Long-term follow-up study of children with chronic ITP
Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as pe...
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Englisch |
| Erschienen: |
1989 |
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4 |
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Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: Annals of hematology - 1955, 59(1989) vom: Jan., Seite 105-108 |
| Übergeordnetes Werk: |
volume:59 ; year:1989 ; month:01 ; pages:105-108 ; extent:4 |
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| 520 | |a Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as petechiae, ecchymosis and epistaxis were still observed in about 22% – 28% of the patients with a period of morbidity ranging from 3 to 15 years after onset. Residual thrombocytopenia below 150,000/μl was found in 62% of patients within 5 years, 59% within 5 to 9 years and 57% within 10 – 14 years after onset. Other abnormalities were mild anemia, low serum level of IgA or IgM, positive antinuclear antibody, rheumatoid factor, and positive Coombs test in a small number of patients. Increased platelet-associated IgG was still obtained in patients with subnormal platelet counts whose morbid periods were 6 to 27 years after onset. Investigation of the patients by questionnaire revealed such complications as obesity, striae atrophicae, abdominal pain, headache, cataract, Perthes' disease, and cardiac complication in some patients. No apparent disturbances except for obesity were observed in their physical growth. | ||
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| 700 | 1 | |a Akatsuka, Jun-ichi |4 oth | |
| 700 | 1 | |a Fujisawa, Koji |4 oth | |
| 700 | 1 | |a Ishidoya, Naoko |4 oth | |
| 700 | 1 | |a Taguchi, Nobuyuki |4 oth | |
| 700 | 1 | |a Tsukimoto, Ichiro |4 oth | |
| 700 | 1 | |a Tsujino, Giichi |4 oth | |
| 700 | 1 | |a Nagao, Takeshi |4 oth | |
| 700 | 1 | |a Nakahata, Tatsutoshi |4 oth | |
| 700 | 1 | |a Miyazaki, Sumio |4 oth | |
| 700 | 1 | |a Takeda, Takeo |4 oth | |
| 700 | 1 | |a Akabane, Taro |4 oth | |
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(DE-627)NLEJ202966240 DE-627 ger DE-627 rakwb eng Long-term follow-up study of children with chronic ITP 1989 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as petechiae, ecchymosis and epistaxis were still observed in about 22% – 28% of the patients with a period of morbidity ranging from 3 to 15 years after onset. Residual thrombocytopenia below 150,000/μl was found in 62% of patients within 5 years, 59% within 5 to 9 years and 57% within 10 – 14 years after onset. Other abnormalities were mild anemia, low serum level of IgA or IgM, positive antinuclear antibody, rheumatoid factor, and positive Coombs test in a small number of patients. Increased platelet-associated IgG was still obtained in patients with subnormal platelet counts whose morbid periods were 6 to 27 years after onset. Investigation of the patients by questionnaire revealed such complications as obesity, striae atrophicae, abdominal pain, headache, cataract, Perthes' disease, and cardiac complication in some patients. No apparent disturbances except for obesity were observed in their physical growth. Springer Online Journal Archives 1860-2002 Akatsuka, Jun-ichi oth Fujisawa, Koji oth Ishidoya, Naoko oth Taguchi, Nobuyuki oth Tsukimoto, Ichiro oth Tsujino, Giichi oth Nagao, Takeshi oth Nakahata, Tatsutoshi oth Miyazaki, Sumio oth Takeda, Takeo oth Akabane, Taro oth in Annals of hematology 1955 59(1989) vom: Jan., Seite 105-108 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:59 year:1989 month:01 pages:105-108 extent:4 http://dx.doi.org/10.1007/BF00320258 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 59 1989 1 105-108 4 |
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(DE-627)NLEJ202966240 DE-627 ger DE-627 rakwb eng Long-term follow-up study of children with chronic ITP 1989 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as petechiae, ecchymosis and epistaxis were still observed in about 22% – 28% of the patients with a period of morbidity ranging from 3 to 15 years after onset. Residual thrombocytopenia below 150,000/μl was found in 62% of patients within 5 years, 59% within 5 to 9 years and 57% within 10 – 14 years after onset. Other abnormalities were mild anemia, low serum level of IgA or IgM, positive antinuclear antibody, rheumatoid factor, and positive Coombs test in a small number of patients. Increased platelet-associated IgG was still obtained in patients with subnormal platelet counts whose morbid periods were 6 to 27 years after onset. Investigation of the patients by questionnaire revealed such complications as obesity, striae atrophicae, abdominal pain, headache, cataract, Perthes' disease, and cardiac complication in some patients. No apparent disturbances except for obesity were observed in their physical growth. Springer Online Journal Archives 1860-2002 Akatsuka, Jun-ichi oth Fujisawa, Koji oth Ishidoya, Naoko oth Taguchi, Nobuyuki oth Tsukimoto, Ichiro oth Tsujino, Giichi oth Nagao, Takeshi oth Nakahata, Tatsutoshi oth Miyazaki, Sumio oth Takeda, Takeo oth Akabane, Taro oth in Annals of hematology 1955 59(1989) vom: Jan., Seite 105-108 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:59 year:1989 month:01 pages:105-108 extent:4 http://dx.doi.org/10.1007/BF00320258 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 59 1989 1 105-108 4 |
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(DE-627)NLEJ202966240 DE-627 ger DE-627 rakwb eng Long-term follow-up study of children with chronic ITP 1989 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as petechiae, ecchymosis and epistaxis were still observed in about 22% – 28% of the patients with a period of morbidity ranging from 3 to 15 years after onset. Residual thrombocytopenia below 150,000/μl was found in 62% of patients within 5 years, 59% within 5 to 9 years and 57% within 10 – 14 years after onset. Other abnormalities were mild anemia, low serum level of IgA or IgM, positive antinuclear antibody, rheumatoid factor, and positive Coombs test in a small number of patients. Increased platelet-associated IgG was still obtained in patients with subnormal platelet counts whose morbid periods were 6 to 27 years after onset. Investigation of the patients by questionnaire revealed such complications as obesity, striae atrophicae, abdominal pain, headache, cataract, Perthes' disease, and cardiac complication in some patients. No apparent disturbances except for obesity were observed in their physical growth. Springer Online Journal Archives 1860-2002 Akatsuka, Jun-ichi oth Fujisawa, Koji oth Ishidoya, Naoko oth Taguchi, Nobuyuki oth Tsukimoto, Ichiro oth Tsujino, Giichi oth Nagao, Takeshi oth Nakahata, Tatsutoshi oth Miyazaki, Sumio oth Takeda, Takeo oth Akabane, Taro oth in Annals of hematology 1955 59(1989) vom: Jan., Seite 105-108 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:59 year:1989 month:01 pages:105-108 extent:4 http://dx.doi.org/10.1007/BF00320258 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 59 1989 1 105-108 4 |
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(DE-627)NLEJ202966240 DE-627 ger DE-627 rakwb eng Long-term follow-up study of children with chronic ITP 1989 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as petechiae, ecchymosis and epistaxis were still observed in about 22% – 28% of the patients with a period of morbidity ranging from 3 to 15 years after onset. Residual thrombocytopenia below 150,000/μl was found in 62% of patients within 5 years, 59% within 5 to 9 years and 57% within 10 – 14 years after onset. Other abnormalities were mild anemia, low serum level of IgA or IgM, positive antinuclear antibody, rheumatoid factor, and positive Coombs test in a small number of patients. Increased platelet-associated IgG was still obtained in patients with subnormal platelet counts whose morbid periods were 6 to 27 years after onset. Investigation of the patients by questionnaire revealed such complications as obesity, striae atrophicae, abdominal pain, headache, cataract, Perthes' disease, and cardiac complication in some patients. No apparent disturbances except for obesity were observed in their physical growth. Springer Online Journal Archives 1860-2002 Akatsuka, Jun-ichi oth Fujisawa, Koji oth Ishidoya, Naoko oth Taguchi, Nobuyuki oth Tsukimoto, Ichiro oth Tsujino, Giichi oth Nagao, Takeshi oth Nakahata, Tatsutoshi oth Miyazaki, Sumio oth Takeda, Takeo oth Akabane, Taro oth in Annals of hematology 1955 59(1989) vom: Jan., Seite 105-108 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:59 year:1989 month:01 pages:105-108 extent:4 http://dx.doi.org/10.1007/BF00320258 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 59 1989 1 105-108 4 |
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(DE-627)NLEJ202966240 DE-627 ger DE-627 rakwb eng Long-term follow-up study of children with chronic ITP 1989 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as petechiae, ecchymosis and epistaxis were still observed in about 22% – 28% of the patients with a period of morbidity ranging from 3 to 15 years after onset. Residual thrombocytopenia below 150,000/μl was found in 62% of patients within 5 years, 59% within 5 to 9 years and 57% within 10 – 14 years after onset. Other abnormalities were mild anemia, low serum level of IgA or IgM, positive antinuclear antibody, rheumatoid factor, and positive Coombs test in a small number of patients. Increased platelet-associated IgG was still obtained in patients with subnormal platelet counts whose morbid periods were 6 to 27 years after onset. Investigation of the patients by questionnaire revealed such complications as obesity, striae atrophicae, abdominal pain, headache, cataract, Perthes' disease, and cardiac complication in some patients. No apparent disturbances except for obesity were observed in their physical growth. Springer Online Journal Archives 1860-2002 Akatsuka, Jun-ichi oth Fujisawa, Koji oth Ishidoya, Naoko oth Taguchi, Nobuyuki oth Tsukimoto, Ichiro oth Tsujino, Giichi oth Nagao, Takeshi oth Nakahata, Tatsutoshi oth Miyazaki, Sumio oth Takeda, Takeo oth Akabane, Taro oth in Annals of hematology 1955 59(1989) vom: Jan., Seite 105-108 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:59 year:1989 month:01 pages:105-108 extent:4 http://dx.doi.org/10.1007/BF00320258 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 59 1989 1 105-108 4 |
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Long-term follow-up study of children with chronic ITP |
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Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as petechiae, ecchymosis and epistaxis were still observed in about 22% – 28% of the patients with a period of morbidity ranging from 3 to 15 years after onset. Residual thrombocytopenia below 150,000/μl was found in 62% of patients within 5 years, 59% within 5 to 9 years and 57% within 10 – 14 years after onset. Other abnormalities were mild anemia, low serum level of IgA or IgM, positive antinuclear antibody, rheumatoid factor, and positive Coombs test in a small number of patients. Increased platelet-associated IgG was still obtained in patients with subnormal platelet counts whose morbid periods were 6 to 27 years after onset. Investigation of the patients by questionnaire revealed such complications as obesity, striae atrophicae, abdominal pain, headache, cataract, Perthes' disease, and cardiac complication in some patients. No apparent disturbances except for obesity were observed in their physical growth. |
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Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as petechiae, ecchymosis and epistaxis were still observed in about 22% – 28% of the patients with a period of morbidity ranging from 3 to 15 years after onset. Residual thrombocytopenia below 150,000/μl was found in 62% of patients within 5 years, 59% within 5 to 9 years and 57% within 10 – 14 years after onset. Other abnormalities were mild anemia, low serum level of IgA or IgM, positive antinuclear antibody, rheumatoid factor, and positive Coombs test in a small number of patients. Increased platelet-associated IgG was still obtained in patients with subnormal platelet counts whose morbid periods were 6 to 27 years after onset. Investigation of the patients by questionnaire revealed such complications as obesity, striae atrophicae, abdominal pain, headache, cataract, Perthes' disease, and cardiac complication in some patients. No apparent disturbances except for obesity were observed in their physical growth. |
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Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as petechiae, ecchymosis and epistaxis were still observed in about 22% – 28% of the patients with a period of morbidity ranging from 3 to 15 years after onset. Residual thrombocytopenia below 150,000/μl was found in 62% of patients within 5 years, 59% within 5 to 9 years and 57% within 10 – 14 years after onset. Other abnormalities were mild anemia, low serum level of IgA or IgM, positive antinuclear antibody, rheumatoid factor, and positive Coombs test in a small number of patients. Increased platelet-associated IgG was still obtained in patients with subnormal platelet counts whose morbid periods were 6 to 27 years after onset. Investigation of the patients by questionnaire revealed such complications as obesity, striae atrophicae, abdominal pain, headache, cataract, Perthes' disease, and cardiac complication in some patients. No apparent disturbances except for obesity were observed in their physical growth. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ202966240</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230505233623.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070528s1989 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ202966240</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Long-term follow-up study of children with chronic ITP</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1989</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">4</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Summary A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologic abnormalities, complications and physical growth. Such hemorrhagic symptoms as petechiae, ecchymosis and epistaxis were still observed in about 22% – 28% of the patients with a period of morbidity ranging from 3 to 15 years after onset. Residual thrombocytopenia below 150,000/μl was found in 62% of patients within 5 years, 59% within 5 to 9 years and 57% within 10 – 14 years after onset. Other abnormalities were mild anemia, low serum level of IgA or IgM, positive antinuclear antibody, rheumatoid factor, and positive Coombs test in a small number of patients. Increased platelet-associated IgG was still obtained in patients with subnormal platelet counts whose morbid periods were 6 to 27 years after onset. Investigation of the patients by questionnaire revealed such complications as obesity, striae atrophicae, abdominal pain, headache, cataract, Perthes' disease, and cardiac complication in some patients. No apparent disturbances except for obesity were observed in their physical growth.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Springer Online Journal Archives 1860-2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Akatsuka, Jun-ichi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Fujisawa, Koji</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ishidoya, Naoko</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Taguchi, Nobuyuki</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tsukimoto, Ichiro</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tsujino, Giichi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nagao, Takeshi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nakahata, Tatsutoshi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Miyazaki, Sumio</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Takeda, Takeo</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Akabane, Taro</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Annals of hematology</subfield><subfield code="d">1955</subfield><subfield code="g">59(1989) vom: Jan., Seite 105-108</subfield><subfield code="w">(DE-627)NLEJ18898836X</subfield><subfield code="w">(DE-600)1458429-3</subfield><subfield code="x">1432-0584</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:59</subfield><subfield code="g">year:1989</subfield><subfield code="g">month:01</subfield><subfield code="g">pages:105-108</subfield><subfield code="g">extent:4</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1007/BF00320258</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SOJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">59</subfield><subfield code="j">1989</subfield><subfield code="c">1</subfield><subfield code="h">105-108</subfield><subfield code="g">4</subfield></datafield></record></collection>
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