Fatal Pneumonia in an AIDS Patient Coinfected with Adenovirus and Pneumocystis carinii
Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in th...
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2000 |
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| Umfang: |
3 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: Infection - 1973, 28(2000) vom: Mai, Seite 323-325 |
| Übergeordnetes Werk: |
volume:28 ; year:2000 ; month:05 ; pages:323-325 ; extent:3 |
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| 520 | |a Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in the upper left lobe on chest X-ray. Bronchoscopy was performed and Pneumocystis carinii was detected in brochoalveolar lavage (BAL) fluid. Treatment with cotrimoxazole and prednisone intially resulted in improvement, but after 10 days the patient's clinical condition deteriorated rapidly and he died after 23 days due to respiratory failure. Results: On autopsy histopathologic examination showed abundant “smudge cells,” suggestive of adenoviral infection. Electron microscopy revealed adenovirus-like particles arrayed in a paracrystalline manner. Subsequent immunohistochemistry confirmed the extensive presence of adenovirus in addition to P. carinii. Conclusion: This case demonstrates a pathogenetic role for adenovirus coinfection i P. carinii pneumonia (PCP). Earlier diagnosis, e. g. by PCR analysis of the BAL fluid or transbronchial biopsy, might have led to the consideration of ribavirin treatment. | ||
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(DE-627)NLEJ206774435 DE-627 ger DE-627 rakwb eng Fatal Pneumonia in an AIDS Patient Coinfected with Adenovirus and Pneumocystis carinii 2000 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in the upper left lobe on chest X-ray. Bronchoscopy was performed and Pneumocystis carinii was detected in brochoalveolar lavage (BAL) fluid. Treatment with cotrimoxazole and prednisone intially resulted in improvement, but after 10 days the patient's clinical condition deteriorated rapidly and he died after 23 days due to respiratory failure. Results: On autopsy histopathologic examination showed abundant “smudge cells,” suggestive of adenoviral infection. Electron microscopy revealed adenovirus-like particles arrayed in a paracrystalline manner. Subsequent immunohistochemistry confirmed the extensive presence of adenovirus in addition to P. carinii. Conclusion: This case demonstrates a pathogenetic role for adenovirus coinfection i P. carinii pneumonia (PCP). Earlier diagnosis, e. g. by PCR analysis of the BAL fluid or transbronchial biopsy, might have led to the consideration of ribavirin treatment. Springer Online Journal Archives 1860-2002 Koopmann, J. oth Dombrowski, F. oth Rockstroh, J.K. oth Pfeifer, U. oth Sauerbruch, T. oth Spengler, U. oth in Infection 1973 28(2000) vom: Mai, Seite 323-325 (DE-627)NLEJ188985891 (DE-600)2006315-5 1439-0973 nnns volume:28 year:2000 month:05 pages:323-325 extent:3 http://dx.doi.org/10.1007/s150100070028 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 28 2000 5 323-325 3 |
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(DE-627)NLEJ206774435 DE-627 ger DE-627 rakwb eng Fatal Pneumonia in an AIDS Patient Coinfected with Adenovirus and Pneumocystis carinii 2000 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in the upper left lobe on chest X-ray. Bronchoscopy was performed and Pneumocystis carinii was detected in brochoalveolar lavage (BAL) fluid. Treatment with cotrimoxazole and prednisone intially resulted in improvement, but after 10 days the patient's clinical condition deteriorated rapidly and he died after 23 days due to respiratory failure. Results: On autopsy histopathologic examination showed abundant “smudge cells,” suggestive of adenoviral infection. Electron microscopy revealed adenovirus-like particles arrayed in a paracrystalline manner. Subsequent immunohistochemistry confirmed the extensive presence of adenovirus in addition to P. carinii. Conclusion: This case demonstrates a pathogenetic role for adenovirus coinfection i P. carinii pneumonia (PCP). Earlier diagnosis, e. g. by PCR analysis of the BAL fluid or transbronchial biopsy, might have led to the consideration of ribavirin treatment. Springer Online Journal Archives 1860-2002 Koopmann, J. oth Dombrowski, F. oth Rockstroh, J.K. oth Pfeifer, U. oth Sauerbruch, T. oth Spengler, U. oth in Infection 1973 28(2000) vom: Mai, Seite 323-325 (DE-627)NLEJ188985891 (DE-600)2006315-5 1439-0973 nnns volume:28 year:2000 month:05 pages:323-325 extent:3 http://dx.doi.org/10.1007/s150100070028 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 28 2000 5 323-325 3 |
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(DE-627)NLEJ206774435 DE-627 ger DE-627 rakwb eng Fatal Pneumonia in an AIDS Patient Coinfected with Adenovirus and Pneumocystis carinii 2000 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in the upper left lobe on chest X-ray. Bronchoscopy was performed and Pneumocystis carinii was detected in brochoalveolar lavage (BAL) fluid. Treatment with cotrimoxazole and prednisone intially resulted in improvement, but after 10 days the patient's clinical condition deteriorated rapidly and he died after 23 days due to respiratory failure. Results: On autopsy histopathologic examination showed abundant “smudge cells,” suggestive of adenoviral infection. Electron microscopy revealed adenovirus-like particles arrayed in a paracrystalline manner. Subsequent immunohistochemistry confirmed the extensive presence of adenovirus in addition to P. carinii. Conclusion: This case demonstrates a pathogenetic role for adenovirus coinfection i P. carinii pneumonia (PCP). Earlier diagnosis, e. g. by PCR analysis of the BAL fluid or transbronchial biopsy, might have led to the consideration of ribavirin treatment. Springer Online Journal Archives 1860-2002 Koopmann, J. oth Dombrowski, F. oth Rockstroh, J.K. oth Pfeifer, U. oth Sauerbruch, T. oth Spengler, U. oth in Infection 1973 28(2000) vom: Mai, Seite 323-325 (DE-627)NLEJ188985891 (DE-600)2006315-5 1439-0973 nnns volume:28 year:2000 month:05 pages:323-325 extent:3 http://dx.doi.org/10.1007/s150100070028 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 28 2000 5 323-325 3 |
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(DE-627)NLEJ206774435 DE-627 ger DE-627 rakwb eng Fatal Pneumonia in an AIDS Patient Coinfected with Adenovirus and Pneumocystis carinii 2000 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in the upper left lobe on chest X-ray. Bronchoscopy was performed and Pneumocystis carinii was detected in brochoalveolar lavage (BAL) fluid. Treatment with cotrimoxazole and prednisone intially resulted in improvement, but after 10 days the patient's clinical condition deteriorated rapidly and he died after 23 days due to respiratory failure. Results: On autopsy histopathologic examination showed abundant “smudge cells,” suggestive of adenoviral infection. Electron microscopy revealed adenovirus-like particles arrayed in a paracrystalline manner. Subsequent immunohistochemistry confirmed the extensive presence of adenovirus in addition to P. carinii. Conclusion: This case demonstrates a pathogenetic role for adenovirus coinfection i P. carinii pneumonia (PCP). Earlier diagnosis, e. g. by PCR analysis of the BAL fluid or transbronchial biopsy, might have led to the consideration of ribavirin treatment. Springer Online Journal Archives 1860-2002 Koopmann, J. oth Dombrowski, F. oth Rockstroh, J.K. oth Pfeifer, U. oth Sauerbruch, T. oth Spengler, U. oth in Infection 1973 28(2000) vom: Mai, Seite 323-325 (DE-627)NLEJ188985891 (DE-600)2006315-5 1439-0973 nnns volume:28 year:2000 month:05 pages:323-325 extent:3 http://dx.doi.org/10.1007/s150100070028 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 28 2000 5 323-325 3 |
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(DE-627)NLEJ206774435 DE-627 ger DE-627 rakwb eng Fatal Pneumonia in an AIDS Patient Coinfected with Adenovirus and Pneumocystis carinii 2000 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in the upper left lobe on chest X-ray. Bronchoscopy was performed and Pneumocystis carinii was detected in brochoalveolar lavage (BAL) fluid. Treatment with cotrimoxazole and prednisone intially resulted in improvement, but after 10 days the patient's clinical condition deteriorated rapidly and he died after 23 days due to respiratory failure. Results: On autopsy histopathologic examination showed abundant “smudge cells,” suggestive of adenoviral infection. Electron microscopy revealed adenovirus-like particles arrayed in a paracrystalline manner. Subsequent immunohistochemistry confirmed the extensive presence of adenovirus in addition to P. carinii. Conclusion: This case demonstrates a pathogenetic role for adenovirus coinfection i P. carinii pneumonia (PCP). Earlier diagnosis, e. g. by PCR analysis of the BAL fluid or transbronchial biopsy, might have led to the consideration of ribavirin treatment. Springer Online Journal Archives 1860-2002 Koopmann, J. oth Dombrowski, F. oth Rockstroh, J.K. oth Pfeifer, U. oth Sauerbruch, T. oth Spengler, U. oth in Infection 1973 28(2000) vom: Mai, Seite 323-325 (DE-627)NLEJ188985891 (DE-600)2006315-5 1439-0973 nnns volume:28 year:2000 month:05 pages:323-325 extent:3 http://dx.doi.org/10.1007/s150100070028 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 28 2000 5 323-325 3 |
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fatal pneumonia in an aids patient coinfected with adenovirus and pneumocystis carinii |
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Fatal Pneumonia in an AIDS Patient Coinfected with Adenovirus and Pneumocystis carinii |
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Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in the upper left lobe on chest X-ray. Bronchoscopy was performed and Pneumocystis carinii was detected in brochoalveolar lavage (BAL) fluid. Treatment with cotrimoxazole and prednisone intially resulted in improvement, but after 10 days the patient's clinical condition deteriorated rapidly and he died after 23 days due to respiratory failure. Results: On autopsy histopathologic examination showed abundant “smudge cells,” suggestive of adenoviral infection. Electron microscopy revealed adenovirus-like particles arrayed in a paracrystalline manner. Subsequent immunohistochemistry confirmed the extensive presence of adenovirus in addition to P. carinii. Conclusion: This case demonstrates a pathogenetic role for adenovirus coinfection i P. carinii pneumonia (PCP). Earlier diagnosis, e. g. by PCR analysis of the BAL fluid or transbronchial biopsy, might have led to the consideration of ribavirin treatment. |
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Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in the upper left lobe on chest X-ray. Bronchoscopy was performed and Pneumocystis carinii was detected in brochoalveolar lavage (BAL) fluid. Treatment with cotrimoxazole and prednisone intially resulted in improvement, but after 10 days the patient's clinical condition deteriorated rapidly and he died after 23 days due to respiratory failure. Results: On autopsy histopathologic examination showed abundant “smudge cells,” suggestive of adenoviral infection. Electron microscopy revealed adenovirus-like particles arrayed in a paracrystalline manner. Subsequent immunohistochemistry confirmed the extensive presence of adenovirus in addition to P. carinii. Conclusion: This case demonstrates a pathogenetic role for adenovirus coinfection i P. carinii pneumonia (PCP). Earlier diagnosis, e. g. by PCR analysis of the BAL fluid or transbronchial biopsy, might have led to the consideration of ribavirin treatment. |
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Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in the upper left lobe on chest X-ray. Bronchoscopy was performed and Pneumocystis carinii was detected in brochoalveolar lavage (BAL) fluid. Treatment with cotrimoxazole and prednisone intially resulted in improvement, but after 10 days the patient's clinical condition deteriorated rapidly and he died after 23 days due to respiratory failure. Results: On autopsy histopathologic examination showed abundant “smudge cells,” suggestive of adenoviral infection. Electron microscopy revealed adenovirus-like particles arrayed in a paracrystalline manner. Subsequent immunohistochemistry confirmed the extensive presence of adenovirus in addition to P. carinii. Conclusion: This case demonstrates a pathogenetic role for adenovirus coinfection i P. carinii pneumonia (PCP). Earlier diagnosis, e. g. by PCR analysis of the BAL fluid or transbronchial biopsy, might have led to the consideration of ribavirin treatment. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ206774435</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230505190658.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070528s2000 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ206774435</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Fatal Pneumonia in an AIDS Patient Coinfected with Adenovirus and Pneumocystis carinii</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2000</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">3</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Summary Background: Adenovirus infections are common in immunocomproised hosts. However, pulmonary adenovirus infections rarely cause significant morbidity in HIV-infected patients. Patient: Here we described a 27-year-old man with AIDS who presented with tachypnea, hypoxemia and an infiltrate in the upper left lobe on chest X-ray. Bronchoscopy was performed and Pneumocystis carinii was detected in brochoalveolar lavage (BAL) fluid. Treatment with cotrimoxazole and prednisone intially resulted in improvement, but after 10 days the patient's clinical condition deteriorated rapidly and he died after 23 days due to respiratory failure. Results: On autopsy histopathologic examination showed abundant “smudge cells,” suggestive of adenoviral infection. Electron microscopy revealed adenovirus-like particles arrayed in a paracrystalline manner. Subsequent immunohistochemistry confirmed the extensive presence of adenovirus in addition to P. carinii. Conclusion: This case demonstrates a pathogenetic role for adenovirus coinfection i P. carinii pneumonia (PCP). Earlier diagnosis, e. g. by PCR analysis of the BAL fluid or transbronchial biopsy, might have led to the consideration of ribavirin treatment.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Springer Online Journal Archives 1860-2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Koopmann, J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dombrowski, F.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rockstroh, J.K.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pfeifer, U.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sauerbruch, T.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Spengler, U.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Infection</subfield><subfield code="d">1973</subfield><subfield code="g">28(2000) vom: Mai, Seite 323-325</subfield><subfield code="w">(DE-627)NLEJ188985891</subfield><subfield code="w">(DE-600)2006315-5</subfield><subfield code="x">1439-0973</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:28</subfield><subfield code="g">year:2000</subfield><subfield code="g">month:05</subfield><subfield code="g">pages:323-325</subfield><subfield code="g">extent:3</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1007/s150100070028</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SOJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">28</subfield><subfield code="j">2000</subfield><subfield code="c">5</subfield><subfield code="h">323-325</subfield><subfield code="g">3</subfield></datafield></record></collection>
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