Urinary enzyme analysis in renal allograft transplantation
The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patie...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
1986 |
|---|
| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
|---|---|
| Übergeordnetes Werk: |
in: Clinica Chimica Acta - Amsterdam : Elsevier, 160(1986), 2, Seite 137-144 |
| Übergeordnetes Werk: |
volume:160 ; year:1986 ; number:2 ; pages:137-144 |
| Links: |
|---|
| Katalog-ID: |
NLEJ186202113 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLEJ186202113 | ||
| 003 | DE-627 | ||
| 005 | 20210707040545.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 070506s1986 xx |||||o 00| ||eng c | ||
| 035 | |a (DE-627)NLEJ186202113 | ||
| 035 | |a (DE-599)GBVNLZ186202113 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 245 | 1 | 0 | |a Urinary enzyme analysis in renal allograft transplantation |
| 264 | 1 | |c 1986 | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model. | ||
| 533 | |f Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 | ||
| 700 | 1 | |a Kotanko, P. |4 oth | |
| 700 | 1 | |a Keiler, R. |4 oth | |
| 700 | 1 | |a Knabl, L. |4 oth | |
| 700 | 1 | |a Aulitzky, W. |4 oth | |
| 700 | 1 | |a Margreiter, R. |4 oth | |
| 700 | 1 | |a Gstraunthaler, G. |4 oth | |
| 700 | 1 | |a Pfaller, W. |4 oth | |
| 773 | 0 | 8 | |i in |t Clinica Chimica Acta |d Amsterdam : Elsevier |g 160(1986), 2, Seite 137-144 |w (DE-627)NLEJ184917921 |w (DE-600)1499920-1 |x 0009-8981 |7 nnns |
| 773 | 1 | 8 | |g volume:160 |g year:1986 |g number:2 |g pages:137-144 |
| 856 | 4 | 0 | |u http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90134-8 |
| 912 | |a GBV_USEFLAG_H | ||
| 912 | |a ZDB-1-SDJ | ||
| 912 | |a GBV_NL_ARTICLE | ||
| 951 | |a AR | ||
| 952 | |d 160 |j 1986 |e 2 |h 137-144 | ||
| matchkey_str |
article:00098981:1986----::rnrezmaayiirnllorft |
|---|---|
| hierarchy_sort_str |
1986 |
| publishDate |
1986 |
| allfields |
(DE-627)NLEJ186202113 (DE-599)GBVNLZ186202113 DE-627 ger DE-627 rakwb eng Urinary enzyme analysis in renal allograft transplantation 1986 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Kotanko, P. oth Keiler, R. oth Knabl, L. oth Aulitzky, W. oth Margreiter, R. oth Gstraunthaler, G. oth Pfaller, W. oth in Clinica Chimica Acta Amsterdam : Elsevier 160(1986), 2, Seite 137-144 (DE-627)NLEJ184917921 (DE-600)1499920-1 0009-8981 nnns volume:160 year:1986 number:2 pages:137-144 http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90134-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 160 1986 2 137-144 |
| spelling |
(DE-627)NLEJ186202113 (DE-599)GBVNLZ186202113 DE-627 ger DE-627 rakwb eng Urinary enzyme analysis in renal allograft transplantation 1986 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Kotanko, P. oth Keiler, R. oth Knabl, L. oth Aulitzky, W. oth Margreiter, R. oth Gstraunthaler, G. oth Pfaller, W. oth in Clinica Chimica Acta Amsterdam : Elsevier 160(1986), 2, Seite 137-144 (DE-627)NLEJ184917921 (DE-600)1499920-1 0009-8981 nnns volume:160 year:1986 number:2 pages:137-144 http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90134-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 160 1986 2 137-144 |
| allfields_unstemmed |
(DE-627)NLEJ186202113 (DE-599)GBVNLZ186202113 DE-627 ger DE-627 rakwb eng Urinary enzyme analysis in renal allograft transplantation 1986 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Kotanko, P. oth Keiler, R. oth Knabl, L. oth Aulitzky, W. oth Margreiter, R. oth Gstraunthaler, G. oth Pfaller, W. oth in Clinica Chimica Acta Amsterdam : Elsevier 160(1986), 2, Seite 137-144 (DE-627)NLEJ184917921 (DE-600)1499920-1 0009-8981 nnns volume:160 year:1986 number:2 pages:137-144 http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90134-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 160 1986 2 137-144 |
| allfieldsGer |
(DE-627)NLEJ186202113 (DE-599)GBVNLZ186202113 DE-627 ger DE-627 rakwb eng Urinary enzyme analysis in renal allograft transplantation 1986 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Kotanko, P. oth Keiler, R. oth Knabl, L. oth Aulitzky, W. oth Margreiter, R. oth Gstraunthaler, G. oth Pfaller, W. oth in Clinica Chimica Acta Amsterdam : Elsevier 160(1986), 2, Seite 137-144 (DE-627)NLEJ184917921 (DE-600)1499920-1 0009-8981 nnns volume:160 year:1986 number:2 pages:137-144 http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90134-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 160 1986 2 137-144 |
| allfieldsSound |
(DE-627)NLEJ186202113 (DE-599)GBVNLZ186202113 DE-627 ger DE-627 rakwb eng Urinary enzyme analysis in renal allograft transplantation 1986 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Kotanko, P. oth Keiler, R. oth Knabl, L. oth Aulitzky, W. oth Margreiter, R. oth Gstraunthaler, G. oth Pfaller, W. oth in Clinica Chimica Acta Amsterdam : Elsevier 160(1986), 2, Seite 137-144 (DE-627)NLEJ184917921 (DE-600)1499920-1 0009-8981 nnns volume:160 year:1986 number:2 pages:137-144 http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90134-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 160 1986 2 137-144 |
| language |
English |
| source |
in Clinica Chimica Acta 160(1986), 2, Seite 137-144 volume:160 year:1986 number:2 pages:137-144 |
| sourceStr |
in Clinica Chimica Acta 160(1986), 2, Seite 137-144 volume:160 year:1986 number:2 pages:137-144 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| isfreeaccess_bool |
false |
| container_title |
Clinica Chimica Acta |
| authorswithroles_txt_mv |
Kotanko, P. @@oth@@ Keiler, R. @@oth@@ Knabl, L. @@oth@@ Aulitzky, W. @@oth@@ Margreiter, R. @@oth@@ Gstraunthaler, G. @@oth@@ Pfaller, W. @@oth@@ |
| publishDateDaySort_date |
1986-01-01T00:00:00Z |
| hierarchy_top_id |
NLEJ184917921 |
| id |
NLEJ186202113 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ186202113</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707040545.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070506s1986 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ186202113</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ186202113</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Urinary enzyme analysis in renal allograft transplantation</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1986</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kotanko, P.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Keiler, R.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Knabl, L.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Aulitzky, W.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Margreiter, R.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gstraunthaler, G.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pfaller, W.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Clinica Chimica Acta</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">160(1986), 2, Seite 137-144</subfield><subfield code="w">(DE-627)NLEJ184917921</subfield><subfield code="w">(DE-600)1499920-1</subfield><subfield code="x">0009-8981</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:160</subfield><subfield code="g">year:1986</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:137-144</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90134-8</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">160</subfield><subfield code="j">1986</subfield><subfield code="e">2</subfield><subfield code="h">137-144</subfield></datafield></record></collection>
|
| series2 |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ184917921 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| collection |
NL |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
0009-8981 |
| topic_title |
Urinary enzyme analysis in renal allograft transplantation |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
p k pk r k rk l k lk w a wa r m rm g g gg w p wp |
| hierarchy_parent_title |
Clinica Chimica Acta |
| hierarchy_parent_id |
NLEJ184917921 |
| hierarchy_top_title |
Clinica Chimica Acta |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)NLEJ184917921 (DE-600)1499920-1 |
| title |
Urinary enzyme analysis in renal allograft transplantation |
| spellingShingle |
Urinary enzyme analysis in renal allograft transplantation |
| ctrlnum |
(DE-627)NLEJ186202113 (DE-599)GBVNLZ186202113 |
| title_full |
Urinary enzyme analysis in renal allograft transplantation |
| journal |
Clinica Chimica Acta |
| journalStr |
Clinica Chimica Acta |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
1986 |
| contenttype_str_mv |
zzz |
| container_start_page |
137 |
| container_volume |
160 |
| format_se |
Elektronische Aufsätze |
| title_sort |
urinary enzyme analysis in renal allograft transplantation |
| title_auth |
Urinary enzyme analysis in renal allograft transplantation |
| abstract |
The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model. |
| abstractGer |
The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model. |
| abstract_unstemmed |
The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model. |
| collection_details |
GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE |
| container_issue |
2 |
| title_short |
Urinary enzyme analysis in renal allograft transplantation |
| url |
http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90134-8 |
| remote_bool |
true |
| author2 |
Kotanko, P. Keiler, R. Knabl, L. Aulitzky, W. Margreiter, R. Gstraunthaler, G. Pfaller, W. |
| author2Str |
Kotanko, P. Keiler, R. Knabl, L. Aulitzky, W. Margreiter, R. Gstraunthaler, G. Pfaller, W. |
| ppnlink |
NLEJ184917921 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth oth oth oth |
| up_date |
2024-07-06T06:16:25.965Z |
| _version_ |
1803809284127981568 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ186202113</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707040545.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070506s1986 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ186202113</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ186202113</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Urinary enzyme analysis in renal allograft transplantation</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1986</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The urinary excretion of four enzymes (fructose-1, 6-bisphosphatase, glutathione S-transferase, N-acetyl-β-d-glucosaminidase and pyruvate kinase) was assayed daily in 59 patients following renal cadaveric allografting. 51 patients were given cyclosporin A (CyA group) as an immunosuppressive, 8 patients were treated conventionally with azathioprine and prednisolone (CON-group). Urinary enzyme output was evaluated by two different mathematical models. Model A follows single enzyme excretion, whereas model B also analyzes enzyme patterns. The best results were obtained by a combined analysis of all four enzymes with model B. In the CON-group the sensitivity was 1.00, the specificity 0.85, the predictive values of positive test 0.45 and all 12 graft rejections were diagnosed correctly. In the CyA group the sensitivity was 0.40, the specificity 0.99, the predictive value of positive test 0.33, and 6 out of 9 rejections were recognized. The evaluation of the single enzymes did not produce similarly good results with either model.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kotanko, P.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Keiler, R.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Knabl, L.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Aulitzky, W.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Margreiter, R.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gstraunthaler, G.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pfaller, W.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Clinica Chimica Acta</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">160(1986), 2, Seite 137-144</subfield><subfield code="w">(DE-627)NLEJ184917921</subfield><subfield code="w">(DE-600)1499920-1</subfield><subfield code="x">0009-8981</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:160</subfield><subfield code="g">year:1986</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:137-144</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90134-8</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">160</subfield><subfield code="j">1986</subfield><subfield code="e">2</subfield><subfield code="h">137-144</subfield></datafield></record></collection>
|
| score |
7.3995275 |