Quantitative aspect of two-factor analysis applied to radionuclide gated cardiac studies
Abstract The quantitative aspect of two factor analysis (TFA) applied to radionuclide gated cardiac studies was investigated using clinical data and a computer based simulation method. In the clinical investigation, the ejection fraction (EF) calculated from the extracted ventricular pattern (EVP) s...
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1988 |
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| Umfang: |
6 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
volume:14 ; year:1988 ; month:04 ; pages:190-195 ; extent:6 |
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NLEJ202804453 |
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| 520 | |a Abstract The quantitative aspect of two factor analysis (TFA) applied to radionuclide gated cardiac studies was investigated using clinical data and a computer based simulation method. In the clinical investigation, the ejection fraction (EF) calculated from the extracted ventricular pattern (EVP) significantly correlated with the left ventricular EF(LVEF) determined from multiple gated cardiac blood pool scans (MUGA), while the regression line deviated considerably from the line of identity. The contribution of the EVP(CEVP) to the total information inversely correlated significantly with the LVEF. In the computer simulation, a model simulating the atrial, ventricular, and background regions was studied. In the case with no statistical noise and constant background, the EF calculated from the EVP was nearly equal to the true EF, and the CEVP decreased as the EF increased. The statistical noise increased the EF and decreased the CEVP, this tendency was most marked when the true EF was less than about 50%. When background varied largely with time, the quantitative aspect deteriorated considerably. In conclusion, the clinical investigation results suggest that TFA has some possible use in quantitative analysis, however, the simulation results suggest that it should be used carefully because its quantitative aspect is affected by various factors. | ||
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(DE-627)NLEJ202804453 DE-627 ger DE-627 rakwb eng Quantitative aspect of two-factor analysis applied to radionuclide gated cardiac studies 1988 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract The quantitative aspect of two factor analysis (TFA) applied to radionuclide gated cardiac studies was investigated using clinical data and a computer based simulation method. In the clinical investigation, the ejection fraction (EF) calculated from the extracted ventricular pattern (EVP) significantly correlated with the left ventricular EF(LVEF) determined from multiple gated cardiac blood pool scans (MUGA), while the regression line deviated considerably from the line of identity. The contribution of the EVP(CEVP) to the total information inversely correlated significantly with the LVEF. In the computer simulation, a model simulating the atrial, ventricular, and background regions was studied. In the case with no statistical noise and constant background, the EF calculated from the EVP was nearly equal to the true EF, and the CEVP decreased as the EF increased. The statistical noise increased the EF and decreased the CEVP, this tendency was most marked when the true EF was less than about 50%. When background varied largely with time, the quantitative aspect deteriorated considerably. In conclusion, the clinical investigation results suggest that TFA has some possible use in quantitative analysis, however, the simulation results suggest that it should be used carefully because its quantitative aspect is affected by various factors. Springer Online Journal Archives 1860-2002 Murase, Kenya oth Mochizuki, Teruhito oth Hamamoto, Ken oth volume:14 year:1988 month:04 pages:190-195 extent:6 http://dx.doi.org/10.1007/BF00257326 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 14 1988 4 190-195 6 |
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(DE-627)NLEJ202804453 DE-627 ger DE-627 rakwb eng Quantitative aspect of two-factor analysis applied to radionuclide gated cardiac studies 1988 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract The quantitative aspect of two factor analysis (TFA) applied to radionuclide gated cardiac studies was investigated using clinical data and a computer based simulation method. In the clinical investigation, the ejection fraction (EF) calculated from the extracted ventricular pattern (EVP) significantly correlated with the left ventricular EF(LVEF) determined from multiple gated cardiac blood pool scans (MUGA), while the regression line deviated considerably from the line of identity. The contribution of the EVP(CEVP) to the total information inversely correlated significantly with the LVEF. In the computer simulation, a model simulating the atrial, ventricular, and background regions was studied. In the case with no statistical noise and constant background, the EF calculated from the EVP was nearly equal to the true EF, and the CEVP decreased as the EF increased. The statistical noise increased the EF and decreased the CEVP, this tendency was most marked when the true EF was less than about 50%. When background varied largely with time, the quantitative aspect deteriorated considerably. In conclusion, the clinical investigation results suggest that TFA has some possible use in quantitative analysis, however, the simulation results suggest that it should be used carefully because its quantitative aspect is affected by various factors. Springer Online Journal Archives 1860-2002 Murase, Kenya oth Mochizuki, Teruhito oth Hamamoto, Ken oth volume:14 year:1988 month:04 pages:190-195 extent:6 http://dx.doi.org/10.1007/BF00257326 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 14 1988 4 190-195 6 |
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(DE-627)NLEJ202804453 DE-627 ger DE-627 rakwb eng Quantitative aspect of two-factor analysis applied to radionuclide gated cardiac studies 1988 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract The quantitative aspect of two factor analysis (TFA) applied to radionuclide gated cardiac studies was investigated using clinical data and a computer based simulation method. In the clinical investigation, the ejection fraction (EF) calculated from the extracted ventricular pattern (EVP) significantly correlated with the left ventricular EF(LVEF) determined from multiple gated cardiac blood pool scans (MUGA), while the regression line deviated considerably from the line of identity. The contribution of the EVP(CEVP) to the total information inversely correlated significantly with the LVEF. In the computer simulation, a model simulating the atrial, ventricular, and background regions was studied. In the case with no statistical noise and constant background, the EF calculated from the EVP was nearly equal to the true EF, and the CEVP decreased as the EF increased. The statistical noise increased the EF and decreased the CEVP, this tendency was most marked when the true EF was less than about 50%. When background varied largely with time, the quantitative aspect deteriorated considerably. In conclusion, the clinical investigation results suggest that TFA has some possible use in quantitative analysis, however, the simulation results suggest that it should be used carefully because its quantitative aspect is affected by various factors. Springer Online Journal Archives 1860-2002 Murase, Kenya oth Mochizuki, Teruhito oth Hamamoto, Ken oth volume:14 year:1988 month:04 pages:190-195 extent:6 http://dx.doi.org/10.1007/BF00257326 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 14 1988 4 190-195 6 |
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(DE-627)NLEJ202804453 DE-627 ger DE-627 rakwb eng Quantitative aspect of two-factor analysis applied to radionuclide gated cardiac studies 1988 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract The quantitative aspect of two factor analysis (TFA) applied to radionuclide gated cardiac studies was investigated using clinical data and a computer based simulation method. In the clinical investigation, the ejection fraction (EF) calculated from the extracted ventricular pattern (EVP) significantly correlated with the left ventricular EF(LVEF) determined from multiple gated cardiac blood pool scans (MUGA), while the regression line deviated considerably from the line of identity. The contribution of the EVP(CEVP) to the total information inversely correlated significantly with the LVEF. In the computer simulation, a model simulating the atrial, ventricular, and background regions was studied. In the case with no statistical noise and constant background, the EF calculated from the EVP was nearly equal to the true EF, and the CEVP decreased as the EF increased. The statistical noise increased the EF and decreased the CEVP, this tendency was most marked when the true EF was less than about 50%. When background varied largely with time, the quantitative aspect deteriorated considerably. In conclusion, the clinical investigation results suggest that TFA has some possible use in quantitative analysis, however, the simulation results suggest that it should be used carefully because its quantitative aspect is affected by various factors. Springer Online Journal Archives 1860-2002 Murase, Kenya oth Mochizuki, Teruhito oth Hamamoto, Ken oth volume:14 year:1988 month:04 pages:190-195 extent:6 http://dx.doi.org/10.1007/BF00257326 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 14 1988 4 190-195 6 |
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(DE-627)NLEJ202804453 DE-627 ger DE-627 rakwb eng Quantitative aspect of two-factor analysis applied to radionuclide gated cardiac studies 1988 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract The quantitative aspect of two factor analysis (TFA) applied to radionuclide gated cardiac studies was investigated using clinical data and a computer based simulation method. In the clinical investigation, the ejection fraction (EF) calculated from the extracted ventricular pattern (EVP) significantly correlated with the left ventricular EF(LVEF) determined from multiple gated cardiac blood pool scans (MUGA), while the regression line deviated considerably from the line of identity. The contribution of the EVP(CEVP) to the total information inversely correlated significantly with the LVEF. In the computer simulation, a model simulating the atrial, ventricular, and background regions was studied. In the case with no statistical noise and constant background, the EF calculated from the EVP was nearly equal to the true EF, and the CEVP decreased as the EF increased. The statistical noise increased the EF and decreased the CEVP, this tendency was most marked when the true EF was less than about 50%. When background varied largely with time, the quantitative aspect deteriorated considerably. In conclusion, the clinical investigation results suggest that TFA has some possible use in quantitative analysis, however, the simulation results suggest that it should be used carefully because its quantitative aspect is affected by various factors. Springer Online Journal Archives 1860-2002 Murase, Kenya oth Mochizuki, Teruhito oth Hamamoto, Ken oth volume:14 year:1988 month:04 pages:190-195 extent:6 http://dx.doi.org/10.1007/BF00257326 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 14 1988 4 190-195 6 |
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Quantitative aspect of two-factor analysis applied to radionuclide gated cardiac studies |
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Abstract The quantitative aspect of two factor analysis (TFA) applied to radionuclide gated cardiac studies was investigated using clinical data and a computer based simulation method. In the clinical investigation, the ejection fraction (EF) calculated from the extracted ventricular pattern (EVP) significantly correlated with the left ventricular EF(LVEF) determined from multiple gated cardiac blood pool scans (MUGA), while the regression line deviated considerably from the line of identity. The contribution of the EVP(CEVP) to the total information inversely correlated significantly with the LVEF. In the computer simulation, a model simulating the atrial, ventricular, and background regions was studied. In the case with no statistical noise and constant background, the EF calculated from the EVP was nearly equal to the true EF, and the CEVP decreased as the EF increased. The statistical noise increased the EF and decreased the CEVP, this tendency was most marked when the true EF was less than about 50%. When background varied largely with time, the quantitative aspect deteriorated considerably. In conclusion, the clinical investigation results suggest that TFA has some possible use in quantitative analysis, however, the simulation results suggest that it should be used carefully because its quantitative aspect is affected by various factors. |
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Abstract The quantitative aspect of two factor analysis (TFA) applied to radionuclide gated cardiac studies was investigated using clinical data and a computer based simulation method. In the clinical investigation, the ejection fraction (EF) calculated from the extracted ventricular pattern (EVP) significantly correlated with the left ventricular EF(LVEF) determined from multiple gated cardiac blood pool scans (MUGA), while the regression line deviated considerably from the line of identity. The contribution of the EVP(CEVP) to the total information inversely correlated significantly with the LVEF. In the computer simulation, a model simulating the atrial, ventricular, and background regions was studied. In the case with no statistical noise and constant background, the EF calculated from the EVP was nearly equal to the true EF, and the CEVP decreased as the EF increased. The statistical noise increased the EF and decreased the CEVP, this tendency was most marked when the true EF was less than about 50%. When background varied largely with time, the quantitative aspect deteriorated considerably. In conclusion, the clinical investigation results suggest that TFA has some possible use in quantitative analysis, however, the simulation results suggest that it should be used carefully because its quantitative aspect is affected by various factors. |
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Abstract The quantitative aspect of two factor analysis (TFA) applied to radionuclide gated cardiac studies was investigated using clinical data and a computer based simulation method. In the clinical investigation, the ejection fraction (EF) calculated from the extracted ventricular pattern (EVP) significantly correlated with the left ventricular EF(LVEF) determined from multiple gated cardiac blood pool scans (MUGA), while the regression line deviated considerably from the line of identity. The contribution of the EVP(CEVP) to the total information inversely correlated significantly with the LVEF. In the computer simulation, a model simulating the atrial, ventricular, and background regions was studied. In the case with no statistical noise and constant background, the EF calculated from the EVP was nearly equal to the true EF, and the CEVP decreased as the EF increased. The statistical noise increased the EF and decreased the CEVP, this tendency was most marked when the true EF was less than about 50%. When background varied largely with time, the quantitative aspect deteriorated considerably. In conclusion, the clinical investigation results suggest that TFA has some possible use in quantitative analysis, however, the simulation results suggest that it should be used carefully because its quantitative aspect is affected by various factors. |
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