Discovery of imidazopyridine-pyrazoline-hybrid structure as SHP-1 agonist that suppresses phospho-STAT3 signaling in human breast cancer cells

Signal transducer and activator of transcription 3 (STAT3) promotes breast cancer malignancy and controls key processes including proliferation, differentiation, and survival in breast cancer cells. Although many methods for treating breast cancer have been improved, there is still a need to discove...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Yang, Min Hee [verfasserIn]

Sethi, Gautam [verfasserIn]

Ravish, Akshay [verfasserIn]

Mohan, Arun Kumar [verfasserIn]

Pandey, Vijay [verfasserIn]

Lobie, Peter E. [verfasserIn]

Basappa, Shreeja [verfasserIn]

Basappa, Basappa [verfasserIn]

Ahn, Kwang Seok [verfasserIn]

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2023

Schlagwörter:

DIP

STAT3

Apoptosis

Breast cancer

Docetaxel

Übergeordnetes Werk:

Enthalten in: Chemico-biological interactions - Amsterdam [u.a.] : Elsevier Science, 1969, 386

Übergeordnetes Werk:

volume:386

DOI / URN:

10.1016/j.cbi.2023.110780

Katalog-ID:

ELV065595084

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