Transient lupus anticoagulant associated with hypoprothrombinemia and Factor XII deficiency following adenovirus infection
Summary A potent lupus anticoagulant (LA) was detected in four children, 1 week after the clinical onset of an adenovirus infection. The adenovirus infection was documented by direct virus detection in the stool of one patient and serologically in the others. None of the children had elevated titers...
Ausführliche Beschreibung
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Englisch |
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1993 |
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5 |
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Springer Online Journal Archives 1860-2002 |
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in: Annals of hematology - 1955, 67(1993) vom: Feb., Seite 95-99 |
Übergeordnetes Werk: |
volume:67 ; year:1993 ; month:02 ; pages:95-99 ; extent:5 |
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NLEJ202972372 |
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245 | 1 | 0 | |a Transient lupus anticoagulant associated with hypoprothrombinemia and Factor XII deficiency following adenovirus infection |
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520 | |a Summary A potent lupus anticoagulant (LA) was detected in four children, 1 week after the clinical onset of an adenovirus infection. The adenovirus infection was documented by direct virus detection in the stool of one patient and serologically in the others. None of the children had elevated titers of IgM- and only one of IgG-anticardiolipin antibodies (ACA). All patients had a marked reduction of prothrombin activity as well as antigen. Prothrombin-antibody complexes were demonstrated in the patients' plasma or mixtures of patient and normal plasma. Factor XII activity was moderately reduced in three of the patients. All coagulation abnormalities returned to normal within 4–12 weeks. Localized bleeding was observed in two cases, but there was no generalized bleeding tendency or evidence of thrombosis. | ||
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700 | 1 | |a Jaeger, U. |4 oth | |
700 | 1 | |a Kapiotis, S. |4 oth | |
700 | 1 | |a Pabinger, I. |4 oth | |
700 | 1 | |a Puchhammer, E. |4 oth | |
700 | 1 | |a Kyrle, P. A. |4 oth | |
700 | 1 | |a Lechner, K. |4 oth | |
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(DE-627)NLEJ202972372 DE-627 ger DE-627 rakwb eng Transient lupus anticoagulant associated with hypoprothrombinemia and Factor XII deficiency following adenovirus infection 1993 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A potent lupus anticoagulant (LA) was detected in four children, 1 week after the clinical onset of an adenovirus infection. The adenovirus infection was documented by direct virus detection in the stool of one patient and serologically in the others. None of the children had elevated titers of IgM- and only one of IgG-anticardiolipin antibodies (ACA). All patients had a marked reduction of prothrombin activity as well as antigen. Prothrombin-antibody complexes were demonstrated in the patients' plasma or mixtures of patient and normal plasma. Factor XII activity was moderately reduced in three of the patients. All coagulation abnormalities returned to normal within 4–12 weeks. Localized bleeding was observed in two cases, but there was no generalized bleeding tendency or evidence of thrombosis. Springer Online Journal Archives 1860-2002 Jaeger, U. oth Kapiotis, S. oth Pabinger, I. oth Puchhammer, E. oth Kyrle, P. A. oth Lechner, K. oth in Annals of hematology 1955 67(1993) vom: Feb., Seite 95-99 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:67 year:1993 month:02 pages:95-99 extent:5 http://dx.doi.org/10.1007/BF01788133 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 67 1993 2 95-99 5 |
spelling |
(DE-627)NLEJ202972372 DE-627 ger DE-627 rakwb eng Transient lupus anticoagulant associated with hypoprothrombinemia and Factor XII deficiency following adenovirus infection 1993 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A potent lupus anticoagulant (LA) was detected in four children, 1 week after the clinical onset of an adenovirus infection. The adenovirus infection was documented by direct virus detection in the stool of one patient and serologically in the others. None of the children had elevated titers of IgM- and only one of IgG-anticardiolipin antibodies (ACA). All patients had a marked reduction of prothrombin activity as well as antigen. Prothrombin-antibody complexes were demonstrated in the patients' plasma or mixtures of patient and normal plasma. Factor XII activity was moderately reduced in three of the patients. All coagulation abnormalities returned to normal within 4–12 weeks. Localized bleeding was observed in two cases, but there was no generalized bleeding tendency or evidence of thrombosis. Springer Online Journal Archives 1860-2002 Jaeger, U. oth Kapiotis, S. oth Pabinger, I. oth Puchhammer, E. oth Kyrle, P. A. oth Lechner, K. oth in Annals of hematology 1955 67(1993) vom: Feb., Seite 95-99 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:67 year:1993 month:02 pages:95-99 extent:5 http://dx.doi.org/10.1007/BF01788133 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 67 1993 2 95-99 5 |
allfields_unstemmed |
(DE-627)NLEJ202972372 DE-627 ger DE-627 rakwb eng Transient lupus anticoagulant associated with hypoprothrombinemia and Factor XII deficiency following adenovirus infection 1993 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A potent lupus anticoagulant (LA) was detected in four children, 1 week after the clinical onset of an adenovirus infection. The adenovirus infection was documented by direct virus detection in the stool of one patient and serologically in the others. None of the children had elevated titers of IgM- and only one of IgG-anticardiolipin antibodies (ACA). All patients had a marked reduction of prothrombin activity as well as antigen. Prothrombin-antibody complexes were demonstrated in the patients' plasma or mixtures of patient and normal plasma. Factor XII activity was moderately reduced in three of the patients. All coagulation abnormalities returned to normal within 4–12 weeks. Localized bleeding was observed in two cases, but there was no generalized bleeding tendency or evidence of thrombosis. Springer Online Journal Archives 1860-2002 Jaeger, U. oth Kapiotis, S. oth Pabinger, I. oth Puchhammer, E. oth Kyrle, P. A. oth Lechner, K. oth in Annals of hematology 1955 67(1993) vom: Feb., Seite 95-99 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:67 year:1993 month:02 pages:95-99 extent:5 http://dx.doi.org/10.1007/BF01788133 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 67 1993 2 95-99 5 |
allfieldsGer |
(DE-627)NLEJ202972372 DE-627 ger DE-627 rakwb eng Transient lupus anticoagulant associated with hypoprothrombinemia and Factor XII deficiency following adenovirus infection 1993 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A potent lupus anticoagulant (LA) was detected in four children, 1 week after the clinical onset of an adenovirus infection. The adenovirus infection was documented by direct virus detection in the stool of one patient and serologically in the others. None of the children had elevated titers of IgM- and only one of IgG-anticardiolipin antibodies (ACA). All patients had a marked reduction of prothrombin activity as well as antigen. Prothrombin-antibody complexes were demonstrated in the patients' plasma or mixtures of patient and normal plasma. Factor XII activity was moderately reduced in three of the patients. All coagulation abnormalities returned to normal within 4–12 weeks. Localized bleeding was observed in two cases, but there was no generalized bleeding tendency or evidence of thrombosis. Springer Online Journal Archives 1860-2002 Jaeger, U. oth Kapiotis, S. oth Pabinger, I. oth Puchhammer, E. oth Kyrle, P. A. oth Lechner, K. oth in Annals of hematology 1955 67(1993) vom: Feb., Seite 95-99 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:67 year:1993 month:02 pages:95-99 extent:5 http://dx.doi.org/10.1007/BF01788133 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 67 1993 2 95-99 5 |
allfieldsSound |
(DE-627)NLEJ202972372 DE-627 ger DE-627 rakwb eng Transient lupus anticoagulant associated with hypoprothrombinemia and Factor XII deficiency following adenovirus infection 1993 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A potent lupus anticoagulant (LA) was detected in four children, 1 week after the clinical onset of an adenovirus infection. The adenovirus infection was documented by direct virus detection in the stool of one patient and serologically in the others. None of the children had elevated titers of IgM- and only one of IgG-anticardiolipin antibodies (ACA). All patients had a marked reduction of prothrombin activity as well as antigen. Prothrombin-antibody complexes were demonstrated in the patients' plasma or mixtures of patient and normal plasma. Factor XII activity was moderately reduced in three of the patients. All coagulation abnormalities returned to normal within 4–12 weeks. Localized bleeding was observed in two cases, but there was no generalized bleeding tendency or evidence of thrombosis. Springer Online Journal Archives 1860-2002 Jaeger, U. oth Kapiotis, S. oth Pabinger, I. oth Puchhammer, E. oth Kyrle, P. A. oth Lechner, K. oth in Annals of hematology 1955 67(1993) vom: Feb., Seite 95-99 (DE-627)NLEJ18898836X (DE-600)1458429-3 1432-0584 nnns volume:67 year:1993 month:02 pages:95-99 extent:5 http://dx.doi.org/10.1007/BF01788133 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 67 1993 2 95-99 5 |
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transient lupus anticoagulant associated with hypoprothrombinemia and factor xii deficiency following adenovirus infection |
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Transient lupus anticoagulant associated with hypoprothrombinemia and Factor XII deficiency following adenovirus infection |
abstract |
Summary A potent lupus anticoagulant (LA) was detected in four children, 1 week after the clinical onset of an adenovirus infection. The adenovirus infection was documented by direct virus detection in the stool of one patient and serologically in the others. None of the children had elevated titers of IgM- and only one of IgG-anticardiolipin antibodies (ACA). All patients had a marked reduction of prothrombin activity as well as antigen. Prothrombin-antibody complexes were demonstrated in the patients' plasma or mixtures of patient and normal plasma. Factor XII activity was moderately reduced in three of the patients. All coagulation abnormalities returned to normal within 4–12 weeks. Localized bleeding was observed in two cases, but there was no generalized bleeding tendency or evidence of thrombosis. |
abstractGer |
Summary A potent lupus anticoagulant (LA) was detected in four children, 1 week after the clinical onset of an adenovirus infection. The adenovirus infection was documented by direct virus detection in the stool of one patient and serologically in the others. None of the children had elevated titers of IgM- and only one of IgG-anticardiolipin antibodies (ACA). All patients had a marked reduction of prothrombin activity as well as antigen. Prothrombin-antibody complexes were demonstrated in the patients' plasma or mixtures of patient and normal plasma. Factor XII activity was moderately reduced in three of the patients. All coagulation abnormalities returned to normal within 4–12 weeks. Localized bleeding was observed in two cases, but there was no generalized bleeding tendency or evidence of thrombosis. |
abstract_unstemmed |
Summary A potent lupus anticoagulant (LA) was detected in four children, 1 week after the clinical onset of an adenovirus infection. The adenovirus infection was documented by direct virus detection in the stool of one patient and serologically in the others. None of the children had elevated titers of IgM- and only one of IgG-anticardiolipin antibodies (ACA). All patients had a marked reduction of prothrombin activity as well as antigen. Prothrombin-antibody complexes were demonstrated in the patients' plasma or mixtures of patient and normal plasma. Factor XII activity was moderately reduced in three of the patients. All coagulation abnormalities returned to normal within 4–12 weeks. Localized bleeding was observed in two cases, but there was no generalized bleeding tendency or evidence of thrombosis. |
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Transient lupus anticoagulant associated with hypoprothrombinemia and Factor XII deficiency following adenovirus infection |
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