Synthesis, characterisation and high-performance liquid chromatography of C"6C"1"6 dicarboxylyl-mono-coenzyme A and -mono-carnitine esters
The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase hi...
Ausführliche Beschreibung
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Englisch |
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1991 |
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Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
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Übergeordnetes Werk: |
in: Journal of Chromatography B: Biomedical Sciences and Applications - Amsterdam : Elsevier, 570(1991), 2, Seite 253-276 |
Übergeordnetes Werk: |
volume:570 ; year:1991 ; number:2 ; pages:253-276 |
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NLEJ188296239 |
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520 | |a The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase high-performance liquid chromatographic (HPLC) system for the analysis of the intact CoA esters is described and their chromatographic behaviour documented. Reversed-phase HPLC systems for the analysis of the 4-bromophenacyl derivatives of the dicarboxylyl-mono-carnitines and the 4-nitrobenzyl derivatives of the free acids are also described. Some preliminary studies of the metabolism of [U-^1^4C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and rat skeletal muscle mitochondria are describedillustrating the application of these methods. | ||
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(DE-627)NLEJ188296239 (DE-599)GBVNLZ188296239 DE-627 ger DE-627 rakwb eng Synthesis, characterisation and high-performance liquid chromatography of C"6C"1"6 dicarboxylyl-mono-coenzyme A and -mono-carnitine esters 1991 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase high-performance liquid chromatographic (HPLC) system for the analysis of the intact CoA esters is described and their chromatographic behaviour documented. Reversed-phase HPLC systems for the analysis of the 4-bromophenacyl derivatives of the dicarboxylyl-mono-carnitines and the 4-nitrobenzyl derivatives of the free acids are also described. Some preliminary studies of the metabolism of [U-^1^4C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and rat skeletal muscle mitochondria are describedillustrating the application of these methods. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Pourfarzam, M. oth Bartlett, K. oth in Journal of Chromatography B: Biomedical Sciences and Applications Amsterdam : Elsevier 570(1991), 2, Seite 253-276 (DE-627)NLEJ177261676 (DE-600)1491259-4 0378-4347 nnns volume:570 year:1991 number:2 pages:253-276 http://linkinghub.elsevier.com/retrieve/pii/0378-4347(91)80529-L GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 570 1991 2 253-276 |
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(DE-627)NLEJ188296239 (DE-599)GBVNLZ188296239 DE-627 ger DE-627 rakwb eng Synthesis, characterisation and high-performance liquid chromatography of C"6C"1"6 dicarboxylyl-mono-coenzyme A and -mono-carnitine esters 1991 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase high-performance liquid chromatographic (HPLC) system for the analysis of the intact CoA esters is described and their chromatographic behaviour documented. Reversed-phase HPLC systems for the analysis of the 4-bromophenacyl derivatives of the dicarboxylyl-mono-carnitines and the 4-nitrobenzyl derivatives of the free acids are also described. Some preliminary studies of the metabolism of [U-^1^4C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and rat skeletal muscle mitochondria are describedillustrating the application of these methods. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Pourfarzam, M. oth Bartlett, K. oth in Journal of Chromatography B: Biomedical Sciences and Applications Amsterdam : Elsevier 570(1991), 2, Seite 253-276 (DE-627)NLEJ177261676 (DE-600)1491259-4 0378-4347 nnns volume:570 year:1991 number:2 pages:253-276 http://linkinghub.elsevier.com/retrieve/pii/0378-4347(91)80529-L GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 570 1991 2 253-276 |
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(DE-627)NLEJ188296239 (DE-599)GBVNLZ188296239 DE-627 ger DE-627 rakwb eng Synthesis, characterisation and high-performance liquid chromatography of C"6C"1"6 dicarboxylyl-mono-coenzyme A and -mono-carnitine esters 1991 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase high-performance liquid chromatographic (HPLC) system for the analysis of the intact CoA esters is described and their chromatographic behaviour documented. Reversed-phase HPLC systems for the analysis of the 4-bromophenacyl derivatives of the dicarboxylyl-mono-carnitines and the 4-nitrobenzyl derivatives of the free acids are also described. Some preliminary studies of the metabolism of [U-^1^4C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and rat skeletal muscle mitochondria are describedillustrating the application of these methods. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Pourfarzam, M. oth Bartlett, K. oth in Journal of Chromatography B: Biomedical Sciences and Applications Amsterdam : Elsevier 570(1991), 2, Seite 253-276 (DE-627)NLEJ177261676 (DE-600)1491259-4 0378-4347 nnns volume:570 year:1991 number:2 pages:253-276 http://linkinghub.elsevier.com/retrieve/pii/0378-4347(91)80529-L GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 570 1991 2 253-276 |
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(DE-627)NLEJ188296239 (DE-599)GBVNLZ188296239 DE-627 ger DE-627 rakwb eng Synthesis, characterisation and high-performance liquid chromatography of C"6C"1"6 dicarboxylyl-mono-coenzyme A and -mono-carnitine esters 1991 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase high-performance liquid chromatographic (HPLC) system for the analysis of the intact CoA esters is described and their chromatographic behaviour documented. Reversed-phase HPLC systems for the analysis of the 4-bromophenacyl derivatives of the dicarboxylyl-mono-carnitines and the 4-nitrobenzyl derivatives of the free acids are also described. Some preliminary studies of the metabolism of [U-^1^4C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and rat skeletal muscle mitochondria are describedillustrating the application of these methods. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Pourfarzam, M. oth Bartlett, K. oth in Journal of Chromatography B: Biomedical Sciences and Applications Amsterdam : Elsevier 570(1991), 2, Seite 253-276 (DE-627)NLEJ177261676 (DE-600)1491259-4 0378-4347 nnns volume:570 year:1991 number:2 pages:253-276 http://linkinghub.elsevier.com/retrieve/pii/0378-4347(91)80529-L GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 570 1991 2 253-276 |
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(DE-627)NLEJ188296239 (DE-599)GBVNLZ188296239 DE-627 ger DE-627 rakwb eng Synthesis, characterisation and high-performance liquid chromatography of C"6C"1"6 dicarboxylyl-mono-coenzyme A and -mono-carnitine esters 1991 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase high-performance liquid chromatographic (HPLC) system for the analysis of the intact CoA esters is described and their chromatographic behaviour documented. Reversed-phase HPLC systems for the analysis of the 4-bromophenacyl derivatives of the dicarboxylyl-mono-carnitines and the 4-nitrobenzyl derivatives of the free acids are also described. Some preliminary studies of the metabolism of [U-^1^4C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and rat skeletal muscle mitochondria are describedillustrating the application of these methods. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Pourfarzam, M. oth Bartlett, K. oth in Journal of Chromatography B: Biomedical Sciences and Applications Amsterdam : Elsevier 570(1991), 2, Seite 253-276 (DE-627)NLEJ177261676 (DE-600)1491259-4 0378-4347 nnns volume:570 year:1991 number:2 pages:253-276 http://linkinghub.elsevier.com/retrieve/pii/0378-4347(91)80529-L GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 570 1991 2 253-276 |
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Synthesis, characterisation and high-performance liquid chromatography of C"6C"1"6 dicarboxylyl-mono-coenzyme A and -mono-carnitine esters |
abstract |
The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase high-performance liquid chromatographic (HPLC) system for the analysis of the intact CoA esters is described and their chromatographic behaviour documented. Reversed-phase HPLC systems for the analysis of the 4-bromophenacyl derivatives of the dicarboxylyl-mono-carnitines and the 4-nitrobenzyl derivatives of the free acids are also described. Some preliminary studies of the metabolism of [U-^1^4C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and rat skeletal muscle mitochondria are describedillustrating the application of these methods. |
abstractGer |
The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase high-performance liquid chromatographic (HPLC) system for the analysis of the intact CoA esters is described and their chromatographic behaviour documented. Reversed-phase HPLC systems for the analysis of the 4-bromophenacyl derivatives of the dicarboxylyl-mono-carnitines and the 4-nitrobenzyl derivatives of the free acids are also described. Some preliminary studies of the metabolism of [U-^1^4C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and rat skeletal muscle mitochondria are describedillustrating the application of these methods. |
abstract_unstemmed |
The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase high-performance liquid chromatographic (HPLC) system for the analysis of the intact CoA esters is described and their chromatographic behaviour documented. Reversed-phase HPLC systems for the analysis of the 4-bromophenacyl derivatives of the dicarboxylyl-mono-carnitines and the 4-nitrobenzyl derivatives of the free acids are also described. Some preliminary studies of the metabolism of [U-^1^4C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and rat skeletal muscle mitochondria are describedillustrating the application of these methods. |
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Synthesis, characterisation and high-performance liquid chromatography of C"6C"1"6 dicarboxylyl-mono-coenzyme A and -mono-carnitine esters |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ188296239</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707094827.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070506s1991 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ188296239</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBVNLZ188296239</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Synthesis, characterisation and high-performance liquid chromatography of C"6C"1"6 dicarboxylyl-mono-coenzyme A and -mono-carnitine esters</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1991</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The synthesis and purification of the mono-coenzyme A and mono-carnitine esters of the homologous series of straight-chain even-numbered dicarboxylic acids (C"6C"1"6) is described. The corresponding 3-hydroxyacyl- and 2-enoyl-CoA esters were prepared enzymatically. A reversed-phase high-performance liquid chromatographic (HPLC) system for the analysis of the intact CoA esters is described and their chromatographic behaviour documented. Reversed-phase HPLC systems for the analysis of the 4-bromophenacyl derivatives of the dicarboxylyl-mono-carnitines and the 4-nitrobenzyl derivatives of the free acids are also described. Some preliminary studies of the metabolism of [U-^1^4C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and rat skeletal muscle mitochondria are describedillustrating the application of these methods.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Elsevier Journal Backfiles on ScienceDirect 1907 - 2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pourfarzam, M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bartlett, K.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Journal of Chromatography B: Biomedical Sciences and Applications</subfield><subfield code="d">Amsterdam : Elsevier</subfield><subfield code="g">570(1991), 2, Seite 253-276</subfield><subfield code="w">(DE-627)NLEJ177261676</subfield><subfield code="w">(DE-600)1491259-4</subfield><subfield code="x">0378-4347</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:570</subfield><subfield code="g">year:1991</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:253-276</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://linkinghub.elsevier.com/retrieve/pii/0378-4347(91)80529-L</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_H</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SDJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">570</subfield><subfield code="j">1991</subfield><subfield code="e">2</subfield><subfield code="h">253-276</subfield></datafield></record></collection>
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