Electrical and mechanical properties and neuro-effector transmission in the smooth muscle layer of the guinea-pig ileocecal junction
Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smoo...
Ausführliche Beschreibung
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| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1982 |
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| Umfang: |
7 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: Pflügers Archiv - 1868, 394(1982) vom: Apr., Seite 355-361 |
| Übergeordnetes Werk: |
volume:394 ; year:1982 ; month:04 ; pages:355-361 ; extent:7 |
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| 245 | 1 | 0 | |a Electrical and mechanical properties and neuro-effector transmission in the smooth muscle layer of the guinea-pig ileocecal junction |
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| 520 | |a Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smooth muscle was low (−43 mV) compared with the membrane potential of circular muscle cells of the ileum or caecum (−58 mV or −62mV). Only small populations of the muscle cells (about 5%) generated spontaneous action potentials. Field stimulation of the tissue produced an initial slight relaxation followed by a contraction, and the mechanical responses were accompanied by membrane hyperpolarization (i. j. p.) followed by repolarization with rebound spikes. Treatment with atropine increased the amplitude of i.j. ps and decreased the amplitue of the rebound repolarization. Propranolol or phentolamine did not affect the amplitude of i. j. p., however, phentolamine slightly reduced the amplitude of the rebound repolarization. These results indicate that the ileocecal junction is predominantly controlled by non-adrenergic, non-cholinergic inhibitory nerve fibres and that the distribution of adrenergic and cholinergic excitatory nerve fibres is sparse. | ||
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(DE-627)NLEJ200971999 DE-627 ger DE-627 rakwb eng Electrical and mechanical properties and neuro-effector transmission in the smooth muscle layer of the guinea-pig ileocecal junction 1982 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smooth muscle was low (−43 mV) compared with the membrane potential of circular muscle cells of the ileum or caecum (−58 mV or −62mV). Only small populations of the muscle cells (about 5%) generated spontaneous action potentials. Field stimulation of the tissue produced an initial slight relaxation followed by a contraction, and the mechanical responses were accompanied by membrane hyperpolarization (i. j. p.) followed by repolarization with rebound spikes. Treatment with atropine increased the amplitude of i.j. ps and decreased the amplitue of the rebound repolarization. Propranolol or phentolamine did not affect the amplitude of i. j. p., however, phentolamine slightly reduced the amplitude of the rebound repolarization. These results indicate that the ileocecal junction is predominantly controlled by non-adrenergic, non-cholinergic inhibitory nerve fibres and that the distribution of adrenergic and cholinergic excitatory nerve fibres is sparse. Springer Online Journal Archives 1860-2002 Kubota, Masayuki oth in Pflügers Archiv 1868 394(1982) vom: Apr., Seite 355-361 (DE-627)NLEJ188987363 (DE-600)1463014-x 1432-2013 nnns volume:394 year:1982 month:04 pages:355-361 extent:7 http://dx.doi.org/10.1007/BF00583701 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 394 1982 4 355-361 7 |
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(DE-627)NLEJ200971999 DE-627 ger DE-627 rakwb eng Electrical and mechanical properties and neuro-effector transmission in the smooth muscle layer of the guinea-pig ileocecal junction 1982 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smooth muscle was low (−43 mV) compared with the membrane potential of circular muscle cells of the ileum or caecum (−58 mV or −62mV). Only small populations of the muscle cells (about 5%) generated spontaneous action potentials. Field stimulation of the tissue produced an initial slight relaxation followed by a contraction, and the mechanical responses were accompanied by membrane hyperpolarization (i. j. p.) followed by repolarization with rebound spikes. Treatment with atropine increased the amplitude of i.j. ps and decreased the amplitue of the rebound repolarization. Propranolol or phentolamine did not affect the amplitude of i. j. p., however, phentolamine slightly reduced the amplitude of the rebound repolarization. These results indicate that the ileocecal junction is predominantly controlled by non-adrenergic, non-cholinergic inhibitory nerve fibres and that the distribution of adrenergic and cholinergic excitatory nerve fibres is sparse. Springer Online Journal Archives 1860-2002 Kubota, Masayuki oth in Pflügers Archiv 1868 394(1982) vom: Apr., Seite 355-361 (DE-627)NLEJ188987363 (DE-600)1463014-x 1432-2013 nnns volume:394 year:1982 month:04 pages:355-361 extent:7 http://dx.doi.org/10.1007/BF00583701 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 394 1982 4 355-361 7 |
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(DE-627)NLEJ200971999 DE-627 ger DE-627 rakwb eng Electrical and mechanical properties and neuro-effector transmission in the smooth muscle layer of the guinea-pig ileocecal junction 1982 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smooth muscle was low (−43 mV) compared with the membrane potential of circular muscle cells of the ileum or caecum (−58 mV or −62mV). Only small populations of the muscle cells (about 5%) generated spontaneous action potentials. Field stimulation of the tissue produced an initial slight relaxation followed by a contraction, and the mechanical responses were accompanied by membrane hyperpolarization (i. j. p.) followed by repolarization with rebound spikes. Treatment with atropine increased the amplitude of i.j. ps and decreased the amplitue of the rebound repolarization. Propranolol or phentolamine did not affect the amplitude of i. j. p., however, phentolamine slightly reduced the amplitude of the rebound repolarization. These results indicate that the ileocecal junction is predominantly controlled by non-adrenergic, non-cholinergic inhibitory nerve fibres and that the distribution of adrenergic and cholinergic excitatory nerve fibres is sparse. Springer Online Journal Archives 1860-2002 Kubota, Masayuki oth in Pflügers Archiv 1868 394(1982) vom: Apr., Seite 355-361 (DE-627)NLEJ188987363 (DE-600)1463014-x 1432-2013 nnns volume:394 year:1982 month:04 pages:355-361 extent:7 http://dx.doi.org/10.1007/BF00583701 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 394 1982 4 355-361 7 |
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(DE-627)NLEJ200971999 DE-627 ger DE-627 rakwb eng Electrical and mechanical properties and neuro-effector transmission in the smooth muscle layer of the guinea-pig ileocecal junction 1982 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smooth muscle was low (−43 mV) compared with the membrane potential of circular muscle cells of the ileum or caecum (−58 mV or −62mV). Only small populations of the muscle cells (about 5%) generated spontaneous action potentials. Field stimulation of the tissue produced an initial slight relaxation followed by a contraction, and the mechanical responses were accompanied by membrane hyperpolarization (i. j. p.) followed by repolarization with rebound spikes. Treatment with atropine increased the amplitude of i.j. ps and decreased the amplitue of the rebound repolarization. Propranolol or phentolamine did not affect the amplitude of i. j. p., however, phentolamine slightly reduced the amplitude of the rebound repolarization. These results indicate that the ileocecal junction is predominantly controlled by non-adrenergic, non-cholinergic inhibitory nerve fibres and that the distribution of adrenergic and cholinergic excitatory nerve fibres is sparse. Springer Online Journal Archives 1860-2002 Kubota, Masayuki oth in Pflügers Archiv 1868 394(1982) vom: Apr., Seite 355-361 (DE-627)NLEJ188987363 (DE-600)1463014-x 1432-2013 nnns volume:394 year:1982 month:04 pages:355-361 extent:7 http://dx.doi.org/10.1007/BF00583701 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 394 1982 4 355-361 7 |
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(DE-627)NLEJ200971999 DE-627 ger DE-627 rakwb eng Electrical and mechanical properties and neuro-effector transmission in the smooth muscle layer of the guinea-pig ileocecal junction 1982 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smooth muscle was low (−43 mV) compared with the membrane potential of circular muscle cells of the ileum or caecum (−58 mV or −62mV). Only small populations of the muscle cells (about 5%) generated spontaneous action potentials. Field stimulation of the tissue produced an initial slight relaxation followed by a contraction, and the mechanical responses were accompanied by membrane hyperpolarization (i. j. p.) followed by repolarization with rebound spikes. Treatment with atropine increased the amplitude of i.j. ps and decreased the amplitue of the rebound repolarization. Propranolol or phentolamine did not affect the amplitude of i. j. p., however, phentolamine slightly reduced the amplitude of the rebound repolarization. These results indicate that the ileocecal junction is predominantly controlled by non-adrenergic, non-cholinergic inhibitory nerve fibres and that the distribution of adrenergic and cholinergic excitatory nerve fibres is sparse. Springer Online Journal Archives 1860-2002 Kubota, Masayuki oth in Pflügers Archiv 1868 394(1982) vom: Apr., Seite 355-361 (DE-627)NLEJ188987363 (DE-600)1463014-x 1432-2013 nnns volume:394 year:1982 month:04 pages:355-361 extent:7 http://dx.doi.org/10.1007/BF00583701 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 394 1982 4 355-361 7 |
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Electrical and mechanical properties and neuro-effector transmission in the smooth muscle layer of the guinea-pig ileocecal junction |
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Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smooth muscle was low (−43 mV) compared with the membrane potential of circular muscle cells of the ileum or caecum (−58 mV or −62mV). Only small populations of the muscle cells (about 5%) generated spontaneous action potentials. Field stimulation of the tissue produced an initial slight relaxation followed by a contraction, and the mechanical responses were accompanied by membrane hyperpolarization (i. j. p.) followed by repolarization with rebound spikes. Treatment with atropine increased the amplitude of i.j. ps and decreased the amplitue of the rebound repolarization. Propranolol or phentolamine did not affect the amplitude of i. j. p., however, phentolamine slightly reduced the amplitude of the rebound repolarization. These results indicate that the ileocecal junction is predominantly controlled by non-adrenergic, non-cholinergic inhibitory nerve fibres and that the distribution of adrenergic and cholinergic excitatory nerve fibres is sparse. |
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Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smooth muscle was low (−43 mV) compared with the membrane potential of circular muscle cells of the ileum or caecum (−58 mV or −62mV). Only small populations of the muscle cells (about 5%) generated spontaneous action potentials. Field stimulation of the tissue produced an initial slight relaxation followed by a contraction, and the mechanical responses were accompanied by membrane hyperpolarization (i. j. p.) followed by repolarization with rebound spikes. Treatment with atropine increased the amplitude of i.j. ps and decreased the amplitue of the rebound repolarization. Propranolol or phentolamine did not affect the amplitude of i. j. p., however, phentolamine slightly reduced the amplitude of the rebound repolarization. These results indicate that the ileocecal junction is predominantly controlled by non-adrenergic, non-cholinergic inhibitory nerve fibres and that the distribution of adrenergic and cholinergic excitatory nerve fibres is sparse. |
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Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smooth muscle was low (−43 mV) compared with the membrane potential of circular muscle cells of the ileum or caecum (−58 mV or −62mV). Only small populations of the muscle cells (about 5%) generated spontaneous action potentials. Field stimulation of the tissue produced an initial slight relaxation followed by a contraction, and the mechanical responses were accompanied by membrane hyperpolarization (i. j. p.) followed by repolarization with rebound spikes. Treatment with atropine increased the amplitude of i.j. ps and decreased the amplitue of the rebound repolarization. Propranolol or phentolamine did not affect the amplitude of i. j. p., however, phentolamine slightly reduced the amplitude of the rebound repolarization. These results indicate that the ileocecal junction is predominantly controlled by non-adrenergic, non-cholinergic inhibitory nerve fibres and that the distribution of adrenergic and cholinergic excitatory nerve fibres is sparse. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ200971999</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210706064037.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070527s1982 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ200971999</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Electrical and mechanical properties and neuro-effector transmission in the smooth muscle layer of the guinea-pig ileocecal junction</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1982</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">7</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Electrical and mechanical properties and neuro-effector transmission were studied in circular strips of smooth muscle taken from the ileocecal junction of guinea-pigs in relation to sphincter action, using the microelectrode, and tension recording methods. The membrane potential of the smooth muscle was low (−43 mV) compared with the membrane potential of circular muscle cells of the ileum or caecum (−58 mV or −62mV). Only small populations of the muscle cells (about 5%) generated spontaneous action potentials. Field stimulation of the tissue produced an initial slight relaxation followed by a contraction, and the mechanical responses were accompanied by membrane hyperpolarization (i. j. p.) followed by repolarization with rebound spikes. Treatment with atropine increased the amplitude of i.j. ps and decreased the amplitue of the rebound repolarization. Propranolol or phentolamine did not affect the amplitude of i. j. p., however, phentolamine slightly reduced the amplitude of the rebound repolarization. These results indicate that the ileocecal junction is predominantly controlled by non-adrenergic, non-cholinergic inhibitory nerve fibres and that the distribution of adrenergic and cholinergic excitatory nerve fibres is sparse.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Springer Online Journal Archives 1860-2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kubota, Masayuki</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Pflügers Archiv</subfield><subfield code="d">1868</subfield><subfield code="g">394(1982) vom: Apr., Seite 355-361</subfield><subfield code="w">(DE-627)NLEJ188987363</subfield><subfield code="w">(DE-600)1463014-x</subfield><subfield code="x">1432-2013</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:394</subfield><subfield code="g">year:1982</subfield><subfield code="g">month:04</subfield><subfield code="g">pages:355-361</subfield><subfield code="g">extent:7</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1007/BF00583701</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SOJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">394</subfield><subfield code="j">1982</subfield><subfield code="c">4</subfield><subfield code="h">355-361</subfield><subfield code="g">7</subfield></datafield></record></collection>
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