Correlation between the physiological state of bacteria and the radioprotective effectiveness of cysteine
Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase c...
Ausführliche Beschreibung
Autor*in: |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
1968 |
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Umfang: |
8 |
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Springer Online Journal Archives 1860-2002 |
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Übergeordnetes Werk: |
in: Archives of microbiology - 1930, 61(1968) vom: Apr., Seite 327-334 |
Übergeordnetes Werk: |
volume:61 ; year:1968 ; month:04 ; pages:327-334 ; extent:8 |
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NLEJ200212745 |
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520 | |a Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase cells, while the radiosensitivity of stat-phase bacteria remained unchanged. The biochemical background of this phenomenon was also studied by means of 35S-Cysteine. The extent and distribution of cysteine incorporation into the fractions of log-phase cells were found to differ from those occurring in the fractions of statphase cells. The biochemical radioprotective effect of cysteine described above suggests two different explanations: a) the radioresistance induced by cysteine presupposes an active metabolic state of the cells, which may correlate with the induction of the repair systems; b) the cysteine incorporated by the cells provides a radio-protective effect; hence only the radiosensitivity of log-phase cells decreases, while that of the stationary phase cells remains unchanged owing to their inability to incorporate cysteine in an amount rendering them effective radioprotectors. | ||
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700 | 1 | |a Nagy, Zs. |4 oth | |
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(DE-627)NLEJ200212745 DE-627 ger DE-627 rakwb eng Correlation between the physiological state of bacteria and the radioprotective effectiveness of cysteine 1968 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase cells, while the radiosensitivity of stat-phase bacteria remained unchanged. The biochemical background of this phenomenon was also studied by means of 35S-Cysteine. The extent and distribution of cysteine incorporation into the fractions of log-phase cells were found to differ from those occurring in the fractions of statphase cells. The biochemical radioprotective effect of cysteine described above suggests two different explanations: a) the radioresistance induced by cysteine presupposes an active metabolic state of the cells, which may correlate with the induction of the repair systems; b) the cysteine incorporated by the cells provides a radio-protective effect; hence only the radiosensitivity of log-phase cells decreases, while that of the stationary phase cells remains unchanged owing to their inability to incorporate cysteine in an amount rendering them effective radioprotectors. Springer Online Journal Archives 1860-2002 Nagy, Zs. oth Hernádi, F. oth Kovács, P. oth Vályi-Nagy, T. oth in Archives of microbiology 1930 61(1968) vom: Apr., Seite 327-334 (DE-627)NLEJ188986545 (DE-600)1458451-7 1432-072X nnns volume:61 year:1968 month:04 pages:327-334 extent:8 http://dx.doi.org/10.1007/BF00409669 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 61 1968 4 327-334 8 |
spelling |
(DE-627)NLEJ200212745 DE-627 ger DE-627 rakwb eng Correlation between the physiological state of bacteria and the radioprotective effectiveness of cysteine 1968 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase cells, while the radiosensitivity of stat-phase bacteria remained unchanged. The biochemical background of this phenomenon was also studied by means of 35S-Cysteine. The extent and distribution of cysteine incorporation into the fractions of log-phase cells were found to differ from those occurring in the fractions of statphase cells. The biochemical radioprotective effect of cysteine described above suggests two different explanations: a) the radioresistance induced by cysteine presupposes an active metabolic state of the cells, which may correlate with the induction of the repair systems; b) the cysteine incorporated by the cells provides a radio-protective effect; hence only the radiosensitivity of log-phase cells decreases, while that of the stationary phase cells remains unchanged owing to their inability to incorporate cysteine in an amount rendering them effective radioprotectors. Springer Online Journal Archives 1860-2002 Nagy, Zs. oth Hernádi, F. oth Kovács, P. oth Vályi-Nagy, T. oth in Archives of microbiology 1930 61(1968) vom: Apr., Seite 327-334 (DE-627)NLEJ188986545 (DE-600)1458451-7 1432-072X nnns volume:61 year:1968 month:04 pages:327-334 extent:8 http://dx.doi.org/10.1007/BF00409669 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 61 1968 4 327-334 8 |
allfields_unstemmed |
(DE-627)NLEJ200212745 DE-627 ger DE-627 rakwb eng Correlation between the physiological state of bacteria and the radioprotective effectiveness of cysteine 1968 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase cells, while the radiosensitivity of stat-phase bacteria remained unchanged. The biochemical background of this phenomenon was also studied by means of 35S-Cysteine. The extent and distribution of cysteine incorporation into the fractions of log-phase cells were found to differ from those occurring in the fractions of statphase cells. The biochemical radioprotective effect of cysteine described above suggests two different explanations: a) the radioresistance induced by cysteine presupposes an active metabolic state of the cells, which may correlate with the induction of the repair systems; b) the cysteine incorporated by the cells provides a radio-protective effect; hence only the radiosensitivity of log-phase cells decreases, while that of the stationary phase cells remains unchanged owing to their inability to incorporate cysteine in an amount rendering them effective radioprotectors. Springer Online Journal Archives 1860-2002 Nagy, Zs. oth Hernádi, F. oth Kovács, P. oth Vályi-Nagy, T. oth in Archives of microbiology 1930 61(1968) vom: Apr., Seite 327-334 (DE-627)NLEJ188986545 (DE-600)1458451-7 1432-072X nnns volume:61 year:1968 month:04 pages:327-334 extent:8 http://dx.doi.org/10.1007/BF00409669 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 61 1968 4 327-334 8 |
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(DE-627)NLEJ200212745 DE-627 ger DE-627 rakwb eng Correlation between the physiological state of bacteria and the radioprotective effectiveness of cysteine 1968 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase cells, while the radiosensitivity of stat-phase bacteria remained unchanged. The biochemical background of this phenomenon was also studied by means of 35S-Cysteine. The extent and distribution of cysteine incorporation into the fractions of log-phase cells were found to differ from those occurring in the fractions of statphase cells. The biochemical radioprotective effect of cysteine described above suggests two different explanations: a) the radioresistance induced by cysteine presupposes an active metabolic state of the cells, which may correlate with the induction of the repair systems; b) the cysteine incorporated by the cells provides a radio-protective effect; hence only the radiosensitivity of log-phase cells decreases, while that of the stationary phase cells remains unchanged owing to their inability to incorporate cysteine in an amount rendering them effective radioprotectors. Springer Online Journal Archives 1860-2002 Nagy, Zs. oth Hernádi, F. oth Kovács, P. oth Vályi-Nagy, T. oth in Archives of microbiology 1930 61(1968) vom: Apr., Seite 327-334 (DE-627)NLEJ188986545 (DE-600)1458451-7 1432-072X nnns volume:61 year:1968 month:04 pages:327-334 extent:8 http://dx.doi.org/10.1007/BF00409669 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 61 1968 4 327-334 8 |
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(DE-627)NLEJ200212745 DE-627 ger DE-627 rakwb eng Correlation between the physiological state of bacteria and the radioprotective effectiveness of cysteine 1968 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase cells, while the radiosensitivity of stat-phase bacteria remained unchanged. The biochemical background of this phenomenon was also studied by means of 35S-Cysteine. The extent and distribution of cysteine incorporation into the fractions of log-phase cells were found to differ from those occurring in the fractions of statphase cells. The biochemical radioprotective effect of cysteine described above suggests two different explanations: a) the radioresistance induced by cysteine presupposes an active metabolic state of the cells, which may correlate with the induction of the repair systems; b) the cysteine incorporated by the cells provides a radio-protective effect; hence only the radiosensitivity of log-phase cells decreases, while that of the stationary phase cells remains unchanged owing to their inability to incorporate cysteine in an amount rendering them effective radioprotectors. Springer Online Journal Archives 1860-2002 Nagy, Zs. oth Hernádi, F. oth Kovács, P. oth Vályi-Nagy, T. oth in Archives of microbiology 1930 61(1968) vom: Apr., Seite 327-334 (DE-627)NLEJ188986545 (DE-600)1458451-7 1432-072X nnns volume:61 year:1968 month:04 pages:327-334 extent:8 http://dx.doi.org/10.1007/BF00409669 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 61 1968 4 327-334 8 |
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correlation between the physiological state of bacteria and the radioprotective effectiveness of cysteine |
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Correlation between the physiological state of bacteria and the radioprotective effectiveness of cysteine |
abstract |
Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase cells, while the radiosensitivity of stat-phase bacteria remained unchanged. The biochemical background of this phenomenon was also studied by means of 35S-Cysteine. The extent and distribution of cysteine incorporation into the fractions of log-phase cells were found to differ from those occurring in the fractions of statphase cells. The biochemical radioprotective effect of cysteine described above suggests two different explanations: a) the radioresistance induced by cysteine presupposes an active metabolic state of the cells, which may correlate with the induction of the repair systems; b) the cysteine incorporated by the cells provides a radio-protective effect; hence only the radiosensitivity of log-phase cells decreases, while that of the stationary phase cells remains unchanged owing to their inability to incorporate cysteine in an amount rendering them effective radioprotectors. |
abstractGer |
Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase cells, while the radiosensitivity of stat-phase bacteria remained unchanged. The biochemical background of this phenomenon was also studied by means of 35S-Cysteine. The extent and distribution of cysteine incorporation into the fractions of log-phase cells were found to differ from those occurring in the fractions of statphase cells. The biochemical radioprotective effect of cysteine described above suggests two different explanations: a) the radioresistance induced by cysteine presupposes an active metabolic state of the cells, which may correlate with the induction of the repair systems; b) the cysteine incorporated by the cells provides a radio-protective effect; hence only the radiosensitivity of log-phase cells decreases, while that of the stationary phase cells remains unchanged owing to their inability to incorporate cysteine in an amount rendering them effective radioprotectors. |
abstract_unstemmed |
Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase cells, while the radiosensitivity of stat-phase bacteria remained unchanged. The biochemical background of this phenomenon was also studied by means of 35S-Cysteine. The extent and distribution of cysteine incorporation into the fractions of log-phase cells were found to differ from those occurring in the fractions of statphase cells. The biochemical radioprotective effect of cysteine described above suggests two different explanations: a) the radioresistance induced by cysteine presupposes an active metabolic state of the cells, which may correlate with the induction of the repair systems; b) the cysteine incorporated by the cells provides a radio-protective effect; hence only the radiosensitivity of log-phase cells decreases, while that of the stationary phase cells remains unchanged owing to their inability to incorporate cysteine in an amount rendering them effective radioprotectors. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ200212745</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210706042826.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070527s1968 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ200212745</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Correlation between the physiological state of bacteria and the radioprotective effectiveness of cysteine</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1968</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">8</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Summary E. coli 15 T - cells were cultured in the presence of cysteine, then removed and subjected to X-ray irradiation in cysteine-free buffer. The radiation-sensitivity was then found to decrease in inverse ratio to the concentration of cysteine used. This phenomenon occurred only with log-phase cells, while the radiosensitivity of stat-phase bacteria remained unchanged. The biochemical background of this phenomenon was also studied by means of 35S-Cysteine. The extent and distribution of cysteine incorporation into the fractions of log-phase cells were found to differ from those occurring in the fractions of statphase cells. The biochemical radioprotective effect of cysteine described above suggests two different explanations: a) the radioresistance induced by cysteine presupposes an active metabolic state of the cells, which may correlate with the induction of the repair systems; b) the cysteine incorporated by the cells provides a radio-protective effect; hence only the radiosensitivity of log-phase cells decreases, while that of the stationary phase cells remains unchanged owing to their inability to incorporate cysteine in an amount rendering them effective radioprotectors.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Springer Online Journal Archives 1860-2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nagy, Zs.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hernádi, F.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kovács, P.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Vályi-Nagy, T.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Archives of microbiology</subfield><subfield code="d">1930</subfield><subfield code="g">61(1968) vom: Apr., Seite 327-334</subfield><subfield code="w">(DE-627)NLEJ188986545</subfield><subfield code="w">(DE-600)1458451-7</subfield><subfield code="x">1432-072X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:61</subfield><subfield code="g">year:1968</subfield><subfield code="g">month:04</subfield><subfield code="g">pages:327-334</subfield><subfield code="g">extent:8</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1007/BF00409669</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SOJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">61</subfield><subfield code="j">1968</subfield><subfield code="c">4</subfield><subfield code="h">327-334</subfield><subfield code="g">8</subfield></datafield></record></collection>
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