Serum FSH, LH and testosterone in the male rhesus following prostaglandin injection
Adult male rhesus were treated with PGE"2, PGF"2"α or the 13,14-dihydro-15-keto metabolite of PGE"2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No signific...
Ausführliche Beschreibung
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| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1979 |
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| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
|---|---|
| Übergeordnetes Werk: |
in: Prostaglandins - Amsterdam : Elsevier, 18(1979), 1, Seite 117-126 |
| Übergeordnetes Werk: |
volume:18 ; year:1979 ; number:1 ; pages:117-126 |
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| 245 | 1 | 0 | |a Serum FSH, LH and testosterone in the male rhesus following prostaglandin injection |
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| 520 | |a Adult male rhesus were treated with PGE"2, PGF"2"α or the 13,14-dihydro-15-keto metabolite of PGE"2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No significant changes were noted in controls or following the metabolite injection. FSH increased gradually for 4 hours after metabolite treatment. In contrast, injection of PGF"2"α was followed by an abrupt (within 15 minutes) increase in LH and testosterone. FSH increased gradually in 2 of 3 treated animals. Injection of PGE"2 was followed by a similar abrupt increase in LH concentration. This was not always associated with a significant increase in testosterone or FSH. These results demonstrate that injections of PGE"2 or PGF"2"α can change serum gonadotropin and testosterone concentrations in male rhesus monkeys, and that the effects of these two prostaglandins are qualitatively different. | ||
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(DE-627)NLEJ177049529 (DE-599)GBVNLZ177049529 DE-627 ger DE-627 rakwb eng Serum FSH, LH and testosterone in the male rhesus following prostaglandin injection 1979 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Adult male rhesus were treated with PGE"2, PGF"2"α or the 13,14-dihydro-15-keto metabolite of PGE"2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No significant changes were noted in controls or following the metabolite injection. FSH increased gradually for 4 hours after metabolite treatment. In contrast, injection of PGF"2"α was followed by an abrupt (within 15 minutes) increase in LH and testosterone. FSH increased gradually in 2 of 3 treated animals. Injection of PGE"2 was followed by a similar abrupt increase in LH concentration. This was not always associated with a significant increase in testosterone or FSH. These results demonstrate that injections of PGE"2 or PGF"2"α can change serum gonadotropin and testosterone concentrations in male rhesus monkeys, and that the effects of these two prostaglandins are qualitatively different. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Kimball, F.A. oth Kirton, K.T. oth Forbes, A.D. oth Frielink, R.D. oth Porteus, S.E. oth Wilks, J.W. oth Mohberg, N.R. oth Turner, L.F. oth in Prostaglandins Amsterdam : Elsevier 18(1979), 1, Seite 117-126 (DE-627)NLEJ17693233X (DE-600)2140297-8 0090-6980 nnns volume:18 year:1979 number:1 pages:117-126 http://dx.doi.org/10.1016/S0090-6980(79)80029-5 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 18 1979 1 117-126 |
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(DE-627)NLEJ177049529 (DE-599)GBVNLZ177049529 DE-627 ger DE-627 rakwb eng Serum FSH, LH and testosterone in the male rhesus following prostaglandin injection 1979 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Adult male rhesus were treated with PGE"2, PGF"2"α or the 13,14-dihydro-15-keto metabolite of PGE"2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No significant changes were noted in controls or following the metabolite injection. FSH increased gradually for 4 hours after metabolite treatment. In contrast, injection of PGF"2"α was followed by an abrupt (within 15 minutes) increase in LH and testosterone. FSH increased gradually in 2 of 3 treated animals. Injection of PGE"2 was followed by a similar abrupt increase in LH concentration. This was not always associated with a significant increase in testosterone or FSH. These results demonstrate that injections of PGE"2 or PGF"2"α can change serum gonadotropin and testosterone concentrations in male rhesus monkeys, and that the effects of these two prostaglandins are qualitatively different. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Kimball, F.A. oth Kirton, K.T. oth Forbes, A.D. oth Frielink, R.D. oth Porteus, S.E. oth Wilks, J.W. oth Mohberg, N.R. oth Turner, L.F. oth in Prostaglandins Amsterdam : Elsevier 18(1979), 1, Seite 117-126 (DE-627)NLEJ17693233X (DE-600)2140297-8 0090-6980 nnns volume:18 year:1979 number:1 pages:117-126 http://dx.doi.org/10.1016/S0090-6980(79)80029-5 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 18 1979 1 117-126 |
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(DE-627)NLEJ177049529 (DE-599)GBVNLZ177049529 DE-627 ger DE-627 rakwb eng Serum FSH, LH and testosterone in the male rhesus following prostaglandin injection 1979 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Adult male rhesus were treated with PGE"2, PGF"2"α or the 13,14-dihydro-15-keto metabolite of PGE"2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No significant changes were noted in controls or following the metabolite injection. FSH increased gradually for 4 hours after metabolite treatment. In contrast, injection of PGF"2"α was followed by an abrupt (within 15 minutes) increase in LH and testosterone. FSH increased gradually in 2 of 3 treated animals. Injection of PGE"2 was followed by a similar abrupt increase in LH concentration. This was not always associated with a significant increase in testosterone or FSH. These results demonstrate that injections of PGE"2 or PGF"2"α can change serum gonadotropin and testosterone concentrations in male rhesus monkeys, and that the effects of these two prostaglandins are qualitatively different. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Kimball, F.A. oth Kirton, K.T. oth Forbes, A.D. oth Frielink, R.D. oth Porteus, S.E. oth Wilks, J.W. oth Mohberg, N.R. oth Turner, L.F. oth in Prostaglandins Amsterdam : Elsevier 18(1979), 1, Seite 117-126 (DE-627)NLEJ17693233X (DE-600)2140297-8 0090-6980 nnns volume:18 year:1979 number:1 pages:117-126 http://dx.doi.org/10.1016/S0090-6980(79)80029-5 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 18 1979 1 117-126 |
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(DE-627)NLEJ177049529 (DE-599)GBVNLZ177049529 DE-627 ger DE-627 rakwb eng Serum FSH, LH and testosterone in the male rhesus following prostaglandin injection 1979 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Adult male rhesus were treated with PGE"2, PGF"2"α or the 13,14-dihydro-15-keto metabolite of PGE"2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No significant changes were noted in controls or following the metabolite injection. FSH increased gradually for 4 hours after metabolite treatment. In contrast, injection of PGF"2"α was followed by an abrupt (within 15 minutes) increase in LH and testosterone. FSH increased gradually in 2 of 3 treated animals. Injection of PGE"2 was followed by a similar abrupt increase in LH concentration. This was not always associated with a significant increase in testosterone or FSH. These results demonstrate that injections of PGE"2 or PGF"2"α can change serum gonadotropin and testosterone concentrations in male rhesus monkeys, and that the effects of these two prostaglandins are qualitatively different. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Kimball, F.A. oth Kirton, K.T. oth Forbes, A.D. oth Frielink, R.D. oth Porteus, S.E. oth Wilks, J.W. oth Mohberg, N.R. oth Turner, L.F. oth in Prostaglandins Amsterdam : Elsevier 18(1979), 1, Seite 117-126 (DE-627)NLEJ17693233X (DE-600)2140297-8 0090-6980 nnns volume:18 year:1979 number:1 pages:117-126 http://dx.doi.org/10.1016/S0090-6980(79)80029-5 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 18 1979 1 117-126 |
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(DE-627)NLEJ177049529 (DE-599)GBVNLZ177049529 DE-627 ger DE-627 rakwb eng Serum FSH, LH and testosterone in the male rhesus following prostaglandin injection 1979 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Adult male rhesus were treated with PGE"2, PGF"2"α or the 13,14-dihydro-15-keto metabolite of PGE"2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No significant changes were noted in controls or following the metabolite injection. FSH increased gradually for 4 hours after metabolite treatment. In contrast, injection of PGF"2"α was followed by an abrupt (within 15 minutes) increase in LH and testosterone. FSH increased gradually in 2 of 3 treated animals. Injection of PGE"2 was followed by a similar abrupt increase in LH concentration. This was not always associated with a significant increase in testosterone or FSH. These results demonstrate that injections of PGE"2 or PGF"2"α can change serum gonadotropin and testosterone concentrations in male rhesus monkeys, and that the effects of these two prostaglandins are qualitatively different. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Kimball, F.A. oth Kirton, K.T. oth Forbes, A.D. oth Frielink, R.D. oth Porteus, S.E. oth Wilks, J.W. oth Mohberg, N.R. oth Turner, L.F. oth in Prostaglandins Amsterdam : Elsevier 18(1979), 1, Seite 117-126 (DE-627)NLEJ17693233X (DE-600)2140297-8 0090-6980 nnns volume:18 year:1979 number:1 pages:117-126 http://dx.doi.org/10.1016/S0090-6980(79)80029-5 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 18 1979 1 117-126 |
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serum fsh, lh and testosterone in the male rhesus following prostaglandin injection |
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Serum FSH, LH and testosterone in the male rhesus following prostaglandin injection |
| abstract |
Adult male rhesus were treated with PGE"2, PGF"2"α or the 13,14-dihydro-15-keto metabolite of PGE"2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No significant changes were noted in controls or following the metabolite injection. FSH increased gradually for 4 hours after metabolite treatment. In contrast, injection of PGF"2"α was followed by an abrupt (within 15 minutes) increase in LH and testosterone. FSH increased gradually in 2 of 3 treated animals. Injection of PGE"2 was followed by a similar abrupt increase in LH concentration. This was not always associated with a significant increase in testosterone or FSH. These results demonstrate that injections of PGE"2 or PGF"2"α can change serum gonadotropin and testosterone concentrations in male rhesus monkeys, and that the effects of these two prostaglandins are qualitatively different. |
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Adult male rhesus were treated with PGE"2, PGF"2"α or the 13,14-dihydro-15-keto metabolite of PGE"2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No significant changes were noted in controls or following the metabolite injection. FSH increased gradually for 4 hours after metabolite treatment. In contrast, injection of PGF"2"α was followed by an abrupt (within 15 minutes) increase in LH and testosterone. FSH increased gradually in 2 of 3 treated animals. Injection of PGE"2 was followed by a similar abrupt increase in LH concentration. This was not always associated with a significant increase in testosterone or FSH. These results demonstrate that injections of PGE"2 or PGF"2"α can change serum gonadotropin and testosterone concentrations in male rhesus monkeys, and that the effects of these two prostaglandins are qualitatively different. |
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Adult male rhesus were treated with PGE"2, PGF"2"α or the 13,14-dihydro-15-keto metabolite of PGE"2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No significant changes were noted in controls or following the metabolite injection. FSH increased gradually for 4 hours after metabolite treatment. In contrast, injection of PGF"2"α was followed by an abrupt (within 15 minutes) increase in LH and testosterone. FSH increased gradually in 2 of 3 treated animals. Injection of PGE"2 was followed by a similar abrupt increase in LH concentration. This was not always associated with a significant increase in testosterone or FSH. These results demonstrate that injections of PGE"2 or PGF"2"α can change serum gonadotropin and testosterone concentrations in male rhesus monkeys, and that the effects of these two prostaglandins are qualitatively different. |
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Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same uninjected animals. No significant changes were noted in controls or following the metabolite injection. FSH increased gradually for 4 hours after metabolite treatment. In contrast, injection of PGF"2"α was followed by an abrupt (within 15 minutes) increase in LH and testosterone. FSH increased gradually in 2 of 3 treated animals. Injection of PGE"2 was followed by a similar abrupt increase in LH concentration. This was not always associated with a significant increase in testosterone or FSH. These results demonstrate that injections of PGE"2 or PGF"2"α can change serum gonadotropin and testosterone concentrations in male rhesus monkeys, and that the effects of these two prostaglandins are qualitatively different.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kimball, F.A.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kirton, K.T.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Forbes, A.D.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Frielink, R.D.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Porteus, S.E.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Wilks, J.W.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mohberg, N.R.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Turner, L.F.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Prostaglandins</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">18(1979), 1, Seite 117-126</subfield><subfield code="w">(DE-627)NLEJ17693233X</subfield><subfield code="w">(DE-600)2140297-8</subfield><subfield code="x">0090-6980</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:18</subfield><subfield code="g">year:1979</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:117-126</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1016/S0090-6980(79)80029-5</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">18</subfield><subfield code="j">1979</subfield><subfield code="e">1</subfield><subfield code="h">117-126</subfield></datafield></record></collection>
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