In vivo neurotoxic effects of dieldrin on giant nerve fibers and escape reflex function in the earthworm, Eisenia foetida
Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fi...
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E-Artikel |
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Englisch |
| Erschienen: |
1984 |
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| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
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| Übergeordnetes Werk: |
in: Pesticide Biochemistry and Physiology - Amsterdam : Elsevier, 22(1984), 1, Seite 93-103 |
| Übergeordnetes Werk: |
volume:22 ; year:1984 ; number:1 ; pages:93-103 |
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| 245 | 1 | 0 | |a In vivo neurotoxic effects of dieldrin on giant nerve fibers and escape reflex function in the earthworm, Eisenia foetida |
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| 520 | |a Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fiber conduction velocities were seen within a concentration range of 1.4 to 288 ppm. At a high concentration (288 ppm) the decreases in velocity occurred in as little as 90 min, but at low concentrations decreases in velocity occurred much more gradually. Other physiological and behavioral effects of dieldrin treatment included (i) after-discharges of giant fibers following brief mechanical stimulation, (ii) spontaneous bursts of giant fiber spikes, (iii) reductions in the amplitude of giant fiber-mediated muscle potentials, (iv) tonic spasms involving end-to-end shortening and body stiffening, (v) ataxia, and (vi) reduction in body weight. Thus, the in vivo effects of dieldrin in earthworms are characterized by a diverse and complex set of physiological and behavioral symptoms. Possible mechanisms underlying these effects are discussed in relation to the generally accepted mode of dieldrin action on synaptic transmission. | ||
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(DE-627)NLEJ183754883 (DE-599)GBVNLZ183754883 DE-627 ger DE-627 rakwb eng In vivo neurotoxic effects of dieldrin on giant nerve fibers and escape reflex function in the earthworm, Eisenia foetida 1984 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fiber conduction velocities were seen within a concentration range of 1.4 to 288 ppm. At a high concentration (288 ppm) the decreases in velocity occurred in as little as 90 min, but at low concentrations decreases in velocity occurred much more gradually. Other physiological and behavioral effects of dieldrin treatment included (i) after-discharges of giant fibers following brief mechanical stimulation, (ii) spontaneous bursts of giant fiber spikes, (iii) reductions in the amplitude of giant fiber-mediated muscle potentials, (iv) tonic spasms involving end-to-end shortening and body stiffening, (v) ataxia, and (vi) reduction in body weight. Thus, the in vivo effects of dieldrin in earthworms are characterized by a diverse and complex set of physiological and behavioral symptoms. Possible mechanisms underlying these effects are discussed in relation to the generally accepted mode of dieldrin action on synaptic transmission. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Drewes, C.D. oth Vining, E.P. oth in Pesticide Biochemistry and Physiology Amsterdam : Elsevier 22(1984), 1, Seite 93-103 (DE-627)NLEJ183752309 (DE-600)1471454-1 0048-3575 nnns volume:22 year:1984 number:1 pages:93-103 http://dx.doi.org/10.1016/0048-3575(84)90014-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 22 1984 1 93-103 |
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(DE-627)NLEJ183754883 (DE-599)GBVNLZ183754883 DE-627 ger DE-627 rakwb eng In vivo neurotoxic effects of dieldrin on giant nerve fibers and escape reflex function in the earthworm, Eisenia foetida 1984 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fiber conduction velocities were seen within a concentration range of 1.4 to 288 ppm. At a high concentration (288 ppm) the decreases in velocity occurred in as little as 90 min, but at low concentrations decreases in velocity occurred much more gradually. Other physiological and behavioral effects of dieldrin treatment included (i) after-discharges of giant fibers following brief mechanical stimulation, (ii) spontaneous bursts of giant fiber spikes, (iii) reductions in the amplitude of giant fiber-mediated muscle potentials, (iv) tonic spasms involving end-to-end shortening and body stiffening, (v) ataxia, and (vi) reduction in body weight. Thus, the in vivo effects of dieldrin in earthworms are characterized by a diverse and complex set of physiological and behavioral symptoms. Possible mechanisms underlying these effects are discussed in relation to the generally accepted mode of dieldrin action on synaptic transmission. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Drewes, C.D. oth Vining, E.P. oth in Pesticide Biochemistry and Physiology Amsterdam : Elsevier 22(1984), 1, Seite 93-103 (DE-627)NLEJ183752309 (DE-600)1471454-1 0048-3575 nnns volume:22 year:1984 number:1 pages:93-103 http://dx.doi.org/10.1016/0048-3575(84)90014-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 22 1984 1 93-103 |
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(DE-627)NLEJ183754883 (DE-599)GBVNLZ183754883 DE-627 ger DE-627 rakwb eng In vivo neurotoxic effects of dieldrin on giant nerve fibers and escape reflex function in the earthworm, Eisenia foetida 1984 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fiber conduction velocities were seen within a concentration range of 1.4 to 288 ppm. At a high concentration (288 ppm) the decreases in velocity occurred in as little as 90 min, but at low concentrations decreases in velocity occurred much more gradually. Other physiological and behavioral effects of dieldrin treatment included (i) after-discharges of giant fibers following brief mechanical stimulation, (ii) spontaneous bursts of giant fiber spikes, (iii) reductions in the amplitude of giant fiber-mediated muscle potentials, (iv) tonic spasms involving end-to-end shortening and body stiffening, (v) ataxia, and (vi) reduction in body weight. Thus, the in vivo effects of dieldrin in earthworms are characterized by a diverse and complex set of physiological and behavioral symptoms. Possible mechanisms underlying these effects are discussed in relation to the generally accepted mode of dieldrin action on synaptic transmission. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Drewes, C.D. oth Vining, E.P. oth in Pesticide Biochemistry and Physiology Amsterdam : Elsevier 22(1984), 1, Seite 93-103 (DE-627)NLEJ183752309 (DE-600)1471454-1 0048-3575 nnns volume:22 year:1984 number:1 pages:93-103 http://dx.doi.org/10.1016/0048-3575(84)90014-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 22 1984 1 93-103 |
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(DE-627)NLEJ183754883 (DE-599)GBVNLZ183754883 DE-627 ger DE-627 rakwb eng In vivo neurotoxic effects of dieldrin on giant nerve fibers and escape reflex function in the earthworm, Eisenia foetida 1984 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fiber conduction velocities were seen within a concentration range of 1.4 to 288 ppm. At a high concentration (288 ppm) the decreases in velocity occurred in as little as 90 min, but at low concentrations decreases in velocity occurred much more gradually. Other physiological and behavioral effects of dieldrin treatment included (i) after-discharges of giant fibers following brief mechanical stimulation, (ii) spontaneous bursts of giant fiber spikes, (iii) reductions in the amplitude of giant fiber-mediated muscle potentials, (iv) tonic spasms involving end-to-end shortening and body stiffening, (v) ataxia, and (vi) reduction in body weight. Thus, the in vivo effects of dieldrin in earthworms are characterized by a diverse and complex set of physiological and behavioral symptoms. Possible mechanisms underlying these effects are discussed in relation to the generally accepted mode of dieldrin action on synaptic transmission. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Drewes, C.D. oth Vining, E.P. oth in Pesticide Biochemistry and Physiology Amsterdam : Elsevier 22(1984), 1, Seite 93-103 (DE-627)NLEJ183752309 (DE-600)1471454-1 0048-3575 nnns volume:22 year:1984 number:1 pages:93-103 http://dx.doi.org/10.1016/0048-3575(84)90014-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 22 1984 1 93-103 |
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(DE-627)NLEJ183754883 (DE-599)GBVNLZ183754883 DE-627 ger DE-627 rakwb eng In vivo neurotoxic effects of dieldrin on giant nerve fibers and escape reflex function in the earthworm, Eisenia foetida 1984 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fiber conduction velocities were seen within a concentration range of 1.4 to 288 ppm. At a high concentration (288 ppm) the decreases in velocity occurred in as little as 90 min, but at low concentrations decreases in velocity occurred much more gradually. Other physiological and behavioral effects of dieldrin treatment included (i) after-discharges of giant fibers following brief mechanical stimulation, (ii) spontaneous bursts of giant fiber spikes, (iii) reductions in the amplitude of giant fiber-mediated muscle potentials, (iv) tonic spasms involving end-to-end shortening and body stiffening, (v) ataxia, and (vi) reduction in body weight. Thus, the in vivo effects of dieldrin in earthworms are characterized by a diverse and complex set of physiological and behavioral symptoms. Possible mechanisms underlying these effects are discussed in relation to the generally accepted mode of dieldrin action on synaptic transmission. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Drewes, C.D. oth Vining, E.P. oth in Pesticide Biochemistry and Physiology Amsterdam : Elsevier 22(1984), 1, Seite 93-103 (DE-627)NLEJ183752309 (DE-600)1471454-1 0048-3575 nnns volume:22 year:1984 number:1 pages:93-103 http://dx.doi.org/10.1016/0048-3575(84)90014-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 22 1984 1 93-103 |
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In vivo neurotoxic effects of dieldrin on giant nerve fibers and escape reflex function in the earthworm, Eisenia foetida |
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Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fiber conduction velocities were seen within a concentration range of 1.4 to 288 ppm. At a high concentration (288 ppm) the decreases in velocity occurred in as little as 90 min, but at low concentrations decreases in velocity occurred much more gradually. Other physiological and behavioral effects of dieldrin treatment included (i) after-discharges of giant fibers following brief mechanical stimulation, (ii) spontaneous bursts of giant fiber spikes, (iii) reductions in the amplitude of giant fiber-mediated muscle potentials, (iv) tonic spasms involving end-to-end shortening and body stiffening, (v) ataxia, and (vi) reduction in body weight. Thus, the in vivo effects of dieldrin in earthworms are characterized by a diverse and complex set of physiological and behavioral symptoms. Possible mechanisms underlying these effects are discussed in relation to the generally accepted mode of dieldrin action on synaptic transmission. |
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Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fiber conduction velocities were seen within a concentration range of 1.4 to 288 ppm. At a high concentration (288 ppm) the decreases in velocity occurred in as little as 90 min, but at low concentrations decreases in velocity occurred much more gradually. Other physiological and behavioral effects of dieldrin treatment included (i) after-discharges of giant fibers following brief mechanical stimulation, (ii) spontaneous bursts of giant fiber spikes, (iii) reductions in the amplitude of giant fiber-mediated muscle potentials, (iv) tonic spasms involving end-to-end shortening and body stiffening, (v) ataxia, and (vi) reduction in body weight. Thus, the in vivo effects of dieldrin in earthworms are characterized by a diverse and complex set of physiological and behavioral symptoms. Possible mechanisms underlying these effects are discussed in relation to the generally accepted mode of dieldrin action on synaptic transmission. |
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Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fiber conduction velocities were seen within a concentration range of 1.4 to 288 ppm. At a high concentration (288 ppm) the decreases in velocity occurred in as little as 90 min, but at low concentrations decreases in velocity occurred much more gradually. Other physiological and behavioral effects of dieldrin treatment included (i) after-discharges of giant fibers following brief mechanical stimulation, (ii) spontaneous bursts of giant fiber spikes, (iii) reductions in the amplitude of giant fiber-mediated muscle potentials, (iv) tonic spasms involving end-to-end shortening and body stiffening, (v) ataxia, and (vi) reduction in body weight. Thus, the in vivo effects of dieldrin in earthworms are characterized by a diverse and complex set of physiological and behavioral symptoms. Possible mechanisms underlying these effects are discussed in relation to the generally accepted mode of dieldrin action on synaptic transmission. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ183754883</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210706212253.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070506s1984 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ183754883</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ183754883</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">In vivo neurotoxic effects of dieldrin on giant nerve fibers and escape reflex function in the earthworm, Eisenia foetida</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1984</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Neurotoxicological effects of dieldrin were assessed in adult earthworms, Eisenia foetida, using noninvasive electrophysiological recordings of escape reflex activity. After 48 hr body surface exposure to aqueous suspensions of dieldrin, dose-dependent reductions in medial and lateral giant nerve fiber conduction velocities were seen within a concentration range of 1.4 to 288 ppm. At a high concentration (288 ppm) the decreases in velocity occurred in as little as 90 min, but at low concentrations decreases in velocity occurred much more gradually. Other physiological and behavioral effects of dieldrin treatment included (i) after-discharges of giant fibers following brief mechanical stimulation, (ii) spontaneous bursts of giant fiber spikes, (iii) reductions in the amplitude of giant fiber-mediated muscle potentials, (iv) tonic spasms involving end-to-end shortening and body stiffening, (v) ataxia, and (vi) reduction in body weight. Thus, the in vivo effects of dieldrin in earthworms are characterized by a diverse and complex set of physiological and behavioral symptoms. Possible mechanisms underlying these effects are discussed in relation to the generally accepted mode of dieldrin action on synaptic transmission.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Drewes, C.D.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Vining, E.P.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Pesticide Biochemistry and Physiology</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">22(1984), 1, Seite 93-103</subfield><subfield code="w">(DE-627)NLEJ183752309</subfield><subfield code="w">(DE-600)1471454-1</subfield><subfield code="x">0048-3575</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:22</subfield><subfield code="g">year:1984</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:93-103</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1016/0048-3575(84)90014-2</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">22</subfield><subfield code="j">1984</subfield><subfield code="e">1</subfield><subfield code="h">93-103</subfield></datafield></record></collection>
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