Acute presentation of Tangier polyneuropathy: a clinical and morphological study
Summary We describe a patient with Tangier disease and a peripheral neuropathy with an unusual acute onset. The morphological studies of sural nerve biopsy revealed both axonal degeneration and demyelination, and the fiber loss was preferentially restricted to two of ten nerve fascicles. The cytopla...
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1993 |
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| Umfang: |
5 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: Acta neuropathologica - 1961, 86(1993) vom: Jan., Seite 90-94 |
| Übergeordnetes Werk: |
volume:86 ; year:1993 ; month:01 ; pages:90-94 ; extent:5 |
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NLEJ203609379 |
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| 245 | 1 | 0 | |a Acute presentation of Tangier polyneuropathy: a clinical and morphological study |
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| 520 | |a Summary We describe a patient with Tangier disease and a peripheral neuropathy with an unusual acute onset. The morphological studies of sural nerve biopsy revealed both axonal degeneration and demyelination, and the fiber loss was preferentially restricted to two of ten nerve fascicles. The cytoplasm of Schwann cells, fibroblasts, macrophages and pericytes were vacuolated because of the presence of numerous lipid droplets. The clinical and morphological findings are consistent with the possibility that ischemia plays a major role in causing this neuropathy. | ||
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| 700 | 1 | |a Ruotolo, Giacomo |4 oth | |
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(DE-627)NLEJ203609379 DE-627 ger DE-627 rakwb eng Acute presentation of Tangier polyneuropathy: a clinical and morphological study 1993 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary We describe a patient with Tangier disease and a peripheral neuropathy with an unusual acute onset. The morphological studies of sural nerve biopsy revealed both axonal degeneration and demyelination, and the fiber loss was preferentially restricted to two of ten nerve fascicles. The cytoplasm of Schwann cells, fibroblasts, macrophages and pericytes were vacuolated because of the presence of numerous lipid droplets. The clinical and morphological findings are consistent with the possibility that ischemia plays a major role in causing this neuropathy. Springer Online Journal Archives 1860-2002 Fazio, Raffaella oth Nemni, Raffaello oth Quattrini, Angelo oth Ruotolo, Giacomo oth Iannaccone, Sandro oth Mamoli, Daniela oth Lodi, Monica oth Canal, Nicola oth in Acta neuropathologica 1961 86(1993) vom: Jan., Seite 90-94 (DE-627)NLEJ188990917 (DE-600)1458410-4 1432-0533 nnns volume:86 year:1993 month:01 pages:90-94 extent:5 http://dx.doi.org/10.1007/BF00454905 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 86 1993 1 90-94 5 |
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(DE-627)NLEJ203609379 DE-627 ger DE-627 rakwb eng Acute presentation of Tangier polyneuropathy: a clinical and morphological study 1993 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary We describe a patient with Tangier disease and a peripheral neuropathy with an unusual acute onset. The morphological studies of sural nerve biopsy revealed both axonal degeneration and demyelination, and the fiber loss was preferentially restricted to two of ten nerve fascicles. The cytoplasm of Schwann cells, fibroblasts, macrophages and pericytes were vacuolated because of the presence of numerous lipid droplets. The clinical and morphological findings are consistent with the possibility that ischemia plays a major role in causing this neuropathy. Springer Online Journal Archives 1860-2002 Fazio, Raffaella oth Nemni, Raffaello oth Quattrini, Angelo oth Ruotolo, Giacomo oth Iannaccone, Sandro oth Mamoli, Daniela oth Lodi, Monica oth Canal, Nicola oth in Acta neuropathologica 1961 86(1993) vom: Jan., Seite 90-94 (DE-627)NLEJ188990917 (DE-600)1458410-4 1432-0533 nnns volume:86 year:1993 month:01 pages:90-94 extent:5 http://dx.doi.org/10.1007/BF00454905 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 86 1993 1 90-94 5 |
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(DE-627)NLEJ203609379 DE-627 ger DE-627 rakwb eng Acute presentation of Tangier polyneuropathy: a clinical and morphological study 1993 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary We describe a patient with Tangier disease and a peripheral neuropathy with an unusual acute onset. The morphological studies of sural nerve biopsy revealed both axonal degeneration and demyelination, and the fiber loss was preferentially restricted to two of ten nerve fascicles. The cytoplasm of Schwann cells, fibroblasts, macrophages and pericytes were vacuolated because of the presence of numerous lipid droplets. The clinical and morphological findings are consistent with the possibility that ischemia plays a major role in causing this neuropathy. Springer Online Journal Archives 1860-2002 Fazio, Raffaella oth Nemni, Raffaello oth Quattrini, Angelo oth Ruotolo, Giacomo oth Iannaccone, Sandro oth Mamoli, Daniela oth Lodi, Monica oth Canal, Nicola oth in Acta neuropathologica 1961 86(1993) vom: Jan., Seite 90-94 (DE-627)NLEJ188990917 (DE-600)1458410-4 1432-0533 nnns volume:86 year:1993 month:01 pages:90-94 extent:5 http://dx.doi.org/10.1007/BF00454905 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 86 1993 1 90-94 5 |
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(DE-627)NLEJ203609379 DE-627 ger DE-627 rakwb eng Acute presentation of Tangier polyneuropathy: a clinical and morphological study 1993 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary We describe a patient with Tangier disease and a peripheral neuropathy with an unusual acute onset. The morphological studies of sural nerve biopsy revealed both axonal degeneration and demyelination, and the fiber loss was preferentially restricted to two of ten nerve fascicles. The cytoplasm of Schwann cells, fibroblasts, macrophages and pericytes were vacuolated because of the presence of numerous lipid droplets. The clinical and morphological findings are consistent with the possibility that ischemia plays a major role in causing this neuropathy. Springer Online Journal Archives 1860-2002 Fazio, Raffaella oth Nemni, Raffaello oth Quattrini, Angelo oth Ruotolo, Giacomo oth Iannaccone, Sandro oth Mamoli, Daniela oth Lodi, Monica oth Canal, Nicola oth in Acta neuropathologica 1961 86(1993) vom: Jan., Seite 90-94 (DE-627)NLEJ188990917 (DE-600)1458410-4 1432-0533 nnns volume:86 year:1993 month:01 pages:90-94 extent:5 http://dx.doi.org/10.1007/BF00454905 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 86 1993 1 90-94 5 |
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(DE-627)NLEJ203609379 DE-627 ger DE-627 rakwb eng Acute presentation of Tangier polyneuropathy: a clinical and morphological study 1993 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary We describe a patient with Tangier disease and a peripheral neuropathy with an unusual acute onset. The morphological studies of sural nerve biopsy revealed both axonal degeneration and demyelination, and the fiber loss was preferentially restricted to two of ten nerve fascicles. The cytoplasm of Schwann cells, fibroblasts, macrophages and pericytes were vacuolated because of the presence of numerous lipid droplets. The clinical and morphological findings are consistent with the possibility that ischemia plays a major role in causing this neuropathy. Springer Online Journal Archives 1860-2002 Fazio, Raffaella oth Nemni, Raffaello oth Quattrini, Angelo oth Ruotolo, Giacomo oth Iannaccone, Sandro oth Mamoli, Daniela oth Lodi, Monica oth Canal, Nicola oth in Acta neuropathologica 1961 86(1993) vom: Jan., Seite 90-94 (DE-627)NLEJ188990917 (DE-600)1458410-4 1432-0533 nnns volume:86 year:1993 month:01 pages:90-94 extent:5 http://dx.doi.org/10.1007/BF00454905 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 86 1993 1 90-94 5 |
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acute presentation of tangier polyneuropathy: a clinical and morphological study |
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Acute presentation of Tangier polyneuropathy: a clinical and morphological study |
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Summary We describe a patient with Tangier disease and a peripheral neuropathy with an unusual acute onset. The morphological studies of sural nerve biopsy revealed both axonal degeneration and demyelination, and the fiber loss was preferentially restricted to two of ten nerve fascicles. The cytoplasm of Schwann cells, fibroblasts, macrophages and pericytes were vacuolated because of the presence of numerous lipid droplets. The clinical and morphological findings are consistent with the possibility that ischemia plays a major role in causing this neuropathy. |
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Summary We describe a patient with Tangier disease and a peripheral neuropathy with an unusual acute onset. The morphological studies of sural nerve biopsy revealed both axonal degeneration and demyelination, and the fiber loss was preferentially restricted to two of ten nerve fascicles. The cytoplasm of Schwann cells, fibroblasts, macrophages and pericytes were vacuolated because of the presence of numerous lipid droplets. The clinical and morphological findings are consistent with the possibility that ischemia plays a major role in causing this neuropathy. |
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Summary We describe a patient with Tangier disease and a peripheral neuropathy with an unusual acute onset. The morphological studies of sural nerve biopsy revealed both axonal degeneration and demyelination, and the fiber loss was preferentially restricted to two of ten nerve fascicles. The cytoplasm of Schwann cells, fibroblasts, macrophages and pericytes were vacuolated because of the presence of numerous lipid droplets. The clinical and morphological findings are consistent with the possibility that ischemia plays a major role in causing this neuropathy. |
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Acute presentation of Tangier polyneuropathy: a clinical and morphological study |
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