Marker chromosome 1q+ in acute lymphocytic leukemia
This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the c...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1987 |
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| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
|---|---|
| Übergeordnetes Werk: |
in: Cancer Genetics and Cytogenetics - Amsterdam : Elsevier, 24(1987), 2, Seite 251-255 |
| Übergeordnetes Werk: |
volume:24 ; year:1987 ; number:2 ; pages:251-255 |
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| 520 | |a This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the cells of the clone. Duplication was found in 30% of the metaphases, and in 15% triplication of the proximal segment of the long arm of chromosome #1 (q11-q21). In one metaphase the long arm of chromosome #1 is made up of segment q11-q21 four times repeated. Aberrations of chromosome #1 support the idea that heterochromatic region may be related to the higher degree of the cell malignity. | ||
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| 700 | 1 | |a Petkovic, I. |4 oth | |
| 700 | 1 | |a Nakic, M. |4 oth | |
| 700 | 1 | |a Tiefenbach, A. |4 oth | |
| 700 | 1 | |a Konja, J. |4 oth | |
| 700 | 1 | |a Kastelan, M. |4 oth | |
| 700 | 1 | |a Rajic, L. |4 oth | |
| 700 | 1 | |a Feminic-Kes, R. |4 oth | |
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(DE-627)NLEJ186654472 (DE-599)GBVNLZ186654472 DE-627 ger DE-627 rakwb eng Marker chromosome 1q+ in acute lymphocytic leukemia 1987 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the cells of the clone. Duplication was found in 30% of the metaphases, and in 15% triplication of the proximal segment of the long arm of chromosome #1 (q11-q21). In one metaphase the long arm of chromosome #1 is made up of segment q11-q21 four times repeated. Aberrations of chromosome #1 support the idea that heterochromatic region may be related to the higher degree of the cell malignity. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Petkovic, I. oth Nakic, M. oth Tiefenbach, A. oth Konja, J. oth Kastelan, M. oth Rajic, L. oth Feminic-Kes, R. oth in Cancer Genetics and Cytogenetics Amsterdam : Elsevier 24(1987), 2, Seite 251-255 (DE-627)NLEJ186641591 (DE-600)2004205-X 0165-4608 nnns volume:24 year:1987 number:2 pages:251-255 http://linkinghub.elsevier.com/retrieve/pii/0165-4608(87)90106-3 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 24 1987 2 251-255 |
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(DE-627)NLEJ186654472 (DE-599)GBVNLZ186654472 DE-627 ger DE-627 rakwb eng Marker chromosome 1q+ in acute lymphocytic leukemia 1987 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the cells of the clone. Duplication was found in 30% of the metaphases, and in 15% triplication of the proximal segment of the long arm of chromosome #1 (q11-q21). In one metaphase the long arm of chromosome #1 is made up of segment q11-q21 four times repeated. Aberrations of chromosome #1 support the idea that heterochromatic region may be related to the higher degree of the cell malignity. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Petkovic, I. oth Nakic, M. oth Tiefenbach, A. oth Konja, J. oth Kastelan, M. oth Rajic, L. oth Feminic-Kes, R. oth in Cancer Genetics and Cytogenetics Amsterdam : Elsevier 24(1987), 2, Seite 251-255 (DE-627)NLEJ186641591 (DE-600)2004205-X 0165-4608 nnns volume:24 year:1987 number:2 pages:251-255 http://linkinghub.elsevier.com/retrieve/pii/0165-4608(87)90106-3 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 24 1987 2 251-255 |
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(DE-627)NLEJ186654472 (DE-599)GBVNLZ186654472 DE-627 ger DE-627 rakwb eng Marker chromosome 1q+ in acute lymphocytic leukemia 1987 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the cells of the clone. Duplication was found in 30% of the metaphases, and in 15% triplication of the proximal segment of the long arm of chromosome #1 (q11-q21). In one metaphase the long arm of chromosome #1 is made up of segment q11-q21 four times repeated. Aberrations of chromosome #1 support the idea that heterochromatic region may be related to the higher degree of the cell malignity. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Petkovic, I. oth Nakic, M. oth Tiefenbach, A. oth Konja, J. oth Kastelan, M. oth Rajic, L. oth Feminic-Kes, R. oth in Cancer Genetics and Cytogenetics Amsterdam : Elsevier 24(1987), 2, Seite 251-255 (DE-627)NLEJ186641591 (DE-600)2004205-X 0165-4608 nnns volume:24 year:1987 number:2 pages:251-255 http://linkinghub.elsevier.com/retrieve/pii/0165-4608(87)90106-3 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 24 1987 2 251-255 |
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(DE-627)NLEJ186654472 (DE-599)GBVNLZ186654472 DE-627 ger DE-627 rakwb eng Marker chromosome 1q+ in acute lymphocytic leukemia 1987 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the cells of the clone. Duplication was found in 30% of the metaphases, and in 15% triplication of the proximal segment of the long arm of chromosome #1 (q11-q21). In one metaphase the long arm of chromosome #1 is made up of segment q11-q21 four times repeated. Aberrations of chromosome #1 support the idea that heterochromatic region may be related to the higher degree of the cell malignity. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Petkovic, I. oth Nakic, M. oth Tiefenbach, A. oth Konja, J. oth Kastelan, M. oth Rajic, L. oth Feminic-Kes, R. oth in Cancer Genetics and Cytogenetics Amsterdam : Elsevier 24(1987), 2, Seite 251-255 (DE-627)NLEJ186641591 (DE-600)2004205-X 0165-4608 nnns volume:24 year:1987 number:2 pages:251-255 http://linkinghub.elsevier.com/retrieve/pii/0165-4608(87)90106-3 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 24 1987 2 251-255 |
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(DE-627)NLEJ186654472 (DE-599)GBVNLZ186654472 DE-627 ger DE-627 rakwb eng Marker chromosome 1q+ in acute lymphocytic leukemia 1987 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the cells of the clone. Duplication was found in 30% of the metaphases, and in 15% triplication of the proximal segment of the long arm of chromosome #1 (q11-q21). In one metaphase the long arm of chromosome #1 is made up of segment q11-q21 four times repeated. Aberrations of chromosome #1 support the idea that heterochromatic region may be related to the higher degree of the cell malignity. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Petkovic, I. oth Nakic, M. oth Tiefenbach, A. oth Konja, J. oth Kastelan, M. oth Rajic, L. oth Feminic-Kes, R. oth in Cancer Genetics and Cytogenetics Amsterdam : Elsevier 24(1987), 2, Seite 251-255 (DE-627)NLEJ186641591 (DE-600)2004205-X 0165-4608 nnns volume:24 year:1987 number:2 pages:251-255 http://linkinghub.elsevier.com/retrieve/pii/0165-4608(87)90106-3 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 24 1987 2 251-255 |
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This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the cells of the clone. Duplication was found in 30% of the metaphases, and in 15% triplication of the proximal segment of the long arm of chromosome #1 (q11-q21). In one metaphase the long arm of chromosome #1 is made up of segment q11-q21 four times repeated. Aberrations of chromosome #1 support the idea that heterochromatic region may be related to the higher degree of the cell malignity. |
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This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the cells of the clone. Duplication was found in 30% of the metaphases, and in 15% triplication of the proximal segment of the long arm of chromosome #1 (q11-q21). In one metaphase the long arm of chromosome #1 is made up of segment q11-q21 four times repeated. Aberrations of chromosome #1 support the idea that heterochromatic region may be related to the higher degree of the cell malignity. |
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This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the cells of the clone. Duplication was found in 30% of the metaphases, and in 15% triplication of the proximal segment of the long arm of chromosome #1 (q11-q21). In one metaphase the long arm of chromosome #1 is made up of segment q11-q21 four times repeated. Aberrations of chromosome #1 support the idea that heterochromatic region may be related to the higher degree of the cell malignity. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ186654472</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707053917.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070506s1987 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ186654472</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ186654472</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Marker chromosome 1q+ in acute lymphocytic leukemia</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1987</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">This paper presents the results of a cytogenetic analysis on a patient with acute lymphocytic leukemia (ALL) type L2 according to the FAB classification. Of the metaphases examined, 69.3% belong to the aberrant clone of pseudodiploid karyotype. Marker chromosome 14q+ has been identified in all the cells of the clone. Duplication was found in 30% of the metaphases, and in 15% triplication of the proximal segment of the long arm of chromosome #1 (q11-q21). In one metaphase the long arm of chromosome #1 is made up of segment q11-q21 four times repeated. Aberrations of chromosome #1 support the idea that heterochromatic region may be related to the higher degree of the cell malignity.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Petkovic, I.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nakic, M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tiefenbach, A.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Konja, J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kastelan, M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rajic, L.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Feminic-Kes, R.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Cancer Genetics and Cytogenetics</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">24(1987), 2, Seite 251-255</subfield><subfield code="w">(DE-627)NLEJ186641591</subfield><subfield code="w">(DE-600)2004205-X</subfield><subfield code="x">0165-4608</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:24</subfield><subfield code="g">year:1987</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:251-255</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://linkinghub.elsevier.com/retrieve/pii/0165-4608(87)90106-3</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">24</subfield><subfield code="j">1987</subfield><subfield code="e">2</subfield><subfield code="h">251-255</subfield></datafield></record></collection>
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