disease (CKD) and muscle diseases. Therefore, designing and developing highly sensitive, multi-signal assays for the detection of Cre is highly significant. Herein, by in situ encapsulating CdTe QDs and post-synthetically modifying pyridine-2-carboxaldehyde (2-PC), a novel ratiometric fluorescence and colorimetric dual-signal sensor CdTeUiO-66-PC-Cu was constructed for the detection of Cre with low detection limits (LOD) 2.48 nM and 1.78 μM, respectively. Satisfactory recovery of 93.0–105.0% (RSD < 4.8%, n = 3) was also acquired for determination of Cre in actual samples. In addition, by integrating smartphone-based portable colorimetric sensing, a novel hydrogel-based colorimetric paper analytical device (c-PAD) platform was fabricated for the visual colorimetric assay of Cre in whole blood without any separation process. The dual-signal sensing system of ratiometric fluorescence and colorimetry can observably improve the sensitivity and accuracy of Cre detection. Meanwhile, this portable smartphone-integrated colorimetric sensing platform features low cost, operational simplicity, and broad adaptability, providing an ideal way to achieve point-of-care testing (POCT) of other small molecule biomarkers in human whole blood. CdTe@MOFs Biosensor Dual-Readout Assay Creatinine Xiong, Yu verfasserin aut Wang, Meng verfasserin aut Liu, Qi verfasserin aut Chen, Xiaoqing verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 399 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:399 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 50.22 Sensorik VZ 35.07 Chemisches Labor chemische Methoden VZ AR 399
allfields_unstemmed	10.1016/j.snb.2023.134842 doi (DE-627)ELV065510429 (ELSEVIER)S0925-4005(23)01560-5 DE-627 ger DE-627 rda eng 530 620 VZ 50.22 bkl 35.07 bkl Guan, Jianping verfasserin aut A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Creatinine (Cre) is a crucial biomarker in the clinical diagnosis and therapy of chronic kidney disease (CKD) and muscle diseases. Therefore, designing and developing highly sensitive, multi-signal assays for the detection of Cre is highly significant. Herein, by in situ encapsulating CdTe QDs and post-synthetically modifying pyridine-2-carboxaldehyde (2-PC), a novel ratiometric fluorescence and colorimetric dual-signal sensor CdTeUiO-66-PC-Cu was constructed for the detection of Cre with low detection limits (LOD) 2.48 nM and 1.78 μM, respectively. Satisfactory recovery of 93.0–105.0% (RSD < 4.8%, n = 3) was also acquired for determination of Cre in actual samples. In addition, by integrating smartphone-based portable colorimetric sensing, a novel hydrogel-based colorimetric paper analytical device (c-PAD) platform was fabricated for the visual colorimetric assay of Cre in whole blood without any separation process. The dual-signal sensing system of ratiometric fluorescence and colorimetry can observably improve the sensitivity and accuracy of Cre detection. Meanwhile, this portable smartphone-integrated colorimetric sensing platform features low cost, operational simplicity, and broad adaptability, providing an ideal way to achieve point-of-care testing (POCT) of other small molecule biomarkers in human whole blood. CdTe@MOFs Biosensor Dual-Readout Assay Creatinine Xiong, Yu verfasserin aut Wang, Meng verfasserin aut Liu, Qi verfasserin aut Chen, Xiaoqing verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 399 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:399 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 50.22 Sensorik VZ 35.07 Chemisches Labor chemische Methoden VZ AR 399
allfieldsGer	10.1016/j.snb.2023.134842 doi (DE-627)ELV065510429 (ELSEVIER)S0925-4005(23)01560-5 DE-627 ger DE-627 rda eng 530 620 VZ 50.22 bkl 35.07 bkl Guan, Jianping verfasserin aut A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Creatinine (Cre) is a crucial biomarker in the clinical diagnosis and therapy of chronic kidney disease (CKD) and muscle diseases. Therefore, designing and developing highly sensitive, multi-signal assays for the detection of Cre is highly significant. Herein, by in situ encapsulating CdTe QDs and post-synthetically modifying pyridine-2-carboxaldehyde (2-PC), a novel ratiometric fluorescence and colorimetric dual-signal sensor CdTeUiO-66-PC-Cu was constructed for the detection of Cre with low detection limits (LOD) 2.48 nM and 1.78 μM, respectively. Satisfactory recovery of 93.0–105.0% (RSD < 4.8%, n = 3) was also acquired for determination of Cre in actual samples. In addition, by integrating smartphone-based portable colorimetric sensing, a novel hydrogel-based colorimetric paper analytical device (c-PAD) platform was fabricated for the visual colorimetric assay of Cre in whole blood without any separation process. The dual-signal sensing system of ratiometric fluorescence and colorimetry can observably improve the sensitivity and accuracy of Cre detection. Meanwhile, this portable smartphone-integrated colorimetric sensing platform features low cost, operational simplicity, and broad adaptability, providing an ideal way to achieve point-of-care testing (POCT) of other small molecule biomarkers in human whole blood. CdTe@MOFs Biosensor Dual-Readout Assay Creatinine Xiong, Yu verfasserin aut Wang, Meng verfasserin aut Liu, Qi verfasserin aut Chen, Xiaoqing verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 399 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:399 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 50.22 Sensorik VZ 35.07 Chemisches Labor chemische Methoden VZ AR 399
allfieldsSound	10.1016/j.snb.2023.134842 doi (DE-627)ELV065510429 (ELSEVIER)S0925-4005(23)01560-5 DE-627 ger DE-627 rda eng 530 620 VZ 50.22 bkl 35.07 bkl Guan, Jianping verfasserin aut A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Creatinine (Cre) is a crucial biomarker in the clinical diagnosis and therapy of chronic kidney disease (CKD) and muscle diseases. Therefore, designing and developing highly sensitive, multi-signal assays for the detection of Cre is highly significant. Herein, by in situ encapsulating CdTe QDs and post-synthetically modifying pyridine-2-carboxaldehyde (2-PC), a novel ratiometric fluorescence and colorimetric dual-signal sensor CdTeUiO-66-PC-Cu was constructed for the detection of Cre with low detection limits (LOD) 2.48 nM and 1.78 μM, respectively. Satisfactory recovery of 93.0–105.0% (RSD < 4.8%, n = 3) was also acquired for determination of Cre in actual samples. In addition, by integrating smartphone-based portable colorimetric sensing, a novel hydrogel-based colorimetric paper analytical device (c-PAD) platform was fabricated for the visual colorimetric assay of Cre in whole blood without any separation process. The dual-signal sensing system of ratiometric fluorescence and colorimetry can observably improve the sensitivity and accuracy of Cre detection. Meanwhile, this portable smartphone-integrated colorimetric sensing platform features low cost, operational simplicity, and broad adaptability, providing an ideal way to achieve point-of-care testing (POCT) of other small molecule biomarkers in human whole blood. CdTe@MOFs Biosensor Dual-Readout Assay Creatinine Xiong, Yu verfasserin aut Wang, Meng verfasserin aut Liu, Qi verfasserin aut Chen, Xiaoqing verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 399 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:399 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 50.22 Sensorik VZ 35.07 Chemisches Labor chemische Methoden VZ AR 399
language	English
source	Enthalten in Sensors and actuators <Lausanne> / B 399 volume:399
sourceStr	Enthalten in Sensors and actuators <Lausanne> / B 399 volume:399
format_phy_str_mv	Article
bklname	Sensorik Chemisches Labor chemische Methoden
institution	findex.gbv.de
topic_facet	CdTe@MOFs Biosensor Dual-Readout Assay Creatinine
dewey-raw	530
isfreeaccess_bool	false
container_title	Sensors and actuators <Lausanne> / B
authorswithroles_txt_mv	Guan, Jianping @@aut@@ Xiong, Yu @@aut@@ Wang, Meng @@aut@@ Liu, Qi @@aut@@ Chen, Xiaoqing @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	306710358
dewey-sort	3530
id	ELV065510429
language_de	englisch
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author	Guan, Jianping
spellingShingle	Guan, Jianping ddc 530 bkl 50.22 bkl 35.07 misc CdTe@MOFs misc Biosensor misc Dual-Readout misc Assay misc Creatinine A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine
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topic_title	530 620 VZ 50.22 bkl 35.07 bkl A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine CdTe@MOFs Biosensor Dual-Readout Assay Creatinine
topic	ddc 530 bkl 50.22 bkl 35.07 misc CdTe@MOFs misc Biosensor misc Dual-Readout misc Assay misc Creatinine
topic_unstemmed	ddc 530 bkl 50.22 bkl 35.07 misc CdTe@MOFs misc Biosensor misc Dual-Readout misc Assay misc Creatinine
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title	A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine
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title_full	A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine
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author_browse	Guan, Jianping Xiong, Yu Wang, Meng Liu, Qi Chen, Xiaoqing
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title_sort	novel functionalized cdtemofs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine
title_auth	A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine
abstract	Creatinine (Cre) is a crucial biomarker in the clinical diagnosis and therapy of chronic kidney disease (CKD) and muscle diseases. Therefore, designing and developing highly sensitive, multi-signal assays for the detection of Cre is highly significant. Herein, by in situ encapsulating CdTe QDs and post-synthetically modifying pyridine-2-carboxaldehyde (2-PC), a novel ratiometric fluorescence and colorimetric dual-signal sensor CdTeUiO-66-PC-Cu was constructed for the detection of Cre with low detection limits (LOD) 2.48 nM and 1.78 μM, respectively. Satisfactory recovery of 93.0–105.0% (RSD < 4.8%, n = 3) was also acquired for determination of Cre in actual samples. In addition, by integrating smartphone-based portable colorimetric sensing, a novel hydrogel-based colorimetric paper analytical device (c-PAD) platform was fabricated for the visual colorimetric assay of Cre in whole blood without any separation process. The dual-signal sensing system of ratiometric fluorescence and colorimetry can observably improve the sensitivity and accuracy of Cre detection. Meanwhile, this portable smartphone-integrated colorimetric sensing platform features low cost, operational simplicity, and broad adaptability, providing an ideal way to achieve point-of-care testing (POCT) of other small molecule biomarkers in human whole blood.
abstractGer	Creatinine (Cre) is a crucial biomarker in the clinical diagnosis and therapy of chronic kidney disease (CKD) and muscle diseases. Therefore, designing and developing highly sensitive, multi-signal assays for the detection of Cre is highly significant. Herein, by in situ encapsulating CdTe QDs and post-synthetically modifying pyridine-2-carboxaldehyde (2-PC), a novel ratiometric fluorescence and colorimetric dual-signal sensor CdTeUiO-66-PC-Cu was constructed for the detection of Cre with low detection limits (LOD) 2.48 nM and 1.78 μM, respectively. Satisfactory recovery of 93.0–105.0% (RSD < 4.8%, n = 3) was also acquired for determination of Cre in actual samples. In addition, by integrating smartphone-based portable colorimetric sensing, a novel hydrogel-based colorimetric paper analytical device (c-PAD) platform was fabricated for the visual colorimetric assay of Cre in whole blood without any separation process. The dual-signal sensing system of ratiometric fluorescence and colorimetry can observably improve the sensitivity and accuracy of Cre detection. Meanwhile, this portable smartphone-integrated colorimetric sensing platform features low cost, operational simplicity, and broad adaptability, providing an ideal way to achieve point-of-care testing (POCT) of other small molecule biomarkers in human whole blood.
abstract_unstemmed	Creatinine (Cre) is a crucial biomarker in the clinical diagnosis and therapy of chronic kidney disease (CKD) and muscle diseases. Therefore, designing and developing highly sensitive, multi-signal assays for the detection of Cre is highly significant. Herein, by in situ encapsulating CdTe QDs and post-synthetically modifying pyridine-2-carboxaldehyde (2-PC), a novel ratiometric fluorescence and colorimetric dual-signal sensor CdTeUiO-66-PC-Cu was constructed for the detection of Cre with low detection limits (LOD) 2.48 nM and 1.78 μM, respectively. Satisfactory recovery of 93.0–105.0% (RSD < 4.8%, n = 3) was also acquired for determination of Cre in actual samples. In addition, by integrating smartphone-based portable colorimetric sensing, a novel hydrogel-based colorimetric paper analytical device (c-PAD) platform was fabricated for the visual colorimetric assay of Cre in whole blood without any separation process. The dual-signal sensing system of ratiometric fluorescence and colorimetry can observably improve the sensitivity and accuracy of Cre detection. Meanwhile, this portable smartphone-integrated colorimetric sensing platform features low cost, operational simplicity, and broad adaptability, providing an ideal way to achieve point-of-care testing (POCT) of other small molecule biomarkers in human whole blood.
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title_short	A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine
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author2	Xiong, Yu Wang, Meng Liu, Qi Chen, Xiaoqing
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up_date	2024-07-06T23:16:57.242Z
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A novel functionalized CdTeMOFs based fluorometric and colorimetric biosensor for dual-readout assay of creatinine

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