Cell surface changes associated with EGF and insulin-induced cell adhesion
The ability of insulin and epidermal growth factor (EGF) to restore cell surface function in cells damaged by serum deprivation has been examined. Both insulin (10^-^7 M) and EGF (10^-^8 M), when added for 2 h, resulted in reattachment of cells to the culture dish; with insulin, attachment was assoc...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
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| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
1981 |
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| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
|---|---|
| Übergeordnetes Werk: |
in: Experimental Cell Research - Amsterdam : Elsevier, 133(1981), 1, Seite 227-235 |
| Übergeordnetes Werk: |
volume:133 ; year:1981 ; number:1 ; pages:227-235 |
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NLEJ184343909 |
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| 520 | |a The ability of insulin and epidermal growth factor (EGF) to restore cell surface function in cells damaged by serum deprivation has been examined. Both insulin (10^-^7 M) and EGF (10^-^8 M), when added for 2 h, resulted in reattachment of cells to the culture dish; with insulin, attachment was associated with increased amino acid uptake. Both hormones caused an increase in sialic acid and in free sulfhydryl groups associated with the cell membrane. The mobility of concanavalin A (Con A) on the upper cell surface was increased by EGF, and to a lesser extent by insulin. The effects of insulin and EGF on adhesion appear to be regulated by specific receptors for these hormones. | ||
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(DE-627)NLEJ184343909 (DE-599)GBVNLZ184343909 DE-627 ger DE-627 rakwb eng Cell surface changes associated with EGF and insulin-induced cell adhesion 1981 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The ability of insulin and epidermal growth factor (EGF) to restore cell surface function in cells damaged by serum deprivation has been examined. Both insulin (10^-^7 M) and EGF (10^-^8 M), when added for 2 h, resulted in reattachment of cells to the culture dish; with insulin, attachment was associated with increased amino acid uptake. Both hormones caused an increase in sialic acid and in free sulfhydryl groups associated with the cell membrane. The mobility of concanavalin A (Con A) on the upper cell surface was increased by EGF, and to a lesser extent by insulin. The effects of insulin and EGF on adhesion appear to be regulated by specific receptors for these hormones. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Berliner, J.A. oth Aharanov, A. oth Pruss, R. oth in Experimental Cell Research Amsterdam : Elsevier 133(1981), 1, Seite 227-235 (DE-627)NLEJ177031808 (DE-600)1466780-0 0014-4827 nnns volume:133 year:1981 number:1 pages:227-235 http://dx.doi.org/10.1016/0014-4827(81)90371-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 133 1981 1 227-235 |
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(DE-627)NLEJ184343909 (DE-599)GBVNLZ184343909 DE-627 ger DE-627 rakwb eng Cell surface changes associated with EGF and insulin-induced cell adhesion 1981 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The ability of insulin and epidermal growth factor (EGF) to restore cell surface function in cells damaged by serum deprivation has been examined. Both insulin (10^-^7 M) and EGF (10^-^8 M), when added for 2 h, resulted in reattachment of cells to the culture dish; with insulin, attachment was associated with increased amino acid uptake. Both hormones caused an increase in sialic acid and in free sulfhydryl groups associated with the cell membrane. The mobility of concanavalin A (Con A) on the upper cell surface was increased by EGF, and to a lesser extent by insulin. The effects of insulin and EGF on adhesion appear to be regulated by specific receptors for these hormones. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Berliner, J.A. oth Aharanov, A. oth Pruss, R. oth in Experimental Cell Research Amsterdam : Elsevier 133(1981), 1, Seite 227-235 (DE-627)NLEJ177031808 (DE-600)1466780-0 0014-4827 nnns volume:133 year:1981 number:1 pages:227-235 http://dx.doi.org/10.1016/0014-4827(81)90371-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 133 1981 1 227-235 |
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(DE-627)NLEJ184343909 (DE-599)GBVNLZ184343909 DE-627 ger DE-627 rakwb eng Cell surface changes associated with EGF and insulin-induced cell adhesion 1981 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The ability of insulin and epidermal growth factor (EGF) to restore cell surface function in cells damaged by serum deprivation has been examined. Both insulin (10^-^7 M) and EGF (10^-^8 M), when added for 2 h, resulted in reattachment of cells to the culture dish; with insulin, attachment was associated with increased amino acid uptake. Both hormones caused an increase in sialic acid and in free sulfhydryl groups associated with the cell membrane. The mobility of concanavalin A (Con A) on the upper cell surface was increased by EGF, and to a lesser extent by insulin. The effects of insulin and EGF on adhesion appear to be regulated by specific receptors for these hormones. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Berliner, J.A. oth Aharanov, A. oth Pruss, R. oth in Experimental Cell Research Amsterdam : Elsevier 133(1981), 1, Seite 227-235 (DE-627)NLEJ177031808 (DE-600)1466780-0 0014-4827 nnns volume:133 year:1981 number:1 pages:227-235 http://dx.doi.org/10.1016/0014-4827(81)90371-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 133 1981 1 227-235 |
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(DE-627)NLEJ184343909 (DE-599)GBVNLZ184343909 DE-627 ger DE-627 rakwb eng Cell surface changes associated with EGF and insulin-induced cell adhesion 1981 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The ability of insulin and epidermal growth factor (EGF) to restore cell surface function in cells damaged by serum deprivation has been examined. Both insulin (10^-^7 M) and EGF (10^-^8 M), when added for 2 h, resulted in reattachment of cells to the culture dish; with insulin, attachment was associated with increased amino acid uptake. Both hormones caused an increase in sialic acid and in free sulfhydryl groups associated with the cell membrane. The mobility of concanavalin A (Con A) on the upper cell surface was increased by EGF, and to a lesser extent by insulin. The effects of insulin and EGF on adhesion appear to be regulated by specific receptors for these hormones. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Berliner, J.A. oth Aharanov, A. oth Pruss, R. oth in Experimental Cell Research Amsterdam : Elsevier 133(1981), 1, Seite 227-235 (DE-627)NLEJ177031808 (DE-600)1466780-0 0014-4827 nnns volume:133 year:1981 number:1 pages:227-235 http://dx.doi.org/10.1016/0014-4827(81)90371-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 133 1981 1 227-235 |
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(DE-627)NLEJ184343909 (DE-599)GBVNLZ184343909 DE-627 ger DE-627 rakwb eng Cell surface changes associated with EGF and insulin-induced cell adhesion 1981 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The ability of insulin and epidermal growth factor (EGF) to restore cell surface function in cells damaged by serum deprivation has been examined. Both insulin (10^-^7 M) and EGF (10^-^8 M), when added for 2 h, resulted in reattachment of cells to the culture dish; with insulin, attachment was associated with increased amino acid uptake. Both hormones caused an increase in sialic acid and in free sulfhydryl groups associated with the cell membrane. The mobility of concanavalin A (Con A) on the upper cell surface was increased by EGF, and to a lesser extent by insulin. The effects of insulin and EGF on adhesion appear to be regulated by specific receptors for these hormones. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Berliner, J.A. oth Aharanov, A. oth Pruss, R. oth in Experimental Cell Research Amsterdam : Elsevier 133(1981), 1, Seite 227-235 (DE-627)NLEJ177031808 (DE-600)1466780-0 0014-4827 nnns volume:133 year:1981 number:1 pages:227-235 http://dx.doi.org/10.1016/0014-4827(81)90371-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 133 1981 1 227-235 |
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Cell surface changes associated with EGF and insulin-induced cell adhesion |
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The ability of insulin and epidermal growth factor (EGF) to restore cell surface function in cells damaged by serum deprivation has been examined. Both insulin (10^-^7 M) and EGF (10^-^8 M), when added for 2 h, resulted in reattachment of cells to the culture dish; with insulin, attachment was associated with increased amino acid uptake. Both hormones caused an increase in sialic acid and in free sulfhydryl groups associated with the cell membrane. The mobility of concanavalin A (Con A) on the upper cell surface was increased by EGF, and to a lesser extent by insulin. The effects of insulin and EGF on adhesion appear to be regulated by specific receptors for these hormones. |
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The ability of insulin and epidermal growth factor (EGF) to restore cell surface function in cells damaged by serum deprivation has been examined. Both insulin (10^-^7 M) and EGF (10^-^8 M), when added for 2 h, resulted in reattachment of cells to the culture dish; with insulin, attachment was associated with increased amino acid uptake. Both hormones caused an increase in sialic acid and in free sulfhydryl groups associated with the cell membrane. The mobility of concanavalin A (Con A) on the upper cell surface was increased by EGF, and to a lesser extent by insulin. The effects of insulin and EGF on adhesion appear to be regulated by specific receptors for these hormones. |
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The ability of insulin and epidermal growth factor (EGF) to restore cell surface function in cells damaged by serum deprivation has been examined. Both insulin (10^-^7 M) and EGF (10^-^8 M), when added for 2 h, resulted in reattachment of cells to the culture dish; with insulin, attachment was associated with increased amino acid uptake. Both hormones caused an increase in sialic acid and in free sulfhydryl groups associated with the cell membrane. The mobility of concanavalin A (Con A) on the upper cell surface was increased by EGF, and to a lesser extent by insulin. The effects of insulin and EGF on adhesion appear to be regulated by specific receptors for these hormones. |
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