Behavioral responses elicited by intraperitoneal neurotensin in guinea pigs
The potential behavioral responses to single intraperitoneal (IP) injection of neurotensin (NT) were examined in conscious, freely moving guinea pigs. Most animals injected with NT solvent (i.e., controls) or NT solution with low NT concentration (i.e., 5.4 nM) exhibited little or no particular beha...
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| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1992 |
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| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
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| Übergeordnetes Werk: |
in: Peptides - Amsterdam : Elsevier, 13(1992), 4, Seite 841-842 |
| Übergeordnetes Werk: |
volume:13 ; year:1992 ; number:4 ; pages:841-842 |
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| 520 | |a The potential behavioral responses to single intraperitoneal (IP) injection of neurotensin (NT) were examined in conscious, freely moving guinea pigs. Most animals injected with NT solvent (i.e., controls) or NT solution with low NT concentration (i.e., 5.4 nM) exhibited little or no particular behavioral reaction. On the other hand, 50 to 75% of the animals given IP injection of NT with 54, 540, or 5400 nM of NT exhibited motor responses characterized by a transient episode of clonic body jerks. Vocalization responses were observed in less than 25% of the animals given IP NT. Animal pretreatment with morphine reduced the incidence of motor and vocalization responses. The results were interpreted as an indication that IP injection of moderately concentrated NT solution (i.e., =<54 nM) is probably a weak noxious stimulus in conscious guinea pigs. | ||
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(DE-627)NLEJ187016038 (DE-599)GBVNLZ187016038 DE-627 ger DE-627 rakwb eng Behavioral responses elicited by intraperitoneal neurotensin in guinea pigs 1992 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The potential behavioral responses to single intraperitoneal (IP) injection of neurotensin (NT) were examined in conscious, freely moving guinea pigs. Most animals injected with NT solvent (i.e., controls) or NT solution with low NT concentration (i.e., 5.4 nM) exhibited little or no particular behavioral reaction. On the other hand, 50 to 75% of the animals given IP injection of NT with 54, 540, or 5400 nM of NT exhibited motor responses characterized by a transient episode of clonic body jerks. Vocalization responses were observed in less than 25% of the animals given IP NT. Animal pretreatment with morphine reduced the incidence of motor and vocalization responses. The results were interpreted as an indication that IP injection of moderately concentrated NT solution (i.e., =<54 nM) is probably a weak noxious stimulus in conscious guinea pigs. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Rioux, F. oth Lemieux, M. oth in Peptides Amsterdam : Elsevier 13(1992), 4, Seite 841-842 (DE-627)NLEJ177279168 (DE-600)2019194-7 0196-9781 nnns volume:13 year:1992 number:4 pages:841-842 http://linkinghub.elsevier.com/retrieve/pii/0196-9781(92)90194-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 13 1992 4 841-842 |
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(DE-627)NLEJ187016038 (DE-599)GBVNLZ187016038 DE-627 ger DE-627 rakwb eng Behavioral responses elicited by intraperitoneal neurotensin in guinea pigs 1992 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The potential behavioral responses to single intraperitoneal (IP) injection of neurotensin (NT) were examined in conscious, freely moving guinea pigs. Most animals injected with NT solvent (i.e., controls) or NT solution with low NT concentration (i.e., 5.4 nM) exhibited little or no particular behavioral reaction. On the other hand, 50 to 75% of the animals given IP injection of NT with 54, 540, or 5400 nM of NT exhibited motor responses characterized by a transient episode of clonic body jerks. Vocalization responses were observed in less than 25% of the animals given IP NT. Animal pretreatment with morphine reduced the incidence of motor and vocalization responses. The results were interpreted as an indication that IP injection of moderately concentrated NT solution (i.e., =<54 nM) is probably a weak noxious stimulus in conscious guinea pigs. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Rioux, F. oth Lemieux, M. oth in Peptides Amsterdam : Elsevier 13(1992), 4, Seite 841-842 (DE-627)NLEJ177279168 (DE-600)2019194-7 0196-9781 nnns volume:13 year:1992 number:4 pages:841-842 http://linkinghub.elsevier.com/retrieve/pii/0196-9781(92)90194-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 13 1992 4 841-842 |
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(DE-627)NLEJ187016038 (DE-599)GBVNLZ187016038 DE-627 ger DE-627 rakwb eng Behavioral responses elicited by intraperitoneal neurotensin in guinea pigs 1992 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The potential behavioral responses to single intraperitoneal (IP) injection of neurotensin (NT) were examined in conscious, freely moving guinea pigs. Most animals injected with NT solvent (i.e., controls) or NT solution with low NT concentration (i.e., 5.4 nM) exhibited little or no particular behavioral reaction. On the other hand, 50 to 75% of the animals given IP injection of NT with 54, 540, or 5400 nM of NT exhibited motor responses characterized by a transient episode of clonic body jerks. Vocalization responses were observed in less than 25% of the animals given IP NT. Animal pretreatment with morphine reduced the incidence of motor and vocalization responses. The results were interpreted as an indication that IP injection of moderately concentrated NT solution (i.e., =<54 nM) is probably a weak noxious stimulus in conscious guinea pigs. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Rioux, F. oth Lemieux, M. oth in Peptides Amsterdam : Elsevier 13(1992), 4, Seite 841-842 (DE-627)NLEJ177279168 (DE-600)2019194-7 0196-9781 nnns volume:13 year:1992 number:4 pages:841-842 http://linkinghub.elsevier.com/retrieve/pii/0196-9781(92)90194-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 13 1992 4 841-842 |
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(DE-627)NLEJ187016038 (DE-599)GBVNLZ187016038 DE-627 ger DE-627 rakwb eng Behavioral responses elicited by intraperitoneal neurotensin in guinea pigs 1992 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The potential behavioral responses to single intraperitoneal (IP) injection of neurotensin (NT) were examined in conscious, freely moving guinea pigs. Most animals injected with NT solvent (i.e., controls) or NT solution with low NT concentration (i.e., 5.4 nM) exhibited little or no particular behavioral reaction. On the other hand, 50 to 75% of the animals given IP injection of NT with 54, 540, or 5400 nM of NT exhibited motor responses characterized by a transient episode of clonic body jerks. Vocalization responses were observed in less than 25% of the animals given IP NT. Animal pretreatment with morphine reduced the incidence of motor and vocalization responses. The results were interpreted as an indication that IP injection of moderately concentrated NT solution (i.e., =<54 nM) is probably a weak noxious stimulus in conscious guinea pigs. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Rioux, F. oth Lemieux, M. oth in Peptides Amsterdam : Elsevier 13(1992), 4, Seite 841-842 (DE-627)NLEJ177279168 (DE-600)2019194-7 0196-9781 nnns volume:13 year:1992 number:4 pages:841-842 http://linkinghub.elsevier.com/retrieve/pii/0196-9781(92)90194-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 13 1992 4 841-842 |
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(DE-627)NLEJ187016038 (DE-599)GBVNLZ187016038 DE-627 ger DE-627 rakwb eng Behavioral responses elicited by intraperitoneal neurotensin in guinea pigs 1992 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The potential behavioral responses to single intraperitoneal (IP) injection of neurotensin (NT) were examined in conscious, freely moving guinea pigs. Most animals injected with NT solvent (i.e., controls) or NT solution with low NT concentration (i.e., 5.4 nM) exhibited little or no particular behavioral reaction. On the other hand, 50 to 75% of the animals given IP injection of NT with 54, 540, or 5400 nM of NT exhibited motor responses characterized by a transient episode of clonic body jerks. Vocalization responses were observed in less than 25% of the animals given IP NT. Animal pretreatment with morphine reduced the incidence of motor and vocalization responses. The results were interpreted as an indication that IP injection of moderately concentrated NT solution (i.e., =<54 nM) is probably a weak noxious stimulus in conscious guinea pigs. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Rioux, F. oth Lemieux, M. oth in Peptides Amsterdam : Elsevier 13(1992), 4, Seite 841-842 (DE-627)NLEJ177279168 (DE-600)2019194-7 0196-9781 nnns volume:13 year:1992 number:4 pages:841-842 http://linkinghub.elsevier.com/retrieve/pii/0196-9781(92)90194-8 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 13 1992 4 841-842 |
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The potential behavioral responses to single intraperitoneal (IP) injection of neurotensin (NT) were examined in conscious, freely moving guinea pigs. Most animals injected with NT solvent (i.e., controls) or NT solution with low NT concentration (i.e., 5.4 nM) exhibited little or no particular behavioral reaction. On the other hand, 50 to 75% of the animals given IP injection of NT with 54, 540, or 5400 nM of NT exhibited motor responses characterized by a transient episode of clonic body jerks. Vocalization responses were observed in less than 25% of the animals given IP NT. Animal pretreatment with morphine reduced the incidence of motor and vocalization responses. The results were interpreted as an indication that IP injection of moderately concentrated NT solution (i.e., =<54 nM) is probably a weak noxious stimulus in conscious guinea pigs. |
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The potential behavioral responses to single intraperitoneal (IP) injection of neurotensin (NT) were examined in conscious, freely moving guinea pigs. Most animals injected with NT solvent (i.e., controls) or NT solution with low NT concentration (i.e., 5.4 nM) exhibited little or no particular behavioral reaction. On the other hand, 50 to 75% of the animals given IP injection of NT with 54, 540, or 5400 nM of NT exhibited motor responses characterized by a transient episode of clonic body jerks. Vocalization responses were observed in less than 25% of the animals given IP NT. Animal pretreatment with morphine reduced the incidence of motor and vocalization responses. The results were interpreted as an indication that IP injection of moderately concentrated NT solution (i.e., =<54 nM) is probably a weak noxious stimulus in conscious guinea pigs. |
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The potential behavioral responses to single intraperitoneal (IP) injection of neurotensin (NT) were examined in conscious, freely moving guinea pigs. Most animals injected with NT solvent (i.e., controls) or NT solution with low NT concentration (i.e., 5.4 nM) exhibited little or no particular behavioral reaction. On the other hand, 50 to 75% of the animals given IP injection of NT with 54, 540, or 5400 nM of NT exhibited motor responses characterized by a transient episode of clonic body jerks. Vocalization responses were observed in less than 25% of the animals given IP NT. Animal pretreatment with morphine reduced the incidence of motor and vocalization responses. The results were interpreted as an indication that IP injection of moderately concentrated NT solution (i.e., =<54 nM) is probably a weak noxious stimulus in conscious guinea pigs. |
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