Sperm abnormalities in the PL/J mouse strain: A description and proposed mechanism for malformation
A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibi...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
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| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
1981 |
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| Umfang: |
7 Ill. ; 2 Tab. 13 |
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| Reproduktion: |
Wiley InterScience Backfile Collection 1832-2000 |
|---|---|
| Übergeordnetes Werk: |
in: Gamete Research - New York, NY : Wiley, 4(1981) vom: März, Seite 171-183 |
| Übergeordnetes Werk: |
volume:4 ; year:1981 ; month:03 ; pages:171-183 ; extent:13 |
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NLEJ160895103 |
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| 520 | |a A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibit relatively normal motility. Electron microscopy of the testes indicates that some of the abnormal sperm in PL/J males result from a failure of the paired centrioles to attain a normal position on the nucleus opposite the acrosome prior to implantation, or to attach at all. The centrioles that are not attached to the nuclear envelope can differentiate to form the principal piece and midpiece region. The frequency of headless variants in heterozygous F1 indicates that the trait is mainly recessive. The offspring from the backcross of the F1 to homozygous PL/J parents did not give a clear-cut segregation pattern. The frequency of abnormal sperm in the F1 and the backcross is higher when the female parent is a PL/J. | ||
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(DE-627)NLEJ160895103 DE-627 ger DE-627 rakwb eng Sperm abnormalities in the PL/J mouse strain: A description and proposed mechanism for malformation 1981 7 Ill. 2 Tab. 13 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibit relatively normal motility. Electron microscopy of the testes indicates that some of the abnormal sperm in PL/J males result from a failure of the paired centrioles to attain a normal position on the nucleus opposite the acrosome prior to implantation, or to attach at all. The centrioles that are not attached to the nuclear envelope can differentiate to form the principal piece and midpiece region. The frequency of headless variants in heterozygous F1 indicates that the trait is mainly recessive. The offspring from the backcross of the F1 to homozygous PL/J parents did not give a clear-cut segregation pattern. The frequency of abnormal sperm in the F1 and the backcross is higher when the female parent is a PL/J. Wiley InterScience Backfile Collection 1832-2000 Burkhart, J. G. oth Malling, H. V. oth in Gamete Research New York, NY : Wiley 4(1981) vom: März, Seite 171-183 (DE-627)NLEJ159071038 0148-7280 nnns volume:4 year:1981 month:03 pages:171-183 extent:13 http://dx.doi.org/10.1002/mrd.1120040302 text/html Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-WIS GBV_NL_ARTICLE AR 4 1981 3 171-183 13 |
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(DE-627)NLEJ160895103 DE-627 ger DE-627 rakwb eng Sperm abnormalities in the PL/J mouse strain: A description and proposed mechanism for malformation 1981 7 Ill. 2 Tab. 13 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibit relatively normal motility. Electron microscopy of the testes indicates that some of the abnormal sperm in PL/J males result from a failure of the paired centrioles to attain a normal position on the nucleus opposite the acrosome prior to implantation, or to attach at all. The centrioles that are not attached to the nuclear envelope can differentiate to form the principal piece and midpiece region. The frequency of headless variants in heterozygous F1 indicates that the trait is mainly recessive. The offspring from the backcross of the F1 to homozygous PL/J parents did not give a clear-cut segregation pattern. The frequency of abnormal sperm in the F1 and the backcross is higher when the female parent is a PL/J. Wiley InterScience Backfile Collection 1832-2000 Burkhart, J. G. oth Malling, H. V. oth in Gamete Research New York, NY : Wiley 4(1981) vom: März, Seite 171-183 (DE-627)NLEJ159071038 0148-7280 nnns volume:4 year:1981 month:03 pages:171-183 extent:13 http://dx.doi.org/10.1002/mrd.1120040302 text/html Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-WIS GBV_NL_ARTICLE AR 4 1981 3 171-183 13 |
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(DE-627)NLEJ160895103 DE-627 ger DE-627 rakwb eng Sperm abnormalities in the PL/J mouse strain: A description and proposed mechanism for malformation 1981 7 Ill. 2 Tab. 13 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibit relatively normal motility. Electron microscopy of the testes indicates that some of the abnormal sperm in PL/J males result from a failure of the paired centrioles to attain a normal position on the nucleus opposite the acrosome prior to implantation, or to attach at all. The centrioles that are not attached to the nuclear envelope can differentiate to form the principal piece and midpiece region. The frequency of headless variants in heterozygous F1 indicates that the trait is mainly recessive. The offspring from the backcross of the F1 to homozygous PL/J parents did not give a clear-cut segregation pattern. The frequency of abnormal sperm in the F1 and the backcross is higher when the female parent is a PL/J. Wiley InterScience Backfile Collection 1832-2000 Burkhart, J. G. oth Malling, H. V. oth in Gamete Research New York, NY : Wiley 4(1981) vom: März, Seite 171-183 (DE-627)NLEJ159071038 0148-7280 nnns volume:4 year:1981 month:03 pages:171-183 extent:13 http://dx.doi.org/10.1002/mrd.1120040302 text/html Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-WIS GBV_NL_ARTICLE AR 4 1981 3 171-183 13 |
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(DE-627)NLEJ160895103 DE-627 ger DE-627 rakwb eng Sperm abnormalities in the PL/J mouse strain: A description and proposed mechanism for malformation 1981 7 Ill. 2 Tab. 13 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibit relatively normal motility. Electron microscopy of the testes indicates that some of the abnormal sperm in PL/J males result from a failure of the paired centrioles to attain a normal position on the nucleus opposite the acrosome prior to implantation, or to attach at all. The centrioles that are not attached to the nuclear envelope can differentiate to form the principal piece and midpiece region. The frequency of headless variants in heterozygous F1 indicates that the trait is mainly recessive. The offspring from the backcross of the F1 to homozygous PL/J parents did not give a clear-cut segregation pattern. The frequency of abnormal sperm in the F1 and the backcross is higher when the female parent is a PL/J. Wiley InterScience Backfile Collection 1832-2000 Burkhart, J. G. oth Malling, H. V. oth in Gamete Research New York, NY : Wiley 4(1981) vom: März, Seite 171-183 (DE-627)NLEJ159071038 0148-7280 nnns volume:4 year:1981 month:03 pages:171-183 extent:13 http://dx.doi.org/10.1002/mrd.1120040302 text/html Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-WIS GBV_NL_ARTICLE AR 4 1981 3 171-183 13 |
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(DE-627)NLEJ160895103 DE-627 ger DE-627 rakwb eng Sperm abnormalities in the PL/J mouse strain: A description and proposed mechanism for malformation 1981 7 Ill. 2 Tab. 13 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibit relatively normal motility. Electron microscopy of the testes indicates that some of the abnormal sperm in PL/J males result from a failure of the paired centrioles to attain a normal position on the nucleus opposite the acrosome prior to implantation, or to attach at all. The centrioles that are not attached to the nuclear envelope can differentiate to form the principal piece and midpiece region. The frequency of headless variants in heterozygous F1 indicates that the trait is mainly recessive. The offspring from the backcross of the F1 to homozygous PL/J parents did not give a clear-cut segregation pattern. The frequency of abnormal sperm in the F1 and the backcross is higher when the female parent is a PL/J. Wiley InterScience Backfile Collection 1832-2000 Burkhart, J. G. oth Malling, H. V. oth in Gamete Research New York, NY : Wiley 4(1981) vom: März, Seite 171-183 (DE-627)NLEJ159071038 0148-7280 nnns volume:4 year:1981 month:03 pages:171-183 extent:13 http://dx.doi.org/10.1002/mrd.1120040302 text/html Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-WIS GBV_NL_ARTICLE AR 4 1981 3 171-183 13 |
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sperm abnormalities in the pl/j mouse strain: a description and proposed mechanism for malformation |
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Sperm abnormalities in the PL/J mouse strain: A description and proposed mechanism for malformation |
| abstract |
A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibit relatively normal motility. Electron microscopy of the testes indicates that some of the abnormal sperm in PL/J males result from a failure of the paired centrioles to attain a normal position on the nucleus opposite the acrosome prior to implantation, or to attach at all. The centrioles that are not attached to the nuclear envelope can differentiate to form the principal piece and midpiece region. The frequency of headless variants in heterozygous F1 indicates that the trait is mainly recessive. The offspring from the backcross of the F1 to homozygous PL/J parents did not give a clear-cut segregation pattern. The frequency of abnormal sperm in the F1 and the backcross is higher when the female parent is a PL/J. |
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A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibit relatively normal motility. Electron microscopy of the testes indicates that some of the abnormal sperm in PL/J males result from a failure of the paired centrioles to attain a normal position on the nucleus opposite the acrosome prior to implantation, or to attach at all. The centrioles that are not attached to the nuclear envelope can differentiate to form the principal piece and midpiece region. The frequency of headless variants in heterozygous F1 indicates that the trait is mainly recessive. The offspring from the backcross of the F1 to homozygous PL/J parents did not give a clear-cut segregation pattern. The frequency of abnormal sperm in the F1 and the backcross is higher when the female parent is a PL/J. |
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A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibit relatively normal motility. Electron microscopy of the testes indicates that some of the abnormal sperm in PL/J males result from a failure of the paired centrioles to attain a normal position on the nucleus opposite the acrosome prior to implantation, or to attach at all. The centrioles that are not attached to the nuclear envelope can differentiate to form the principal piece and midpiece region. The frequency of headless variants in heterozygous F1 indicates that the trait is mainly recessive. The offspring from the backcross of the F1 to homozygous PL/J parents did not give a clear-cut segregation pattern. The frequency of abnormal sperm in the F1 and the backcross is higher when the female parent is a PL/J. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ160895103</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707051106.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070201s1981 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ160895103</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Sperm abnormalities in the PL/J mouse strain: A description and proposed mechanism for malformation</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1981</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="b">7 Ill.</subfield><subfield code="b">2 Tab.</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">13</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">A high frequency (42%) of sperm from the inbred homozygous mouse strain PL/J are abnormal. Head shape abnormalities occur in 15% of the total sperm; and 27% of the sperm are headless, with the mitochondria condensed into a mass at the caudal end of the midpiece region. The sperm without heads exhibit relatively normal motility. Electron microscopy of the testes indicates that some of the abnormal sperm in PL/J males result from a failure of the paired centrioles to attain a normal position on the nucleus opposite the acrosome prior to implantation, or to attach at all. The centrioles that are not attached to the nuclear envelope can differentiate to form the principal piece and midpiece region. The frequency of headless variants in heterozygous F1 indicates that the trait is mainly recessive. The offspring from the backcross of the F1 to homozygous PL/J parents did not give a clear-cut segregation pattern. The frequency of abnormal sperm in the F1 and the backcross is higher when the female parent is a PL/J.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Wiley InterScience Backfile Collection 1832-2000</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Burkhart, J. G.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Malling, H. V.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Gamete Research</subfield><subfield code="d">New York, NY : Wiley</subfield><subfield code="g">4(1981) vom: März, Seite 171-183</subfield><subfield code="w">(DE-627)NLEJ159071038</subfield><subfield code="x">0148-7280</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:4</subfield><subfield code="g">year:1981</subfield><subfield code="g">month:03</subfield><subfield code="g">pages:171-183</subfield><subfield code="g">extent:13</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1002/mrd.1120040302</subfield><subfield code="q">text/html</subfield><subfield code="z">Deutschlandweit zugänglich</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-WIS</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">4</subfield><subfield code="j">1981</subfield><subfield code="c">3</subfield><subfield code="h">171-183</subfield><subfield code="g">13</subfield></datafield></record></collection>
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7.4012785 |