Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome
Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytologi...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2000 |
|---|
| Umfang: |
4 |
|---|
| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
|---|---|
| Übergeordnetes Werk: |
in: Modern rheumatology - 2000, 10(2000) vom: Jan., Seite 58-61 |
| Übergeordnetes Werk: |
volume:10 ; year:2000 ; month:01 ; pages:58-61 ; extent:4 |
| Links: |
|---|
| Katalog-ID: |
NLEJ207711593 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLEJ207711593 | ||
| 003 | DE-627 | ||
| 005 | 20230506100539.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 070528s2000 xx |||||o 00| ||eng c | ||
| 035 | |a (DE-627)NLEJ207711593 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 245 | 1 | 0 | |a Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome |
| 264 | 1 | |c 2000 | |
| 300 | |a 4 | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS. | ||
| 533 | |f Springer Online Journal Archives 1860-2002 | ||
| 700 | 1 | |a Shiokawa, S. |4 oth | |
| 700 | 1 | |a Miyazaki, Y. |4 oth | |
| 700 | 1 | |a Nakamura, M. |4 oth | |
| 700 | 1 | |a Nakayama, T. |4 oth | |
| 700 | 1 | |a Ohshima, K. |4 oth | |
| 700 | 1 | |a Suehiro, Y. |4 oth | |
| 700 | 1 | |a Yamamoto, K. |4 oth | |
| 700 | 1 | |a Nishimura, J. |4 oth | |
| 773 | 0 | 8 | |i in |t Modern rheumatology |d 2000 |g 10(2000) vom: Jan., Seite 58-61 |w (DE-627)NLEJ188983651 |w (DE-600)2023498-3 |x 1439-7609 |7 nnns |
| 773 | 1 | 8 | |g volume:10 |g year:2000 |g month:01 |g pages:58-61 |g extent:4 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s101650070041 |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a ZDB-1-SOJ | ||
| 912 | |a GBV_NL_ARTICLE | ||
| 951 | |a AR | ||
| 952 | |d 10 |j 2000 |c 1 |h 58-61 |g 4 | ||
| matchkey_str |
article:14397609:2000----::xasooietclclcoeiteiaeaprtdlnsntericltoiteeihrl |
|---|---|
| hierarchy_sort_str |
2000 |
| publishDate |
2000 |
| allfields |
(DE-627)NLEJ207711593 DE-627 ger DE-627 rakwb eng Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome 2000 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS. Springer Online Journal Archives 1860-2002 Shiokawa, S. oth Miyazaki, Y. oth Nakamura, M. oth Nakayama, T. oth Ohshima, K. oth Suehiro, Y. oth Yamamoto, K. oth Nishimura, J. oth in Modern rheumatology 2000 10(2000) vom: Jan., Seite 58-61 (DE-627)NLEJ188983651 (DE-600)2023498-3 1439-7609 nnns volume:10 year:2000 month:01 pages:58-61 extent:4 http://dx.doi.org/10.1007/s101650070041 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 10 2000 1 58-61 4 |
| spelling |
(DE-627)NLEJ207711593 DE-627 ger DE-627 rakwb eng Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome 2000 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS. Springer Online Journal Archives 1860-2002 Shiokawa, S. oth Miyazaki, Y. oth Nakamura, M. oth Nakayama, T. oth Ohshima, K. oth Suehiro, Y. oth Yamamoto, K. oth Nishimura, J. oth in Modern rheumatology 2000 10(2000) vom: Jan., Seite 58-61 (DE-627)NLEJ188983651 (DE-600)2023498-3 1439-7609 nnns volume:10 year:2000 month:01 pages:58-61 extent:4 http://dx.doi.org/10.1007/s101650070041 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 10 2000 1 58-61 4 |
| allfields_unstemmed |
(DE-627)NLEJ207711593 DE-627 ger DE-627 rakwb eng Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome 2000 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS. Springer Online Journal Archives 1860-2002 Shiokawa, S. oth Miyazaki, Y. oth Nakamura, M. oth Nakayama, T. oth Ohshima, K. oth Suehiro, Y. oth Yamamoto, K. oth Nishimura, J. oth in Modern rheumatology 2000 10(2000) vom: Jan., Seite 58-61 (DE-627)NLEJ188983651 (DE-600)2023498-3 1439-7609 nnns volume:10 year:2000 month:01 pages:58-61 extent:4 http://dx.doi.org/10.1007/s101650070041 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 10 2000 1 58-61 4 |
| allfieldsGer |
(DE-627)NLEJ207711593 DE-627 ger DE-627 rakwb eng Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome 2000 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS. Springer Online Journal Archives 1860-2002 Shiokawa, S. oth Miyazaki, Y. oth Nakamura, M. oth Nakayama, T. oth Ohshima, K. oth Suehiro, Y. oth Yamamoto, K. oth Nishimura, J. oth in Modern rheumatology 2000 10(2000) vom: Jan., Seite 58-61 (DE-627)NLEJ188983651 (DE-600)2023498-3 1439-7609 nnns volume:10 year:2000 month:01 pages:58-61 extent:4 http://dx.doi.org/10.1007/s101650070041 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 10 2000 1 58-61 4 |
| allfieldsSound |
(DE-627)NLEJ207711593 DE-627 ger DE-627 rakwb eng Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome 2000 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS. Springer Online Journal Archives 1860-2002 Shiokawa, S. oth Miyazaki, Y. oth Nakamura, M. oth Nakayama, T. oth Ohshima, K. oth Suehiro, Y. oth Yamamoto, K. oth Nishimura, J. oth in Modern rheumatology 2000 10(2000) vom: Jan., Seite 58-61 (DE-627)NLEJ188983651 (DE-600)2023498-3 1439-7609 nnns volume:10 year:2000 month:01 pages:58-61 extent:4 http://dx.doi.org/10.1007/s101650070041 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 10 2000 1 58-61 4 |
| language |
English |
| source |
in Modern rheumatology 10(2000) vom: Jan., Seite 58-61 volume:10 year:2000 month:01 pages:58-61 extent:4 |
| sourceStr |
in Modern rheumatology 10(2000) vom: Jan., Seite 58-61 volume:10 year:2000 month:01 pages:58-61 extent:4 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| isfreeaccess_bool |
false |
| container_title |
Modern rheumatology |
| authorswithroles_txt_mv |
Shiokawa, S. @@oth@@ Miyazaki, Y. @@oth@@ Nakamura, M. @@oth@@ Nakayama, T. @@oth@@ Ohshima, K. @@oth@@ Suehiro, Y. @@oth@@ Yamamoto, K. @@oth@@ Nishimura, J. @@oth@@ |
| publishDateDaySort_date |
2000-01-01T00:00:00Z |
| hierarchy_top_id |
NLEJ188983651 |
| id |
NLEJ207711593 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ207711593</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506100539.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070528s2000 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ207711593</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2000</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">4</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Springer Online Journal Archives 1860-2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shiokawa, S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Miyazaki, Y.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nakamura, M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nakayama, T.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ohshima, K.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Suehiro, Y.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Yamamoto, K.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nishimura, J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Modern rheumatology</subfield><subfield code="d">2000</subfield><subfield code="g">10(2000) vom: Jan., Seite 58-61</subfield><subfield code="w">(DE-627)NLEJ188983651</subfield><subfield code="w">(DE-600)2023498-3</subfield><subfield code="x">1439-7609</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:10</subfield><subfield code="g">year:2000</subfield><subfield code="g">month:01</subfield><subfield code="g">pages:58-61</subfield><subfield code="g">extent:4</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1007/s101650070041</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SOJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">10</subfield><subfield code="j">2000</subfield><subfield code="c">1</subfield><subfield code="h">58-61</subfield><subfield code="g">4</subfield></datafield></record></collection>
|
| series2 |
Springer Online Journal Archives 1860-2002 |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ188983651 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| collection |
NL |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
1439-7609 |
| topic_title |
Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
s s ss y m ym m n mn t n tn k o ko y s ys k y ky j n jn |
| hierarchy_parent_title |
Modern rheumatology |
| hierarchy_parent_id |
NLEJ188983651 |
| hierarchy_top_title |
Modern rheumatology |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)NLEJ188983651 (DE-600)2023498-3 |
| title |
Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome |
| spellingShingle |
Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome |
| ctrlnum |
(DE-627)NLEJ207711593 |
| title_full |
Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome |
| journal |
Modern rheumatology |
| journalStr |
Modern rheumatology |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
2000 |
| contenttype_str_mv |
zzz |
| container_start_page |
58 |
| container_volume |
10 |
| physical |
4 |
| format_se |
Elektronische Aufsätze |
| title_sort |
expansion of identical b-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with sjögren's syndrome |
| title_auth |
Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome |
| abstract |
Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS. |
| abstractGer |
Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS. |
| abstract_unstemmed |
Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS. |
| collection_details |
GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE |
| title_short |
Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome |
| url |
http://dx.doi.org/10.1007/s101650070041 |
| remote_bool |
true |
| author2 |
Shiokawa, S. Miyazaki, Y. Nakamura, M. Nakayama, T. Ohshima, K. Suehiro, Y. Yamamoto, K. Nishimura, J. |
| author2Str |
Shiokawa, S. Miyazaki, Y. Nakamura, M. Nakayama, T. Ohshima, K. Suehiro, Y. Yamamoto, K. Nishimura, J. |
| ppnlink |
NLEJ188983651 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth oth oth oth oth |
| up_date |
2024-07-06T10:27:53.635Z |
| _version_ |
1803825104693493760 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ207711593</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506100539.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">070528s2000 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ207711593</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Expansion of identical B-cell clones in the bilateral parotid glands and their circulation in the peripheral blood in a patient with Sjögren's syndrome</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2000</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">4</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Springer Online Journal Archives 1860-2002</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shiokawa, S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Miyazaki, Y.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nakamura, M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nakayama, T.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ohshima, K.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Suehiro, Y.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Yamamoto, K.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nishimura, J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">in</subfield><subfield code="t">Modern rheumatology</subfield><subfield code="d">2000</subfield><subfield code="g">10(2000) vom: Jan., Seite 58-61</subfield><subfield code="w">(DE-627)NLEJ188983651</subfield><subfield code="w">(DE-600)2023498-3</subfield><subfield code="x">1439-7609</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:10</subfield><subfield code="g">year:2000</subfield><subfield code="g">month:01</subfield><subfield code="g">pages:58-61</subfield><subfield code="g">extent:4</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1007/s101650070041</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-SOJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">10</subfield><subfield code="j">2000</subfield><subfield code="c">1</subfield><subfield code="h">58-61</subfield><subfield code="g">4</subfield></datafield></record></collection>
|
| score |
7.401496 |