Interaction between trophozoites ofEntamoeba histolytica and the human intestinal cell line HT-29 in the presence or absence of leukocytes
Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytic...
Ausführliche Beschreibung
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Englisch |
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1993 |
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6 |
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Springer Online Journal Archives 1860-2002 |
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Übergeordnetes Werk: |
in: Parasitology research - 1928, 79(1993) vom: Feb., Seite 140-145 |
Übergeordnetes Werk: |
volume:79 ; year:1993 ; month:02 ; pages:140-145 ; extent:6 |
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520 | |a Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytica with the human colonic carcinoma cell line HT-29. Differentiated HT-29 cells are comparable to the mucosa cells to whichE. histolytica attaches physiologically. Adherence betweenE. histolytica trophozoites and HT-29 cells was effectively inhibited by glycoconjugates containing galactose, indicating the importance of the 170-kDa lectin ofE. histolytica in binding to intestinal cells. Adherence was not significantly inhibited by glycoconjugates containingN-acetyl-glucosamine, indicating that the 220-kDa lectin ofE. histolytica is not involved in binding to HT-29 cells. The destruction of HT-29 cells by pathogenicE. histolytica was dependent on adherence. The destruction was enhanced when polymorphonuclear granulocytes were added to theE. histolytica trophozoites. | ||
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(DE-627)NLEJ205415601 DE-627 ger DE-627 rakwb eng Interaction between trophozoites ofEntamoeba histolytica and the human intestinal cell line HT-29 in the presence or absence of leukocytes 1993 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytica with the human colonic carcinoma cell line HT-29. Differentiated HT-29 cells are comparable to the mucosa cells to whichE. histolytica attaches physiologically. Adherence betweenE. histolytica trophozoites and HT-29 cells was effectively inhibited by glycoconjugates containing galactose, indicating the importance of the 170-kDa lectin ofE. histolytica in binding to intestinal cells. Adherence was not significantly inhibited by glycoconjugates containingN-acetyl-glucosamine, indicating that the 220-kDa lectin ofE. histolytica is not involved in binding to HT-29 cells. The destruction of HT-29 cells by pathogenicE. histolytica was dependent on adherence. The destruction was enhanced when polymorphonuclear granulocytes were added to theE. histolytica trophozoites. Springer Online Journal Archives 1860-2002 Burchard, G. D. oth Prange, G. oth Mirelman, D. oth in Parasitology research 1928 79(1993) vom: Feb., Seite 140-145 (DE-627)NLEJ18899467X (DE-600)1462976-8 1432-1955 nnns volume:79 year:1993 month:02 pages:140-145 extent:6 http://dx.doi.org/10.1007/BF00932260 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 79 1993 2 140-145 6 |
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(DE-627)NLEJ205415601 DE-627 ger DE-627 rakwb eng Interaction between trophozoites ofEntamoeba histolytica and the human intestinal cell line HT-29 in the presence or absence of leukocytes 1993 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytica with the human colonic carcinoma cell line HT-29. Differentiated HT-29 cells are comparable to the mucosa cells to whichE. histolytica attaches physiologically. Adherence betweenE. histolytica trophozoites and HT-29 cells was effectively inhibited by glycoconjugates containing galactose, indicating the importance of the 170-kDa lectin ofE. histolytica in binding to intestinal cells. Adherence was not significantly inhibited by glycoconjugates containingN-acetyl-glucosamine, indicating that the 220-kDa lectin ofE. histolytica is not involved in binding to HT-29 cells. The destruction of HT-29 cells by pathogenicE. histolytica was dependent on adherence. The destruction was enhanced when polymorphonuclear granulocytes were added to theE. histolytica trophozoites. Springer Online Journal Archives 1860-2002 Burchard, G. D. oth Prange, G. oth Mirelman, D. oth in Parasitology research 1928 79(1993) vom: Feb., Seite 140-145 (DE-627)NLEJ18899467X (DE-600)1462976-8 1432-1955 nnns volume:79 year:1993 month:02 pages:140-145 extent:6 http://dx.doi.org/10.1007/BF00932260 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 79 1993 2 140-145 6 |
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(DE-627)NLEJ205415601 DE-627 ger DE-627 rakwb eng Interaction between trophozoites ofEntamoeba histolytica and the human intestinal cell line HT-29 in the presence or absence of leukocytes 1993 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytica with the human colonic carcinoma cell line HT-29. Differentiated HT-29 cells are comparable to the mucosa cells to whichE. histolytica attaches physiologically. Adherence betweenE. histolytica trophozoites and HT-29 cells was effectively inhibited by glycoconjugates containing galactose, indicating the importance of the 170-kDa lectin ofE. histolytica in binding to intestinal cells. Adherence was not significantly inhibited by glycoconjugates containingN-acetyl-glucosamine, indicating that the 220-kDa lectin ofE. histolytica is not involved in binding to HT-29 cells. The destruction of HT-29 cells by pathogenicE. histolytica was dependent on adherence. The destruction was enhanced when polymorphonuclear granulocytes were added to theE. histolytica trophozoites. Springer Online Journal Archives 1860-2002 Burchard, G. D. oth Prange, G. oth Mirelman, D. oth in Parasitology research 1928 79(1993) vom: Feb., Seite 140-145 (DE-627)NLEJ18899467X (DE-600)1462976-8 1432-1955 nnns volume:79 year:1993 month:02 pages:140-145 extent:6 http://dx.doi.org/10.1007/BF00932260 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 79 1993 2 140-145 6 |
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(DE-627)NLEJ205415601 DE-627 ger DE-627 rakwb eng Interaction between trophozoites ofEntamoeba histolytica and the human intestinal cell line HT-29 in the presence or absence of leukocytes 1993 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytica with the human colonic carcinoma cell line HT-29. Differentiated HT-29 cells are comparable to the mucosa cells to whichE. histolytica attaches physiologically. Adherence betweenE. histolytica trophozoites and HT-29 cells was effectively inhibited by glycoconjugates containing galactose, indicating the importance of the 170-kDa lectin ofE. histolytica in binding to intestinal cells. Adherence was not significantly inhibited by glycoconjugates containingN-acetyl-glucosamine, indicating that the 220-kDa lectin ofE. histolytica is not involved in binding to HT-29 cells. The destruction of HT-29 cells by pathogenicE. histolytica was dependent on adherence. The destruction was enhanced when polymorphonuclear granulocytes were added to theE. histolytica trophozoites. Springer Online Journal Archives 1860-2002 Burchard, G. D. oth Prange, G. oth Mirelman, D. oth in Parasitology research 1928 79(1993) vom: Feb., Seite 140-145 (DE-627)NLEJ18899467X (DE-600)1462976-8 1432-1955 nnns volume:79 year:1993 month:02 pages:140-145 extent:6 http://dx.doi.org/10.1007/BF00932260 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 79 1993 2 140-145 6 |
allfieldsSound |
(DE-627)NLEJ205415601 DE-627 ger DE-627 rakwb eng Interaction between trophozoites ofEntamoeba histolytica and the human intestinal cell line HT-29 in the presence or absence of leukocytes 1993 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytica with the human colonic carcinoma cell line HT-29. Differentiated HT-29 cells are comparable to the mucosa cells to whichE. histolytica attaches physiologically. Adherence betweenE. histolytica trophozoites and HT-29 cells was effectively inhibited by glycoconjugates containing galactose, indicating the importance of the 170-kDa lectin ofE. histolytica in binding to intestinal cells. Adherence was not significantly inhibited by glycoconjugates containingN-acetyl-glucosamine, indicating that the 220-kDa lectin ofE. histolytica is not involved in binding to HT-29 cells. The destruction of HT-29 cells by pathogenicE. histolytica was dependent on adherence. The destruction was enhanced when polymorphonuclear granulocytes were added to theE. histolytica trophozoites. Springer Online Journal Archives 1860-2002 Burchard, G. D. oth Prange, G. oth Mirelman, D. oth in Parasitology research 1928 79(1993) vom: Feb., Seite 140-145 (DE-627)NLEJ18899467X (DE-600)1462976-8 1432-1955 nnns volume:79 year:1993 month:02 pages:140-145 extent:6 http://dx.doi.org/10.1007/BF00932260 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 79 1993 2 140-145 6 |
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interaction between trophozoites ofentamoeba histolytica and the human intestinal cell line ht-29 in the presence or absence of leukocytes |
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Interaction between trophozoites ofEntamoeba histolytica and the human intestinal cell line HT-29 in the presence or absence of leukocytes |
abstract |
Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytica with the human colonic carcinoma cell line HT-29. Differentiated HT-29 cells are comparable to the mucosa cells to whichE. histolytica attaches physiologically. Adherence betweenE. histolytica trophozoites and HT-29 cells was effectively inhibited by glycoconjugates containing galactose, indicating the importance of the 170-kDa lectin ofE. histolytica in binding to intestinal cells. Adherence was not significantly inhibited by glycoconjugates containingN-acetyl-glucosamine, indicating that the 220-kDa lectin ofE. histolytica is not involved in binding to HT-29 cells. The destruction of HT-29 cells by pathogenicE. histolytica was dependent on adherence. The destruction was enhanced when polymorphonuclear granulocytes were added to theE. histolytica trophozoites. |
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Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytica with the human colonic carcinoma cell line HT-29. Differentiated HT-29 cells are comparable to the mucosa cells to whichE. histolytica attaches physiologically. Adherence betweenE. histolytica trophozoites and HT-29 cells was effectively inhibited by glycoconjugates containing galactose, indicating the importance of the 170-kDa lectin ofE. histolytica in binding to intestinal cells. Adherence was not significantly inhibited by glycoconjugates containingN-acetyl-glucosamine, indicating that the 220-kDa lectin ofE. histolytica is not involved in binding to HT-29 cells. The destruction of HT-29 cells by pathogenicE. histolytica was dependent on adherence. The destruction was enhanced when polymorphonuclear granulocytes were added to theE. histolytica trophozoites. |
abstract_unstemmed |
Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytica with the human colonic carcinoma cell line HT-29. Differentiated HT-29 cells are comparable to the mucosa cells to whichE. histolytica attaches physiologically. Adherence betweenE. histolytica trophozoites and HT-29 cells was effectively inhibited by glycoconjugates containing galactose, indicating the importance of the 170-kDa lectin ofE. histolytica in binding to intestinal cells. Adherence was not significantly inhibited by glycoconjugates containingN-acetyl-glucosamine, indicating that the 220-kDa lectin ofE. histolytica is not involved in binding to HT-29 cells. The destruction of HT-29 cells by pathogenicE. histolytica was dependent on adherence. The destruction was enhanced when polymorphonuclear granulocytes were added to theE. histolytica trophozoites. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ205415601</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210706174931.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070528s1993 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ205415601</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Interaction between trophozoites ofEntamoeba histolytica and the human intestinal cell line HT-29 in the presence or absence of leukocytes</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1993</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">6</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Studies on the interaction between trophozoites ofEntamoeba histolytica of pathogenic or nonpathogenic origin and epithelial cells of the human intestine can contribute to the understanding of the pathogenesis of invasive amoebiasis. We have examined the interaction of virulentE. histolytica with the human colonic carcinoma cell line HT-29. Differentiated HT-29 cells are comparable to the mucosa cells to whichE. histolytica attaches physiologically. Adherence betweenE. histolytica trophozoites and HT-29 cells was effectively inhibited by glycoconjugates containing galactose, indicating the importance of the 170-kDa lectin ofE. histolytica in binding to intestinal cells. Adherence was not significantly inhibited by glycoconjugates containingN-acetyl-glucosamine, indicating that the 220-kDa lectin ofE. histolytica is not involved in binding to HT-29 cells. The destruction of HT-29 cells by pathogenicE. histolytica was dependent on adherence. The destruction was enhanced when polymorphonuclear granulocytes were added to theE. histolytica trophozoites.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Springer Online Journal Archives 1860-2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Burchard, G. D.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Prange, G.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mirelman, D.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Parasitology research</subfield><subfield code="d">1928</subfield><subfield code="g">79(1993) vom: Feb., Seite 140-145</subfield><subfield code="w">(DE-627)NLEJ18899467X</subfield><subfield code="w">(DE-600)1462976-8</subfield><subfield code="x">1432-1955</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:79</subfield><subfield code="g">year:1993</subfield><subfield code="g">month:02</subfield><subfield code="g">pages:140-145</subfield><subfield code="g">extent:6</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1007/BF00932260</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SOJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">79</subfield><subfield code="j">1993</subfield><subfield code="c">2</subfield><subfield code="h">140-145</subfield><subfield code="g">6</subfield></datafield></record></collection>
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