Tetanus toxin affects the K^+-stimulated release of catecholamines from nerve growth factor-treated PC12 cells
Tetanus toxin specifically binds to neuronal surfaces and interferes with the release of transmitters. The effect of tetanus toxin pretreatment of PC12 cell line, taken as a model of neuronal cells in culture, was studied and found that it depresses depolarization-dependent catecholamines secretion....
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| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1985 |
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| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
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| Übergeordnetes Werk: |
in: Biochemical and Biophysical Research Communications - Amsterdam : Elsevier, 128(1985), 1, Seite 249-256 |
| Übergeordnetes Werk: |
volume:128 ; year:1985 ; number:1 ; pages:249-256 |
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| 245 | 1 | 0 | |a Tetanus toxin affects the K^+-stimulated release of catecholamines from nerve growth factor-treated PC12 cells |
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| 520 | |a Tetanus toxin specifically binds to neuronal surfaces and interferes with the release of transmitters. The effect of tetanus toxin pretreatment of PC12 cell line, taken as a model of neuronal cells in culture, was studied and found that it depresses depolarization-dependent catecholamines secretion. This effect is limited to PC12 cells fully differentiated by the action of Nerve Growth Factor (NGF) and is indicative of the expression of specific binding sites for tetanus toxin during transition from the undifferentiated state. Specific binding of [^1^2^5I] tetanus toxin to NGF-treated PC12 was demonstrable. The toxin has no effect on the ^4^5Ca accumulation coupled with the depolarization dependent release of catecholamines. | ||
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(DE-627)NLEJ184144795 (DE-599)GBVNLZ184144795 DE-627 ger DE-627 rakwb eng Tetanus toxin affects the K^+-stimulated release of catecholamines from nerve growth factor-treated PC12 cells 1985 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Tetanus toxin specifically binds to neuronal surfaces and interferes with the release of transmitters. The effect of tetanus toxin pretreatment of PC12 cell line, taken as a model of neuronal cells in culture, was studied and found that it depresses depolarization-dependent catecholamines secretion. This effect is limited to PC12 cells fully differentiated by the action of Nerve Growth Factor (NGF) and is indicative of the expression of specific binding sites for tetanus toxin during transition from the undifferentiated state. Specific binding of [^1^2^5I] tetanus toxin to NGF-treated PC12 was demonstrable. The toxin has no effect on the ^4^5Ca accumulation coupled with the depolarization dependent release of catecholamines. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Figliomeni, B. oth Grasso, A. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 128(1985), 1, Seite 249-256 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:128 year:1985 number:1 pages:249-256 http://dx.doi.org/10.1016/0006-291X(85)91671-7 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 128 1985 1 249-256 |
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(DE-627)NLEJ184144795 (DE-599)GBVNLZ184144795 DE-627 ger DE-627 rakwb eng Tetanus toxin affects the K^+-stimulated release of catecholamines from nerve growth factor-treated PC12 cells 1985 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Tetanus toxin specifically binds to neuronal surfaces and interferes with the release of transmitters. The effect of tetanus toxin pretreatment of PC12 cell line, taken as a model of neuronal cells in culture, was studied and found that it depresses depolarization-dependent catecholamines secretion. This effect is limited to PC12 cells fully differentiated by the action of Nerve Growth Factor (NGF) and is indicative of the expression of specific binding sites for tetanus toxin during transition from the undifferentiated state. Specific binding of [^1^2^5I] tetanus toxin to NGF-treated PC12 was demonstrable. The toxin has no effect on the ^4^5Ca accumulation coupled with the depolarization dependent release of catecholamines. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Figliomeni, B. oth Grasso, A. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 128(1985), 1, Seite 249-256 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:128 year:1985 number:1 pages:249-256 http://dx.doi.org/10.1016/0006-291X(85)91671-7 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 128 1985 1 249-256 |
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(DE-627)NLEJ184144795 (DE-599)GBVNLZ184144795 DE-627 ger DE-627 rakwb eng Tetanus toxin affects the K^+-stimulated release of catecholamines from nerve growth factor-treated PC12 cells 1985 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Tetanus toxin specifically binds to neuronal surfaces and interferes with the release of transmitters. The effect of tetanus toxin pretreatment of PC12 cell line, taken as a model of neuronal cells in culture, was studied and found that it depresses depolarization-dependent catecholamines secretion. This effect is limited to PC12 cells fully differentiated by the action of Nerve Growth Factor (NGF) and is indicative of the expression of specific binding sites for tetanus toxin during transition from the undifferentiated state. Specific binding of [^1^2^5I] tetanus toxin to NGF-treated PC12 was demonstrable. The toxin has no effect on the ^4^5Ca accumulation coupled with the depolarization dependent release of catecholamines. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Figliomeni, B. oth Grasso, A. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 128(1985), 1, Seite 249-256 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:128 year:1985 number:1 pages:249-256 http://dx.doi.org/10.1016/0006-291X(85)91671-7 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 128 1985 1 249-256 |
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(DE-627)NLEJ184144795 (DE-599)GBVNLZ184144795 DE-627 ger DE-627 rakwb eng Tetanus toxin affects the K^+-stimulated release of catecholamines from nerve growth factor-treated PC12 cells 1985 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Tetanus toxin specifically binds to neuronal surfaces and interferes with the release of transmitters. The effect of tetanus toxin pretreatment of PC12 cell line, taken as a model of neuronal cells in culture, was studied and found that it depresses depolarization-dependent catecholamines secretion. This effect is limited to PC12 cells fully differentiated by the action of Nerve Growth Factor (NGF) and is indicative of the expression of specific binding sites for tetanus toxin during transition from the undifferentiated state. Specific binding of [^1^2^5I] tetanus toxin to NGF-treated PC12 was demonstrable. The toxin has no effect on the ^4^5Ca accumulation coupled with the depolarization dependent release of catecholamines. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Figliomeni, B. oth Grasso, A. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 128(1985), 1, Seite 249-256 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:128 year:1985 number:1 pages:249-256 http://dx.doi.org/10.1016/0006-291X(85)91671-7 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 128 1985 1 249-256 |
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(DE-627)NLEJ184144795 (DE-599)GBVNLZ184144795 DE-627 ger DE-627 rakwb eng Tetanus toxin affects the K^+-stimulated release of catecholamines from nerve growth factor-treated PC12 cells 1985 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Tetanus toxin specifically binds to neuronal surfaces and interferes with the release of transmitters. The effect of tetanus toxin pretreatment of PC12 cell line, taken as a model of neuronal cells in culture, was studied and found that it depresses depolarization-dependent catecholamines secretion. This effect is limited to PC12 cells fully differentiated by the action of Nerve Growth Factor (NGF) and is indicative of the expression of specific binding sites for tetanus toxin during transition from the undifferentiated state. Specific binding of [^1^2^5I] tetanus toxin to NGF-treated PC12 was demonstrable. The toxin has no effect on the ^4^5Ca accumulation coupled with the depolarization dependent release of catecholamines. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Figliomeni, B. oth Grasso, A. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 128(1985), 1, Seite 249-256 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:128 year:1985 number:1 pages:249-256 http://dx.doi.org/10.1016/0006-291X(85)91671-7 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 128 1985 1 249-256 |
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tetanus toxin affects the k^+-stimulated release of catecholamines from nerve growth factor-treated pc12 cells |
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Tetanus toxin affects the K^+-stimulated release of catecholamines from nerve growth factor-treated PC12 cells |
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Tetanus toxin specifically binds to neuronal surfaces and interferes with the release of transmitters. The effect of tetanus toxin pretreatment of PC12 cell line, taken as a model of neuronal cells in culture, was studied and found that it depresses depolarization-dependent catecholamines secretion. This effect is limited to PC12 cells fully differentiated by the action of Nerve Growth Factor (NGF) and is indicative of the expression of specific binding sites for tetanus toxin during transition from the undifferentiated state. Specific binding of [^1^2^5I] tetanus toxin to NGF-treated PC12 was demonstrable. The toxin has no effect on the ^4^5Ca accumulation coupled with the depolarization dependent release of catecholamines. |
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Tetanus toxin specifically binds to neuronal surfaces and interferes with the release of transmitters. The effect of tetanus toxin pretreatment of PC12 cell line, taken as a model of neuronal cells in culture, was studied and found that it depresses depolarization-dependent catecholamines secretion. This effect is limited to PC12 cells fully differentiated by the action of Nerve Growth Factor (NGF) and is indicative of the expression of specific binding sites for tetanus toxin during transition from the undifferentiated state. Specific binding of [^1^2^5I] tetanus toxin to NGF-treated PC12 was demonstrable. The toxin has no effect on the ^4^5Ca accumulation coupled with the depolarization dependent release of catecholamines. |
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Tetanus toxin specifically binds to neuronal surfaces and interferes with the release of transmitters. The effect of tetanus toxin pretreatment of PC12 cell line, taken as a model of neuronal cells in culture, was studied and found that it depresses depolarization-dependent catecholamines secretion. This effect is limited to PC12 cells fully differentiated by the action of Nerve Growth Factor (NGF) and is indicative of the expression of specific binding sites for tetanus toxin during transition from the undifferentiated state. Specific binding of [^1^2^5I] tetanus toxin to NGF-treated PC12 was demonstrable. The toxin has no effect on the ^4^5Ca accumulation coupled with the depolarization dependent release of catecholamines. |
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