Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy

Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Scott, Hayden [verfasserIn] Alvarez, Paola [verfasserIn] Howell, Rebecca [verfasserIn] Riegel, Adam [verfasserIn] Sun, Ryan [verfasserIn] Kry, Stephen [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2024

Schlagwörter:	OSLD Quality assurance Dose limit

Übergeordnetes Werk:	Enthalten in: Radiation measurements - Amsterdam [u.a.] : Elsevier Science, 1994, 171
Übergeordnetes Werk:	volume:171

DOI / URN:	10.1016/j.radmeas.2024.107063

Katalog-ID:	ELV066972043

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520			\|a Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs.
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650		4	\|a Quality assurance
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700	1		\|a Alvarez, Paola \|e verfasserin \|4 aut
700	1		\|a Howell, Rebecca \|e verfasserin \|4 aut
700	1		\|a Riegel, Adam \|e verfasserin \|4 aut
700	1		\|a Sun, Ryan \|e verfasserin \|4 aut
700	1		\|a Kry, Stephen \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Radiation measurements \|d Amsterdam [u.a.] : Elsevier Science, 1994 \|g 171 \|h Online-Ressource \|w (DE-627)32040661X \|w (DE-600)2000759-0 \|w (DE-576)259484393 \|x 1350-4487 \|7 nnns
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allfields	10.1016/j.radmeas.2024.107063 doi (DE-627)ELV066972043 (ELSEVIER)S1350-4487(24)00011-8 DE-627 ger DE-627 rda eng 530 VZ 33.40 bkl 42.14 bkl 44.64 bkl Scott, Hayden verfasserin (orcid)0000-0003-1066-1999 aut Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy 2024 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs. OSLD Quality assurance Dose limit Alvarez, Paola verfasserin aut Howell, Rebecca verfasserin aut Riegel, Adam verfasserin aut Sun, Ryan verfasserin aut Kry, Stephen verfasserin aut Enthalten in Radiation measurements Amsterdam [u.a.] : Elsevier Science, 1994 171 Online-Ressource (DE-627)32040661X (DE-600)2000759-0 (DE-576)259484393 1350-4487 nnns volume:171 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2360 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 33.40 Kernphysik VZ 42.14 Strahlenbiologie VZ 44.64 Radiologie VZ AR 171
spelling	10.1016/j.radmeas.2024.107063 doi (DE-627)ELV066972043 (ELSEVIER)S1350-4487(24)00011-8 DE-627 ger DE-627 rda eng 530 VZ 33.40 bkl 42.14 bkl 44.64 bkl Scott, Hayden verfasserin (orcid)0000-0003-1066-1999 aut Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy 2024 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs. OSLD Quality assurance Dose limit Alvarez, Paola verfasserin aut Howell, Rebecca verfasserin aut Riegel, Adam verfasserin aut Sun, Ryan verfasserin aut Kry, Stephen verfasserin aut Enthalten in Radiation measurements Amsterdam [u.a.] : Elsevier Science, 1994 171 Online-Ressource (DE-627)32040661X (DE-600)2000759-0 (DE-576)259484393 1350-4487 nnns volume:171 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2360 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 33.40 Kernphysik VZ 42.14 Strahlenbiologie VZ 44.64 Radiologie VZ AR 171
allfields_unstemmed	10.1016/j.radmeas.2024.107063 doi (DE-627)ELV066972043 (ELSEVIER)S1350-4487(24)00011-8 DE-627 ger DE-627 rda eng 530 VZ 33.40 bkl 42.14 bkl 44.64 bkl Scott, Hayden verfasserin (orcid)0000-0003-1066-1999 aut Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy 2024 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs. OSLD Quality assurance Dose limit Alvarez, Paola verfasserin aut Howell, Rebecca verfasserin aut Riegel, Adam verfasserin aut Sun, Ryan verfasserin aut Kry, Stephen verfasserin aut Enthalten in Radiation measurements Amsterdam [u.a.] : Elsevier Science, 1994 171 Online-Ressource (DE-627)32040661X (DE-600)2000759-0 (DE-576)259484393 1350-4487 nnns volume:171 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2360 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 33.40 Kernphysik VZ 42.14 Strahlenbiologie VZ 44.64 Radiologie VZ AR 171
allfieldsGer	10.1016/j.radmeas.2024.107063 doi (DE-627)ELV066972043 (ELSEVIER)S1350-4487(24)00011-8 DE-627 ger DE-627 rda eng 530 VZ 33.40 bkl 42.14 bkl 44.64 bkl Scott, Hayden verfasserin (orcid)0000-0003-1066-1999 aut Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy 2024 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs. OSLD Quality assurance Dose limit Alvarez, Paola verfasserin aut Howell, Rebecca verfasserin aut Riegel, Adam verfasserin aut Sun, Ryan verfasserin aut Kry, Stephen verfasserin aut Enthalten in Radiation measurements Amsterdam [u.a.] : Elsevier Science, 1994 171 Online-Ressource (DE-627)32040661X (DE-600)2000759-0 (DE-576)259484393 1350-4487 nnns volume:171 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2360 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 33.40 Kernphysik VZ 42.14 Strahlenbiologie VZ 44.64 Radiologie VZ AR 171
allfieldsSound	10.1016/j.radmeas.2024.107063 doi (DE-627)ELV066972043 (ELSEVIER)S1350-4487(24)00011-8 DE-627 ger DE-627 rda eng 530 VZ 33.40 bkl 42.14 bkl 44.64 bkl Scott, Hayden verfasserin (orcid)0000-0003-1066-1999 aut Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy 2024 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs. OSLD Quality assurance Dose limit Alvarez, Paola verfasserin aut Howell, Rebecca verfasserin aut Riegel, Adam verfasserin aut Sun, Ryan verfasserin aut Kry, Stephen verfasserin aut Enthalten in Radiation measurements Amsterdam [u.a.] : Elsevier Science, 1994 171 Online-Ressource (DE-627)32040661X (DE-600)2000759-0 (DE-576)259484393 1350-4487 nnns volume:171 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2360 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 33.40 Kernphysik VZ 42.14 Strahlenbiologie VZ 44.64 Radiologie VZ AR 171
language	English
source	Enthalten in Radiation measurements 171 volume:171
sourceStr	Enthalten in Radiation measurements 171 volume:171
format_phy_str_mv	Article
bklname	Kernphysik Strahlenbiologie Radiologie
institution	findex.gbv.de
topic_facet	OSLD Quality assurance Dose limit
dewey-raw	530
isfreeaccess_bool	false
container_title	Radiation measurements
authorswithroles_txt_mv	Scott, Hayden @@aut@@ Alvarez, Paola @@aut@@ Howell, Rebecca @@aut@@ Riegel, Adam @@aut@@ Sun, Ryan @@aut@@ Kry, Stephen @@aut@@
publishDateDaySort_date	2024-01-01T00:00:00Z
hierarchy_top_id	32040661X
dewey-sort	3530
id	ELV066972043
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">ELV066972043</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240210093118.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240210s2024 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.radmeas.2024.107063</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV066972043</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1350-4487(24)00011-8</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">33.40</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">42.14</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.64</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Scott, Hayden</subfield><subfield code="e">verfasserin</subfield><subfield code="0">(orcid)0000-0003-1066-1999</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. 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author	Scott, Hayden
spellingShingle	Scott, Hayden ddc 530 bkl 33.40 bkl 42.14 bkl 44.64 misc OSLD misc Quality assurance misc Dose limit Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy
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topic_title	530 VZ 33.40 bkl 42.14 bkl 44.64 bkl Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy OSLD Quality assurance Dose limit
topic	ddc 530 bkl 33.40 bkl 42.14 bkl 44.64 misc OSLD misc Quality assurance misc Dose limit
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title	Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy
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title_full	Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy
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author_browse	Scott, Hayden Alvarez, Paola Howell, Rebecca Riegel, Adam Sun, Ryan Kry, Stephen
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title_sort	lifetime extension of optically stimulated luminescent dosimeters above 10 gy
title_auth	Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy
abstract	Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs.
abstractGer	Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs.
abstract_unstemmed	Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs.
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title_short	Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy
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author2	Alvarez, Paola Howell, Rebecca Riegel, Adam Sun, Ryan Kry, Stephen
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doi_str	10.1016/j.radmeas.2024.107063
up_date	2024-07-06T19:38:27.695Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">ELV066972043</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240210093118.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240210s2024 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.radmeas.2024.107063</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV066972043</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1350-4487(24)00011-8</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">33.40</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">42.14</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.64</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Scott, Hayden</subfield><subfield code="e">verfasserin</subfield><subfield code="0">(orcid)0000-0003-1066-1999</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: Optically stimulated luminescent dosimeters (OSLDs) are used in clinical radiation dosimetry, but their sensitivity changes with the accumulated dose, limiting their reusability. Different studies have reported inconsistent results regarding the changes in sensitivity at different accumulated doses, and the reasons for this inconsistency remain unclear. In addition, the extent to which the OSLD linearity and element sensitivity correction factor ( k s , i ) change with the accumulated dose has not been well established.Purpose: We sought to characterize how the individual k s , i and dose non-linearity correction factor ( k L ) change with accumulated dose and how such changes affect the measurement of the dose to water ( D w ) . Determining the extent to which these parameters change with the accumulated dose can help clinics, institutions, and the Imaging and Radiation Oncology Core (IROC) at MD Anderson extend the OSLD accumulated dose limit above 10 Gy and thus increase the efficiency of use of these detectors, including for the remote audit output audits run by IROC for the National Clinical Trials Network.Methods: 95 nanoDot OSLDs were individually irradiated in 4-Gy cycles with 90 cGy used to determine sensitivity, irradiated between 0.25- to 3-Gy to determine linearity, and then irradiated to return all dosimeters to the same total dose history. Repeated measurements between 10 and 23 Gy were performed with the same batch (N = 129) and with a different batch (batch 2, N = 130). Dosimeters were read with a microSTARii system 5–8 h following each irradiation, and each OSLD was bleached for 24 h in the IROC bleaching box prior to every irradiation. A combination of single-factor ANOVA, Levene tests, and linear regressions was used to quantify changes in OSLD characteristics as a function of accumulated dose. The D w was calculated using Equation (1)in the American Association of Physicists in Medicine Task Group 191 report.Results: The signal response of the OSLDs showed stability within 1% up to an accumulated dose of 23 Gy before decreasing with dose. The k s , i remained the same, while linearity changed with accumulated dose but did so in a linear and predictable manner.Conclusion: Our findings improve our understanding of accumulated dose and could help improve overall process efficiency by extending the reusability of OSLDs.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">OSLD</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Quality assurance</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Dose limit</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Alvarez, Paola</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Howell, Rebecca</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Riegel, 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Lifetime extension of optically stimulated luminescent dosimeters above 10 Gy

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