Melatonin circadian rhythm in anorexia nervosa and obesity
The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern. Blood sam...
Ausführliche Beschreibung
Autor*in: |
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E-Artikel |
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Englisch |
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1988 |
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Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
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Übergeordnetes Werk: |
in: Psychiatry Research - Amsterdam : Elsevier, 23(1988), 3, Seite 267-276 |
Übergeordnetes Werk: |
volume:23 ; year:1988 ; number:3 ; pages:267-276 |
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NLEJ182036820 |
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520 | |a The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern. Blood samples for melatonin were drawn every 4 hours from 0400h to 2400h and every 2 hours from 2400h to 0400h. Mean 24-hour melatonin secretion was significantly higher in AN than in OB patients and controls. Melatonin circadian rhythms were disrupted in 8 of the 12 AN patients and in 9 of the 13 OB subjects, with phase-advanced nocturnal rises, abnormal diurnal peaks, or no nocturnal rises. The population mean cosinor analysis validated the existence of a significant circadian rhythm of the hormone in AN but not in OB subjects. No significant correlation between mean 24-hour secretion or type of circadian alterations and degree of weight deficit or excess was observed. The circadian alterations of melatonin in AN and OB may be linked to impaired secretory tonus of nonadrenalin in the central nervous system, possibly unrelated to feeding patterns. | ||
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(DE-627)NLEJ182036820 (DE-599)GBVNLZ182036820 DE-627 ger DE-627 rakwb eng Melatonin circadian rhythm in anorexia nervosa and obesity 1988 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern. Blood samples for melatonin were drawn every 4 hours from 0400h to 2400h and every 2 hours from 2400h to 0400h. Mean 24-hour melatonin secretion was significantly higher in AN than in OB patients and controls. Melatonin circadian rhythms were disrupted in 8 of the 12 AN patients and in 9 of the 13 OB subjects, with phase-advanced nocturnal rises, abnormal diurnal peaks, or no nocturnal rises. The population mean cosinor analysis validated the existence of a significant circadian rhythm of the hormone in AN but not in OB subjects. No significant correlation between mean 24-hour secretion or type of circadian alterations and degree of weight deficit or excess was observed. The circadian alterations of melatonin in AN and OB may be linked to impaired secretory tonus of nonadrenalin in the central nervous system, possibly unrelated to feeding patterns. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Brambilla, F. oth Fraschini, F. oth Esposti, G. oth Bossolo, P.A. oth Marelli, G. oth Ferrari, E. oth in Psychiatry Research Amsterdam : Elsevier 23(1988), 3, Seite 267-276 (DE-627)NLEJ177074922 (DE-600)1500675-X 0165-1781 nnns volume:23 year:1988 number:3 pages:267-276 http://linkinghub.elsevier.com/retrieve/pii/0165-1781(88)90017-0 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 23 1988 3 267-276 |
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(DE-627)NLEJ182036820 (DE-599)GBVNLZ182036820 DE-627 ger DE-627 rakwb eng Melatonin circadian rhythm in anorexia nervosa and obesity 1988 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern. Blood samples for melatonin were drawn every 4 hours from 0400h to 2400h and every 2 hours from 2400h to 0400h. Mean 24-hour melatonin secretion was significantly higher in AN than in OB patients and controls. Melatonin circadian rhythms were disrupted in 8 of the 12 AN patients and in 9 of the 13 OB subjects, with phase-advanced nocturnal rises, abnormal diurnal peaks, or no nocturnal rises. The population mean cosinor analysis validated the existence of a significant circadian rhythm of the hormone in AN but not in OB subjects. No significant correlation between mean 24-hour secretion or type of circadian alterations and degree of weight deficit or excess was observed. The circadian alterations of melatonin in AN and OB may be linked to impaired secretory tonus of nonadrenalin in the central nervous system, possibly unrelated to feeding patterns. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Brambilla, F. oth Fraschini, F. oth Esposti, G. oth Bossolo, P.A. oth Marelli, G. oth Ferrari, E. oth in Psychiatry Research Amsterdam : Elsevier 23(1988), 3, Seite 267-276 (DE-627)NLEJ177074922 (DE-600)1500675-X 0165-1781 nnns volume:23 year:1988 number:3 pages:267-276 http://linkinghub.elsevier.com/retrieve/pii/0165-1781(88)90017-0 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 23 1988 3 267-276 |
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(DE-627)NLEJ182036820 (DE-599)GBVNLZ182036820 DE-627 ger DE-627 rakwb eng Melatonin circadian rhythm in anorexia nervosa and obesity 1988 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern. Blood samples for melatonin were drawn every 4 hours from 0400h to 2400h and every 2 hours from 2400h to 0400h. Mean 24-hour melatonin secretion was significantly higher in AN than in OB patients and controls. Melatonin circadian rhythms were disrupted in 8 of the 12 AN patients and in 9 of the 13 OB subjects, with phase-advanced nocturnal rises, abnormal diurnal peaks, or no nocturnal rises. The population mean cosinor analysis validated the existence of a significant circadian rhythm of the hormone in AN but not in OB subjects. No significant correlation between mean 24-hour secretion or type of circadian alterations and degree of weight deficit or excess was observed. The circadian alterations of melatonin in AN and OB may be linked to impaired secretory tonus of nonadrenalin in the central nervous system, possibly unrelated to feeding patterns. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Brambilla, F. oth Fraschini, F. oth Esposti, G. oth Bossolo, P.A. oth Marelli, G. oth Ferrari, E. oth in Psychiatry Research Amsterdam : Elsevier 23(1988), 3, Seite 267-276 (DE-627)NLEJ177074922 (DE-600)1500675-X 0165-1781 nnns volume:23 year:1988 number:3 pages:267-276 http://linkinghub.elsevier.com/retrieve/pii/0165-1781(88)90017-0 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 23 1988 3 267-276 |
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(DE-627)NLEJ182036820 (DE-599)GBVNLZ182036820 DE-627 ger DE-627 rakwb eng Melatonin circadian rhythm in anorexia nervosa and obesity 1988 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern. Blood samples for melatonin were drawn every 4 hours from 0400h to 2400h and every 2 hours from 2400h to 0400h. Mean 24-hour melatonin secretion was significantly higher in AN than in OB patients and controls. Melatonin circadian rhythms were disrupted in 8 of the 12 AN patients and in 9 of the 13 OB subjects, with phase-advanced nocturnal rises, abnormal diurnal peaks, or no nocturnal rises. The population mean cosinor analysis validated the existence of a significant circadian rhythm of the hormone in AN but not in OB subjects. No significant correlation between mean 24-hour secretion or type of circadian alterations and degree of weight deficit or excess was observed. The circadian alterations of melatonin in AN and OB may be linked to impaired secretory tonus of nonadrenalin in the central nervous system, possibly unrelated to feeding patterns. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Brambilla, F. oth Fraschini, F. oth Esposti, G. oth Bossolo, P.A. oth Marelli, G. oth Ferrari, E. oth in Psychiatry Research Amsterdam : Elsevier 23(1988), 3, Seite 267-276 (DE-627)NLEJ177074922 (DE-600)1500675-X 0165-1781 nnns volume:23 year:1988 number:3 pages:267-276 http://linkinghub.elsevier.com/retrieve/pii/0165-1781(88)90017-0 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 23 1988 3 267-276 |
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Melatonin circadian rhythm in anorexia nervosa and obesity |
abstract |
The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern. Blood samples for melatonin were drawn every 4 hours from 0400h to 2400h and every 2 hours from 2400h to 0400h. Mean 24-hour melatonin secretion was significantly higher in AN than in OB patients and controls. Melatonin circadian rhythms were disrupted in 8 of the 12 AN patients and in 9 of the 13 OB subjects, with phase-advanced nocturnal rises, abnormal diurnal peaks, or no nocturnal rises. The population mean cosinor analysis validated the existence of a significant circadian rhythm of the hormone in AN but not in OB subjects. No significant correlation between mean 24-hour secretion or type of circadian alterations and degree of weight deficit or excess was observed. The circadian alterations of melatonin in AN and OB may be linked to impaired secretory tonus of nonadrenalin in the central nervous system, possibly unrelated to feeding patterns. |
abstractGer |
The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern. Blood samples for melatonin were drawn every 4 hours from 0400h to 2400h and every 2 hours from 2400h to 0400h. Mean 24-hour melatonin secretion was significantly higher in AN than in OB patients and controls. Melatonin circadian rhythms were disrupted in 8 of the 12 AN patients and in 9 of the 13 OB subjects, with phase-advanced nocturnal rises, abnormal diurnal peaks, or no nocturnal rises. The population mean cosinor analysis validated the existence of a significant circadian rhythm of the hormone in AN but not in OB subjects. No significant correlation between mean 24-hour secretion or type of circadian alterations and degree of weight deficit or excess was observed. The circadian alterations of melatonin in AN and OB may be linked to impaired secretory tonus of nonadrenalin in the central nervous system, possibly unrelated to feeding patterns. |
abstract_unstemmed |
The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern. Blood samples for melatonin were drawn every 4 hours from 0400h to 2400h and every 2 hours from 2400h to 0400h. Mean 24-hour melatonin secretion was significantly higher in AN than in OB patients and controls. Melatonin circadian rhythms were disrupted in 8 of the 12 AN patients and in 9 of the 13 OB subjects, with phase-advanced nocturnal rises, abnormal diurnal peaks, or no nocturnal rises. The population mean cosinor analysis validated the existence of a significant circadian rhythm of the hormone in AN but not in OB subjects. No significant correlation between mean 24-hour secretion or type of circadian alterations and degree of weight deficit or excess was observed. The circadian alterations of melatonin in AN and OB may be linked to impaired secretory tonus of nonadrenalin in the central nervous system, possibly unrelated to feeding patterns. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ182036820</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210706170057.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070505s1988 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ182036820</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ182036820</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Melatonin circadian rhythm in anorexia nervosa and obesity</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1988</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern. Blood samples for melatonin were drawn every 4 hours from 0400h to 2400h and every 2 hours from 2400h to 0400h. Mean 24-hour melatonin secretion was significantly higher in AN than in OB patients and controls. Melatonin circadian rhythms were disrupted in 8 of the 12 AN patients and in 9 of the 13 OB subjects, with phase-advanced nocturnal rises, abnormal diurnal peaks, or no nocturnal rises. The population mean cosinor analysis validated the existence of a significant circadian rhythm of the hormone in AN but not in OB subjects. No significant correlation between mean 24-hour secretion or type of circadian alterations and degree of weight deficit or excess was observed. The circadian alterations of melatonin in AN and OB may be linked to impaired secretory tonus of nonadrenalin in the central nervous system, possibly unrelated to feeding patterns.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brambilla, F.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Fraschini, F.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Esposti, G.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bossolo, P.A.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Marelli, G.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ferrari, E.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Psychiatry Research</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">23(1988), 3, Seite 267-276</subfield><subfield code="w">(DE-627)NLEJ177074922</subfield><subfield code="w">(DE-600)1500675-X</subfield><subfield code="x">0165-1781</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:23</subfield><subfield code="g">year:1988</subfield><subfield code="g">number:3</subfield><subfield code="g">pages:267-276</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://linkinghub.elsevier.com/retrieve/pii/0165-1781(88)90017-0</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">23</subfield><subfield code="j">1988</subfield><subfield code="e">3</subfield><subfield code="h">267-276</subfield></datafield></record></collection>
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