Genome Plasticity as a Paradigm of Eubacteria Evolution
Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subti...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
1997 |
|---|
| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
|---|---|
| Übergeordnetes Werk: |
in: Journal of molecular evolution - 1971, 44(1997) vom: Jan., Seite S057 |
| Übergeordnetes Werk: |
volume:44 ; year:1997 ; month:01 ; pages:S057 |
| Links: |
|---|
| Katalog-ID: |
NLEJ207106665 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLEJ207106665 | ||
| 003 | DE-627 | ||
| 005 | 20210706221202.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 070528s1997 xx |||||o 00| ||eng c | ||
| 035 | |a (DE-627)NLEJ207106665 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 245 | 1 | 0 | |a Genome Plasticity as a Paradigm of Eubacteria Evolution |
| 264 | 1 | |c 1997 | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution. | ||
| 533 | |f Springer Online Journal Archives 1860-2002 | ||
| 700 | 1 | |a Watanabe, Hidemi |4 oth | |
| 700 | 1 | |a Mori, Hirotada |4 oth | |
| 700 | 1 | |a Itoh, Takeshi |4 oth | |
| 700 | 1 | |a Gojobori, Takashi |4 oth | |
| 773 | 0 | 8 | |i in |t Journal of molecular evolution |d 1971 |g 44(1997) vom: Jan., Seite S057 |w (DE-627)NLEJ188994645 |w (DE-600)1464309-1 |x 1432-1432 |7 nnns |
| 773 | 1 | 8 | |g volume:44 |g year:1997 |g month:01 |g pages:S057 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/PL00000052 |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a ZDB-1-SOJ | ||
| 912 | |a GBV_NL_ARTICLE | ||
| 951 | |a AR | ||
| 952 | |d 44 |j 1997 |c 1 |h S057 | ||
| matchkey_str |
article:14321432:1997----::eoelsiiysprdgoebce |
|---|---|
| hierarchy_sort_str |
1997 |
| publishDate |
1997 |
| allfields |
(DE-627)NLEJ207106665 DE-627 ger DE-627 rakwb eng Genome Plasticity as a Paradigm of Eubacteria Evolution 1997 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution. Springer Online Journal Archives 1860-2002 Watanabe, Hidemi oth Mori, Hirotada oth Itoh, Takeshi oth Gojobori, Takashi oth in Journal of molecular evolution 1971 44(1997) vom: Jan., Seite S057 (DE-627)NLEJ188994645 (DE-600)1464309-1 1432-1432 nnns volume:44 year:1997 month:01 pages:S057 http://dx.doi.org/10.1007/PL00000052 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 44 1997 1 S057 |
| spelling |
(DE-627)NLEJ207106665 DE-627 ger DE-627 rakwb eng Genome Plasticity as a Paradigm of Eubacteria Evolution 1997 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution. Springer Online Journal Archives 1860-2002 Watanabe, Hidemi oth Mori, Hirotada oth Itoh, Takeshi oth Gojobori, Takashi oth in Journal of molecular evolution 1971 44(1997) vom: Jan., Seite S057 (DE-627)NLEJ188994645 (DE-600)1464309-1 1432-1432 nnns volume:44 year:1997 month:01 pages:S057 http://dx.doi.org/10.1007/PL00000052 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 44 1997 1 S057 |
| allfields_unstemmed |
(DE-627)NLEJ207106665 DE-627 ger DE-627 rakwb eng Genome Plasticity as a Paradigm of Eubacteria Evolution 1997 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution. Springer Online Journal Archives 1860-2002 Watanabe, Hidemi oth Mori, Hirotada oth Itoh, Takeshi oth Gojobori, Takashi oth in Journal of molecular evolution 1971 44(1997) vom: Jan., Seite S057 (DE-627)NLEJ188994645 (DE-600)1464309-1 1432-1432 nnns volume:44 year:1997 month:01 pages:S057 http://dx.doi.org/10.1007/PL00000052 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 44 1997 1 S057 |
| allfieldsGer |
(DE-627)NLEJ207106665 DE-627 ger DE-627 rakwb eng Genome Plasticity as a Paradigm of Eubacteria Evolution 1997 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution. Springer Online Journal Archives 1860-2002 Watanabe, Hidemi oth Mori, Hirotada oth Itoh, Takeshi oth Gojobori, Takashi oth in Journal of molecular evolution 1971 44(1997) vom: Jan., Seite S057 (DE-627)NLEJ188994645 (DE-600)1464309-1 1432-1432 nnns volume:44 year:1997 month:01 pages:S057 http://dx.doi.org/10.1007/PL00000052 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 44 1997 1 S057 |
| allfieldsSound |
(DE-627)NLEJ207106665 DE-627 ger DE-627 rakwb eng Genome Plasticity as a Paradigm of Eubacteria Evolution 1997 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution. Springer Online Journal Archives 1860-2002 Watanabe, Hidemi oth Mori, Hirotada oth Itoh, Takeshi oth Gojobori, Takashi oth in Journal of molecular evolution 1971 44(1997) vom: Jan., Seite S057 (DE-627)NLEJ188994645 (DE-600)1464309-1 1432-1432 nnns volume:44 year:1997 month:01 pages:S057 http://dx.doi.org/10.1007/PL00000052 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 44 1997 1 S057 |
| language |
English |
| source |
in Journal of molecular evolution 44(1997) vom: Jan., Seite S057 volume:44 year:1997 month:01 pages:S057 |
| sourceStr |
in Journal of molecular evolution 44(1997) vom: Jan., Seite S057 volume:44 year:1997 month:01 pages:S057 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| isfreeaccess_bool |
false |
| container_title |
Journal of molecular evolution |
| authorswithroles_txt_mv |
Watanabe, Hidemi @@oth@@ Mori, Hirotada @@oth@@ Itoh, Takeshi @@oth@@ Gojobori, Takashi @@oth@@ |
| publishDateDaySort_date |
1997-01-01T00:00:00Z |
| hierarchy_top_id |
NLEJ188994645 |
| id |
NLEJ207106665 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ207106665</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210706221202.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070528s1997 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ207106665</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Genome Plasticity as a Paradigm of Eubacteria Evolution</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1997</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Springer Online Journal Archives 1860-2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Watanabe, Hidemi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mori, Hirotada</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Itoh, Takeshi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gojobori, Takashi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Journal of molecular evolution</subfield><subfield code="d">1971</subfield><subfield code="g">44(1997) vom: Jan., Seite S057</subfield><subfield code="w">(DE-627)NLEJ188994645</subfield><subfield code="w">(DE-600)1464309-1</subfield><subfield code="x">1432-1432</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:44</subfield><subfield code="g">year:1997</subfield><subfield code="g">month:01</subfield><subfield code="g">pages:S057</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1007/PL00000052</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SOJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">44</subfield><subfield code="j">1997</subfield><subfield code="c">1</subfield><subfield code="h">S057</subfield></datafield></record></collection>
|
| series2 |
Springer Online Journal Archives 1860-2002 |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ188994645 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| collection |
NL |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
1432-1432 |
| topic_title |
Genome Plasticity as a Paradigm of Eubacteria Evolution |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
h w hw h m hm t i ti t g tg |
| hierarchy_parent_title |
Journal of molecular evolution |
| hierarchy_parent_id |
NLEJ188994645 |
| hierarchy_top_title |
Journal of molecular evolution |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)NLEJ188994645 (DE-600)1464309-1 |
| title |
Genome Plasticity as a Paradigm of Eubacteria Evolution |
| spellingShingle |
Genome Plasticity as a Paradigm of Eubacteria Evolution |
| ctrlnum |
(DE-627)NLEJ207106665 |
| title_full |
Genome Plasticity as a Paradigm of Eubacteria Evolution |
| journal |
Journal of molecular evolution |
| journalStr |
Journal of molecular evolution |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
1997 |
| contenttype_str_mv |
zzz |
| container_volume |
44 |
| format_se |
Elektronische Aufsätze |
| title_sort |
genome plasticity as a paradigm of eubacteria evolution |
| title_auth |
Genome Plasticity as a Paradigm of Eubacteria Evolution |
| abstract |
Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution. |
| abstractGer |
Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution. |
| abstract_unstemmed |
Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution. |
| collection_details |
GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE |
| title_short |
Genome Plasticity as a Paradigm of Eubacteria Evolution |
| url |
http://dx.doi.org/10.1007/PL00000052 |
| remote_bool |
true |
| author2 |
Watanabe, Hidemi Mori, Hirotada Itoh, Takeshi Gojobori, Takashi |
| author2Str |
Watanabe, Hidemi Mori, Hirotada Itoh, Takeshi Gojobori, Takashi |
| ppnlink |
NLEJ188994645 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth |
| up_date |
2024-07-06T08:45:45.870Z |
| _version_ |
1803818679267229696 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ207106665</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210706221202.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070528s1997 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ207106665</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Genome Plasticity as a Paradigm of Eubacteria Evolution</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1997</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract. To test the hypotheses that eubacterial genomes leave evolutionarily stable structures and that the variety of genome size is brought about through genome doubling during evolution, the genome structures of Haemophilus influenzae, Mycoplasma genitalium, Escherichia coli, and Bacillus subtilis were compared using the DNA sequences of the entire genome or substantial portions of genome. In these comparisons, the locations of orthologous genes were examined among different genomes. Using orthologous genes for the comparisons guaranteed that differences revealed in physical location would reflect changes in genome structure after speciation. We found that dynamic rearrangements have so frequently occurred in eubacterial genomes as to break operon structures during evolution, even after the relatively recent divergence between E. coli and H. influenzae. Interestingly, in such eubacterial genomes of high plasticity, we could find several highly conservative regions with the longest conserved region comprising the S10, spc, and α operons. This suggests that such exceptional conservative regions have undergone strong structural constraints during evolution.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Springer Online Journal Archives 1860-2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Watanabe, Hidemi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mori, Hirotada</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Itoh, Takeshi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gojobori, Takashi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Journal of molecular evolution</subfield><subfield code="d">1971</subfield><subfield code="g">44(1997) vom: Jan., Seite S057</subfield><subfield code="w">(DE-627)NLEJ188994645</subfield><subfield code="w">(DE-600)1464309-1</subfield><subfield code="x">1432-1432</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:44</subfield><subfield code="g">year:1997</subfield><subfield code="g">month:01</subfield><subfield code="g">pages:S057</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1007/PL00000052</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SOJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">44</subfield><subfield code="j">1997</subfield><subfield code="c">1</subfield><subfield code="h">S057</subfield></datafield></record></collection>
|
| score |
7.4019423 |