Cadmium-enhanced gene expression in suspension-culture cells of tobacco
Abstract The effects of various concentrations of cadmium on Nicotiana tabacum L. cv. Xanthi suspension cells were examined. Surprisingly, certain concentrations of Cd (100–150 μM) stimulated growth of cell cultures considerably, whereas all other concentrations were inhibitory. Synthesis of DNA was...
Ausführliche Beschreibung
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| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1989 |
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| Umfang: |
7 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: Planta - 1925, 179(1989) vom: März, Seite 414-420 |
| Übergeordnetes Werk: |
volume:179 ; year:1989 ; month:03 ; pages:414-420 ; extent:7 |
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| 520 | |a Abstract The effects of various concentrations of cadmium on Nicotiana tabacum L. cv. Xanthi suspension cells were examined. Surprisingly, certain concentrations of Cd (100–150 μM) stimulated growth of cell cultures considerably, whereas all other concentrations were inhibitory. Synthesis of DNA was severly affected in a dose-dependent manner by Cd concentrations of 250 μM and higher. In contrast, RNA and protein synthesis were similarly stimulated by 100 μM Cd, thus indicating that enhancement of RNA synthesis was the primary cause for the observed stimulation of cell culture growth. The transient expression of a chimeric chloramphenicol-acetyltransferase gene was similarly affected by Cd. When the effects of other heavy metals (Cu, Zn, Pb, Co, Mn, Al) on these cellular processes were investigated, only Zn showed a comparable stimulation of RNA and protein synthesis, although a tenfold higher concentration of Zn compared with Cd was required. As Zn and Cd are chemically very similar, these results are discussed in view of the well-known role of Zn in the regulation of transcription. | ||
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(DE-627)NLEJ204740584 DE-627 ger DE-627 rakwb eng Cadmium-enhanced gene expression in suspension-culture cells of tobacco 1989 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract The effects of various concentrations of cadmium on Nicotiana tabacum L. cv. Xanthi suspension cells were examined. Surprisingly, certain concentrations of Cd (100–150 μM) stimulated growth of cell cultures considerably, whereas all other concentrations were inhibitory. Synthesis of DNA was severly affected in a dose-dependent manner by Cd concentrations of 250 μM and higher. In contrast, RNA and protein synthesis were similarly stimulated by 100 μM Cd, thus indicating that enhancement of RNA synthesis was the primary cause for the observed stimulation of cell culture growth. The transient expression of a chimeric chloramphenicol-acetyltransferase gene was similarly affected by Cd. When the effects of other heavy metals (Cu, Zn, Pb, Co, Mn, Al) on these cellular processes were investigated, only Zn showed a comparable stimulation of RNA and protein synthesis, although a tenfold higher concentration of Zn compared with Cd was required. As Zn and Cd are chemically very similar, these results are discussed in view of the well-known role of Zn in the regulation of transcription. Springer Online Journal Archives 1860-2002 Hirt, Heribert oth Casari, Georg oth Barta, Andrea oth in Planta 1925 179(1989) vom: März, Seite 414-420 (DE-627)NLEJ188985018 (DE-600)1463030-8 1432-2048 nnns volume:179 year:1989 month:03 pages:414-420 extent:7 http://dx.doi.org/10.1007/BF00391089 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 179 1989 3 414-420 7 |
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(DE-627)NLEJ204740584 DE-627 ger DE-627 rakwb eng Cadmium-enhanced gene expression in suspension-culture cells of tobacco 1989 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract The effects of various concentrations of cadmium on Nicotiana tabacum L. cv. Xanthi suspension cells were examined. Surprisingly, certain concentrations of Cd (100–150 μM) stimulated growth of cell cultures considerably, whereas all other concentrations were inhibitory. Synthesis of DNA was severly affected in a dose-dependent manner by Cd concentrations of 250 μM and higher. In contrast, RNA and protein synthesis were similarly stimulated by 100 μM Cd, thus indicating that enhancement of RNA synthesis was the primary cause for the observed stimulation of cell culture growth. The transient expression of a chimeric chloramphenicol-acetyltransferase gene was similarly affected by Cd. When the effects of other heavy metals (Cu, Zn, Pb, Co, Mn, Al) on these cellular processes were investigated, only Zn showed a comparable stimulation of RNA and protein synthesis, although a tenfold higher concentration of Zn compared with Cd was required. As Zn and Cd are chemically very similar, these results are discussed in view of the well-known role of Zn in the regulation of transcription. Springer Online Journal Archives 1860-2002 Hirt, Heribert oth Casari, Georg oth Barta, Andrea oth in Planta 1925 179(1989) vom: März, Seite 414-420 (DE-627)NLEJ188985018 (DE-600)1463030-8 1432-2048 nnns volume:179 year:1989 month:03 pages:414-420 extent:7 http://dx.doi.org/10.1007/BF00391089 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 179 1989 3 414-420 7 |
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(DE-627)NLEJ204740584 DE-627 ger DE-627 rakwb eng Cadmium-enhanced gene expression in suspension-culture cells of tobacco 1989 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract The effects of various concentrations of cadmium on Nicotiana tabacum L. cv. Xanthi suspension cells were examined. Surprisingly, certain concentrations of Cd (100–150 μM) stimulated growth of cell cultures considerably, whereas all other concentrations were inhibitory. Synthesis of DNA was severly affected in a dose-dependent manner by Cd concentrations of 250 μM and higher. In contrast, RNA and protein synthesis were similarly stimulated by 100 μM Cd, thus indicating that enhancement of RNA synthesis was the primary cause for the observed stimulation of cell culture growth. The transient expression of a chimeric chloramphenicol-acetyltransferase gene was similarly affected by Cd. When the effects of other heavy metals (Cu, Zn, Pb, Co, Mn, Al) on these cellular processes were investigated, only Zn showed a comparable stimulation of RNA and protein synthesis, although a tenfold higher concentration of Zn compared with Cd was required. As Zn and Cd are chemically very similar, these results are discussed in view of the well-known role of Zn in the regulation of transcription. Springer Online Journal Archives 1860-2002 Hirt, Heribert oth Casari, Georg oth Barta, Andrea oth in Planta 1925 179(1989) vom: März, Seite 414-420 (DE-627)NLEJ188985018 (DE-600)1463030-8 1432-2048 nnns volume:179 year:1989 month:03 pages:414-420 extent:7 http://dx.doi.org/10.1007/BF00391089 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 179 1989 3 414-420 7 |
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(DE-627)NLEJ204740584 DE-627 ger DE-627 rakwb eng Cadmium-enhanced gene expression in suspension-culture cells of tobacco 1989 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract The effects of various concentrations of cadmium on Nicotiana tabacum L. cv. Xanthi suspension cells were examined. Surprisingly, certain concentrations of Cd (100–150 μM) stimulated growth of cell cultures considerably, whereas all other concentrations were inhibitory. Synthesis of DNA was severly affected in a dose-dependent manner by Cd concentrations of 250 μM and higher. In contrast, RNA and protein synthesis were similarly stimulated by 100 μM Cd, thus indicating that enhancement of RNA synthesis was the primary cause for the observed stimulation of cell culture growth. The transient expression of a chimeric chloramphenicol-acetyltransferase gene was similarly affected by Cd. When the effects of other heavy metals (Cu, Zn, Pb, Co, Mn, Al) on these cellular processes were investigated, only Zn showed a comparable stimulation of RNA and protein synthesis, although a tenfold higher concentration of Zn compared with Cd was required. As Zn and Cd are chemically very similar, these results are discussed in view of the well-known role of Zn in the regulation of transcription. Springer Online Journal Archives 1860-2002 Hirt, Heribert oth Casari, Georg oth Barta, Andrea oth in Planta 1925 179(1989) vom: März, Seite 414-420 (DE-627)NLEJ188985018 (DE-600)1463030-8 1432-2048 nnns volume:179 year:1989 month:03 pages:414-420 extent:7 http://dx.doi.org/10.1007/BF00391089 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 179 1989 3 414-420 7 |
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(DE-627)NLEJ204740584 DE-627 ger DE-627 rakwb eng Cadmium-enhanced gene expression in suspension-culture cells of tobacco 1989 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract The effects of various concentrations of cadmium on Nicotiana tabacum L. cv. Xanthi suspension cells were examined. Surprisingly, certain concentrations of Cd (100–150 μM) stimulated growth of cell cultures considerably, whereas all other concentrations were inhibitory. Synthesis of DNA was severly affected in a dose-dependent manner by Cd concentrations of 250 μM and higher. In contrast, RNA and protein synthesis were similarly stimulated by 100 μM Cd, thus indicating that enhancement of RNA synthesis was the primary cause for the observed stimulation of cell culture growth. The transient expression of a chimeric chloramphenicol-acetyltransferase gene was similarly affected by Cd. When the effects of other heavy metals (Cu, Zn, Pb, Co, Mn, Al) on these cellular processes were investigated, only Zn showed a comparable stimulation of RNA and protein synthesis, although a tenfold higher concentration of Zn compared with Cd was required. As Zn and Cd are chemically very similar, these results are discussed in view of the well-known role of Zn in the regulation of transcription. Springer Online Journal Archives 1860-2002 Hirt, Heribert oth Casari, Georg oth Barta, Andrea oth in Planta 1925 179(1989) vom: März, Seite 414-420 (DE-627)NLEJ188985018 (DE-600)1463030-8 1432-2048 nnns volume:179 year:1989 month:03 pages:414-420 extent:7 http://dx.doi.org/10.1007/BF00391089 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 179 1989 3 414-420 7 |
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Cadmium-enhanced gene expression in suspension-culture cells of tobacco |
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Abstract The effects of various concentrations of cadmium on Nicotiana tabacum L. cv. Xanthi suspension cells were examined. Surprisingly, certain concentrations of Cd (100–150 μM) stimulated growth of cell cultures considerably, whereas all other concentrations were inhibitory. Synthesis of DNA was severly affected in a dose-dependent manner by Cd concentrations of 250 μM and higher. In contrast, RNA and protein synthesis were similarly stimulated by 100 μM Cd, thus indicating that enhancement of RNA synthesis was the primary cause for the observed stimulation of cell culture growth. The transient expression of a chimeric chloramphenicol-acetyltransferase gene was similarly affected by Cd. When the effects of other heavy metals (Cu, Zn, Pb, Co, Mn, Al) on these cellular processes were investigated, only Zn showed a comparable stimulation of RNA and protein synthesis, although a tenfold higher concentration of Zn compared with Cd was required. As Zn and Cd are chemically very similar, these results are discussed in view of the well-known role of Zn in the regulation of transcription. |
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Abstract The effects of various concentrations of cadmium on Nicotiana tabacum L. cv. Xanthi suspension cells were examined. Surprisingly, certain concentrations of Cd (100–150 μM) stimulated growth of cell cultures considerably, whereas all other concentrations were inhibitory. Synthesis of DNA was severly affected in a dose-dependent manner by Cd concentrations of 250 μM and higher. In contrast, RNA and protein synthesis were similarly stimulated by 100 μM Cd, thus indicating that enhancement of RNA synthesis was the primary cause for the observed stimulation of cell culture growth. The transient expression of a chimeric chloramphenicol-acetyltransferase gene was similarly affected by Cd. When the effects of other heavy metals (Cu, Zn, Pb, Co, Mn, Al) on these cellular processes were investigated, only Zn showed a comparable stimulation of RNA and protein synthesis, although a tenfold higher concentration of Zn compared with Cd was required. As Zn and Cd are chemically very similar, these results are discussed in view of the well-known role of Zn in the regulation of transcription. |
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Abstract The effects of various concentrations of cadmium on Nicotiana tabacum L. cv. Xanthi suspension cells were examined. Surprisingly, certain concentrations of Cd (100–150 μM) stimulated growth of cell cultures considerably, whereas all other concentrations were inhibitory. Synthesis of DNA was severly affected in a dose-dependent manner by Cd concentrations of 250 μM and higher. In contrast, RNA and protein synthesis were similarly stimulated by 100 μM Cd, thus indicating that enhancement of RNA synthesis was the primary cause for the observed stimulation of cell culture growth. The transient expression of a chimeric chloramphenicol-acetyltransferase gene was similarly affected by Cd. When the effects of other heavy metals (Cu, Zn, Pb, Co, Mn, Al) on these cellular processes were investigated, only Zn showed a comparable stimulation of RNA and protein synthesis, although a tenfold higher concentration of Zn compared with Cd was required. As Zn and Cd are chemically very similar, these results are discussed in view of the well-known role of Zn in the regulation of transcription. |
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