Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs
Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaade...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
1975 |
|---|
| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
|---|---|
| Übergeordnetes Werk: |
in: BBA Section Nucleic Acids And Protein Synthesis - Amsterdam : Elsevier, 383(1975), 3, Seite 236-241 |
| Übergeordnetes Werk: |
volume:383 ; year:1975 ; number:3 ; pages:236-241 |
| Links: |
|---|
| Katalog-ID: |
NLEJ185887813 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLEJ185887813 | ||
| 003 | DE-627 | ||
| 005 | 20210707031118.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 070506s1975 xx |||||o 00| ||eng c | ||
| 035 | |a (DE-627)NLEJ185887813 | ||
| 035 | |a (DE-599)GBVNLZ185887813 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 245 | 1 | 0 | |a Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs |
| 264 | 1 | |c 1975 | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes. | ||
| 533 | |f Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 | ||
| 700 | 1 | |a Ohtsuka, E. |4 oth | |
| 700 | 1 | |a Nagura, T. |4 oth | |
| 700 | 1 | |a Shimokawa, K. |4 oth | |
| 700 | 1 | |a Nishikawa, S. |4 oth | |
| 700 | 1 | |a Ikehara, M. |4 oth | |
| 773 | 0 | 8 | |i in |t BBA Section Nucleic Acids And Protein Synthesis |d Amsterdam : Elsevier |g 383(1975), 3, Seite 236-241 |w (DE-627)NLEJ185870457 |w (DE-600)2209441-6 |x 0005-2787 |7 nnns |
| 773 | 1 | 8 | |g volume:383 |g year:1975 |g number:3 |g pages:236-241 |
| 856 | 4 | 0 | |u http://linkinghub.elsevier.com/retrieve/pii/0005-2787(75)90052-0 |
| 912 | |a GBV_USEFLAG_H | ||
| 912 | |a ZDB-1-SDJ | ||
| 912 | |a GBV_NL_ARTICLE | ||
| 951 | |a AR | ||
| 952 | |d 383 |j 1975 |e 3 |h 236-241 | ||
| matchkey_str |
article:00052787:1975----::oyuloiexvisiuainfhbnigfmnaytntrbsmsy |
|---|---|
| hierarchy_sort_str |
1975 |
| publishDate |
1975 |
| allfields |
(DE-627)NLEJ185887813 (DE-599)GBVNLZ185887813 DE-627 ger DE-627 rakwb eng Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs 1975 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Ohtsuka, E. oth Nagura, T. oth Shimokawa, K. oth Nishikawa, S. oth Ikehara, M. oth in BBA Section Nucleic Acids And Protein Synthesis Amsterdam : Elsevier 383(1975), 3, Seite 236-241 (DE-627)NLEJ185870457 (DE-600)2209441-6 0005-2787 nnns volume:383 year:1975 number:3 pages:236-241 http://linkinghub.elsevier.com/retrieve/pii/0005-2787(75)90052-0 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 383 1975 3 236-241 |
| spelling |
(DE-627)NLEJ185887813 (DE-599)GBVNLZ185887813 DE-627 ger DE-627 rakwb eng Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs 1975 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Ohtsuka, E. oth Nagura, T. oth Shimokawa, K. oth Nishikawa, S. oth Ikehara, M. oth in BBA Section Nucleic Acids And Protein Synthesis Amsterdam : Elsevier 383(1975), 3, Seite 236-241 (DE-627)NLEJ185870457 (DE-600)2209441-6 0005-2787 nnns volume:383 year:1975 number:3 pages:236-241 http://linkinghub.elsevier.com/retrieve/pii/0005-2787(75)90052-0 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 383 1975 3 236-241 |
| allfields_unstemmed |
(DE-627)NLEJ185887813 (DE-599)GBVNLZ185887813 DE-627 ger DE-627 rakwb eng Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs 1975 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Ohtsuka, E. oth Nagura, T. oth Shimokawa, K. oth Nishikawa, S. oth Ikehara, M. oth in BBA Section Nucleic Acids And Protein Synthesis Amsterdam : Elsevier 383(1975), 3, Seite 236-241 (DE-627)NLEJ185870457 (DE-600)2209441-6 0005-2787 nnns volume:383 year:1975 number:3 pages:236-241 http://linkinghub.elsevier.com/retrieve/pii/0005-2787(75)90052-0 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 383 1975 3 236-241 |
| allfieldsGer |
(DE-627)NLEJ185887813 (DE-599)GBVNLZ185887813 DE-627 ger DE-627 rakwb eng Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs 1975 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Ohtsuka, E. oth Nagura, T. oth Shimokawa, K. oth Nishikawa, S. oth Ikehara, M. oth in BBA Section Nucleic Acids And Protein Synthesis Amsterdam : Elsevier 383(1975), 3, Seite 236-241 (DE-627)NLEJ185870457 (DE-600)2209441-6 0005-2787 nnns volume:383 year:1975 number:3 pages:236-241 http://linkinghub.elsevier.com/retrieve/pii/0005-2787(75)90052-0 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 383 1975 3 236-241 |
| allfieldsSound |
(DE-627)NLEJ185887813 (DE-599)GBVNLZ185887813 DE-627 ger DE-627 rakwb eng Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs 1975 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Ohtsuka, E. oth Nagura, T. oth Shimokawa, K. oth Nishikawa, S. oth Ikehara, M. oth in BBA Section Nucleic Acids And Protein Synthesis Amsterdam : Elsevier 383(1975), 3, Seite 236-241 (DE-627)NLEJ185870457 (DE-600)2209441-6 0005-2787 nnns volume:383 year:1975 number:3 pages:236-241 http://linkinghub.elsevier.com/retrieve/pii/0005-2787(75)90052-0 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 383 1975 3 236-241 |
| language |
English |
| source |
in BBA Section Nucleic Acids And Protein Synthesis 383(1975), 3, Seite 236-241 volume:383 year:1975 number:3 pages:236-241 |
| sourceStr |
in BBA Section Nucleic Acids And Protein Synthesis 383(1975), 3, Seite 236-241 volume:383 year:1975 number:3 pages:236-241 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| isfreeaccess_bool |
false |
| container_title |
BBA Section Nucleic Acids And Protein Synthesis |
| authorswithroles_txt_mv |
Ohtsuka, E. @@oth@@ Nagura, T. @@oth@@ Shimokawa, K. @@oth@@ Nishikawa, S. @@oth@@ Ikehara, M. @@oth@@ |
| publishDateDaySort_date |
1975-01-01T00:00:00Z |
| hierarchy_top_id |
NLEJ185870457 |
| id |
NLEJ185887813 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ185887813</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707031118.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070506s1975 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ185887813</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ185887813</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1975</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ohtsuka, E.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nagura, T.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shimokawa, K.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nishikawa, S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ikehara, M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">BBA Section Nucleic Acids And Protein Synthesis</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">383(1975), 3, Seite 236-241</subfield><subfield code="w">(DE-627)NLEJ185870457</subfield><subfield code="w">(DE-600)2209441-6</subfield><subfield code="x">0005-2787</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:383</subfield><subfield code="g">year:1975</subfield><subfield code="g">number:3</subfield><subfield code="g">pages:236-241</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://linkinghub.elsevier.com/retrieve/pii/0005-2787(75)90052-0</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">383</subfield><subfield code="j">1975</subfield><subfield code="e">3</subfield><subfield code="h">236-241</subfield></datafield></record></collection>
|
| series2 |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ185870457 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| collection |
NL |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
0005-2787 |
| topic_title |
Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
e o eo t n tn k s ks s n sn m i mi |
| hierarchy_parent_title |
BBA Section Nucleic Acids And Protein Synthesis |
| hierarchy_parent_id |
NLEJ185870457 |
| hierarchy_top_title |
BBA Section Nucleic Acids And Protein Synthesis |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)NLEJ185870457 (DE-600)2209441-6 |
| title |
Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs |
| spellingShingle |
Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs |
| ctrlnum |
(DE-627)NLEJ185887813 (DE-599)GBVNLZ185887813 |
| title_full |
Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs |
| journal |
BBA Section Nucleic Acids And Protein Synthesis |
| journalStr |
BBA Section Nucleic Acids And Protein Synthesis |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
1975 |
| contenttype_str_mv |
zzz |
| container_start_page |
236 |
| container_volume |
383 |
| format_se |
Elektronische Aufsätze |
| title_sort |
polynucleotides - xxviii. stimulation of the binding of aminoacyl-trna to ribosomes by tri- and polynucleotide analogs |
| title_auth |
Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs |
| abstract |
Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes. |
| abstractGer |
Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes. |
| abstract_unstemmed |
Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes. |
| collection_details |
GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE |
| container_issue |
3 |
| title_short |
Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs |
| url |
http://linkinghub.elsevier.com/retrieve/pii/0005-2787(75)90052-0 |
| remote_bool |
true |
| author2 |
Ohtsuka, E. Nagura, T. Shimokawa, K. Nishikawa, S. Ikehara, M. |
| author2Str |
Ohtsuka, E. Nagura, T. Shimokawa, K. Nishikawa, S. Ikehara, M. |
| ppnlink |
NLEJ185870457 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth oth |
| up_date |
2024-07-06T05:21:29.289Z |
| _version_ |
1803805827309502464 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ185887813</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707031118.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070506s1975 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ185887813</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ185887813</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Polynucleotides - XXVIII. Stimulation of the binding of aminoacyl-tRNA to ribosomes by tri- and polynucleotide analogs</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1975</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Messenger activity of synthetic tri- and polynucleotide analogs was studied by binding of ^1^ ^4C-labeled aminoacyl-tRNAs to ribosomes in the presence of the analogs. Synthetic messengers used were: poly(A) analogs in which adenosine was replaced by tubercidine (I), 3-deazaadenosine (II), 1-deazaadenosine (III) and 2-methyladenosine (IV); copolymers of adenosine and aristeromycin (V); cyclic triadenylate (VI); the heptanucleotide of 6,2'-O-cyclouridine (VII); the pentanucleotide of 8,2'-S-cycloadenosine (VIIIa); A-U-G analogs in which adenosine was replaced by 8,2'-O- and S-cycloadenosine (VIII), 8,5'-O- and S-cycloadenosine (IX); 8-oxyadenosine (X); 8-bromoadenosine (XI) and formycine (XII). Among these oligo- and polynucleotides, analogs which contained nucleotides of anti conformation having appropriate bases for Watson-Crick type hydrogen bonding stimulated the binding of corresponding tRNAs to ribosomes.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ohtsuka, E.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nagura, T.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shimokawa, K.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nishikawa, S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ikehara, M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">BBA Section Nucleic Acids And Protein Synthesis</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">383(1975), 3, Seite 236-241</subfield><subfield code="w">(DE-627)NLEJ185870457</subfield><subfield code="w">(DE-600)2209441-6</subfield><subfield code="x">0005-2787</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:383</subfield><subfield code="g">year:1975</subfield><subfield code="g">number:3</subfield><subfield code="g">pages:236-241</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://linkinghub.elsevier.com/retrieve/pii/0005-2787(75)90052-0</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">383</subfield><subfield code="j">1975</subfield><subfield code="e">3</subfield><subfield code="h">236-241</subfield></datafield></record></collection>
|
| score |
7.3990374 |