Inhibition of morphogenetic cell interactions by 6-diazo-5-oxo-norleucine (DON)
The glutamine analogue 6-diazo-5-oxo-norleucine (DON), known to interfere with the synthesis of glycosaminoglycans and glycoproteins, inhibited kidney tubule induction, while the subsequent stages of metabolic activation and oven morphogenesis were unaffected with the same concentrations. Moreover,...
Ausführliche Beschreibung
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| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1979 |
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| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
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| Übergeordnetes Werk: |
in: Experimental Cell Research - Amsterdam : Elsevier, 121(1979), 1, Seite 121-126 |
| Übergeordnetes Werk: |
volume:121 ; year:1979 ; number:1 ; pages:121-126 |
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NLEJ183673794 |
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| 520 | |a The glutamine analogue 6-diazo-5-oxo-norleucine (DON), known to interfere with the synthesis of glycosaminoglycans and glycoproteins, inhibited kidney tubule induction, while the subsequent stages of metabolic activation and oven morphogenesis were unaffected with the same concentrations. Moreover, close cell contacts, previously shown to be of importance in kidney tubule induction, were retained. Thus, carbohydrates, most likely located at the inductor-target interface, seem to be involved in this form of intercellular communication. | ||
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| 700 | 1 | |a Nordling, S. |4 oth | |
| 700 | 1 | |a Saxen, L. |4 oth | |
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(DE-627)NLEJ183673794 (DE-599)GBVNLZ183673794 DE-627 ger DE-627 rakwb eng Inhibition of morphogenetic cell interactions by 6-diazo-5-oxo-norleucine (DON) 1979 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The glutamine analogue 6-diazo-5-oxo-norleucine (DON), known to interfere with the synthesis of glycosaminoglycans and glycoproteins, inhibited kidney tubule induction, while the subsequent stages of metabolic activation and oven morphogenesis were unaffected with the same concentrations. Moreover, close cell contacts, previously shown to be of importance in kidney tubule induction, were retained. Thus, carbohydrates, most likely located at the inductor-target interface, seem to be involved in this form of intercellular communication. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Ekblom, P. oth Lash, J.W. oth Lehtonen, E. oth Nordling, S. oth Saxen, L. oth in Experimental Cell Research Amsterdam : Elsevier 121(1979), 1, Seite 121-126 (DE-627)NLEJ177031808 (DE-600)1466780-0 0014-4827 nnns volume:121 year:1979 number:1 pages:121-126 http://dx.doi.org/10.1016/0014-4827(79)90451-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 121 1979 1 121-126 |
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(DE-627)NLEJ183673794 (DE-599)GBVNLZ183673794 DE-627 ger DE-627 rakwb eng Inhibition of morphogenetic cell interactions by 6-diazo-5-oxo-norleucine (DON) 1979 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The glutamine analogue 6-diazo-5-oxo-norleucine (DON), known to interfere with the synthesis of glycosaminoglycans and glycoproteins, inhibited kidney tubule induction, while the subsequent stages of metabolic activation and oven morphogenesis were unaffected with the same concentrations. Moreover, close cell contacts, previously shown to be of importance in kidney tubule induction, were retained. Thus, carbohydrates, most likely located at the inductor-target interface, seem to be involved in this form of intercellular communication. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Ekblom, P. oth Lash, J.W. oth Lehtonen, E. oth Nordling, S. oth Saxen, L. oth in Experimental Cell Research Amsterdam : Elsevier 121(1979), 1, Seite 121-126 (DE-627)NLEJ177031808 (DE-600)1466780-0 0014-4827 nnns volume:121 year:1979 number:1 pages:121-126 http://dx.doi.org/10.1016/0014-4827(79)90451-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 121 1979 1 121-126 |
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(DE-627)NLEJ183673794 (DE-599)GBVNLZ183673794 DE-627 ger DE-627 rakwb eng Inhibition of morphogenetic cell interactions by 6-diazo-5-oxo-norleucine (DON) 1979 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The glutamine analogue 6-diazo-5-oxo-norleucine (DON), known to interfere with the synthesis of glycosaminoglycans and glycoproteins, inhibited kidney tubule induction, while the subsequent stages of metabolic activation and oven morphogenesis were unaffected with the same concentrations. Moreover, close cell contacts, previously shown to be of importance in kidney tubule induction, were retained. Thus, carbohydrates, most likely located at the inductor-target interface, seem to be involved in this form of intercellular communication. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Ekblom, P. oth Lash, J.W. oth Lehtonen, E. oth Nordling, S. oth Saxen, L. oth in Experimental Cell Research Amsterdam : Elsevier 121(1979), 1, Seite 121-126 (DE-627)NLEJ177031808 (DE-600)1466780-0 0014-4827 nnns volume:121 year:1979 number:1 pages:121-126 http://dx.doi.org/10.1016/0014-4827(79)90451-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 121 1979 1 121-126 |
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(DE-627)NLEJ183673794 (DE-599)GBVNLZ183673794 DE-627 ger DE-627 rakwb eng Inhibition of morphogenetic cell interactions by 6-diazo-5-oxo-norleucine (DON) 1979 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The glutamine analogue 6-diazo-5-oxo-norleucine (DON), known to interfere with the synthesis of glycosaminoglycans and glycoproteins, inhibited kidney tubule induction, while the subsequent stages of metabolic activation and oven morphogenesis were unaffected with the same concentrations. Moreover, close cell contacts, previously shown to be of importance in kidney tubule induction, were retained. Thus, carbohydrates, most likely located at the inductor-target interface, seem to be involved in this form of intercellular communication. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Ekblom, P. oth Lash, J.W. oth Lehtonen, E. oth Nordling, S. oth Saxen, L. oth in Experimental Cell Research Amsterdam : Elsevier 121(1979), 1, Seite 121-126 (DE-627)NLEJ177031808 (DE-600)1466780-0 0014-4827 nnns volume:121 year:1979 number:1 pages:121-126 http://dx.doi.org/10.1016/0014-4827(79)90451-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 121 1979 1 121-126 |
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(DE-627)NLEJ183673794 (DE-599)GBVNLZ183673794 DE-627 ger DE-627 rakwb eng Inhibition of morphogenetic cell interactions by 6-diazo-5-oxo-norleucine (DON) 1979 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The glutamine analogue 6-diazo-5-oxo-norleucine (DON), known to interfere with the synthesis of glycosaminoglycans and glycoproteins, inhibited kidney tubule induction, while the subsequent stages of metabolic activation and oven morphogenesis were unaffected with the same concentrations. Moreover, close cell contacts, previously shown to be of importance in kidney tubule induction, were retained. Thus, carbohydrates, most likely located at the inductor-target interface, seem to be involved in this form of intercellular communication. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Ekblom, P. oth Lash, J.W. oth Lehtonen, E. oth Nordling, S. oth Saxen, L. oth in Experimental Cell Research Amsterdam : Elsevier 121(1979), 1, Seite 121-126 (DE-627)NLEJ177031808 (DE-600)1466780-0 0014-4827 nnns volume:121 year:1979 number:1 pages:121-126 http://dx.doi.org/10.1016/0014-4827(79)90451-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 121 1979 1 121-126 |
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inhibition of morphogenetic cell interactions by 6-diazo-5-oxo-norleucine (don) |
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Inhibition of morphogenetic cell interactions by 6-diazo-5-oxo-norleucine (DON) |
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The glutamine analogue 6-diazo-5-oxo-norleucine (DON), known to interfere with the synthesis of glycosaminoglycans and glycoproteins, inhibited kidney tubule induction, while the subsequent stages of metabolic activation and oven morphogenesis were unaffected with the same concentrations. Moreover, close cell contacts, previously shown to be of importance in kidney tubule induction, were retained. Thus, carbohydrates, most likely located at the inductor-target interface, seem to be involved in this form of intercellular communication. |
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The glutamine analogue 6-diazo-5-oxo-norleucine (DON), known to interfere with the synthesis of glycosaminoglycans and glycoproteins, inhibited kidney tubule induction, while the subsequent stages of metabolic activation and oven morphogenesis were unaffected with the same concentrations. Moreover, close cell contacts, previously shown to be of importance in kidney tubule induction, were retained. Thus, carbohydrates, most likely located at the inductor-target interface, seem to be involved in this form of intercellular communication. |
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The glutamine analogue 6-diazo-5-oxo-norleucine (DON), known to interfere with the synthesis of glycosaminoglycans and glycoproteins, inhibited kidney tubule induction, while the subsequent stages of metabolic activation and oven morphogenesis were unaffected with the same concentrations. Moreover, close cell contacts, previously shown to be of importance in kidney tubule induction, were retained. Thus, carbohydrates, most likely located at the inductor-target interface, seem to be involved in this form of intercellular communication. |
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