Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells
Abstract Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors responsible for this high K+ sensitivity were examined. Using whole-cell voltage-clamp technique we found that both T-type and L-ty...
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| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1998 |
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| Umfang: |
3 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: Pflügers Archiv - 1868, 435(1998) vom: März, Seite 429-431 |
| Übergeordnetes Werk: |
volume:435 ; year:1998 ; month:03 ; pages:429-431 ; extent:3 |
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| 245 | 1 | 0 | |a Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells |
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| 520 | |a Abstract Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors responsible for this high K+ sensitivity were examined. Using whole-cell voltage-clamp technique we found that both T-type and L-type voltage-dependent Ca2+ channels have very low threshold potential (–71 and –58 mV, resp.). By means of patch-clamp technique combined with single-cell fluorimetry we also provided evidence that the activation of Igl, a K+-activated inward rectifying current is associated with Ca2+ influx. Both the low activation threshold of voltage-dependent Ca2+ channels and the function of Igl contribute to the exceptional K+ sensitivity of the glomerulosa cells. | ||
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| 700 | 1 | |a Várnai, Péter |4 oth | |
| 700 | 1 | |a Petheö, Gábor L. |4 oth | |
| 700 | 1 | |a Makara, Judit K. |4 oth | |
| 700 | 1 | |a Spät, András |4 oth | |
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(DE-627)NLEJ201013231 DE-627 ger DE-627 rakwb eng Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells 1998 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors responsible for this high K+ sensitivity were examined. Using whole-cell voltage-clamp technique we found that both T-type and L-type voltage-dependent Ca2+ channels have very low threshold potential (–71 and –58 mV, resp.). By means of patch-clamp technique combined with single-cell fluorimetry we also provided evidence that the activation of Igl, a K+-activated inward rectifying current is associated with Ca2+ influx. Both the low activation threshold of voltage-dependent Ca2+ channels and the function of Igl contribute to the exceptional K+ sensitivity of the glomerulosa cells. Springer Online Journal Archives 1860-2002 Várnai, Péter oth Petheö, Gábor L. oth Makara, Judit K. oth Spät, András oth in Pflügers Archiv 1868 435(1998) vom: März, Seite 429-431 (DE-627)NLEJ188987363 (DE-600)1463014-x 1432-2013 nnns volume:435 year:1998 month:03 pages:429-431 extent:3 http://dx.doi.org/10.1007/s004240050534 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 435 1998 3 429-431 3 |
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(DE-627)NLEJ201013231 DE-627 ger DE-627 rakwb eng Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells 1998 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors responsible for this high K+ sensitivity were examined. Using whole-cell voltage-clamp technique we found that both T-type and L-type voltage-dependent Ca2+ channels have very low threshold potential (–71 and –58 mV, resp.). By means of patch-clamp technique combined with single-cell fluorimetry we also provided evidence that the activation of Igl, a K+-activated inward rectifying current is associated with Ca2+ influx. Both the low activation threshold of voltage-dependent Ca2+ channels and the function of Igl contribute to the exceptional K+ sensitivity of the glomerulosa cells. Springer Online Journal Archives 1860-2002 Várnai, Péter oth Petheö, Gábor L. oth Makara, Judit K. oth Spät, András oth in Pflügers Archiv 1868 435(1998) vom: März, Seite 429-431 (DE-627)NLEJ188987363 (DE-600)1463014-x 1432-2013 nnns volume:435 year:1998 month:03 pages:429-431 extent:3 http://dx.doi.org/10.1007/s004240050534 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 435 1998 3 429-431 3 |
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(DE-627)NLEJ201013231 DE-627 ger DE-627 rakwb eng Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells 1998 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors responsible for this high K+ sensitivity were examined. Using whole-cell voltage-clamp technique we found that both T-type and L-type voltage-dependent Ca2+ channels have very low threshold potential (–71 and –58 mV, resp.). By means of patch-clamp technique combined with single-cell fluorimetry we also provided evidence that the activation of Igl, a K+-activated inward rectifying current is associated with Ca2+ influx. Both the low activation threshold of voltage-dependent Ca2+ channels and the function of Igl contribute to the exceptional K+ sensitivity of the glomerulosa cells. Springer Online Journal Archives 1860-2002 Várnai, Péter oth Petheö, Gábor L. oth Makara, Judit K. oth Spät, András oth in Pflügers Archiv 1868 435(1998) vom: März, Seite 429-431 (DE-627)NLEJ188987363 (DE-600)1463014-x 1432-2013 nnns volume:435 year:1998 month:03 pages:429-431 extent:3 http://dx.doi.org/10.1007/s004240050534 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 435 1998 3 429-431 3 |
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(DE-627)NLEJ201013231 DE-627 ger DE-627 rakwb eng Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells 1998 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors responsible for this high K+ sensitivity were examined. Using whole-cell voltage-clamp technique we found that both T-type and L-type voltage-dependent Ca2+ channels have very low threshold potential (–71 and –58 mV, resp.). By means of patch-clamp technique combined with single-cell fluorimetry we also provided evidence that the activation of Igl, a K+-activated inward rectifying current is associated with Ca2+ influx. Both the low activation threshold of voltage-dependent Ca2+ channels and the function of Igl contribute to the exceptional K+ sensitivity of the glomerulosa cells. Springer Online Journal Archives 1860-2002 Várnai, Péter oth Petheö, Gábor L. oth Makara, Judit K. oth Spät, András oth in Pflügers Archiv 1868 435(1998) vom: März, Seite 429-431 (DE-627)NLEJ188987363 (DE-600)1463014-x 1432-2013 nnns volume:435 year:1998 month:03 pages:429-431 extent:3 http://dx.doi.org/10.1007/s004240050534 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 435 1998 3 429-431 3 |
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(DE-627)NLEJ201013231 DE-627 ger DE-627 rakwb eng Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells 1998 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors responsible for this high K+ sensitivity were examined. Using whole-cell voltage-clamp technique we found that both T-type and L-type voltage-dependent Ca2+ channels have very low threshold potential (–71 and –58 mV, resp.). By means of patch-clamp technique combined with single-cell fluorimetry we also provided evidence that the activation of Igl, a K+-activated inward rectifying current is associated with Ca2+ influx. Both the low activation threshold of voltage-dependent Ca2+ channels and the function of Igl contribute to the exceptional K+ sensitivity of the glomerulosa cells. Springer Online Journal Archives 1860-2002 Várnai, Péter oth Petheö, Gábor L. oth Makara, Judit K. oth Spät, András oth in Pflügers Archiv 1868 435(1998) vom: März, Seite 429-431 (DE-627)NLEJ188987363 (DE-600)1463014-x 1432-2013 nnns volume:435 year:1998 month:03 pages:429-431 extent:3 http://dx.doi.org/10.1007/s004240050534 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 435 1998 3 429-431 3 |
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electrophysiological study on the high k+ sensitivity of rat glomerulosa cells |
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Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells |
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Abstract Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors responsible for this high K+ sensitivity were examined. Using whole-cell voltage-clamp technique we found that both T-type and L-type voltage-dependent Ca2+ channels have very low threshold potential (–71 and –58 mV, resp.). By means of patch-clamp technique combined with single-cell fluorimetry we also provided evidence that the activation of Igl, a K+-activated inward rectifying current is associated with Ca2+ influx. Both the low activation threshold of voltage-dependent Ca2+ channels and the function of Igl contribute to the exceptional K+ sensitivity of the glomerulosa cells. |
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Abstract Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors responsible for this high K+ sensitivity were examined. Using whole-cell voltage-clamp technique we found that both T-type and L-type voltage-dependent Ca2+ channels have very low threshold potential (–71 and –58 mV, resp.). By means of patch-clamp technique combined with single-cell fluorimetry we also provided evidence that the activation of Igl, a K+-activated inward rectifying current is associated with Ca2+ influx. Both the low activation threshold of voltage-dependent Ca2+ channels and the function of Igl contribute to the exceptional K+ sensitivity of the glomerulosa cells. |
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Abstract Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors responsible for this high K+ sensitivity were examined. Using whole-cell voltage-clamp technique we found that both T-type and L-type voltage-dependent Ca2+ channels have very low threshold potential (–71 and –58 mV, resp.). By means of patch-clamp technique combined with single-cell fluorimetry we also provided evidence that the activation of Igl, a K+-activated inward rectifying current is associated with Ca2+ influx. Both the low activation threshold of voltage-dependent Ca2+ channels and the function of Igl contribute to the exceptional K+ sensitivity of the glomerulosa cells. |
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