Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence
A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little is known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health cont...
Ausführliche Beschreibung
Autor*in: |
Li, Yu-Ting [verfasserIn] Bai, Ke [verfasserIn] Li, Gan-Ze [verfasserIn] Hu, Bo [verfasserIn] Chen, Jia-Wei [verfasserIn] Shang, Yu-Xuan [verfasserIn] Yu, Ying [verfasserIn] Chen, Zhu-Hong [verfasserIn] Zhang, Chi [verfasserIn] Yan, Lin-Feng [verfasserIn] Cui, Guang-Bin [verfasserIn] Lu, Lian-Jun [verfasserIn] Wang, Wen [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2023 |
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Schlagwörter: |
sudden sensorineural hearing loss (SSNHL) |
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Übergeordnetes Werk: |
Enthalten in: NeuroImage - Orlando, Fla. : Academic Press, 1992, 283 |
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Übergeordnetes Werk: |
volume:283 |
DOI / URN: |
10.1016/j.neuroimage.2023.120437 |
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Katalog-ID: |
ELV065587197 |
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245 | 1 | 0 | |a Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence |
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520 | |a A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little is known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health controls (HC), followed by comprehensive neuroimaging analyses. The primary outcome measures were temporal alterations of varied dynamic functional network connectivity (dFNC) states, neurovascular coupling (NVC) and brain region volume at different stages of SSNHL. The secondary outcome measures were pure-tone audiograms of SSNHL patients before and after treatment. A total of 38 SSNHL patients (21 [55%] male; mean [standard deviation] age, 45.05 [15.83] years) and 44 HC (28 [64%] male; mean [standard deviation] age, 43.55 [12.80] years) were enrolled. SSNHL patients were categorized into subgroups based on the time from disease onset to the initial magnetic resonance imaging scan: early- (n = 16; 1-6 days), intermediate- (n = 9; 7-13 days), and late- stage (n = 13; 14-30 days) groups. We first identified slow state transitions between varied dFNC states at early-stage SSNHL, then revealed the decreased NVC restricted to the auditory cortex at the intermediate- and late-stage SSNHL. Finally, a significantly decreased volume of the left medial superior frontal gyrus (SFGmed) was observed only in the late-stage SSNHL cohort. Furthermore, the volume of the left SFGmed is robustly correlated with both disease duration and patient prognosis. Our study offered neuroimaging evidence for the evolvement from functional to structural brain alterations of SSNHL patients with disease duration less than 1 month, which may explain, from a neuroimaging perspective, why early-stage SSNHL patients have better therapeutic responses and hearing recovery. | ||
650 | 4 | |a sudden sensorineural hearing loss (SSNHL) | |
650 | 4 | |a cortical plasticity | |
650 | 4 | |a dynamic functional network connectivity (dFNC) | |
650 | 4 | |a neurovascular coupling (NVC) | |
650 | 4 | |a voxel-based morphometry (VBM) analysis | |
700 | 1 | |a Bai, Ke |e verfasserin |4 aut | |
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700 | 1 | |a Cui, Guang-Bin |e verfasserin |4 aut | |
700 | 1 | |a Lu, Lian-Jun |e verfasserin |4 aut | |
700 | 1 | |a Wang, Wen |e verfasserin |0 (orcid)0000-0001-6473-4888 |4 aut | |
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10.1016/j.neuroimage.2023.120437 doi (DE-627)ELV065587197 (ELSEVIER)S1053-8119(23)00588-8 DE-627 ger DE-627 rda eng 610 VZ LING DE-30 fid 44.64 bkl 44.90 bkl Li, Yu-Ting verfasserin aut Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little is known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health controls (HC), followed by comprehensive neuroimaging analyses. The primary outcome measures were temporal alterations of varied dynamic functional network connectivity (dFNC) states, neurovascular coupling (NVC) and brain region volume at different stages of SSNHL. The secondary outcome measures were pure-tone audiograms of SSNHL patients before and after treatment. A total of 38 SSNHL patients (21 [55%] male; mean [standard deviation] age, 45.05 [15.83] years) and 44 HC (28 [64%] male; mean [standard deviation] age, 43.55 [12.80] years) were enrolled. SSNHL patients were categorized into subgroups based on the time from disease onset to the initial magnetic resonance imaging scan: early- (n = 16; 1-6 days), intermediate- (n = 9; 7-13 days), and late- stage (n = 13; 14-30 days) groups. We first identified slow state transitions between varied dFNC states at early-stage SSNHL, then revealed the decreased NVC restricted to the auditory cortex at the intermediate- and late-stage SSNHL. Finally, a significantly decreased volume of the left medial superior frontal gyrus (SFGmed) was observed only in the late-stage SSNHL cohort. Furthermore, the volume of the left SFGmed is robustly correlated with both disease duration and patient prognosis. Our study offered neuroimaging evidence for the evolvement from functional to structural brain alterations of SSNHL patients with disease duration less than 1 month, which may explain, from a neuroimaging perspective, why early-stage SSNHL patients have better therapeutic responses and hearing recovery. sudden sensorineural hearing loss (SSNHL) cortical plasticity dynamic functional network connectivity (dFNC) neurovascular coupling (NVC) voxel-based morphometry (VBM) analysis Bai, Ke verfasserin aut Li, Gan-Ze verfasserin aut Hu, Bo verfasserin aut Chen, Jia-Wei verfasserin aut Shang, Yu-Xuan verfasserin aut Yu, Ying verfasserin aut Chen, Zhu-Hong verfasserin aut Zhang, Chi verfasserin aut Yan, Lin-Feng verfasserin aut Cui, Guang-Bin verfasserin aut Lu, Lian-Jun verfasserin aut Wang, Wen verfasserin (orcid)0000-0001-6473-4888 aut Enthalten in NeuroImage Orlando, Fla. : Academic Press, 1992 283 Online-Ressource (DE-627)268125503 (DE-600)1471418-8 (DE-576)106869507 1095-9572 nnns volume:283 GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2014 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.64 Radiologie VZ 44.90 Neurologie VZ AR 283 |
spelling |
10.1016/j.neuroimage.2023.120437 doi (DE-627)ELV065587197 (ELSEVIER)S1053-8119(23)00588-8 DE-627 ger DE-627 rda eng 610 VZ LING DE-30 fid 44.64 bkl 44.90 bkl Li, Yu-Ting verfasserin aut Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little is known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health controls (HC), followed by comprehensive neuroimaging analyses. The primary outcome measures were temporal alterations of varied dynamic functional network connectivity (dFNC) states, neurovascular coupling (NVC) and brain region volume at different stages of SSNHL. The secondary outcome measures were pure-tone audiograms of SSNHL patients before and after treatment. A total of 38 SSNHL patients (21 [55%] male; mean [standard deviation] age, 45.05 [15.83] years) and 44 HC (28 [64%] male; mean [standard deviation] age, 43.55 [12.80] years) were enrolled. SSNHL patients were categorized into subgroups based on the time from disease onset to the initial magnetic resonance imaging scan: early- (n = 16; 1-6 days), intermediate- (n = 9; 7-13 days), and late- stage (n = 13; 14-30 days) groups. We first identified slow state transitions between varied dFNC states at early-stage SSNHL, then revealed the decreased NVC restricted to the auditory cortex at the intermediate- and late-stage SSNHL. Finally, a significantly decreased volume of the left medial superior frontal gyrus (SFGmed) was observed only in the late-stage SSNHL cohort. Furthermore, the volume of the left SFGmed is robustly correlated with both disease duration and patient prognosis. Our study offered neuroimaging evidence for the evolvement from functional to structural brain alterations of SSNHL patients with disease duration less than 1 month, which may explain, from a neuroimaging perspective, why early-stage SSNHL patients have better therapeutic responses and hearing recovery. sudden sensorineural hearing loss (SSNHL) cortical plasticity dynamic functional network connectivity (dFNC) neurovascular coupling (NVC) voxel-based morphometry (VBM) analysis Bai, Ke verfasserin aut Li, Gan-Ze verfasserin aut Hu, Bo verfasserin aut Chen, Jia-Wei verfasserin aut Shang, Yu-Xuan verfasserin aut Yu, Ying verfasserin aut Chen, Zhu-Hong verfasserin aut Zhang, Chi verfasserin aut Yan, Lin-Feng verfasserin aut Cui, Guang-Bin verfasserin aut Lu, Lian-Jun verfasserin aut Wang, Wen verfasserin (orcid)0000-0001-6473-4888 aut Enthalten in NeuroImage Orlando, Fla. : Academic Press, 1992 283 Online-Ressource (DE-627)268125503 (DE-600)1471418-8 (DE-576)106869507 1095-9572 nnns volume:283 GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2014 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.64 Radiologie VZ 44.90 Neurologie VZ AR 283 |
allfields_unstemmed |
10.1016/j.neuroimage.2023.120437 doi (DE-627)ELV065587197 (ELSEVIER)S1053-8119(23)00588-8 DE-627 ger DE-627 rda eng 610 VZ LING DE-30 fid 44.64 bkl 44.90 bkl Li, Yu-Ting verfasserin aut Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little is known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health controls (HC), followed by comprehensive neuroimaging analyses. The primary outcome measures were temporal alterations of varied dynamic functional network connectivity (dFNC) states, neurovascular coupling (NVC) and brain region volume at different stages of SSNHL. The secondary outcome measures were pure-tone audiograms of SSNHL patients before and after treatment. A total of 38 SSNHL patients (21 [55%] male; mean [standard deviation] age, 45.05 [15.83] years) and 44 HC (28 [64%] male; mean [standard deviation] age, 43.55 [12.80] years) were enrolled. SSNHL patients were categorized into subgroups based on the time from disease onset to the initial magnetic resonance imaging scan: early- (n = 16; 1-6 days), intermediate- (n = 9; 7-13 days), and late- stage (n = 13; 14-30 days) groups. We first identified slow state transitions between varied dFNC states at early-stage SSNHL, then revealed the decreased NVC restricted to the auditory cortex at the intermediate- and late-stage SSNHL. Finally, a significantly decreased volume of the left medial superior frontal gyrus (SFGmed) was observed only in the late-stage SSNHL cohort. Furthermore, the volume of the left SFGmed is robustly correlated with both disease duration and patient prognosis. Our study offered neuroimaging evidence for the evolvement from functional to structural brain alterations of SSNHL patients with disease duration less than 1 month, which may explain, from a neuroimaging perspective, why early-stage SSNHL patients have better therapeutic responses and hearing recovery. sudden sensorineural hearing loss (SSNHL) cortical plasticity dynamic functional network connectivity (dFNC) neurovascular coupling (NVC) voxel-based morphometry (VBM) analysis Bai, Ke verfasserin aut Li, Gan-Ze verfasserin aut Hu, Bo verfasserin aut Chen, Jia-Wei verfasserin aut Shang, Yu-Xuan verfasserin aut Yu, Ying verfasserin aut Chen, Zhu-Hong verfasserin aut Zhang, Chi verfasserin aut Yan, Lin-Feng verfasserin aut Cui, Guang-Bin verfasserin aut Lu, Lian-Jun verfasserin aut Wang, Wen verfasserin (orcid)0000-0001-6473-4888 aut Enthalten in NeuroImage Orlando, Fla. : Academic Press, 1992 283 Online-Ressource (DE-627)268125503 (DE-600)1471418-8 (DE-576)106869507 1095-9572 nnns volume:283 GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2014 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.64 Radiologie VZ 44.90 Neurologie VZ AR 283 |
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10.1016/j.neuroimage.2023.120437 doi (DE-627)ELV065587197 (ELSEVIER)S1053-8119(23)00588-8 DE-627 ger DE-627 rda eng 610 VZ LING DE-30 fid 44.64 bkl 44.90 bkl Li, Yu-Ting verfasserin aut Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little is known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health controls (HC), followed by comprehensive neuroimaging analyses. The primary outcome measures were temporal alterations of varied dynamic functional network connectivity (dFNC) states, neurovascular coupling (NVC) and brain region volume at different stages of SSNHL. The secondary outcome measures were pure-tone audiograms of SSNHL patients before and after treatment. A total of 38 SSNHL patients (21 [55%] male; mean [standard deviation] age, 45.05 [15.83] years) and 44 HC (28 [64%] male; mean [standard deviation] age, 43.55 [12.80] years) were enrolled. SSNHL patients were categorized into subgroups based on the time from disease onset to the initial magnetic resonance imaging scan: early- (n = 16; 1-6 days), intermediate- (n = 9; 7-13 days), and late- stage (n = 13; 14-30 days) groups. We first identified slow state transitions between varied dFNC states at early-stage SSNHL, then revealed the decreased NVC restricted to the auditory cortex at the intermediate- and late-stage SSNHL. Finally, a significantly decreased volume of the left medial superior frontal gyrus (SFGmed) was observed only in the late-stage SSNHL cohort. Furthermore, the volume of the left SFGmed is robustly correlated with both disease duration and patient prognosis. Our study offered neuroimaging evidence for the evolvement from functional to structural brain alterations of SSNHL patients with disease duration less than 1 month, which may explain, from a neuroimaging perspective, why early-stage SSNHL patients have better therapeutic responses and hearing recovery. sudden sensorineural hearing loss (SSNHL) cortical plasticity dynamic functional network connectivity (dFNC) neurovascular coupling (NVC) voxel-based morphometry (VBM) analysis Bai, Ke verfasserin aut Li, Gan-Ze verfasserin aut Hu, Bo verfasserin aut Chen, Jia-Wei verfasserin aut Shang, Yu-Xuan verfasserin aut Yu, Ying verfasserin aut Chen, Zhu-Hong verfasserin aut Zhang, Chi verfasserin aut Yan, Lin-Feng verfasserin aut Cui, Guang-Bin verfasserin aut Lu, Lian-Jun verfasserin aut Wang, Wen verfasserin (orcid)0000-0001-6473-4888 aut Enthalten in NeuroImage Orlando, Fla. : Academic Press, 1992 283 Online-Ressource (DE-627)268125503 (DE-600)1471418-8 (DE-576)106869507 1095-9572 nnns volume:283 GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2014 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.64 Radiologie VZ 44.90 Neurologie VZ AR 283 |
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10.1016/j.neuroimage.2023.120437 doi (DE-627)ELV065587197 (ELSEVIER)S1053-8119(23)00588-8 DE-627 ger DE-627 rda eng 610 VZ LING DE-30 fid 44.64 bkl 44.90 bkl Li, Yu-Ting verfasserin aut Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little is known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health controls (HC), followed by comprehensive neuroimaging analyses. The primary outcome measures were temporal alterations of varied dynamic functional network connectivity (dFNC) states, neurovascular coupling (NVC) and brain region volume at different stages of SSNHL. The secondary outcome measures were pure-tone audiograms of SSNHL patients before and after treatment. A total of 38 SSNHL patients (21 [55%] male; mean [standard deviation] age, 45.05 [15.83] years) and 44 HC (28 [64%] male; mean [standard deviation] age, 43.55 [12.80] years) were enrolled. SSNHL patients were categorized into subgroups based on the time from disease onset to the initial magnetic resonance imaging scan: early- (n = 16; 1-6 days), intermediate- (n = 9; 7-13 days), and late- stage (n = 13; 14-30 days) groups. We first identified slow state transitions between varied dFNC states at early-stage SSNHL, then revealed the decreased NVC restricted to the auditory cortex at the intermediate- and late-stage SSNHL. Finally, a significantly decreased volume of the left medial superior frontal gyrus (SFGmed) was observed only in the late-stage SSNHL cohort. Furthermore, the volume of the left SFGmed is robustly correlated with both disease duration and patient prognosis. Our study offered neuroimaging evidence for the evolvement from functional to structural brain alterations of SSNHL patients with disease duration less than 1 month, which may explain, from a neuroimaging perspective, why early-stage SSNHL patients have better therapeutic responses and hearing recovery. sudden sensorineural hearing loss (SSNHL) cortical plasticity dynamic functional network connectivity (dFNC) neurovascular coupling (NVC) voxel-based morphometry (VBM) analysis Bai, Ke verfasserin aut Li, Gan-Ze verfasserin aut Hu, Bo verfasserin aut Chen, Jia-Wei verfasserin aut Shang, Yu-Xuan verfasserin aut Yu, Ying verfasserin aut Chen, Zhu-Hong verfasserin aut Zhang, Chi verfasserin aut Yan, Lin-Feng verfasserin aut Cui, Guang-Bin verfasserin aut Lu, Lian-Jun verfasserin aut Wang, Wen verfasserin (orcid)0000-0001-6473-4888 aut Enthalten in NeuroImage Orlando, Fla. : Academic Press, 1992 283 Online-Ressource (DE-627)268125503 (DE-600)1471418-8 (DE-576)106869507 1095-9572 nnns volume:283 GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2014 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.64 Radiologie VZ 44.90 Neurologie VZ AR 283 |
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topic_facet |
sudden sensorineural hearing loss (SSNHL) cortical plasticity dynamic functional network connectivity (dFNC) neurovascular coupling (NVC) voxel-based morphometry (VBM) analysis |
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Li, Yu-Ting @@aut@@ Bai, Ke @@aut@@ Li, Gan-Ze @@aut@@ Hu, Bo @@aut@@ Chen, Jia-Wei @@aut@@ Shang, Yu-Xuan @@aut@@ Yu, Ying @@aut@@ Chen, Zhu-Hong @@aut@@ Zhang, Chi @@aut@@ Yan, Lin-Feng @@aut@@ Cui, Guang-Bin @@aut@@ Lu, Lian-Jun @@aut@@ Wang, Wen @@aut@@ |
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2023-01-01T00:00:00Z |
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Li, Yu-Ting |
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Li, Yu-Ting ddc 610 fid LING bkl 44.64 bkl 44.90 misc sudden sensorineural hearing loss (SSNHL) misc cortical plasticity misc dynamic functional network connectivity (dFNC) misc neurovascular coupling (NVC) misc voxel-based morphometry (VBM) analysis Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence |
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610 VZ LING DE-30 fid 44.64 bkl 44.90 bkl Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence sudden sensorineural hearing loss (SSNHL) cortical plasticity dynamic functional network connectivity (dFNC) neurovascular coupling (NVC) voxel-based morphometry (VBM) analysis |
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ddc 610 fid LING bkl 44.64 bkl 44.90 misc sudden sensorineural hearing loss (SSNHL) misc cortical plasticity misc dynamic functional network connectivity (dFNC) misc neurovascular coupling (NVC) misc voxel-based morphometry (VBM) analysis |
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Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence |
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Li, Yu-Ting Bai, Ke Li, Gan-Ze Hu, Bo Chen, Jia-Wei Shang, Yu-Xuan Yu, Ying Chen, Zhu-Hong Zhang, Chi Yan, Lin-Feng Cui, Guang-Bin Lu, Lian-Jun Wang, Wen |
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functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence |
title_auth |
Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence |
abstract |
A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little is known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health controls (HC), followed by comprehensive neuroimaging analyses. The primary outcome measures were temporal alterations of varied dynamic functional network connectivity (dFNC) states, neurovascular coupling (NVC) and brain region volume at different stages of SSNHL. The secondary outcome measures were pure-tone audiograms of SSNHL patients before and after treatment. A total of 38 SSNHL patients (21 [55%] male; mean [standard deviation] age, 45.05 [15.83] years) and 44 HC (28 [64%] male; mean [standard deviation] age, 43.55 [12.80] years) were enrolled. SSNHL patients were categorized into subgroups based on the time from disease onset to the initial magnetic resonance imaging scan: early- (n = 16; 1-6 days), intermediate- (n = 9; 7-13 days), and late- stage (n = 13; 14-30 days) groups. We first identified slow state transitions between varied dFNC states at early-stage SSNHL, then revealed the decreased NVC restricted to the auditory cortex at the intermediate- and late-stage SSNHL. Finally, a significantly decreased volume of the left medial superior frontal gyrus (SFGmed) was observed only in the late-stage SSNHL cohort. Furthermore, the volume of the left SFGmed is robustly correlated with both disease duration and patient prognosis. Our study offered neuroimaging evidence for the evolvement from functional to structural brain alterations of SSNHL patients with disease duration less than 1 month, which may explain, from a neuroimaging perspective, why early-stage SSNHL patients have better therapeutic responses and hearing recovery. |
abstractGer |
A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little is known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health controls (HC), followed by comprehensive neuroimaging analyses. The primary outcome measures were temporal alterations of varied dynamic functional network connectivity (dFNC) states, neurovascular coupling (NVC) and brain region volume at different stages of SSNHL. The secondary outcome measures were pure-tone audiograms of SSNHL patients before and after treatment. A total of 38 SSNHL patients (21 [55%] male; mean [standard deviation] age, 45.05 [15.83] years) and 44 HC (28 [64%] male; mean [standard deviation] age, 43.55 [12.80] years) were enrolled. SSNHL patients were categorized into subgroups based on the time from disease onset to the initial magnetic resonance imaging scan: early- (n = 16; 1-6 days), intermediate- (n = 9; 7-13 days), and late- stage (n = 13; 14-30 days) groups. We first identified slow state transitions between varied dFNC states at early-stage SSNHL, then revealed the decreased NVC restricted to the auditory cortex at the intermediate- and late-stage SSNHL. Finally, a significantly decreased volume of the left medial superior frontal gyrus (SFGmed) was observed only in the late-stage SSNHL cohort. Furthermore, the volume of the left SFGmed is robustly correlated with both disease duration and patient prognosis. Our study offered neuroimaging evidence for the evolvement from functional to structural brain alterations of SSNHL patients with disease duration less than 1 month, which may explain, from a neuroimaging perspective, why early-stage SSNHL patients have better therapeutic responses and hearing recovery. |
abstract_unstemmed |
A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little is known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health controls (HC), followed by comprehensive neuroimaging analyses. The primary outcome measures were temporal alterations of varied dynamic functional network connectivity (dFNC) states, neurovascular coupling (NVC) and brain region volume at different stages of SSNHL. The secondary outcome measures were pure-tone audiograms of SSNHL patients before and after treatment. A total of 38 SSNHL patients (21 [55%] male; mean [standard deviation] age, 45.05 [15.83] years) and 44 HC (28 [64%] male; mean [standard deviation] age, 43.55 [12.80] years) were enrolled. SSNHL patients were categorized into subgroups based on the time from disease onset to the initial magnetic resonance imaging scan: early- (n = 16; 1-6 days), intermediate- (n = 9; 7-13 days), and late- stage (n = 13; 14-30 days) groups. We first identified slow state transitions between varied dFNC states at early-stage SSNHL, then revealed the decreased NVC restricted to the auditory cortex at the intermediate- and late-stage SSNHL. Finally, a significantly decreased volume of the left medial superior frontal gyrus (SFGmed) was observed only in the late-stage SSNHL cohort. Furthermore, the volume of the left SFGmed is robustly correlated with both disease duration and patient prognosis. Our study offered neuroimaging evidence for the evolvement from functional to structural brain alterations of SSNHL patients with disease duration less than 1 month, which may explain, from a neuroimaging perspective, why early-stage SSNHL patients have better therapeutic responses and hearing recovery. |
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title_short |
Functional to structural plasticity in unilateral sudden sensorineural hearing loss: neuroimaging evidence |
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Bai, Ke Li, Gan-Ze Hu, Bo Chen, Jia-Wei Shang, Yu-Xuan Yu, Ying Chen, Zhu-Hong Zhang, Chi Yan, Lin-Feng Cui, Guang-Bin Lu, Lian-Jun Wang, Wen |
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7.4003687 |