Effect of actinomycin-D on the progesterone induced cytodifferentiation of the chick oviduct epithelium
Summary The effect of actinomycin D on the ultrastructural changes induced by 5 mg of progesterone in the immature chick oviduct epithelium was studied at 0–24h after injection. The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before pr...
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1978 |
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| Umfang: |
10 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: Histochemistry and cell biology - 1958, 55(1978) vom: März, Seite 251-260 |
| Übergeordnetes Werk: |
volume:55 ; year:1978 ; month:03 ; pages:251-260 ; extent:10 |
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NLEJ204391091 |
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| 245 | 1 | 0 | |a Effect of actinomycin-D on the progesterone induced cytodifferentiation of the chick oviduct epithelium |
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| 520 | |a Summary The effect of actinomycin D on the ultrastructural changes induced by 5 mg of progesterone in the immature chick oviduct epithelium was studied at 0–24h after injection. The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before progesterone, it inhibited the formation of secretory granules, whereas it could not prevent the formation of the organelles involved in protein synthesis (polysomes, rough endoplasmic reticulum, Golgi apparatus) and the increase in the amount of mitochondria. On the other hand, actinomycin D enhanced the formation of progesterone induced secretory granules if it was administered after the steroid. Apical vacuoles were present within 2h after a combined treatment with progesterone and actinomycin D. Actinomycin D did not affect the changes in the plasma membrane caused by progesterone. The formation of microvilli and cilia began 7 and 12h, respectively, after progesterone. The epithelial cell plasma membranes developed a marked interdigitation, first observable 2h after progesterone administration. The intercellular spaces were markedly wider after actinomycin D, but not after progesterone only. There were significant changes in nuclear morphology after actinomycin D and progesterone injections. There was marked nuclear shrinkage as well as a significant decrease in the amount of nuclear pores by 2h after actinomycin D, administered either before or after progesterone. The amount of perichromatin granules (35–45 nm) increased following actinomycin D administration. There were no changes in the other nuclear granules. With prior actinomycin D administration, the amount of nucleoli per nucleus was decreased 7h after progesterone, whereas their amount increased within 2h if the actinomycin D treatment followed progesterone injection. Actinomycin D and progesterone treatment increased the incidence of nucleolonemata. Detachment of heterochromatin from the nuclear membrane was slightly delayed by actinomycin D, when given before progesterone. The results can be explained on the basis of transcriptional and post-transcriptional effects of actinomycin D. | ||
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(DE-627)NLEJ204391091 DE-627 ger DE-627 rakwb eng Effect of actinomycin-D on the progesterone induced cytodifferentiation of the chick oviduct epithelium 1978 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The effect of actinomycin D on the ultrastructural changes induced by 5 mg of progesterone in the immature chick oviduct epithelium was studied at 0–24h after injection. The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before progesterone, it inhibited the formation of secretory granules, whereas it could not prevent the formation of the organelles involved in protein synthesis (polysomes, rough endoplasmic reticulum, Golgi apparatus) and the increase in the amount of mitochondria. On the other hand, actinomycin D enhanced the formation of progesterone induced secretory granules if it was administered after the steroid. Apical vacuoles were present within 2h after a combined treatment with progesterone and actinomycin D. Actinomycin D did not affect the changes in the plasma membrane caused by progesterone. The formation of microvilli and cilia began 7 and 12h, respectively, after progesterone. The epithelial cell plasma membranes developed a marked interdigitation, first observable 2h after progesterone administration. The intercellular spaces were markedly wider after actinomycin D, but not after progesterone only. There were significant changes in nuclear morphology after actinomycin D and progesterone injections. There was marked nuclear shrinkage as well as a significant decrease in the amount of nuclear pores by 2h after actinomycin D, administered either before or after progesterone. The amount of perichromatin granules (35–45 nm) increased following actinomycin D administration. There were no changes in the other nuclear granules. With prior actinomycin D administration, the amount of nucleoli per nucleus was decreased 7h after progesterone, whereas their amount increased within 2h if the actinomycin D treatment followed progesterone injection. Actinomycin D and progesterone treatment increased the incidence of nucleolonemata. Detachment of heterochromatin from the nuclear membrane was slightly delayed by actinomycin D, when given before progesterone. The results can be explained on the basis of transcriptional and post-transcriptional effects of actinomycin D. Springer Online Journal Archives 1860-2002 Kellokumpu-Lehtinen, P. oth Tuohimaa, P. oth in Histochemistry and cell biology 1958 55(1978) vom: März, Seite 251-260 (DE-627)NLEJ188988467 (DE-600)1398345-3 1432-119X nnns volume:55 year:1978 month:03 pages:251-260 extent:10 http://dx.doi.org/10.1007/BF00495764 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 55 1978 3 251-260 10 |
| spelling |
(DE-627)NLEJ204391091 DE-627 ger DE-627 rakwb eng Effect of actinomycin-D on the progesterone induced cytodifferentiation of the chick oviduct epithelium 1978 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The effect of actinomycin D on the ultrastructural changes induced by 5 mg of progesterone in the immature chick oviduct epithelium was studied at 0–24h after injection. The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before progesterone, it inhibited the formation of secretory granules, whereas it could not prevent the formation of the organelles involved in protein synthesis (polysomes, rough endoplasmic reticulum, Golgi apparatus) and the increase in the amount of mitochondria. On the other hand, actinomycin D enhanced the formation of progesterone induced secretory granules if it was administered after the steroid. Apical vacuoles were present within 2h after a combined treatment with progesterone and actinomycin D. Actinomycin D did not affect the changes in the plasma membrane caused by progesterone. The formation of microvilli and cilia began 7 and 12h, respectively, after progesterone. The epithelial cell plasma membranes developed a marked interdigitation, first observable 2h after progesterone administration. The intercellular spaces were markedly wider after actinomycin D, but not after progesterone only. There were significant changes in nuclear morphology after actinomycin D and progesterone injections. There was marked nuclear shrinkage as well as a significant decrease in the amount of nuclear pores by 2h after actinomycin D, administered either before or after progesterone. The amount of perichromatin granules (35–45 nm) increased following actinomycin D administration. There were no changes in the other nuclear granules. With prior actinomycin D administration, the amount of nucleoli per nucleus was decreased 7h after progesterone, whereas their amount increased within 2h if the actinomycin D treatment followed progesterone injection. Actinomycin D and progesterone treatment increased the incidence of nucleolonemata. Detachment of heterochromatin from the nuclear membrane was slightly delayed by actinomycin D, when given before progesterone. The results can be explained on the basis of transcriptional and post-transcriptional effects of actinomycin D. Springer Online Journal Archives 1860-2002 Kellokumpu-Lehtinen, P. oth Tuohimaa, P. oth in Histochemistry and cell biology 1958 55(1978) vom: März, Seite 251-260 (DE-627)NLEJ188988467 (DE-600)1398345-3 1432-119X nnns volume:55 year:1978 month:03 pages:251-260 extent:10 http://dx.doi.org/10.1007/BF00495764 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 55 1978 3 251-260 10 |
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(DE-627)NLEJ204391091 DE-627 ger DE-627 rakwb eng Effect of actinomycin-D on the progesterone induced cytodifferentiation of the chick oviduct epithelium 1978 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The effect of actinomycin D on the ultrastructural changes induced by 5 mg of progesterone in the immature chick oviduct epithelium was studied at 0–24h after injection. The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before progesterone, it inhibited the formation of secretory granules, whereas it could not prevent the formation of the organelles involved in protein synthesis (polysomes, rough endoplasmic reticulum, Golgi apparatus) and the increase in the amount of mitochondria. On the other hand, actinomycin D enhanced the formation of progesterone induced secretory granules if it was administered after the steroid. Apical vacuoles were present within 2h after a combined treatment with progesterone and actinomycin D. Actinomycin D did not affect the changes in the plasma membrane caused by progesterone. The formation of microvilli and cilia began 7 and 12h, respectively, after progesterone. The epithelial cell plasma membranes developed a marked interdigitation, first observable 2h after progesterone administration. The intercellular spaces were markedly wider after actinomycin D, but not after progesterone only. There were significant changes in nuclear morphology after actinomycin D and progesterone injections. There was marked nuclear shrinkage as well as a significant decrease in the amount of nuclear pores by 2h after actinomycin D, administered either before or after progesterone. The amount of perichromatin granules (35–45 nm) increased following actinomycin D administration. There were no changes in the other nuclear granules. With prior actinomycin D administration, the amount of nucleoli per nucleus was decreased 7h after progesterone, whereas their amount increased within 2h if the actinomycin D treatment followed progesterone injection. Actinomycin D and progesterone treatment increased the incidence of nucleolonemata. Detachment of heterochromatin from the nuclear membrane was slightly delayed by actinomycin D, when given before progesterone. The results can be explained on the basis of transcriptional and post-transcriptional effects of actinomycin D. Springer Online Journal Archives 1860-2002 Kellokumpu-Lehtinen, P. oth Tuohimaa, P. oth in Histochemistry and cell biology 1958 55(1978) vom: März, Seite 251-260 (DE-627)NLEJ188988467 (DE-600)1398345-3 1432-119X nnns volume:55 year:1978 month:03 pages:251-260 extent:10 http://dx.doi.org/10.1007/BF00495764 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 55 1978 3 251-260 10 |
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(DE-627)NLEJ204391091 DE-627 ger DE-627 rakwb eng Effect of actinomycin-D on the progesterone induced cytodifferentiation of the chick oviduct epithelium 1978 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The effect of actinomycin D on the ultrastructural changes induced by 5 mg of progesterone in the immature chick oviduct epithelium was studied at 0–24h after injection. The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before progesterone, it inhibited the formation of secretory granules, whereas it could not prevent the formation of the organelles involved in protein synthesis (polysomes, rough endoplasmic reticulum, Golgi apparatus) and the increase in the amount of mitochondria. On the other hand, actinomycin D enhanced the formation of progesterone induced secretory granules if it was administered after the steroid. Apical vacuoles were present within 2h after a combined treatment with progesterone and actinomycin D. Actinomycin D did not affect the changes in the plasma membrane caused by progesterone. The formation of microvilli and cilia began 7 and 12h, respectively, after progesterone. The epithelial cell plasma membranes developed a marked interdigitation, first observable 2h after progesterone administration. The intercellular spaces were markedly wider after actinomycin D, but not after progesterone only. There were significant changes in nuclear morphology after actinomycin D and progesterone injections. There was marked nuclear shrinkage as well as a significant decrease in the amount of nuclear pores by 2h after actinomycin D, administered either before or after progesterone. The amount of perichromatin granules (35–45 nm) increased following actinomycin D administration. There were no changes in the other nuclear granules. With prior actinomycin D administration, the amount of nucleoli per nucleus was decreased 7h after progesterone, whereas their amount increased within 2h if the actinomycin D treatment followed progesterone injection. Actinomycin D and progesterone treatment increased the incidence of nucleolonemata. Detachment of heterochromatin from the nuclear membrane was slightly delayed by actinomycin D, when given before progesterone. The results can be explained on the basis of transcriptional and post-transcriptional effects of actinomycin D. Springer Online Journal Archives 1860-2002 Kellokumpu-Lehtinen, P. oth Tuohimaa, P. oth in Histochemistry and cell biology 1958 55(1978) vom: März, Seite 251-260 (DE-627)NLEJ188988467 (DE-600)1398345-3 1432-119X nnns volume:55 year:1978 month:03 pages:251-260 extent:10 http://dx.doi.org/10.1007/BF00495764 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 55 1978 3 251-260 10 |
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(DE-627)NLEJ204391091 DE-627 ger DE-627 rakwb eng Effect of actinomycin-D on the progesterone induced cytodifferentiation of the chick oviduct epithelium 1978 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The effect of actinomycin D on the ultrastructural changes induced by 5 mg of progesterone in the immature chick oviduct epithelium was studied at 0–24h after injection. The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before progesterone, it inhibited the formation of secretory granules, whereas it could not prevent the formation of the organelles involved in protein synthesis (polysomes, rough endoplasmic reticulum, Golgi apparatus) and the increase in the amount of mitochondria. On the other hand, actinomycin D enhanced the formation of progesterone induced secretory granules if it was administered after the steroid. Apical vacuoles were present within 2h after a combined treatment with progesterone and actinomycin D. Actinomycin D did not affect the changes in the plasma membrane caused by progesterone. The formation of microvilli and cilia began 7 and 12h, respectively, after progesterone. The epithelial cell plasma membranes developed a marked interdigitation, first observable 2h after progesterone administration. The intercellular spaces were markedly wider after actinomycin D, but not after progesterone only. There were significant changes in nuclear morphology after actinomycin D and progesterone injections. There was marked nuclear shrinkage as well as a significant decrease in the amount of nuclear pores by 2h after actinomycin D, administered either before or after progesterone. The amount of perichromatin granules (35–45 nm) increased following actinomycin D administration. There were no changes in the other nuclear granules. With prior actinomycin D administration, the amount of nucleoli per nucleus was decreased 7h after progesterone, whereas their amount increased within 2h if the actinomycin D treatment followed progesterone injection. Actinomycin D and progesterone treatment increased the incidence of nucleolonemata. Detachment of heterochromatin from the nuclear membrane was slightly delayed by actinomycin D, when given before progesterone. The results can be explained on the basis of transcriptional and post-transcriptional effects of actinomycin D. Springer Online Journal Archives 1860-2002 Kellokumpu-Lehtinen, P. oth Tuohimaa, P. oth in Histochemistry and cell biology 1958 55(1978) vom: März, Seite 251-260 (DE-627)NLEJ188988467 (DE-600)1398345-3 1432-119X nnns volume:55 year:1978 month:03 pages:251-260 extent:10 http://dx.doi.org/10.1007/BF00495764 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 55 1978 3 251-260 10 |
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in Histochemistry and cell biology 55(1978) vom: März, Seite 251-260 volume:55 year:1978 month:03 pages:251-260 extent:10 |
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The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before progesterone, it inhibited the formation of secretory granules, whereas it could not prevent the formation of the organelles involved in protein synthesis (polysomes, rough endoplasmic reticulum, Golgi apparatus) and the increase in the amount of mitochondria. On the other hand, actinomycin D enhanced the formation of progesterone induced secretory granules if it was administered after the steroid. Apical vacuoles were present within 2h after a combined treatment with progesterone and actinomycin D. Actinomycin D did not affect the changes in the plasma membrane caused by progesterone. The formation of microvilli and cilia began 7 and 12h, respectively, after progesterone. The epithelial cell plasma membranes developed a marked interdigitation, first observable 2h after progesterone administration. The intercellular spaces were markedly wider after actinomycin D, but not after progesterone only. There were significant changes in nuclear morphology after actinomycin D and progesterone injections. There was marked nuclear shrinkage as well as a significant decrease in the amount of nuclear pores by 2h after actinomycin D, administered either before or after progesterone. The amount of perichromatin granules (35–45 nm) increased following actinomycin D administration. There were no changes in the other nuclear granules. With prior actinomycin D administration, the amount of nucleoli per nucleus was decreased 7h after progesterone, whereas their amount increased within 2h if the actinomycin D treatment followed progesterone injection. Actinomycin D and progesterone treatment increased the incidence of nucleolonemata. Detachment of heterochromatin from the nuclear membrane was slightly delayed by actinomycin D, when given before progesterone. 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effect of actinomycin-d on the progesterone induced cytodifferentiation of the chick oviduct epithelium |
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Effect of actinomycin-D on the progesterone induced cytodifferentiation of the chick oviduct epithelium |
| abstract |
Summary The effect of actinomycin D on the ultrastructural changes induced by 5 mg of progesterone in the immature chick oviduct epithelium was studied at 0–24h after injection. The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before progesterone, it inhibited the formation of secretory granules, whereas it could not prevent the formation of the organelles involved in protein synthesis (polysomes, rough endoplasmic reticulum, Golgi apparatus) and the increase in the amount of mitochondria. On the other hand, actinomycin D enhanced the formation of progesterone induced secretory granules if it was administered after the steroid. Apical vacuoles were present within 2h after a combined treatment with progesterone and actinomycin D. Actinomycin D did not affect the changes in the plasma membrane caused by progesterone. The formation of microvilli and cilia began 7 and 12h, respectively, after progesterone. The epithelial cell plasma membranes developed a marked interdigitation, first observable 2h after progesterone administration. The intercellular spaces were markedly wider after actinomycin D, but not after progesterone only. There were significant changes in nuclear morphology after actinomycin D and progesterone injections. There was marked nuclear shrinkage as well as a significant decrease in the amount of nuclear pores by 2h after actinomycin D, administered either before or after progesterone. The amount of perichromatin granules (35–45 nm) increased following actinomycin D administration. There were no changes in the other nuclear granules. With prior actinomycin D administration, the amount of nucleoli per nucleus was decreased 7h after progesterone, whereas their amount increased within 2h if the actinomycin D treatment followed progesterone injection. Actinomycin D and progesterone treatment increased the incidence of nucleolonemata. Detachment of heterochromatin from the nuclear membrane was slightly delayed by actinomycin D, when given before progesterone. The results can be explained on the basis of transcriptional and post-transcriptional effects of actinomycin D. |
| abstractGer |
Summary The effect of actinomycin D on the ultrastructural changes induced by 5 mg of progesterone in the immature chick oviduct epithelium was studied at 0–24h after injection. The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before progesterone, it inhibited the formation of secretory granules, whereas it could not prevent the formation of the organelles involved in protein synthesis (polysomes, rough endoplasmic reticulum, Golgi apparatus) and the increase in the amount of mitochondria. On the other hand, actinomycin D enhanced the formation of progesterone induced secretory granules if it was administered after the steroid. Apical vacuoles were present within 2h after a combined treatment with progesterone and actinomycin D. Actinomycin D did not affect the changes in the plasma membrane caused by progesterone. The formation of microvilli and cilia began 7 and 12h, respectively, after progesterone. The epithelial cell plasma membranes developed a marked interdigitation, first observable 2h after progesterone administration. The intercellular spaces were markedly wider after actinomycin D, but not after progesterone only. There were significant changes in nuclear morphology after actinomycin D and progesterone injections. There was marked nuclear shrinkage as well as a significant decrease in the amount of nuclear pores by 2h after actinomycin D, administered either before or after progesterone. The amount of perichromatin granules (35–45 nm) increased following actinomycin D administration. There were no changes in the other nuclear granules. With prior actinomycin D administration, the amount of nucleoli per nucleus was decreased 7h after progesterone, whereas their amount increased within 2h if the actinomycin D treatment followed progesterone injection. Actinomycin D and progesterone treatment increased the incidence of nucleolonemata. Detachment of heterochromatin from the nuclear membrane was slightly delayed by actinomycin D, when given before progesterone. The results can be explained on the basis of transcriptional and post-transcriptional effects of actinomycin D. |
| abstract_unstemmed |
Summary The effect of actinomycin D on the ultrastructural changes induced by 5 mg of progesterone in the immature chick oviduct epithelium was studied at 0–24h after injection. The height of the epithelium increased during the experimental period. When actinomycin D was given half an hour before progesterone, it inhibited the formation of secretory granules, whereas it could not prevent the formation of the organelles involved in protein synthesis (polysomes, rough endoplasmic reticulum, Golgi apparatus) and the increase in the amount of mitochondria. On the other hand, actinomycin D enhanced the formation of progesterone induced secretory granules if it was administered after the steroid. Apical vacuoles were present within 2h after a combined treatment with progesterone and actinomycin D. Actinomycin D did not affect the changes in the plasma membrane caused by progesterone. The formation of microvilli and cilia began 7 and 12h, respectively, after progesterone. The epithelial cell plasma membranes developed a marked interdigitation, first observable 2h after progesterone administration. The intercellular spaces were markedly wider after actinomycin D, but not after progesterone only. There were significant changes in nuclear morphology after actinomycin D and progesterone injections. There was marked nuclear shrinkage as well as a significant decrease in the amount of nuclear pores by 2h after actinomycin D, administered either before or after progesterone. The amount of perichromatin granules (35–45 nm) increased following actinomycin D administration. There were no changes in the other nuclear granules. With prior actinomycin D administration, the amount of nucleoli per nucleus was decreased 7h after progesterone, whereas their amount increased within 2h if the actinomycin D treatment followed progesterone injection. Actinomycin D and progesterone treatment increased the incidence of nucleolonemata. Detachment of heterochromatin from the nuclear membrane was slightly delayed by actinomycin D, when given before progesterone. The results can be explained on the basis of transcriptional and post-transcriptional effects of actinomycin D. |
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GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE |
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Effect of actinomycin-D on the progesterone induced cytodifferentiation of the chick oviduct epithelium |
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http://dx.doi.org/10.1007/BF00495764 |
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Kellokumpu-Lehtinen, P. Tuohimaa, P. |
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