Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin
The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (C...
Ausführliche Beschreibung
Autor*in: |
---|
Format: |
E-Artikel |
---|---|
Sprache: |
Englisch |
Erschienen: |
1989 |
---|
Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
---|---|
Übergeordnetes Werk: |
in: Biochemical and Biophysical Research Communications - Amsterdam : Elsevier, 161(1989), 1, Seite 221-228 |
Übergeordnetes Werk: |
volume:161 ; year:1989 ; number:1 ; pages:221-228 |
Links: |
---|
Katalog-ID: |
NLEJ184191343 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | NLEJ184191343 | ||
003 | DE-627 | ||
005 | 20210706223532.0 | ||
007 | cr uuu---uuuuu | ||
008 | 070506s1989 xx |||||o 00| ||eng c | ||
035 | |a (DE-627)NLEJ184191343 | ||
035 | |a (DE-599)GBVNLZ184191343 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
245 | 1 | 0 | |a Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin |
264 | 1 | |c 1989 | |
336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
337 | |a nicht spezifiziert |b z |2 rdamedia | ||
338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
520 | |a The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus. | ||
533 | |f Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 | ||
700 | 1 | |a Sweep, C.G.J. |4 oth | |
700 | 1 | |a Wiegant, V.M. |4 oth | |
773 | 0 | 8 | |i in |t Biochemical and Biophysical Research Communications |d Amsterdam : Elsevier |g 161(1989), 1, Seite 221-228 |w (DE-627)NLEJ176855645 |w (DE-600)1461396-7 |x 0006-291X |7 nnns |
773 | 1 | 8 | |g volume:161 |g year:1989 |g number:1 |g pages:221-228 |
856 | 4 | 0 | |u http://dx.doi.org/10.1016/0006-291X(89)91584-2 |
912 | |a GBV_USEFLAG_H | ||
912 | |a ZDB-1-SDJ | ||
912 | |a GBV_NL_ARTICLE | ||
951 | |a AR | ||
952 | |d 161 |j 1989 |e 1 |h 221-228 |
matchkey_str |
article:0006291X:1989----::eesoedrhnmuoeciiyrmaptiaynhptaauivtofetoiortrnloaieotctoi |
---|---|
hierarchy_sort_str |
1989 |
publishDate |
1989 |
allfields |
(DE-627)NLEJ184191343 (DE-599)GBVNLZ184191343 DE-627 ger DE-627 rakwb eng Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin 1989 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Sweep, C.G.J. oth Wiegant, V.M. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 161(1989), 1, Seite 221-228 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:161 year:1989 number:1 pages:221-228 http://dx.doi.org/10.1016/0006-291X(89)91584-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 161 1989 1 221-228 |
spelling |
(DE-627)NLEJ184191343 (DE-599)GBVNLZ184191343 DE-627 ger DE-627 rakwb eng Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin 1989 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Sweep, C.G.J. oth Wiegant, V.M. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 161(1989), 1, Seite 221-228 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:161 year:1989 number:1 pages:221-228 http://dx.doi.org/10.1016/0006-291X(89)91584-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 161 1989 1 221-228 |
allfields_unstemmed |
(DE-627)NLEJ184191343 (DE-599)GBVNLZ184191343 DE-627 ger DE-627 rakwb eng Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin 1989 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Sweep, C.G.J. oth Wiegant, V.M. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 161(1989), 1, Seite 221-228 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:161 year:1989 number:1 pages:221-228 http://dx.doi.org/10.1016/0006-291X(89)91584-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 161 1989 1 221-228 |
allfieldsGer |
(DE-627)NLEJ184191343 (DE-599)GBVNLZ184191343 DE-627 ger DE-627 rakwb eng Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin 1989 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Sweep, C.G.J. oth Wiegant, V.M. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 161(1989), 1, Seite 221-228 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:161 year:1989 number:1 pages:221-228 http://dx.doi.org/10.1016/0006-291X(89)91584-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 161 1989 1 221-228 |
allfieldsSound |
(DE-627)NLEJ184191343 (DE-599)GBVNLZ184191343 DE-627 ger DE-627 rakwb eng Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin 1989 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Sweep, C.G.J. oth Wiegant, V.M. oth in Biochemical and Biophysical Research Communications Amsterdam : Elsevier 161(1989), 1, Seite 221-228 (DE-627)NLEJ176855645 (DE-600)1461396-7 0006-291X nnns volume:161 year:1989 number:1 pages:221-228 http://dx.doi.org/10.1016/0006-291X(89)91584-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 161 1989 1 221-228 |
language |
English |
source |
in Biochemical and Biophysical Research Communications 161(1989), 1, Seite 221-228 volume:161 year:1989 number:1 pages:221-228 |
sourceStr |
in Biochemical and Biophysical Research Communications 161(1989), 1, Seite 221-228 volume:161 year:1989 number:1 pages:221-228 |
format_phy_str_mv |
Article |
institution |
findex.gbv.de |
isfreeaccess_bool |
false |
container_title |
Biochemical and Biophysical Research Communications |
authorswithroles_txt_mv |
Sweep, C.G.J. @@oth@@ Wiegant, V.M. @@oth@@ |
publishDateDaySort_date |
1989-01-01T00:00:00Z |
hierarchy_top_id |
NLEJ176855645 |
id |
NLEJ184191343 |
language_de |
englisch |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ184191343</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210706223532.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070506s1989 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ184191343</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ184191343</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1989</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sweep, C.G.J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Wiegant, V.M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Biochemical and Biophysical Research Communications</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">161(1989), 1, Seite 221-228</subfield><subfield code="w">(DE-627)NLEJ176855645</subfield><subfield code="w">(DE-600)1461396-7</subfield><subfield code="x">0006-291X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:161</subfield><subfield code="g">year:1989</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:221-228</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1016/0006-291X(89)91584-2</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">161</subfield><subfield code="j">1989</subfield><subfield code="e">1</subfield><subfield code="h">221-228</subfield></datafield></record></collection>
|
series2 |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ176855645 |
format |
electronic Article |
delete_txt_mv |
keep |
collection |
NL |
remote_str |
true |
illustrated |
Not Illustrated |
issn |
0006-291X |
topic_title |
Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin |
format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
format_main_str_mv |
Text Zeitschrift/Artikel |
carriertype_str_mv |
zu |
author2_variant |
c s cs v w vw |
hierarchy_parent_title |
Biochemical and Biophysical Research Communications |
hierarchy_parent_id |
NLEJ176855645 |
hierarchy_top_title |
Biochemical and Biophysical Research Communications |
isfreeaccess_txt |
false |
familylinks_str_mv |
(DE-627)NLEJ176855645 (DE-600)1461396-7 |
title |
Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin |
spellingShingle |
Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin |
ctrlnum |
(DE-627)NLEJ184191343 (DE-599)GBVNLZ184191343 |
title_full |
Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin |
journal |
Biochemical and Biophysical Research Communications |
journalStr |
Biochemical and Biophysical Research Communications |
lang_code |
eng |
isOA_bool |
false |
recordtype |
marc |
publishDateSort |
1989 |
contenttype_str_mv |
zzz |
container_start_page |
221 |
container_volume |
161 |
format_se |
Elektronische Aufsätze |
title_sort |
release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin |
title_auth |
Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin |
abstract |
The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus. |
abstractGer |
The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus. |
abstract_unstemmed |
The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus. |
collection_details |
GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE |
container_issue |
1 |
title_short |
Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin |
url |
http://dx.doi.org/10.1016/0006-291X(89)91584-2 |
remote_bool |
true |
author2 |
Sweep, C.G.J. Wiegant, V.M. |
author2Str |
Sweep, C.G.J. Wiegant, V.M. |
ppnlink |
NLEJ176855645 |
mediatype_str_mv |
z |
isOA_txt |
false |
hochschulschrift_bool |
false |
author2_role |
oth oth |
up_date |
2024-07-06T00:29:20.872Z |
_version_ |
1803787447434215424 |
fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ184191343</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210706223532.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070506s1989 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ184191343</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ184191343</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Release of β-endorphin-immunoreactivity from rat pituitary and hypothalamus in vitro: Effects of isoproterenol, dopamine, corticotropin-releasing factor and agrinine^8-vasopressin</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1989</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The release of β-endorphin-immunoreactivity (βE-IR) from rat pituitary anterior lobe (AL) quarters, neurointermediate lobes (NILs), and hypothalamic fragments was investigated in vitro. The β-adrenoceptor agonist isoproterenol (ISO) and the hypothalamic neurohormone corticotropin-releasing factor (CRF) concentration-dependently stimulated the release of βE-IR from superfused AL quarters and NILs, but not from incubated hypothalamic fragments. Dopamine (DA) inhibited the release of βE-IR from NILs and hypothalamic tissue in a concentration-dependent manner, whereas it did not affect the release from AL quarters. Arginine^8-vasopressin (AVP) stimulated the release of βE-IR from AL quarters and hypothalamic fragments, but did not affect the release from NILs. The data indicate that the release of βE-IR from cells in the pituitary lobes and in the hypothalamus is differentially regulated, but that common principles are involved. In particular, the results provide first direct evidence for an action of vasopressin as a stimulator of the release of POMC-derived peptides in the hypothalamus.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sweep, C.G.J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Wiegant, V.M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Biochemical and Biophysical Research Communications</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">161(1989), 1, Seite 221-228</subfield><subfield code="w">(DE-627)NLEJ176855645</subfield><subfield code="w">(DE-600)1461396-7</subfield><subfield code="x">0006-291X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:161</subfield><subfield code="g">year:1989</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:221-228</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1016/0006-291X(89)91584-2</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">161</subfield><subfield code="j">1989</subfield><subfield code="e">1</subfield><subfield code="h">221-228</subfield></datafield></record></collection>
|
score |
7.3996468 |