Prenylated Proteins in Regenerating Rat Liver
During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesyl...
Ausführliche Beschreibung
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E-Artikel |
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Englisch |
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1994 |
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Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
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Übergeordnetes Werk: |
in: Biochemical and Biophysical Research Communications - Amsterdam : Elsevier, 200(1994), 3, Seite 1713-1720 |
Übergeordnetes Werk: |
volume:200 ; year:1994 ; number:3 ; pages:1713-1720 |
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NLEJ18346849X |
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520 | |a During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylgeranylated proteins in pre-S phase is confirmed by an increased level of lamin A,B,C and of several GTP-binding proteins. These results suggest a relevance of both farnesylation and geranylgeranylation in this phase of the cell cycle. | ||
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700 | 1 | |a Trentalance, A. |4 oth | |
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(DE-627)NLEJ18346849X (DE-599)GBVNLZ18346849X DE-627 ger DE-627 rakwb eng Prenylated Proteins in Regenerating Rat Liver 1994 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylgeranylated proteins in pre-S phase is confirmed by an increased level of lamin A,B,C and of several GTP-binding proteins. These results suggest a relevance of both farnesylation and geranylgeranylation in this phase of the cell cycle. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Bruscalupi, G. oth Castellano, F. oth Sacco, S. oth Trentalance, A. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 200(1994), 3, Seite 1713-1720 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:200 year:1994 number:3 pages:1713-1720 http://dx.doi.org/10.1006/bbrc.1994.1650 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 200 1994 3 1713-1720 |
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(DE-627)NLEJ18346849X (DE-599)GBVNLZ18346849X DE-627 ger DE-627 rakwb eng Prenylated Proteins in Regenerating Rat Liver 1994 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylgeranylated proteins in pre-S phase is confirmed by an increased level of lamin A,B,C and of several GTP-binding proteins. These results suggest a relevance of both farnesylation and geranylgeranylation in this phase of the cell cycle. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Bruscalupi, G. oth Castellano, F. oth Sacco, S. oth Trentalance, A. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 200(1994), 3, Seite 1713-1720 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:200 year:1994 number:3 pages:1713-1720 http://dx.doi.org/10.1006/bbrc.1994.1650 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 200 1994 3 1713-1720 |
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(DE-627)NLEJ18346849X (DE-599)GBVNLZ18346849X DE-627 ger DE-627 rakwb eng Prenylated Proteins in Regenerating Rat Liver 1994 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylgeranylated proteins in pre-S phase is confirmed by an increased level of lamin A,B,C and of several GTP-binding proteins. These results suggest a relevance of both farnesylation and geranylgeranylation in this phase of the cell cycle. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Bruscalupi, G. oth Castellano, F. oth Sacco, S. oth Trentalance, A. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 200(1994), 3, Seite 1713-1720 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:200 year:1994 number:3 pages:1713-1720 http://dx.doi.org/10.1006/bbrc.1994.1650 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 200 1994 3 1713-1720 |
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(DE-627)NLEJ18346849X (DE-599)GBVNLZ18346849X DE-627 ger DE-627 rakwb eng Prenylated Proteins in Regenerating Rat Liver 1994 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylgeranylated proteins in pre-S phase is confirmed by an increased level of lamin A,B,C and of several GTP-binding proteins. These results suggest a relevance of both farnesylation and geranylgeranylation in this phase of the cell cycle. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Bruscalupi, G. oth Castellano, F. oth Sacco, S. oth Trentalance, A. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 200(1994), 3, Seite 1713-1720 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:200 year:1994 number:3 pages:1713-1720 http://dx.doi.org/10.1006/bbrc.1994.1650 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 200 1994 3 1713-1720 |
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(DE-627)NLEJ18346849X (DE-599)GBVNLZ18346849X DE-627 ger DE-627 rakwb eng Prenylated Proteins in Regenerating Rat Liver 1994 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylgeranylated proteins in pre-S phase is confirmed by an increased level of lamin A,B,C and of several GTP-binding proteins. These results suggest a relevance of both farnesylation and geranylgeranylation in this phase of the cell cycle. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Bruscalupi, G. oth Castellano, F. oth Sacco, S. oth Trentalance, A. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 200(1994), 3, Seite 1713-1720 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:200 year:1994 number:3 pages:1713-1720 http://dx.doi.org/10.1006/bbrc.1994.1650 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 200 1994 3 1713-1720 |
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abstract |
During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylgeranylated proteins in pre-S phase is confirmed by an increased level of lamin A,B,C and of several GTP-binding proteins. These results suggest a relevance of both farnesylation and geranylgeranylation in this phase of the cell cycle. |
abstractGer |
During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylgeranylated proteins in pre-S phase is confirmed by an increased level of lamin A,B,C and of several GTP-binding proteins. These results suggest a relevance of both farnesylation and geranylgeranylation in this phase of the cell cycle. |
abstract_unstemmed |
During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylgeranylated proteins in pre-S phase is confirmed by an increased level of lamin A,B,C and of several GTP-binding proteins. These results suggest a relevance of both farnesylation and geranylgeranylation in this phase of the cell cycle. |
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