Characterization of β-endorphin peptides in the spinal cord of the rat
The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentrat...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1989 |
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| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
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| Übergeordnetes Werk: |
in: Peptides - Amsterdam : Elsevier, 10(1989), 5, Seite 1049-1054 |
| Übergeordnetes Werk: |
volume:10 ; year:1989 ; number:5 ; pages:1049-1054 |
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NLEJ187007411 |
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| 245 | 1 | 0 | |a Characterization of β-endorphin peptides in the spinal cord of the rat |
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| 520 | |a The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentration of β-EPLIR expressed as pg per mg tissue was similar in the four regions of the spinal cord. Sephadex G-75 chromatography demonstrated the presence, in all four regions of the spinal cord, of β-endorphin (β-EP) immunoreactive peptides eluting at the positions of standard β-EP and β-lipotropin (β-LPH) peptides as well as a high molecular weight form eluting prior to β-LPH. High performance liquid chromatography of the β-EP-sized peptides indicated some differences in the relative proportions of the various β-EP-sized peptides among the four regions of the spinal cord, which suggest a different origin of the β-EP fibers terminating in different regions of the spinal cord as well as different physiological importance of the β-endorphin peptides in the various spinal cord regions. | ||
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(DE-627)NLEJ187007411 (DE-599)GBVNLZ187007411 DE-627 ger DE-627 rakwb eng Characterization of β-endorphin peptides in the spinal cord of the rat 1989 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentration of β-EPLIR expressed as pg per mg tissue was similar in the four regions of the spinal cord. Sephadex G-75 chromatography demonstrated the presence, in all four regions of the spinal cord, of β-endorphin (β-EP) immunoreactive peptides eluting at the positions of standard β-EP and β-lipotropin (β-LPH) peptides as well as a high molecular weight form eluting prior to β-LPH. High performance liquid chromatography of the β-EP-sized peptides indicated some differences in the relative proportions of the various β-EP-sized peptides among the four regions of the spinal cord, which suggest a different origin of the β-EP fibers terminating in different regions of the spinal cord as well as different physiological importance of the β-endorphin peptides in the various spinal cord regions. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Gianoulakis, C. oth Angelogianni, P. oth in Peptides Amsterdam : Elsevier 10(1989), 5, Seite 1049-1054 (DE-627)NLEJ177279168 (DE-600)2019194-7 0196-9781 nnns volume:10 year:1989 number:5 pages:1049-1054 http://linkinghub.elsevier.com/retrieve/pii/0196-9781(89)90189-7 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 10 1989 5 1049-1054 |
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(DE-627)NLEJ187007411 (DE-599)GBVNLZ187007411 DE-627 ger DE-627 rakwb eng Characterization of β-endorphin peptides in the spinal cord of the rat 1989 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentration of β-EPLIR expressed as pg per mg tissue was similar in the four regions of the spinal cord. Sephadex G-75 chromatography demonstrated the presence, in all four regions of the spinal cord, of β-endorphin (β-EP) immunoreactive peptides eluting at the positions of standard β-EP and β-lipotropin (β-LPH) peptides as well as a high molecular weight form eluting prior to β-LPH. High performance liquid chromatography of the β-EP-sized peptides indicated some differences in the relative proportions of the various β-EP-sized peptides among the four regions of the spinal cord, which suggest a different origin of the β-EP fibers terminating in different regions of the spinal cord as well as different physiological importance of the β-endorphin peptides in the various spinal cord regions. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Gianoulakis, C. oth Angelogianni, P. oth in Peptides Amsterdam : Elsevier 10(1989), 5, Seite 1049-1054 (DE-627)NLEJ177279168 (DE-600)2019194-7 0196-9781 nnns volume:10 year:1989 number:5 pages:1049-1054 http://linkinghub.elsevier.com/retrieve/pii/0196-9781(89)90189-7 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 10 1989 5 1049-1054 |
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(DE-627)NLEJ187007411 (DE-599)GBVNLZ187007411 DE-627 ger DE-627 rakwb eng Characterization of β-endorphin peptides in the spinal cord of the rat 1989 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentration of β-EPLIR expressed as pg per mg tissue was similar in the four regions of the spinal cord. Sephadex G-75 chromatography demonstrated the presence, in all four regions of the spinal cord, of β-endorphin (β-EP) immunoreactive peptides eluting at the positions of standard β-EP and β-lipotropin (β-LPH) peptides as well as a high molecular weight form eluting prior to β-LPH. High performance liquid chromatography of the β-EP-sized peptides indicated some differences in the relative proportions of the various β-EP-sized peptides among the four regions of the spinal cord, which suggest a different origin of the β-EP fibers terminating in different regions of the spinal cord as well as different physiological importance of the β-endorphin peptides in the various spinal cord regions. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Gianoulakis, C. oth Angelogianni, P. oth in Peptides Amsterdam : Elsevier 10(1989), 5, Seite 1049-1054 (DE-627)NLEJ177279168 (DE-600)2019194-7 0196-9781 nnns volume:10 year:1989 number:5 pages:1049-1054 http://linkinghub.elsevier.com/retrieve/pii/0196-9781(89)90189-7 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 10 1989 5 1049-1054 |
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(DE-627)NLEJ187007411 (DE-599)GBVNLZ187007411 DE-627 ger DE-627 rakwb eng Characterization of β-endorphin peptides in the spinal cord of the rat 1989 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentration of β-EPLIR expressed as pg per mg tissue was similar in the four regions of the spinal cord. Sephadex G-75 chromatography demonstrated the presence, in all four regions of the spinal cord, of β-endorphin (β-EP) immunoreactive peptides eluting at the positions of standard β-EP and β-lipotropin (β-LPH) peptides as well as a high molecular weight form eluting prior to β-LPH. High performance liquid chromatography of the β-EP-sized peptides indicated some differences in the relative proportions of the various β-EP-sized peptides among the four regions of the spinal cord, which suggest a different origin of the β-EP fibers terminating in different regions of the spinal cord as well as different physiological importance of the β-endorphin peptides in the various spinal cord regions. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Gianoulakis, C. oth Angelogianni, P. oth in Peptides Amsterdam : Elsevier 10(1989), 5, Seite 1049-1054 (DE-627)NLEJ177279168 (DE-600)2019194-7 0196-9781 nnns volume:10 year:1989 number:5 pages:1049-1054 http://linkinghub.elsevier.com/retrieve/pii/0196-9781(89)90189-7 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 10 1989 5 1049-1054 |
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(DE-627)NLEJ187007411 (DE-599)GBVNLZ187007411 DE-627 ger DE-627 rakwb eng Characterization of β-endorphin peptides in the spinal cord of the rat 1989 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentration of β-EPLIR expressed as pg per mg tissue was similar in the four regions of the spinal cord. Sephadex G-75 chromatography demonstrated the presence, in all four regions of the spinal cord, of β-endorphin (β-EP) immunoreactive peptides eluting at the positions of standard β-EP and β-lipotropin (β-LPH) peptides as well as a high molecular weight form eluting prior to β-LPH. High performance liquid chromatography of the β-EP-sized peptides indicated some differences in the relative proportions of the various β-EP-sized peptides among the four regions of the spinal cord, which suggest a different origin of the β-EP fibers terminating in different regions of the spinal cord as well as different physiological importance of the β-endorphin peptides in the various spinal cord regions. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Gianoulakis, C. oth Angelogianni, P. oth in Peptides Amsterdam : Elsevier 10(1989), 5, Seite 1049-1054 (DE-627)NLEJ177279168 (DE-600)2019194-7 0196-9781 nnns volume:10 year:1989 number:5 pages:1049-1054 http://linkinghub.elsevier.com/retrieve/pii/0196-9781(89)90189-7 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 10 1989 5 1049-1054 |
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Characterization of β-endorphin peptides in the spinal cord of the rat |
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The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentration of β-EPLIR expressed as pg per mg tissue was similar in the four regions of the spinal cord. Sephadex G-75 chromatography demonstrated the presence, in all four regions of the spinal cord, of β-endorphin (β-EP) immunoreactive peptides eluting at the positions of standard β-EP and β-lipotropin (β-LPH) peptides as well as a high molecular weight form eluting prior to β-LPH. High performance liquid chromatography of the β-EP-sized peptides indicated some differences in the relative proportions of the various β-EP-sized peptides among the four regions of the spinal cord, which suggest a different origin of the β-EP fibers terminating in different regions of the spinal cord as well as different physiological importance of the β-endorphin peptides in the various spinal cord regions. |
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The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentration of β-EPLIR expressed as pg per mg tissue was similar in the four regions of the spinal cord. Sephadex G-75 chromatography demonstrated the presence, in all four regions of the spinal cord, of β-endorphin (β-EP) immunoreactive peptides eluting at the positions of standard β-EP and β-lipotropin (β-LPH) peptides as well as a high molecular weight form eluting prior to β-LPH. High performance liquid chromatography of the β-EP-sized peptides indicated some differences in the relative proportions of the various β-EP-sized peptides among the four regions of the spinal cord, which suggest a different origin of the β-EP fibers terminating in different regions of the spinal cord as well as different physiological importance of the β-endorphin peptides in the various spinal cord regions. |
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The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentration of β-EPLIR expressed as pg per mg tissue was similar in the four regions of the spinal cord. Sephadex G-75 chromatography demonstrated the presence, in all four regions of the spinal cord, of β-endorphin (β-EP) immunoreactive peptides eluting at the positions of standard β-EP and β-lipotropin (β-LPH) peptides as well as a high molecular weight form eluting prior to β-LPH. High performance liquid chromatography of the β-EP-sized peptides indicated some differences in the relative proportions of the various β-EP-sized peptides among the four regions of the spinal cord, which suggest a different origin of the β-EP fibers terminating in different regions of the spinal cord as well as different physiological importance of the β-endorphin peptides in the various spinal cord regions. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ187007411</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707063902.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070506s1989 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ187007411</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ187007411</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Characterization of β-endorphin peptides in the spinal cord of the rat</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1989</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The objective of the present studies was to estimate the total content of β-endorphin-like immunoreactivity (β-EPLIR) and to characterize the β-endorphin-like peptides in distinct regions of the spinal cord using gel filtration and reverse phase high performance liquid chromatography. The concentration of β-EPLIR expressed as pg per mg tissue was similar in the four regions of the spinal cord. Sephadex G-75 chromatography demonstrated the presence, in all four regions of the spinal cord, of β-endorphin (β-EP) immunoreactive peptides eluting at the positions of standard β-EP and β-lipotropin (β-LPH) peptides as well as a high molecular weight form eluting prior to β-LPH. High performance liquid chromatography of the β-EP-sized peptides indicated some differences in the relative proportions of the various β-EP-sized peptides among the four regions of the spinal cord, which suggest a different origin of the β-EP fibers terminating in different regions of the spinal cord as well as different physiological importance of the β-endorphin peptides in the various spinal cord regions.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gianoulakis, C.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Angelogianni, P.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Peptides</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">10(1989), 5, Seite 1049-1054</subfield><subfield code="w">(DE-627)NLEJ177279168</subfield><subfield code="w">(DE-600)2019194-7</subfield><subfield code="x">0196-9781</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:10</subfield><subfield code="g">year:1989</subfield><subfield code="g">number:5</subfield><subfield code="g">pages:1049-1054</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://linkinghub.elsevier.com/retrieve/pii/0196-9781(89)90189-7</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">10</subfield><subfield code="j">1989</subfield><subfield code="e">5</subfield><subfield code="h">1049-1054</subfield></datafield></record></collection>
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