Sodium influx at the outer surface of frog skin
Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remai...
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1972 |
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| Umfang: |
12 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: The journal of membrane biology - 1969, 7(1972) vom: Jan., Seite 365-376 |
| Übergeordnetes Werk: |
volume:7 ; year:1972 ; month:01 ; pages:365-376 ; extent:12 |
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NLEJ207069476 |
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| 245 | 1 | 0 | |a Sodium influx at the outer surface of frog skin |
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| 520 | |a Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remaining on the surface of the skin after blotting. The space of distribution for3H-mannitol is about twice as large as the corresponding space for inulin after 32-sec exposure to the tracer. At a sodium concentration of 6.7mm the sodium influx determined with inulin as marker for the test solution is 0.146 μEquiv hr−1cm−2 larger than the influx measured in the same preparation with mannitol. This difference increases in proportion to the sodium concentration and can be ascribed to diffusion of sodium into a space which is accessible to mannitol but not to inulin during a 30-sec interval. Hence, nearly two-thirds of the previously described linear component of the sodium influx proceeds, as was suspected previously, into a compartment which is not directly connected to net sodium transport across the skin. The nature of the remaining one-third of this linear compartment is not clear but previous experiments suggest that it is also not involved in net sodium transport. | ||
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| 700 | 1 | |a Cruz, Lilia J. |4 oth | |
| 700 | 1 | |a Curran, Peter F. |4 oth | |
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(DE-627)NLEJ207069476 DE-627 ger DE-627 rakwb eng Sodium influx at the outer surface of frog skin 1972 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remaining on the surface of the skin after blotting. The space of distribution for3H-mannitol is about twice as large as the corresponding space for inulin after 32-sec exposure to the tracer. At a sodium concentration of 6.7mm the sodium influx determined with inulin as marker for the test solution is 0.146 μEquiv hr−1cm−2 larger than the influx measured in the same preparation with mannitol. This difference increases in proportion to the sodium concentration and can be ascribed to diffusion of sodium into a space which is accessible to mannitol but not to inulin during a 30-sec interval. Hence, nearly two-thirds of the previously described linear component of the sodium influx proceeds, as was suspected previously, into a compartment which is not directly connected to net sodium transport across the skin. The nature of the remaining one-third of this linear compartment is not clear but previous experiments suggest that it is also not involved in net sodium transport. Springer Online Journal Archives 1860-2002 Biber, Thomas U. L. oth Cruz, Lilia J. oth Curran, Peter F. oth in The journal of membrane biology 1969 7(1972) vom: Jan., Seite 365-376 (DE-627)NLEJ18899419X (DE-600)1459323-3 1432-1424 nnns volume:7 year:1972 month:01 pages:365-376 extent:12 http://dx.doi.org/10.1007/BF01867926 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 7 1972 1 365-376 12 |
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(DE-627)NLEJ207069476 DE-627 ger DE-627 rakwb eng Sodium influx at the outer surface of frog skin 1972 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remaining on the surface of the skin after blotting. The space of distribution for3H-mannitol is about twice as large as the corresponding space for inulin after 32-sec exposure to the tracer. At a sodium concentration of 6.7mm the sodium influx determined with inulin as marker for the test solution is 0.146 μEquiv hr−1cm−2 larger than the influx measured in the same preparation with mannitol. This difference increases in proportion to the sodium concentration and can be ascribed to diffusion of sodium into a space which is accessible to mannitol but not to inulin during a 30-sec interval. Hence, nearly two-thirds of the previously described linear component of the sodium influx proceeds, as was suspected previously, into a compartment which is not directly connected to net sodium transport across the skin. The nature of the remaining one-third of this linear compartment is not clear but previous experiments suggest that it is also not involved in net sodium transport. Springer Online Journal Archives 1860-2002 Biber, Thomas U. L. oth Cruz, Lilia J. oth Curran, Peter F. oth in The journal of membrane biology 1969 7(1972) vom: Jan., Seite 365-376 (DE-627)NLEJ18899419X (DE-600)1459323-3 1432-1424 nnns volume:7 year:1972 month:01 pages:365-376 extent:12 http://dx.doi.org/10.1007/BF01867926 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 7 1972 1 365-376 12 |
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(DE-627)NLEJ207069476 DE-627 ger DE-627 rakwb eng Sodium influx at the outer surface of frog skin 1972 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remaining on the surface of the skin after blotting. The space of distribution for3H-mannitol is about twice as large as the corresponding space for inulin after 32-sec exposure to the tracer. At a sodium concentration of 6.7mm the sodium influx determined with inulin as marker for the test solution is 0.146 μEquiv hr−1cm−2 larger than the influx measured in the same preparation with mannitol. This difference increases in proportion to the sodium concentration and can be ascribed to diffusion of sodium into a space which is accessible to mannitol but not to inulin during a 30-sec interval. Hence, nearly two-thirds of the previously described linear component of the sodium influx proceeds, as was suspected previously, into a compartment which is not directly connected to net sodium transport across the skin. The nature of the remaining one-third of this linear compartment is not clear but previous experiments suggest that it is also not involved in net sodium transport. Springer Online Journal Archives 1860-2002 Biber, Thomas U. L. oth Cruz, Lilia J. oth Curran, Peter F. oth in The journal of membrane biology 1969 7(1972) vom: Jan., Seite 365-376 (DE-627)NLEJ18899419X (DE-600)1459323-3 1432-1424 nnns volume:7 year:1972 month:01 pages:365-376 extent:12 http://dx.doi.org/10.1007/BF01867926 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 7 1972 1 365-376 12 |
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(DE-627)NLEJ207069476 DE-627 ger DE-627 rakwb eng Sodium influx at the outer surface of frog skin 1972 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remaining on the surface of the skin after blotting. The space of distribution for3H-mannitol is about twice as large as the corresponding space for inulin after 32-sec exposure to the tracer. At a sodium concentration of 6.7mm the sodium influx determined with inulin as marker for the test solution is 0.146 μEquiv hr−1cm−2 larger than the influx measured in the same preparation with mannitol. This difference increases in proportion to the sodium concentration and can be ascribed to diffusion of sodium into a space which is accessible to mannitol but not to inulin during a 30-sec interval. Hence, nearly two-thirds of the previously described linear component of the sodium influx proceeds, as was suspected previously, into a compartment which is not directly connected to net sodium transport across the skin. The nature of the remaining one-third of this linear compartment is not clear but previous experiments suggest that it is also not involved in net sodium transport. Springer Online Journal Archives 1860-2002 Biber, Thomas U. L. oth Cruz, Lilia J. oth Curran, Peter F. oth in The journal of membrane biology 1969 7(1972) vom: Jan., Seite 365-376 (DE-627)NLEJ18899419X (DE-600)1459323-3 1432-1424 nnns volume:7 year:1972 month:01 pages:365-376 extent:12 http://dx.doi.org/10.1007/BF01867926 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 7 1972 1 365-376 12 |
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(DE-627)NLEJ207069476 DE-627 ger DE-627 rakwb eng Sodium influx at the outer surface of frog skin 1972 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remaining on the surface of the skin after blotting. The space of distribution for3H-mannitol is about twice as large as the corresponding space for inulin after 32-sec exposure to the tracer. At a sodium concentration of 6.7mm the sodium influx determined with inulin as marker for the test solution is 0.146 μEquiv hr−1cm−2 larger than the influx measured in the same preparation with mannitol. This difference increases in proportion to the sodium concentration and can be ascribed to diffusion of sodium into a space which is accessible to mannitol but not to inulin during a 30-sec interval. Hence, nearly two-thirds of the previously described linear component of the sodium influx proceeds, as was suspected previously, into a compartment which is not directly connected to net sodium transport across the skin. The nature of the remaining one-third of this linear compartment is not clear but previous experiments suggest that it is also not involved in net sodium transport. Springer Online Journal Archives 1860-2002 Biber, Thomas U. L. oth Cruz, Lilia J. oth Curran, Peter F. oth in The journal of membrane biology 1969 7(1972) vom: Jan., Seite 365-376 (DE-627)NLEJ18899419X (DE-600)1459323-3 1432-1424 nnns volume:7 year:1972 month:01 pages:365-376 extent:12 http://dx.doi.org/10.1007/BF01867926 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 7 1972 1 365-376 12 |
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Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remaining on the surface of the skin after blotting. The space of distribution for3H-mannitol is about twice as large as the corresponding space for inulin after 32-sec exposure to the tracer. At a sodium concentration of 6.7mm the sodium influx determined with inulin as marker for the test solution is 0.146 μEquiv hr−1cm−2 larger than the influx measured in the same preparation with mannitol. This difference increases in proportion to the sodium concentration and can be ascribed to diffusion of sodium into a space which is accessible to mannitol but not to inulin during a 30-sec interval. Hence, nearly two-thirds of the previously described linear component of the sodium influx proceeds, as was suspected previously, into a compartment which is not directly connected to net sodium transport across the skin. The nature of the remaining one-third of this linear compartment is not clear but previous experiments suggest that it is also not involved in net sodium transport. |
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Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remaining on the surface of the skin after blotting. The space of distribution for3H-mannitol is about twice as large as the corresponding space for inulin after 32-sec exposure to the tracer. At a sodium concentration of 6.7mm the sodium influx determined with inulin as marker for the test solution is 0.146 μEquiv hr−1cm−2 larger than the influx measured in the same preparation with mannitol. This difference increases in proportion to the sodium concentration and can be ascribed to diffusion of sodium into a space which is accessible to mannitol but not to inulin during a 30-sec interval. Hence, nearly two-thirds of the previously described linear component of the sodium influx proceeds, as was suspected previously, into a compartment which is not directly connected to net sodium transport across the skin. The nature of the remaining one-third of this linear compartment is not clear but previous experiments suggest that it is also not involved in net sodium transport. |
| abstract_unstemmed |
Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remaining on the surface of the skin after blotting. The space of distribution for3H-mannitol is about twice as large as the corresponding space for inulin after 32-sec exposure to the tracer. At a sodium concentration of 6.7mm the sodium influx determined with inulin as marker for the test solution is 0.146 μEquiv hr−1cm−2 larger than the influx measured in the same preparation with mannitol. This difference increases in proportion to the sodium concentration and can be ascribed to diffusion of sodium into a space which is accessible to mannitol but not to inulin during a 30-sec interval. Hence, nearly two-thirds of the previously described linear component of the sodium influx proceeds, as was suspected previously, into a compartment which is not directly connected to net sodium transport across the skin. The nature of the remaining one-third of this linear compartment is not clear but previous experiments suggest that it is also not involved in net sodium transport. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ207069476</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210706220524.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070528s1972 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ207069476</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Sodium influx at the outer surface of frog skin</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1972</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">12</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Summary The unidirectional sodium influx across the outside surface of the frog skin epithelium was measured. The method was identical to the one described by Biber and Curran [4] except that mannitol instead of inulin was used as the indicator for the amount of tracer containing test solution remaining on the surface of the skin after blotting. The space of distribution for3H-mannitol is about twice as large as the corresponding space for inulin after 32-sec exposure to the tracer. At a sodium concentration of 6.7mm the sodium influx determined with inulin as marker for the test solution is 0.146 μEquiv hr−1cm−2 larger than the influx measured in the same preparation with mannitol. This difference increases in proportion to the sodium concentration and can be ascribed to diffusion of sodium into a space which is accessible to mannitol but not to inulin during a 30-sec interval. Hence, nearly two-thirds of the previously described linear component of the sodium influx proceeds, as was suspected previously, into a compartment which is not directly connected to net sodium transport across the skin. The nature of the remaining one-third of this linear compartment is not clear but previous experiments suggest that it is also not involved in net sodium transport.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Springer Online Journal Archives 1860-2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Biber, Thomas U. L.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cruz, Lilia J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Curran, Peter F.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">The journal of membrane biology</subfield><subfield code="d">1969</subfield><subfield code="g">7(1972) vom: Jan., Seite 365-376</subfield><subfield code="w">(DE-627)NLEJ18899419X</subfield><subfield code="w">(DE-600)1459323-3</subfield><subfield code="x">1432-1424</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:7</subfield><subfield code="g">year:1972</subfield><subfield code="g">month:01</subfield><subfield code="g">pages:365-376</subfield><subfield code="g">extent:12</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1007/BF01867926</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SOJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">7</subfield><subfield code="j">1972</subfield><subfield code="c">1</subfield><subfield code="h">365-376</subfield><subfield code="g">12</subfield></datafield></record></collection>
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