Structure and activity of the translocated c-myc in mouse plasmacytoma XRPC-24
In the mouse plasmacytoma XRPC-24 both c-mos and c-myc are rearranged. We cloned the rearranged c-myc and found that it was translocated to the immunoglobulin C"α locus. The breakpoint is at the end of exon 1 in c-myc and approximately 0.5 kb upstream from exon 1 of C"α. The cloned translo...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
1986 |
|---|
| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
|---|---|
| Übergeordnetes Werk: |
in: Gene - Amsterdam : Elsevier, 48(1986), 2-3, Seite 297-300 |
| Übergeordnetes Werk: |
volume:48 ; year:1986 ; number:2-3 ; pages:297-300 |
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| 520 | |a In the mouse plasmacytoma XRPC-24 both c-mos and c-myc are rearranged. We cloned the rearranged c-myc and found that it was translocated to the immunoglobulin C"α locus. The breakpoint is at the end of exon 1 in c-myc and approximately 0.5 kb upstream from exon 1 of C"α. The cloned translocated c-myc linked to a strong transcriptional promoter can efficiently transform rat embryo fibroblasts when co-transfected with the activated Ha-ras. The transformed cells are tumorigenic in syngeneic rats. | ||
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(DE-627)NLEJ187337594 (DE-599)GBVNLZ187337594 DE-627 ger DE-627 rakwb eng Structure and activity of the translocated c-myc in mouse plasmacytoma XRPC-24 1986 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In the mouse plasmacytoma XRPC-24 both c-mos and c-myc are rearranged. We cloned the rearranged c-myc and found that it was translocated to the immunoglobulin C"α locus. The breakpoint is at the end of exon 1 in c-myc and approximately 0.5 kb upstream from exon 1 of C"α. The cloned translocated c-myc linked to a strong transcriptional promoter can efficiently transform rat embryo fibroblasts when co-transfected with the activated Ha-ras. The transformed cells are tumorigenic in syngeneic rats. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Moav, B. oth Horowitz, M. oth Cohen, J.B. oth Rechavi, G. oth Eliyahu, E. oth Oren, M. oth Givol, D. oth in Gene Amsterdam : Elsevier 48(1986), 2-3, Seite 297-300 (DE-627)NLEJ177212578 (DE-600)1491012-3 0378-1119 nnns volume:48 year:1986 number:2-3 pages:297-300 http://linkinghub.elsevier.com/retrieve/pii/0378-1119(86)90089-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 48 1986 2-3 297-300 |
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(DE-627)NLEJ187337594 (DE-599)GBVNLZ187337594 DE-627 ger DE-627 rakwb eng Structure and activity of the translocated c-myc in mouse plasmacytoma XRPC-24 1986 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In the mouse plasmacytoma XRPC-24 both c-mos and c-myc are rearranged. We cloned the rearranged c-myc and found that it was translocated to the immunoglobulin C"α locus. The breakpoint is at the end of exon 1 in c-myc and approximately 0.5 kb upstream from exon 1 of C"α. The cloned translocated c-myc linked to a strong transcriptional promoter can efficiently transform rat embryo fibroblasts when co-transfected with the activated Ha-ras. The transformed cells are tumorigenic in syngeneic rats. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Moav, B. oth Horowitz, M. oth Cohen, J.B. oth Rechavi, G. oth Eliyahu, E. oth Oren, M. oth Givol, D. oth in Gene Amsterdam : Elsevier 48(1986), 2-3, Seite 297-300 (DE-627)NLEJ177212578 (DE-600)1491012-3 0378-1119 nnns volume:48 year:1986 number:2-3 pages:297-300 http://linkinghub.elsevier.com/retrieve/pii/0378-1119(86)90089-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 48 1986 2-3 297-300 |
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(DE-627)NLEJ187337594 (DE-599)GBVNLZ187337594 DE-627 ger DE-627 rakwb eng Structure and activity of the translocated c-myc in mouse plasmacytoma XRPC-24 1986 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In the mouse plasmacytoma XRPC-24 both c-mos and c-myc are rearranged. We cloned the rearranged c-myc and found that it was translocated to the immunoglobulin C"α locus. The breakpoint is at the end of exon 1 in c-myc and approximately 0.5 kb upstream from exon 1 of C"α. The cloned translocated c-myc linked to a strong transcriptional promoter can efficiently transform rat embryo fibroblasts when co-transfected with the activated Ha-ras. The transformed cells are tumorigenic in syngeneic rats. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Moav, B. oth Horowitz, M. oth Cohen, J.B. oth Rechavi, G. oth Eliyahu, E. oth Oren, M. oth Givol, D. oth in Gene Amsterdam : Elsevier 48(1986), 2-3, Seite 297-300 (DE-627)NLEJ177212578 (DE-600)1491012-3 0378-1119 nnns volume:48 year:1986 number:2-3 pages:297-300 http://linkinghub.elsevier.com/retrieve/pii/0378-1119(86)90089-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 48 1986 2-3 297-300 |
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(DE-627)NLEJ187337594 (DE-599)GBVNLZ187337594 DE-627 ger DE-627 rakwb eng Structure and activity of the translocated c-myc in mouse plasmacytoma XRPC-24 1986 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In the mouse plasmacytoma XRPC-24 both c-mos and c-myc are rearranged. We cloned the rearranged c-myc and found that it was translocated to the immunoglobulin C"α locus. The breakpoint is at the end of exon 1 in c-myc and approximately 0.5 kb upstream from exon 1 of C"α. The cloned translocated c-myc linked to a strong transcriptional promoter can efficiently transform rat embryo fibroblasts when co-transfected with the activated Ha-ras. The transformed cells are tumorigenic in syngeneic rats. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Moav, B. oth Horowitz, M. oth Cohen, J.B. oth Rechavi, G. oth Eliyahu, E. oth Oren, M. oth Givol, D. oth in Gene Amsterdam : Elsevier 48(1986), 2-3, Seite 297-300 (DE-627)NLEJ177212578 (DE-600)1491012-3 0378-1119 nnns volume:48 year:1986 number:2-3 pages:297-300 http://linkinghub.elsevier.com/retrieve/pii/0378-1119(86)90089-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 48 1986 2-3 297-300 |
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(DE-627)NLEJ187337594 (DE-599)GBVNLZ187337594 DE-627 ger DE-627 rakwb eng Structure and activity of the translocated c-myc in mouse plasmacytoma XRPC-24 1986 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In the mouse plasmacytoma XRPC-24 both c-mos and c-myc are rearranged. We cloned the rearranged c-myc and found that it was translocated to the immunoglobulin C"α locus. The breakpoint is at the end of exon 1 in c-myc and approximately 0.5 kb upstream from exon 1 of C"α. The cloned translocated c-myc linked to a strong transcriptional promoter can efficiently transform rat embryo fibroblasts when co-transfected with the activated Ha-ras. The transformed cells are tumorigenic in syngeneic rats. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Moav, B. oth Horowitz, M. oth Cohen, J.B. oth Rechavi, G. oth Eliyahu, E. oth Oren, M. oth Givol, D. oth in Gene Amsterdam : Elsevier 48(1986), 2-3, Seite 297-300 (DE-627)NLEJ177212578 (DE-600)1491012-3 0378-1119 nnns volume:48 year:1986 number:2-3 pages:297-300 http://linkinghub.elsevier.com/retrieve/pii/0378-1119(86)90089-2 GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 48 1986 2-3 297-300 |
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structure and activity of the translocated c-myc in mouse plasmacytoma xrpc-24 |
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Structure and activity of the translocated c-myc in mouse plasmacytoma XRPC-24 |
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In the mouse plasmacytoma XRPC-24 both c-mos and c-myc are rearranged. We cloned the rearranged c-myc and found that it was translocated to the immunoglobulin C"α locus. The breakpoint is at the end of exon 1 in c-myc and approximately 0.5 kb upstream from exon 1 of C"α. The cloned translocated c-myc linked to a strong transcriptional promoter can efficiently transform rat embryo fibroblasts when co-transfected with the activated Ha-ras. The transformed cells are tumorigenic in syngeneic rats. |
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In the mouse plasmacytoma XRPC-24 both c-mos and c-myc are rearranged. We cloned the rearranged c-myc and found that it was translocated to the immunoglobulin C"α locus. The breakpoint is at the end of exon 1 in c-myc and approximately 0.5 kb upstream from exon 1 of C"α. The cloned translocated c-myc linked to a strong transcriptional promoter can efficiently transform rat embryo fibroblasts when co-transfected with the activated Ha-ras. The transformed cells are tumorigenic in syngeneic rats. |
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In the mouse plasmacytoma XRPC-24 both c-mos and c-myc are rearranged. We cloned the rearranged c-myc and found that it was translocated to the immunoglobulin C"α locus. The breakpoint is at the end of exon 1 in c-myc and approximately 0.5 kb upstream from exon 1 of C"α. The cloned translocated c-myc linked to a strong transcriptional promoter can efficiently transform rat embryo fibroblasts when co-transfected with the activated Ha-ras. The transformed cells are tumorigenic in syngeneic rats. |
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Structure and activity of the translocated c-myc in mouse plasmacytoma XRPC-24 |
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