Stimulation of growth of human malignant lymphoma and lymphoid leukemia cells in vitro
Summary We have analyzed cultures of malignant lymphoma cells and cells from patients with acute lymphoid leukemia in methylcellulose for their ability to from colonies. Clonogenic growth was examined in the presence or absence of fetal calf serum (FCS), platelet-poor plasma (PPP), medium conditione...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1992 |
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| Umfang: |
6 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: Annals of hematology - 1955, 64(1992) vom: Feb., Seite 66-71 |
| Übergeordnetes Werk: |
volume:64 ; year:1992 ; month:02 ; pages:66-71 ; extent:6 |
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NLEJ202970256 |
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| 520 | |a Summary We have analyzed cultures of malignant lymphoma cells and cells from patients with acute lymphoid leukemia in methylcellulose for their ability to from colonies. Clonogenic growth was examined in the presence or absence of fetal calf serum (FCS), platelet-poor plasma (PPP), medium conditioned by phytohemagglutininstimulated leukocytes (PHA-LCM), or irradiated allogeneic bone marrow stroma cells. Cells from 25 lymphoma patients — 17 with non-Hodgkin's lymphoma (NHL), eight with Hodgkin's disease (HD) — and from 19 patients with acute lymphocytic leukemia (ALL) were investigated. We show that colony growth can be obtained in a minority of cases (in 3 NHL, 5 HD, and 2 ALL) and that the use of FCS and allogeneic irradiated stroma cells may be required for optimal colony formation. | ||
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| 700 | 1 | |a Strobel, E. -S. |4 oth | |
| 700 | 1 | |a Bross, K. J. |4 oth | |
| 700 | 1 | |a Mertelsmann, R. |4 oth | |
| 700 | 1 | |a Herrmann, F. |4 oth | |
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(DE-627)NLEJ202970256 DE-627 ger DE-627 rakwb eng Stimulation of growth of human malignant lymphoma and lymphoid leukemia cells in vitro 1992 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary We have analyzed cultures of malignant lymphoma cells and cells from patients with acute lymphoid leukemia in methylcellulose for their ability to from colonies. Clonogenic growth was examined in the presence or absence of fetal calf serum (FCS), platelet-poor plasma (PPP), medium conditioned by phytohemagglutininstimulated leukocytes (PHA-LCM), or irradiated allogeneic bone marrow stroma cells. Cells from 25 lymphoma patients — 17 with non-Hodgkin's lymphoma (NHL), eight with Hodgkin's disease (HD) — and from 19 patients with acute lymphocytic leukemia (ALL) were investigated. We show that colony growth can be obtained in a minority of cases (in 3 NHL, 5 HD, and 2 ALL) and that the use of FCS and allogeneic irradiated stroma cells may be required for optimal colony formation. Springer Online Journal Archives 1860-2002 Strobel, E. -S. oth Bross, K. J. oth Mertelsmann, R. oth Herrmann, F. oth in Annals of hematology 1955 64(1992) vom: Feb., Seite 66-71 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:64 year:1992 month:02 pages:66-71 extent:6 http://dx.doi.org/10.1007/BF01715347 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 64 1992 2 66-71 6 |
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(DE-627)NLEJ202970256 DE-627 ger DE-627 rakwb eng Stimulation of growth of human malignant lymphoma and lymphoid leukemia cells in vitro 1992 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary We have analyzed cultures of malignant lymphoma cells and cells from patients with acute lymphoid leukemia in methylcellulose for their ability to from colonies. Clonogenic growth was examined in the presence or absence of fetal calf serum (FCS), platelet-poor plasma (PPP), medium conditioned by phytohemagglutininstimulated leukocytes (PHA-LCM), or irradiated allogeneic bone marrow stroma cells. Cells from 25 lymphoma patients — 17 with non-Hodgkin's lymphoma (NHL), eight with Hodgkin's disease (HD) — and from 19 patients with acute lymphocytic leukemia (ALL) were investigated. We show that colony growth can be obtained in a minority of cases (in 3 NHL, 5 HD, and 2 ALL) and that the use of FCS and allogeneic irradiated stroma cells may be required for optimal colony formation. Springer Online Journal Archives 1860-2002 Strobel, E. -S. oth Bross, K. J. oth Mertelsmann, R. oth Herrmann, F. oth in Annals of hematology 1955 64(1992) vom: Feb., Seite 66-71 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:64 year:1992 month:02 pages:66-71 extent:6 http://dx.doi.org/10.1007/BF01715347 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 64 1992 2 66-71 6 |
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(DE-627)NLEJ202970256 DE-627 ger DE-627 rakwb eng Stimulation of growth of human malignant lymphoma and lymphoid leukemia cells in vitro 1992 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary We have analyzed cultures of malignant lymphoma cells and cells from patients with acute lymphoid leukemia in methylcellulose for their ability to from colonies. Clonogenic growth was examined in the presence or absence of fetal calf serum (FCS), platelet-poor plasma (PPP), medium conditioned by phytohemagglutininstimulated leukocytes (PHA-LCM), or irradiated allogeneic bone marrow stroma cells. Cells from 25 lymphoma patients — 17 with non-Hodgkin's lymphoma (NHL), eight with Hodgkin's disease (HD) — and from 19 patients with acute lymphocytic leukemia (ALL) were investigated. We show that colony growth can be obtained in a minority of cases (in 3 NHL, 5 HD, and 2 ALL) and that the use of FCS and allogeneic irradiated stroma cells may be required for optimal colony formation. Springer Online Journal Archives 1860-2002 Strobel, E. -S. oth Bross, K. J. oth Mertelsmann, R. oth Herrmann, F. oth in Annals of hematology 1955 64(1992) vom: Feb., Seite 66-71 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:64 year:1992 month:02 pages:66-71 extent:6 http://dx.doi.org/10.1007/BF01715347 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 64 1992 2 66-71 6 |
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(DE-627)NLEJ202970256 DE-627 ger DE-627 rakwb eng Stimulation of growth of human malignant lymphoma and lymphoid leukemia cells in vitro 1992 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary We have analyzed cultures of malignant lymphoma cells and cells from patients with acute lymphoid leukemia in methylcellulose for their ability to from colonies. Clonogenic growth was examined in the presence or absence of fetal calf serum (FCS), platelet-poor plasma (PPP), medium conditioned by phytohemagglutininstimulated leukocytes (PHA-LCM), or irradiated allogeneic bone marrow stroma cells. Cells from 25 lymphoma patients — 17 with non-Hodgkin's lymphoma (NHL), eight with Hodgkin's disease (HD) — and from 19 patients with acute lymphocytic leukemia (ALL) were investigated. We show that colony growth can be obtained in a minority of cases (in 3 NHL, 5 HD, and 2 ALL) and that the use of FCS and allogeneic irradiated stroma cells may be required for optimal colony formation. Springer Online Journal Archives 1860-2002 Strobel, E. -S. oth Bross, K. J. oth Mertelsmann, R. oth Herrmann, F. oth in Annals of hematology 1955 64(1992) vom: Feb., Seite 66-71 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:64 year:1992 month:02 pages:66-71 extent:6 http://dx.doi.org/10.1007/BF01715347 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 64 1992 2 66-71 6 |
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(DE-627)NLEJ202970256 DE-627 ger DE-627 rakwb eng Stimulation of growth of human malignant lymphoma and lymphoid leukemia cells in vitro 1992 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary We have analyzed cultures of malignant lymphoma cells and cells from patients with acute lymphoid leukemia in methylcellulose for their ability to from colonies. Clonogenic growth was examined in the presence or absence of fetal calf serum (FCS), platelet-poor plasma (PPP), medium conditioned by phytohemagglutininstimulated leukocytes (PHA-LCM), or irradiated allogeneic bone marrow stroma cells. Cells from 25 lymphoma patients — 17 with non-Hodgkin's lymphoma (NHL), eight with Hodgkin's disease (HD) — and from 19 patients with acute lymphocytic leukemia (ALL) were investigated. We show that colony growth can be obtained in a minority of cases (in 3 NHL, 5 HD, and 2 ALL) and that the use of FCS and allogeneic irradiated stroma cells may be required for optimal colony formation. Springer Online Journal Archives 1860-2002 Strobel, E. -S. oth Bross, K. J. oth Mertelsmann, R. oth Herrmann, F. oth in Annals of hematology 1955 64(1992) vom: Feb., Seite 66-71 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:64 year:1992 month:02 pages:66-71 extent:6 http://dx.doi.org/10.1007/BF01715347 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 64 1992 2 66-71 6 |
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stimulation of growth of human malignant lymphoma and lymphoid leukemia cells in vitro |
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Stimulation of growth of human malignant lymphoma and lymphoid leukemia cells in vitro |
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Summary We have analyzed cultures of malignant lymphoma cells and cells from patients with acute lymphoid leukemia in methylcellulose for their ability to from colonies. Clonogenic growth was examined in the presence or absence of fetal calf serum (FCS), platelet-poor plasma (PPP), medium conditioned by phytohemagglutininstimulated leukocytes (PHA-LCM), or irradiated allogeneic bone marrow stroma cells. Cells from 25 lymphoma patients — 17 with non-Hodgkin's lymphoma (NHL), eight with Hodgkin's disease (HD) — and from 19 patients with acute lymphocytic leukemia (ALL) were investigated. We show that colony growth can be obtained in a minority of cases (in 3 NHL, 5 HD, and 2 ALL) and that the use of FCS and allogeneic irradiated stroma cells may be required for optimal colony formation. |
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Summary We have analyzed cultures of malignant lymphoma cells and cells from patients with acute lymphoid leukemia in methylcellulose for their ability to from colonies. Clonogenic growth was examined in the presence or absence of fetal calf serum (FCS), platelet-poor plasma (PPP), medium conditioned by phytohemagglutininstimulated leukocytes (PHA-LCM), or irradiated allogeneic bone marrow stroma cells. Cells from 25 lymphoma patients — 17 with non-Hodgkin's lymphoma (NHL), eight with Hodgkin's disease (HD) — and from 19 patients with acute lymphocytic leukemia (ALL) were investigated. We show that colony growth can be obtained in a minority of cases (in 3 NHL, 5 HD, and 2 ALL) and that the use of FCS and allogeneic irradiated stroma cells may be required for optimal colony formation. |
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Summary We have analyzed cultures of malignant lymphoma cells and cells from patients with acute lymphoid leukemia in methylcellulose for their ability to from colonies. Clonogenic growth was examined in the presence or absence of fetal calf serum (FCS), platelet-poor plasma (PPP), medium conditioned by phytohemagglutininstimulated leukocytes (PHA-LCM), or irradiated allogeneic bone marrow stroma cells. Cells from 25 lymphoma patients — 17 with non-Hodgkin's lymphoma (NHL), eight with Hodgkin's disease (HD) — and from 19 patients with acute lymphocytic leukemia (ALL) were investigated. We show that colony growth can be obtained in a minority of cases (in 3 NHL, 5 HD, and 2 ALL) and that the use of FCS and allogeneic irradiated stroma cells may be required for optimal colony formation. |
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