Inhibition of postprandial colonic motility by sulpiride in patients with irritable colon
Summary Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present investigation the motor response of the pelvic colon to a standard 1000 calorie mea...
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1983 |
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| Umfang: |
4 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: European journal of clinical pharmacology - 1968, 24(1983) vom: Juni, Seite 769-772 |
| Übergeordnetes Werk: |
volume:24 ; year:1983 ; month:06 ; pages:769-772 ; extent:4 |
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NLEJ202439860 |
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| 520 | |a Summary Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present investigation the motor response of the pelvic colon to a standard 1000 calorie meal was studied in 12 patients with the irritable bowel syndrome. The meal induced a significant increase in motor activity, lasting for 1 h and greatest in the first 30 min. In 6 cases the administration of sulpiride 100 mg i.m. significantly reduced the postprandial increase in colonic motor activity. Thus dopaminergic receptors may be involved in the colonic motor response to food. | ||
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(DE-627)NLEJ202439860 DE-627 ger DE-627 rakwb eng Inhibition of postprandial colonic motility by sulpiride in patients with irritable colon 1983 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present investigation the motor response of the pelvic colon to a standard 1000 calorie meal was studied in 12 patients with the irritable bowel syndrome. The meal induced a significant increase in motor activity, lasting for 1 h and greatest in the first 30 min. In 6 cases the administration of sulpiride 100 mg i.m. significantly reduced the postprandial increase in colonic motor activity. Thus dopaminergic receptors may be involved in the colonic motor response to food. Springer Online Journal Archives 1860-2002 Lanfranchi, G. A. oth Bazzocchi, G. oth Marzio, L. oth Campieri, M. oth Brignola, C. oth in European journal of clinical pharmacology 1968 24(1983) vom: Juni, Seite 769-772 (DE-627)NLEJ188986677 (DE-600)1459058-x 1432-1041 nnns volume:24 year:1983 month:06 pages:769-772 extent:4 http://dx.doi.org/10.1007/BF00607085 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 24 1983 6 769-772 4 |
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(DE-627)NLEJ202439860 DE-627 ger DE-627 rakwb eng Inhibition of postprandial colonic motility by sulpiride in patients with irritable colon 1983 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present investigation the motor response of the pelvic colon to a standard 1000 calorie meal was studied in 12 patients with the irritable bowel syndrome. The meal induced a significant increase in motor activity, lasting for 1 h and greatest in the first 30 min. In 6 cases the administration of sulpiride 100 mg i.m. significantly reduced the postprandial increase in colonic motor activity. Thus dopaminergic receptors may be involved in the colonic motor response to food. Springer Online Journal Archives 1860-2002 Lanfranchi, G. A. oth Bazzocchi, G. oth Marzio, L. oth Campieri, M. oth Brignola, C. oth in European journal of clinical pharmacology 1968 24(1983) vom: Juni, Seite 769-772 (DE-627)NLEJ188986677 (DE-600)1459058-x 1432-1041 nnns volume:24 year:1983 month:06 pages:769-772 extent:4 http://dx.doi.org/10.1007/BF00607085 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 24 1983 6 769-772 4 |
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(DE-627)NLEJ202439860 DE-627 ger DE-627 rakwb eng Inhibition of postprandial colonic motility by sulpiride in patients with irritable colon 1983 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present investigation the motor response of the pelvic colon to a standard 1000 calorie meal was studied in 12 patients with the irritable bowel syndrome. The meal induced a significant increase in motor activity, lasting for 1 h and greatest in the first 30 min. In 6 cases the administration of sulpiride 100 mg i.m. significantly reduced the postprandial increase in colonic motor activity. Thus dopaminergic receptors may be involved in the colonic motor response to food. Springer Online Journal Archives 1860-2002 Lanfranchi, G. A. oth Bazzocchi, G. oth Marzio, L. oth Campieri, M. oth Brignola, C. oth in European journal of clinical pharmacology 1968 24(1983) vom: Juni, Seite 769-772 (DE-627)NLEJ188986677 (DE-600)1459058-x 1432-1041 nnns volume:24 year:1983 month:06 pages:769-772 extent:4 http://dx.doi.org/10.1007/BF00607085 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 24 1983 6 769-772 4 |
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(DE-627)NLEJ202439860 DE-627 ger DE-627 rakwb eng Inhibition of postprandial colonic motility by sulpiride in patients with irritable colon 1983 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present investigation the motor response of the pelvic colon to a standard 1000 calorie meal was studied in 12 patients with the irritable bowel syndrome. The meal induced a significant increase in motor activity, lasting for 1 h and greatest in the first 30 min. In 6 cases the administration of sulpiride 100 mg i.m. significantly reduced the postprandial increase in colonic motor activity. Thus dopaminergic receptors may be involved in the colonic motor response to food. Springer Online Journal Archives 1860-2002 Lanfranchi, G. A. oth Bazzocchi, G. oth Marzio, L. oth Campieri, M. oth Brignola, C. oth in European journal of clinical pharmacology 1968 24(1983) vom: Juni, Seite 769-772 (DE-627)NLEJ188986677 (DE-600)1459058-x 1432-1041 nnns volume:24 year:1983 month:06 pages:769-772 extent:4 http://dx.doi.org/10.1007/BF00607085 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 24 1983 6 769-772 4 |
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(DE-627)NLEJ202439860 DE-627 ger DE-627 rakwb eng Inhibition of postprandial colonic motility by sulpiride in patients with irritable colon 1983 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present investigation the motor response of the pelvic colon to a standard 1000 calorie meal was studied in 12 patients with the irritable bowel syndrome. The meal induced a significant increase in motor activity, lasting for 1 h and greatest in the first 30 min. In 6 cases the administration of sulpiride 100 mg i.m. significantly reduced the postprandial increase in colonic motor activity. Thus dopaminergic receptors may be involved in the colonic motor response to food. Springer Online Journal Archives 1860-2002 Lanfranchi, G. A. oth Bazzocchi, G. oth Marzio, L. oth Campieri, M. oth Brignola, C. oth in European journal of clinical pharmacology 1968 24(1983) vom: Juni, Seite 769-772 (DE-627)NLEJ188986677 (DE-600)1459058-x 1432-1041 nnns volume:24 year:1983 month:06 pages:769-772 extent:4 http://dx.doi.org/10.1007/BF00607085 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 24 1983 6 769-772 4 |
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inhibition of postprandial colonic motility by sulpiride in patients with irritable colon |
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Inhibition of postprandial colonic motility by sulpiride in patients with irritable colon |
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Summary Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present investigation the motor response of the pelvic colon to a standard 1000 calorie meal was studied in 12 patients with the irritable bowel syndrome. The meal induced a significant increase in motor activity, lasting for 1 h and greatest in the first 30 min. In 6 cases the administration of sulpiride 100 mg i.m. significantly reduced the postprandial increase in colonic motor activity. Thus dopaminergic receptors may be involved in the colonic motor response to food. |
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Summary Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present investigation the motor response of the pelvic colon to a standard 1000 calorie meal was studied in 12 patients with the irritable bowel syndrome. The meal induced a significant increase in motor activity, lasting for 1 h and greatest in the first 30 min. In 6 cases the administration of sulpiride 100 mg i.m. significantly reduced the postprandial increase in colonic motor activity. Thus dopaminergic receptors may be involved in the colonic motor response to food. |
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Summary Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present investigation the motor response of the pelvic colon to a standard 1000 calorie meal was studied in 12 patients with the irritable bowel syndrome. The meal induced a significant increase in motor activity, lasting for 1 h and greatest in the first 30 min. In 6 cases the administration of sulpiride 100 mg i.m. significantly reduced the postprandial increase in colonic motor activity. Thus dopaminergic receptors may be involved in the colonic motor response to food. |
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