Galactose transport in rabbit ileum
Summary The four unidirectional fluxes of galactose across the mucosal and serosal borders of rabbit ileum have been evaluated as functions of galactose concentration on a single piece of tissue from simultaneous measurements of mucosal-to-serosal and serosal-to-mucosal fluxes using14C- and3H-galact...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1974 |
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| Umfang: |
22 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: The journal of membrane biology - 1969, 16(1974) vom: Jan., Seite 257-278 |
| Übergeordnetes Werk: |
volume:16 ; year:1974 ; month:01 ; pages:257-278 ; extent:22 |
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NLEJ207050740 |
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| 245 | 1 | 0 | |a Galactose transport in rabbit ileum |
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| 520 | |a Summary The four unidirectional fluxes of galactose across the mucosal and serosal borders of rabbit ileum have been evaluated as functions of galactose concentration on a single piece of tissue from simultaneous measurements of mucosal-to-serosal and serosal-to-mucosal fluxes using14C- and3H-galactose and the steady-state ratio of the two isotopes in the tissue. The effects of Na removal, ouabain and a hypertonic serosal solution on these fluxes was investigated. Galactose was actively transported across the mucosal membrane under control conditions; this process was inhibited by Na removal and ouabain as a result of a decrease in flux from mucosal solution to cell and an increase in flux in the opposite direction. Effective galactose permeability of the serosal membrane was comparable to that of the mucosal membrane. Galactose transfer across the serosal membrane did not appear to conform to simple diffusion and may involve a facilitated transfer mechanism although a weak active transport from serosal solution to cell cannot be ruled out. Galactose movement at the serosal side of the cell was not influenced by Na. | ||
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| 700 | 1 | |a Curran, Peter F. |4 oth | |
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(DE-627)NLEJ207050740 DE-627 ger DE-627 rakwb eng Galactose transport in rabbit ileum 1974 22 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The four unidirectional fluxes of galactose across the mucosal and serosal borders of rabbit ileum have been evaluated as functions of galactose concentration on a single piece of tissue from simultaneous measurements of mucosal-to-serosal and serosal-to-mucosal fluxes using14C- and3H-galactose and the steady-state ratio of the two isotopes in the tissue. The effects of Na removal, ouabain and a hypertonic serosal solution on these fluxes was investigated. Galactose was actively transported across the mucosal membrane under control conditions; this process was inhibited by Na removal and ouabain as a result of a decrease in flux from mucosal solution to cell and an increase in flux in the opposite direction. Effective galactose permeability of the serosal membrane was comparable to that of the mucosal membrane. Galactose transfer across the serosal membrane did not appear to conform to simple diffusion and may involve a facilitated transfer mechanism although a weak active transport from serosal solution to cell cannot be ruled out. Galactose movement at the serosal side of the cell was not influenced by Na. Springer Online Journal Archives 1860-2002 Naftalin, Richard oth Curran, Peter F. oth in The journal of membrane biology 1969 16(1974) vom: Jan., Seite 257-278 (DE-627)NLEJ18899419X (DE-600)1459323-3 1432-1424 nnns volume:16 year:1974 month:01 pages:257-278 extent:22 http://dx.doi.org/10.1007/BF01872418 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 16 1974 1 257-278 22 |
| spelling |
(DE-627)NLEJ207050740 DE-627 ger DE-627 rakwb eng Galactose transport in rabbit ileum 1974 22 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The four unidirectional fluxes of galactose across the mucosal and serosal borders of rabbit ileum have been evaluated as functions of galactose concentration on a single piece of tissue from simultaneous measurements of mucosal-to-serosal and serosal-to-mucosal fluxes using14C- and3H-galactose and the steady-state ratio of the two isotopes in the tissue. The effects of Na removal, ouabain and a hypertonic serosal solution on these fluxes was investigated. Galactose was actively transported across the mucosal membrane under control conditions; this process was inhibited by Na removal and ouabain as a result of a decrease in flux from mucosal solution to cell and an increase in flux in the opposite direction. Effective galactose permeability of the serosal membrane was comparable to that of the mucosal membrane. Galactose transfer across the serosal membrane did not appear to conform to simple diffusion and may involve a facilitated transfer mechanism although a weak active transport from serosal solution to cell cannot be ruled out. Galactose movement at the serosal side of the cell was not influenced by Na. Springer Online Journal Archives 1860-2002 Naftalin, Richard oth Curran, Peter F. oth in The journal of membrane biology 1969 16(1974) vom: Jan., Seite 257-278 (DE-627)NLEJ18899419X (DE-600)1459323-3 1432-1424 nnns volume:16 year:1974 month:01 pages:257-278 extent:22 http://dx.doi.org/10.1007/BF01872418 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 16 1974 1 257-278 22 |
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(DE-627)NLEJ207050740 DE-627 ger DE-627 rakwb eng Galactose transport in rabbit ileum 1974 22 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The four unidirectional fluxes of galactose across the mucosal and serosal borders of rabbit ileum have been evaluated as functions of galactose concentration on a single piece of tissue from simultaneous measurements of mucosal-to-serosal and serosal-to-mucosal fluxes using14C- and3H-galactose and the steady-state ratio of the two isotopes in the tissue. The effects of Na removal, ouabain and a hypertonic serosal solution on these fluxes was investigated. Galactose was actively transported across the mucosal membrane under control conditions; this process was inhibited by Na removal and ouabain as a result of a decrease in flux from mucosal solution to cell and an increase in flux in the opposite direction. Effective galactose permeability of the serosal membrane was comparable to that of the mucosal membrane. Galactose transfer across the serosal membrane did not appear to conform to simple diffusion and may involve a facilitated transfer mechanism although a weak active transport from serosal solution to cell cannot be ruled out. Galactose movement at the serosal side of the cell was not influenced by Na. Springer Online Journal Archives 1860-2002 Naftalin, Richard oth Curran, Peter F. oth in The journal of membrane biology 1969 16(1974) vom: Jan., Seite 257-278 (DE-627)NLEJ18899419X (DE-600)1459323-3 1432-1424 nnns volume:16 year:1974 month:01 pages:257-278 extent:22 http://dx.doi.org/10.1007/BF01872418 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 16 1974 1 257-278 22 |
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(DE-627)NLEJ207050740 DE-627 ger DE-627 rakwb eng Galactose transport in rabbit ileum 1974 22 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The four unidirectional fluxes of galactose across the mucosal and serosal borders of rabbit ileum have been evaluated as functions of galactose concentration on a single piece of tissue from simultaneous measurements of mucosal-to-serosal and serosal-to-mucosal fluxes using14C- and3H-galactose and the steady-state ratio of the two isotopes in the tissue. The effects of Na removal, ouabain and a hypertonic serosal solution on these fluxes was investigated. Galactose was actively transported across the mucosal membrane under control conditions; this process was inhibited by Na removal and ouabain as a result of a decrease in flux from mucosal solution to cell and an increase in flux in the opposite direction. Effective galactose permeability of the serosal membrane was comparable to that of the mucosal membrane. Galactose transfer across the serosal membrane did not appear to conform to simple diffusion and may involve a facilitated transfer mechanism although a weak active transport from serosal solution to cell cannot be ruled out. Galactose movement at the serosal side of the cell was not influenced by Na. Springer Online Journal Archives 1860-2002 Naftalin, Richard oth Curran, Peter F. oth in The journal of membrane biology 1969 16(1974) vom: Jan., Seite 257-278 (DE-627)NLEJ18899419X (DE-600)1459323-3 1432-1424 nnns volume:16 year:1974 month:01 pages:257-278 extent:22 http://dx.doi.org/10.1007/BF01872418 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 16 1974 1 257-278 22 |
| allfieldsSound |
(DE-627)NLEJ207050740 DE-627 ger DE-627 rakwb eng Galactose transport in rabbit ileum 1974 22 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The four unidirectional fluxes of galactose across the mucosal and serosal borders of rabbit ileum have been evaluated as functions of galactose concentration on a single piece of tissue from simultaneous measurements of mucosal-to-serosal and serosal-to-mucosal fluxes using14C- and3H-galactose and the steady-state ratio of the two isotopes in the tissue. The effects of Na removal, ouabain and a hypertonic serosal solution on these fluxes was investigated. Galactose was actively transported across the mucosal membrane under control conditions; this process was inhibited by Na removal and ouabain as a result of a decrease in flux from mucosal solution to cell and an increase in flux in the opposite direction. Effective galactose permeability of the serosal membrane was comparable to that of the mucosal membrane. Galactose transfer across the serosal membrane did not appear to conform to simple diffusion and may involve a facilitated transfer mechanism although a weak active transport from serosal solution to cell cannot be ruled out. Galactose movement at the serosal side of the cell was not influenced by Na. Springer Online Journal Archives 1860-2002 Naftalin, Richard oth Curran, Peter F. oth in The journal of membrane biology 1969 16(1974) vom: Jan., Seite 257-278 (DE-627)NLEJ18899419X (DE-600)1459323-3 1432-1424 nnns volume:16 year:1974 month:01 pages:257-278 extent:22 http://dx.doi.org/10.1007/BF01872418 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 16 1974 1 257-278 22 |
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Galactose transport in rabbit ileum |
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Summary The four unidirectional fluxes of galactose across the mucosal and serosal borders of rabbit ileum have been evaluated as functions of galactose concentration on a single piece of tissue from simultaneous measurements of mucosal-to-serosal and serosal-to-mucosal fluxes using14C- and3H-galactose and the steady-state ratio of the two isotopes in the tissue. The effects of Na removal, ouabain and a hypertonic serosal solution on these fluxes was investigated. Galactose was actively transported across the mucosal membrane under control conditions; this process was inhibited by Na removal and ouabain as a result of a decrease in flux from mucosal solution to cell and an increase in flux in the opposite direction. Effective galactose permeability of the serosal membrane was comparable to that of the mucosal membrane. Galactose transfer across the serosal membrane did not appear to conform to simple diffusion and may involve a facilitated transfer mechanism although a weak active transport from serosal solution to cell cannot be ruled out. Galactose movement at the serosal side of the cell was not influenced by Na. |
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Summary The four unidirectional fluxes of galactose across the mucosal and serosal borders of rabbit ileum have been evaluated as functions of galactose concentration on a single piece of tissue from simultaneous measurements of mucosal-to-serosal and serosal-to-mucosal fluxes using14C- and3H-galactose and the steady-state ratio of the two isotopes in the tissue. The effects of Na removal, ouabain and a hypertonic serosal solution on these fluxes was investigated. Galactose was actively transported across the mucosal membrane under control conditions; this process was inhibited by Na removal and ouabain as a result of a decrease in flux from mucosal solution to cell and an increase in flux in the opposite direction. Effective galactose permeability of the serosal membrane was comparable to that of the mucosal membrane. Galactose transfer across the serosal membrane did not appear to conform to simple diffusion and may involve a facilitated transfer mechanism although a weak active transport from serosal solution to cell cannot be ruled out. Galactose movement at the serosal side of the cell was not influenced by Na. |
| abstract_unstemmed |
Summary The four unidirectional fluxes of galactose across the mucosal and serosal borders of rabbit ileum have been evaluated as functions of galactose concentration on a single piece of tissue from simultaneous measurements of mucosal-to-serosal and serosal-to-mucosal fluxes using14C- and3H-galactose and the steady-state ratio of the two isotopes in the tissue. The effects of Na removal, ouabain and a hypertonic serosal solution on these fluxes was investigated. Galactose was actively transported across the mucosal membrane under control conditions; this process was inhibited by Na removal and ouabain as a result of a decrease in flux from mucosal solution to cell and an increase in flux in the opposite direction. Effective galactose permeability of the serosal membrane was comparable to that of the mucosal membrane. Galactose transfer across the serosal membrane did not appear to conform to simple diffusion and may involve a facilitated transfer mechanism although a weak active transport from serosal solution to cell cannot be ruled out. Galactose movement at the serosal side of the cell was not influenced by Na. |
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