Bone marrow regeneration under cytotoxic drug regimens: behaviour ranging from homeostasis to unpredictability in a model for hemopoietic differentiation
In the process of hemopoiesis, bone marrow stem cells differentiate into the various types of mature blood cells. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructiv...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1992 |
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| Reproduktion: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
|---|---|
| Übergeordnetes Werk: |
in: Biosystems - Amsterdam : Elsevier, 26(1992), 4, Seite 231-237 |
| Übergeordnetes Werk: |
volume:26 ; year:1992 ; number:4 ; pages:231-237 |
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| 520 | |a In the process of hemopoiesis, bone marrow stem cells differentiate into the various types of mature blood cells. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructive perturbations. Yet, a temporally stochastic perturbation results in chaoticlike behaviour which has no deterministic source. | ||
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(DE-627)NLEJ188915788 (DE-599)GBVNLZ188915788 DE-627 ger DE-627 rakwb eng Bone marrow regeneration under cytotoxic drug regimens: behaviour ranging from homeostasis to unpredictability in a model for hemopoietic differentiation 1992 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In the process of hemopoiesis, bone marrow stem cells differentiate into the various types of mature blood cells. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructive perturbations. Yet, a temporally stochastic perturbation results in chaoticlike behaviour which has no deterministic source. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Mehr, R. oth Agur, Z. oth in Biosystems Amsterdam : Elsevier 26(1992), 4, Seite 231-237 (DE-627)NLEJ188913130 (DE-600)1496359-0 0303-2647 nnns volume:26 year:1992 number:4 pages:231-237 http://dx.doi.org/10.1016/0303-2647(92)90028-W GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 26 1992 4 231-237 |
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(DE-627)NLEJ188915788 (DE-599)GBVNLZ188915788 DE-627 ger DE-627 rakwb eng Bone marrow regeneration under cytotoxic drug regimens: behaviour ranging from homeostasis to unpredictability in a model for hemopoietic differentiation 1992 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In the process of hemopoiesis, bone marrow stem cells differentiate into the various types of mature blood cells. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructive perturbations. Yet, a temporally stochastic perturbation results in chaoticlike behaviour which has no deterministic source. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Mehr, R. oth Agur, Z. oth in Biosystems Amsterdam : Elsevier 26(1992), 4, Seite 231-237 (DE-627)NLEJ188913130 (DE-600)1496359-0 0303-2647 nnns volume:26 year:1992 number:4 pages:231-237 http://dx.doi.org/10.1016/0303-2647(92)90028-W GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 26 1992 4 231-237 |
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(DE-627)NLEJ188915788 (DE-599)GBVNLZ188915788 DE-627 ger DE-627 rakwb eng Bone marrow regeneration under cytotoxic drug regimens: behaviour ranging from homeostasis to unpredictability in a model for hemopoietic differentiation 1992 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In the process of hemopoiesis, bone marrow stem cells differentiate into the various types of mature blood cells. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructive perturbations. Yet, a temporally stochastic perturbation results in chaoticlike behaviour which has no deterministic source. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Mehr, R. oth Agur, Z. oth in Biosystems Amsterdam : Elsevier 26(1992), 4, Seite 231-237 (DE-627)NLEJ188913130 (DE-600)1496359-0 0303-2647 nnns volume:26 year:1992 number:4 pages:231-237 http://dx.doi.org/10.1016/0303-2647(92)90028-W GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 26 1992 4 231-237 |
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(DE-627)NLEJ188915788 (DE-599)GBVNLZ188915788 DE-627 ger DE-627 rakwb eng Bone marrow regeneration under cytotoxic drug regimens: behaviour ranging from homeostasis to unpredictability in a model for hemopoietic differentiation 1992 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In the process of hemopoiesis, bone marrow stem cells differentiate into the various types of mature blood cells. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructive perturbations. Yet, a temporally stochastic perturbation results in chaoticlike behaviour which has no deterministic source. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Mehr, R. oth Agur, Z. oth in Biosystems Amsterdam : Elsevier 26(1992), 4, Seite 231-237 (DE-627)NLEJ188913130 (DE-600)1496359-0 0303-2647 nnns volume:26 year:1992 number:4 pages:231-237 http://dx.doi.org/10.1016/0303-2647(92)90028-W GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 26 1992 4 231-237 |
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(DE-627)NLEJ188915788 (DE-599)GBVNLZ188915788 DE-627 ger DE-627 rakwb eng Bone marrow regeneration under cytotoxic drug regimens: behaviour ranging from homeostasis to unpredictability in a model for hemopoietic differentiation 1992 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In the process of hemopoiesis, bone marrow stem cells differentiate into the various types of mature blood cells. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructive perturbations. Yet, a temporally stochastic perturbation results in chaoticlike behaviour which has no deterministic source. Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 Mehr, R. oth Agur, Z. oth in Biosystems Amsterdam : Elsevier 26(1992), 4, Seite 231-237 (DE-627)NLEJ188913130 (DE-600)1496359-0 0303-2647 nnns volume:26 year:1992 number:4 pages:231-237 http://dx.doi.org/10.1016/0303-2647(92)90028-W GBV_USEFLAG_H ZDB-1-SDJ GBV_NL_ARTICLE AR 26 1992 4 231-237 |
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bone marrow regeneration under cytotoxic drug regimens: behaviour ranging from homeostasis to unpredictability in a model for hemopoietic differentiation |
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Bone marrow regeneration under cytotoxic drug regimens: behaviour ranging from homeostasis to unpredictability in a model for hemopoietic differentiation |
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In the process of hemopoiesis, bone marrow stem cells differentiate into the various types of mature blood cells. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructive perturbations. Yet, a temporally stochastic perturbation results in chaoticlike behaviour which has no deterministic source. |
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In the process of hemopoiesis, bone marrow stem cells differentiate into the various types of mature blood cells. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructive perturbations. Yet, a temporally stochastic perturbation results in chaoticlike behaviour which has no deterministic source. |
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In the process of hemopoiesis, bone marrow stem cells differentiate into the various types of mature blood cells. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructive perturbations. Yet, a temporally stochastic perturbation results in chaoticlike behaviour which has no deterministic source. |
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