Antimitotic agents and macronuclear division of ciliates
Summary A ciliate protozoan (Tetrahymena pyriformis, amicronucleate strain GL), exposed to 5 mg/ml colchicine to prevent cell division, is able to overcome the initial inhibitory effect of the drug both in exponentially growing and in heat-shock synchronized cultures. Such a regained capability of d...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1970 |
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| Umfang: |
14 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: Protoplasma - 1926, 70(1970) vom: Feb., Seite 139-152 |
| Übergeordnetes Werk: |
volume:70 ; year:1970 ; month:02 ; pages:139-152 ; extent:14 |
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NLEJ208508430 |
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| 520 | |a Summary A ciliate protozoan (Tetrahymena pyriformis, amicronucleate strain GL), exposed to 5 mg/ml colchicine to prevent cell division, is able to overcome the initial inhibitory effect of the drug both in exponentially growing and in heat-shock synchronized cultures. Such a regained capability of division is correlated to the reappearance of colchicine-disordered microtubules in the macronuclei. Electron microscopy reveals a tight connection between the inner nuclear membrane and these macronuclear microtubules. Since a decrease of the colchicine titer in the culture medium could not be established the macronuclear microtubules apparently reassemble in the presence of colchicine. | ||
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| 700 | 1 | |a Speth, V. |4 oth | |
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(DE-627)NLEJ208508430 DE-627 ger DE-627 rakwb eng Antimitotic agents and macronuclear division of ciliates 1970 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A ciliate protozoan (Tetrahymena pyriformis, amicronucleate strain GL), exposed to 5 mg/ml colchicine to prevent cell division, is able to overcome the initial inhibitory effect of the drug both in exponentially growing and in heat-shock synchronized cultures. Such a regained capability of division is correlated to the reappearance of colchicine-disordered microtubules in the macronuclei. Electron microscopy reveals a tight connection between the inner nuclear membrane and these macronuclear microtubules. Since a decrease of the colchicine titer in the culture medium could not be established the macronuclear microtubules apparently reassemble in the presence of colchicine. Springer Online Journal Archives 1860-2002 Wunderlich, F. oth Speth, V. oth in Protoplasma 1926 70(1970) vom: Feb., Seite 139-152 (DE-627)NLEJ188989579 (DE-600)1463033-3 1615-6102 nnns volume:70 year:1970 month:02 pages:139-152 extent:14 http://dx.doi.org/10.1007/BF01276976 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 70 1970 2 139-152 14 |
| spelling |
(DE-627)NLEJ208508430 DE-627 ger DE-627 rakwb eng Antimitotic agents and macronuclear division of ciliates 1970 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A ciliate protozoan (Tetrahymena pyriformis, amicronucleate strain GL), exposed to 5 mg/ml colchicine to prevent cell division, is able to overcome the initial inhibitory effect of the drug both in exponentially growing and in heat-shock synchronized cultures. Such a regained capability of division is correlated to the reappearance of colchicine-disordered microtubules in the macronuclei. Electron microscopy reveals a tight connection between the inner nuclear membrane and these macronuclear microtubules. Since a decrease of the colchicine titer in the culture medium could not be established the macronuclear microtubules apparently reassemble in the presence of colchicine. Springer Online Journal Archives 1860-2002 Wunderlich, F. oth Speth, V. oth in Protoplasma 1926 70(1970) vom: Feb., Seite 139-152 (DE-627)NLEJ188989579 (DE-600)1463033-3 1615-6102 nnns volume:70 year:1970 month:02 pages:139-152 extent:14 http://dx.doi.org/10.1007/BF01276976 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 70 1970 2 139-152 14 |
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(DE-627)NLEJ208508430 DE-627 ger DE-627 rakwb eng Antimitotic agents and macronuclear division of ciliates 1970 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A ciliate protozoan (Tetrahymena pyriformis, amicronucleate strain GL), exposed to 5 mg/ml colchicine to prevent cell division, is able to overcome the initial inhibitory effect of the drug both in exponentially growing and in heat-shock synchronized cultures. Such a regained capability of division is correlated to the reappearance of colchicine-disordered microtubules in the macronuclei. Electron microscopy reveals a tight connection between the inner nuclear membrane and these macronuclear microtubules. Since a decrease of the colchicine titer in the culture medium could not be established the macronuclear microtubules apparently reassemble in the presence of colchicine. Springer Online Journal Archives 1860-2002 Wunderlich, F. oth Speth, V. oth in Protoplasma 1926 70(1970) vom: Feb., Seite 139-152 (DE-627)NLEJ188989579 (DE-600)1463033-3 1615-6102 nnns volume:70 year:1970 month:02 pages:139-152 extent:14 http://dx.doi.org/10.1007/BF01276976 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 70 1970 2 139-152 14 |
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(DE-627)NLEJ208508430 DE-627 ger DE-627 rakwb eng Antimitotic agents and macronuclear division of ciliates 1970 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A ciliate protozoan (Tetrahymena pyriformis, amicronucleate strain GL), exposed to 5 mg/ml colchicine to prevent cell division, is able to overcome the initial inhibitory effect of the drug both in exponentially growing and in heat-shock synchronized cultures. Such a regained capability of division is correlated to the reappearance of colchicine-disordered microtubules in the macronuclei. Electron microscopy reveals a tight connection between the inner nuclear membrane and these macronuclear microtubules. Since a decrease of the colchicine titer in the culture medium could not be established the macronuclear microtubules apparently reassemble in the presence of colchicine. Springer Online Journal Archives 1860-2002 Wunderlich, F. oth Speth, V. oth in Protoplasma 1926 70(1970) vom: Feb., Seite 139-152 (DE-627)NLEJ188989579 (DE-600)1463033-3 1615-6102 nnns volume:70 year:1970 month:02 pages:139-152 extent:14 http://dx.doi.org/10.1007/BF01276976 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 70 1970 2 139-152 14 |
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(DE-627)NLEJ208508430 DE-627 ger DE-627 rakwb eng Antimitotic agents and macronuclear division of ciliates 1970 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A ciliate protozoan (Tetrahymena pyriformis, amicronucleate strain GL), exposed to 5 mg/ml colchicine to prevent cell division, is able to overcome the initial inhibitory effect of the drug both in exponentially growing and in heat-shock synchronized cultures. Such a regained capability of division is correlated to the reappearance of colchicine-disordered microtubules in the macronuclei. Electron microscopy reveals a tight connection between the inner nuclear membrane and these macronuclear microtubules. Since a decrease of the colchicine titer in the culture medium could not be established the macronuclear microtubules apparently reassemble in the presence of colchicine. Springer Online Journal Archives 1860-2002 Wunderlich, F. oth Speth, V. oth in Protoplasma 1926 70(1970) vom: Feb., Seite 139-152 (DE-627)NLEJ188989579 (DE-600)1463033-3 1615-6102 nnns volume:70 year:1970 month:02 pages:139-152 extent:14 http://dx.doi.org/10.1007/BF01276976 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 70 1970 2 139-152 14 |
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Antimitotic agents and macronuclear division of ciliates |
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Summary A ciliate protozoan (Tetrahymena pyriformis, amicronucleate strain GL), exposed to 5 mg/ml colchicine to prevent cell division, is able to overcome the initial inhibitory effect of the drug both in exponentially growing and in heat-shock synchronized cultures. Such a regained capability of division is correlated to the reappearance of colchicine-disordered microtubules in the macronuclei. Electron microscopy reveals a tight connection between the inner nuclear membrane and these macronuclear microtubules. Since a decrease of the colchicine titer in the culture medium could not be established the macronuclear microtubules apparently reassemble in the presence of colchicine. |
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Summary A ciliate protozoan (Tetrahymena pyriformis, amicronucleate strain GL), exposed to 5 mg/ml colchicine to prevent cell division, is able to overcome the initial inhibitory effect of the drug both in exponentially growing and in heat-shock synchronized cultures. Such a regained capability of division is correlated to the reappearance of colchicine-disordered microtubules in the macronuclei. Electron microscopy reveals a tight connection between the inner nuclear membrane and these macronuclear microtubules. Since a decrease of the colchicine titer in the culture medium could not be established the macronuclear microtubules apparently reassemble in the presence of colchicine. |
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Summary A ciliate protozoan (Tetrahymena pyriformis, amicronucleate strain GL), exposed to 5 mg/ml colchicine to prevent cell division, is able to overcome the initial inhibitory effect of the drug both in exponentially growing and in heat-shock synchronized cultures. Such a regained capability of division is correlated to the reappearance of colchicine-disordered microtubules in the macronuclei. Electron microscopy reveals a tight connection between the inner nuclear membrane and these macronuclear microtubules. Since a decrease of the colchicine titer in the culture medium could not be established the macronuclear microtubules apparently reassemble in the presence of colchicine. |
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